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Volumn 62, Issue 5, 2013, Pages 674-683

Nitric oxide synthase inhibitors protect against rotenone-induced, oxidative stress mediated parkinsonism in rats

Author keywords

Behavioral recovery; Hydroxyl radicals; NADPH diaphorase; Neuroprotection; Nitric oxide; Nitric oxide synthase inhibition

Indexed keywords

7 NITROINDAZOLE; AMPHETAMINE; APOMORPHINE; CATALASE; DOPAMINE; GLUTATHIONE; HYDROXYL RADICAL; INDUCIBLE NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; ROTENONE; SUPEROXIDE DISMUTASE; TYROSINE 3 MONOOXYGENASE;

EID: 84875691527     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2013.01.007     Document Type: Article
Times cited : (31)

References (74)
  • 1
    • 81055140360 scopus 로고    scopus 로고
    • Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity
    • A.A. Abdin, and N.I. Sarhan Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity Neurosci. Res. 71 2011 387 395
    • (2011) Neurosci. Res. , vol.71 , pp. 387-395
    • Abdin, A.A.1    Sarhan, N.I.2
  • 2
    • 0037126181 scopus 로고    scopus 로고
    • Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats
    • M. Alam, and W.J. Schmidt Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats Behav. Brain Res. 136 2002 317 324
    • (2002) Behav. Brain Res. , vol.136 , pp. 317-324
    • Alam, M.1    Schmidt, W.J.2
  • 3
    • 0032550199 scopus 로고    scopus 로고
    • Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion
    • A. Almeida, S.J. Heales, J.P. Bolanos, and J.M. Medina Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion Brain Res. 790 1998 209 216
    • (1998) Brain Res. , vol.790 , pp. 209-216
    • Almeida, A.1    Heales, S.J.2    Bolanos, J.P.3    Medina, J.M.4
  • 4
    • 56349089470 scopus 로고    scopus 로고
    • Role of nitric oxide synthases in Parkinson's disease: A review on the antioxidant and anti-inflammatory activity of polyphenols
    • K. Aquilano, S. Baldelli, G. Rotilio, and M.R. Ciriolo Role of nitric oxide synthases in Parkinson's disease: a review on the antioxidant and anti-inflammatory activity of polyphenols Neurochem. Res. 33 2008 2416 2426
    • (2008) Neurochem. Res. , vol.33 , pp. 2416-2426
    • Aquilano, K.1    Baldelli, S.2    Rotilio, G.3    Ciriolo, M.R.4
  • 5
    • 0035449358 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity
    • A. Bal-Price, and G.C. Brown Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity J. Neurosci. 21 2001 6480 6491
    • (2001) J. Neurosci. , vol.21 , pp. 6480-6491
    • Bal-Price, A.1    Brown, G.C.2
  • 6
    • 0035178264 scopus 로고    scopus 로고
    • Role of nitric oxide in a progressive neurodegeneration model of Parkinson's disease in the rat
    • M.K. Barthwal, N. Srivastava, and M. Dikshit Role of nitric oxide in a progressive neurodegeneration model of Parkinson's disease in the rat Redox. Rep. 6 2001 297 302
    • (2001) Redox. Rep. , vol.6 , pp. 297-302
    • Barthwal, M.K.1    Srivastava, N.2    Dikshit, M.3
  • 7
    • 1542513224 scopus 로고    scopus 로고
    • Chronic administration of rotenone increases levels of nitric oxide and lipid peroxidation products in rat brain
    • V. Bashkatova, M. Alam, A. Vanin, and W.J. Schmidt Chronic administration of rotenone increases levels of nitric oxide and lipid peroxidation products in rat brain Exp. Neurol. 186 2004 235 241
    • (2004) Exp. Neurol. , vol.186 , pp. 235-241
    • Bashkatova, V.1    Alam, M.2    Vanin, A.3    Schmidt, W.J.4
  • 9
    • 77956012154 scopus 로고    scopus 로고
    • Nitric oxide and neuronal death
    • G.C. Brown Nitric oxide and neuronal death Nitric oxide 23 2010 153 165
    • (2010) Nitric Oxide , vol.23 , pp. 153-165
    • Brown, G.C.1
  • 10
    • 0041784698 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria
    • G.C. Brown, and A. Bal-Price Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria Mol. Neurobiol. 27 2003 325 355
    • (2003) Mol. Neurobiol. , vol.27 , pp. 325-355
    • Brown, G.C.1    Bal-Price, A.2
  • 11
    • 0028134892 scopus 로고
    • Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase
    • G.C. Brown, and C.E. Cooper Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase FEBS Lett. 356 1994 295 298
    • (1994) FEBS Lett. , vol.356 , pp. 295-298
    • Brown, G.C.1    Cooper, C.E.2
  • 12
    • 0035664304 scopus 로고    scopus 로고
    • Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: Implications for Parkinson's disease
    • S. Canals, M.J. Casarejos, S. de Bernardo, E. Rodriguez-Martin, and M.A. Mena Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease J. Neurochem. 79 2001 1183 1195
    • (2001) J. Neurochem. , vol.79 , pp. 1183-1195
    • Canals, S.1    Casarejos, M.J.2    De Bernardo, S.3    Rodriguez-Martin, E.4    Mena, M.A.5
  • 13
    • 38449088279 scopus 로고    scopus 로고
    • Astrocytes protect MN9D neuronal cells against rotenone-inducedoxidative stress by a glutathione-dependent mechanism
    • Q. Cao, L.R. Wei, L.L. Lu, C.L. Zhao, H.Y. Zhao, and H. Yang Astrocytes protect MN9D neuronal cells against rotenone-inducedoxidative stress by a glutathione-dependent mechanism Sheng Li Xue Bao 25 59 2007 253 259
    • (2007) Sheng Li Xue Bao , vol.25 , Issue.59 , pp. 253-259
    • Cao, Q.1    Wei, L.R.2    Lu, L.L.3    Zhao, C.L.4    Zhao, H.Y.5    Yang, H.6
  • 14
    • 0030938169 scopus 로고    scopus 로고
    • The neuronal nitric oxide synthase inhibitor 7-nitroindazole also inhibits the monoamine oxidase-B-catalyzed oxidation of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine
    • K. Castagnoli, S. Palmer, A. Anderson, T. Bueters, and N. Castagnoli Jr. The neuronal nitric oxide synthase inhibitor 7-nitroindazole also inhibits the monoamine oxidase-B-catalyzed oxidation of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine Chem. Res. Toxicol. 10 1997 364 368
    • (1997) Chem. Res. Toxicol. , vol.10 , pp. 364-368
    • Castagnoli, K.1    Palmer, S.2    Anderson, A.3    Bueters, T.4    Castagnoli, Jr.N.5
  • 16
    • 33749047253 scopus 로고    scopus 로고
    • Reversible inhibition of mitochondrialcomplex i activity following chronic dopaminergic glutathione depletion in vitro: Implications for Parkinson's disease
    • S.J. Chinta, and J.K. Andersen Reversible inhibition of mitochondrialcomplex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease Free Radic. Biol. Med. 41 2006 1442 1448
    • (2006) Free Radic. Biol. Med. , vol.41 , pp. 1442-1448
    • Chinta, S.J.1    Andersen, J.K.2
  • 17
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • P. Chomczynski, and N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal. Biochem. 162 1987 156 159
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 19
    • 2942573598 scopus 로고    scopus 로고
    • Expression of neuronal nitric oxide synthase in brain tissue of hypoxic-ischemic neonatal rat and the cerebral protective effect of neuronal nitric oxide synthase inhibitor 7-nitroindazole
    • G.L. Chu, Y. Xin, J. Cheng, and S.Y. Bi Expression of neuronal nitric oxide synthase in brain tissue of hypoxic-ischemic neonatal rat and the cerebral protective effect of neuronal nitric oxide synthase inhibitor 7-nitroindazole Zhonghua Yi Xue Za Zhi 84 2004 156 158
    • (2004) Zhonghua Yi Xue Za Zhi , vol.84 , pp. 156-158
    • Chu, G.L.1    Xin, Y.2    Cheng, J.3    Bi, S.Y.4
  • 20
    • 0032560572 scopus 로고    scopus 로고
    • Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex i and protective action of glutathione
    • E. Clementi, G.C. Brown, M. Feelisch, and S. Moncada Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione Proc. Natl. Acad. Sci. USA 95 1998 7631 7636
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7631-7636
    • Clementi, E.1    Brown, G.C.2    Feelisch, M.3    Moncada, S.4
  • 21
    • 0029896430 scopus 로고    scopus 로고
    • Attenuation of malonate-induced degeneration of the nigrostriatal pathway by inhibitors of nitric oxide synthase
    • B.P. Connop, R.J. Boegman, R.J. Beninger, and K. Jhamandas Attenuation of malonate-induced degeneration of the nigrostriatal pathway by inhibitors of nitric oxide synthase Neuropharmacology 35 1996 459 465
    • (1996) Neuropharmacology , vol.35 , pp. 459-465
    • Connop, B.P.1    Boegman, R.J.2    Beninger, R.J.3    Jhamandas, K.4
  • 22
    • 0029927787 scopus 로고    scopus 로고
    • Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
    • V.L. Dawson, V.M. Kizushi, P.L. Huang, S.H. Snyder, and T.M. Dawson Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice J. Neurosci. 16 1996 2479 2487
    • (1996) J. Neurosci. , vol.16 , pp. 2479-2487
    • Dawson, V.L.1    Kizushi, V.M.2    Huang, P.L.3    Snyder, S.H.4    Dawson, T.M.5
  • 23
    • 0030930826 scopus 로고    scopus 로고
    • Inhibition of monoamine oxidase contributes to the protective effect of 7-nitroindazole against MPTP neurotoxicity
    • D.A. Di Monte, J.E. Royland, A. Anderson, K. Castagnoli, N. Castagnoli Jr., and J.W. Langston Inhibition of monoamine oxidase contributes to the protective effect of 7-nitroindazole against MPTP neurotoxicity J. Neurochem. 69 1997 1771 1773
    • (1997) J. Neurochem. , vol.69 , pp. 1771-1773
    • Di Monte, D.A.1    Royland, J.E.2    Anderson, A.3    Castagnoli, K.4    Castagnoli, Jr.N.5    Langston, J.W.6
  • 26
    • 84856975752 scopus 로고    scopus 로고
    • Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: Possible implications for Parkinson's disease
    • G. Filomeni, I. Graziani, D. De Zio, L. Dini, D. Centonze, G. Rotilio, and M.R. Ciriolo Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease Neurobiol. Aging 33 2012 767 785
    • (2012) Neurobiol. Aging , vol.33 , pp. 767-785
    • Filomeni, G.1    Graziani, I.2    De Zio, D.3    Dini, L.4    Centonze, D.5    Rotilio, G.6    Ciriolo, M.R.7
  • 27
    • 2342662120 scopus 로고    scopus 로고
    • Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone
    • S.M. Fleming, C. Zhu, P.O. Fernagut, A. Mehta, C.D. DiCarlo, R.L. Seaman, and M.F. Chesselet Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone Exp. Neurol. 187 2004 418 429
    • (2004) Exp. Neurol. , vol.187 , pp. 418-429
    • Fleming, S.M.1    Zhu, C.2    Fernagut, P.O.3    Mehta, A.4    Dicarlo, C.D.5    Seaman, R.L.6    Chesselet, M.F.7
  • 28
    • 78751502344 scopus 로고    scopus 로고
    • HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration
    • H.M. Gao, H. Zhou, F. Zhang, B.C. Wilson, W. Kam, and J.S. Hong HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration J Neurosci. 31 2011 1081 1092
    • (2011) J Neurosci. , vol.31 , pp. 1081-1092
    • Gao, H.M.1    Zhou, H.2    Zhang, F.3    Wilson, B.C.4    Kam, W.5    Hong, J.S.6
  • 29
    • 84865376975 scopus 로고    scopus 로고
    • The effect of adenosine A(2A) receptor antagonists on hydroxyl radical, dopamine, and glutamate in the striatum of rats with altered function of VMAT2
    • K. Gołembiowska, and A. Dziubina The effect of adenosine A(2A) receptor antagonists on hydroxyl radical, dopamine, and glutamate in the striatum of rats with altered function of VMAT2 Neurotox. Res. 22 2012 150 157
    • (2012) Neurotox. Res. , vol.22 , pp. 150-157
    • Gołembiowska, K.1    Dziubina, A.2
  • 32
    • 0001204988 scopus 로고    scopus 로고
    • Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: Potential implications to Parkinson's disease
    • J. Han, F.C. Cheng, Z. Yang, and G. Dryhurst Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: potential implications to Parkinson's disease J. Neurochem. 73 1999 1683 1695
    • (1999) J. Neurochem. , vol.73 , pp. 1683-1695
    • Han, J.1    Cheng, F.C.2    Yang, Z.3    Dryhurst, G.4
  • 35
    • 70450228608 scopus 로고    scopus 로고
    • Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO)
    • T. Herraiz, V.J. Arán, and H. Guillén Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO) Free Radic. Res. 43 2008 975 984
    • (2008) Free Radic. Res. , vol.43 , pp. 975-984
    • Herraiz, T.1    Arán, V.J.2    Guillén, H.3
  • 38
    • 77049095371 scopus 로고    scopus 로고
    • Synergistic anti-Parkinsonism activity of high doses of B vitamins in a chronic cellular model
    • H. Jia, Z. Liu, X. Li, Z. Feng, J. Hao, X. Li, W. Shen, H. Zhang, and J. Liu Synergistic anti-Parkinsonism activity of high doses of B vitamins in a chronic cellular model Neurobiol. Aging 31 2010 636 646
    • (2010) Neurobiol. Aging , vol.31 , pp. 636-646
    • Jia, H.1    Liu, Z.2    Li, X.3    Feng, Z.4    Hao, J.5    Li, X.6    Shen, W.7    Zhang, H.8    Liu, J.9
  • 39
    • 0141500252 scopus 로고    scopus 로고
    • Homocysteine-induced brain lipid peroxidation: Effects of NMDA receptor blockade, antioxidant treatment, and nitric oxide synthase inhibition
    • A. Jara-Prado, A. Ortega-Vazquez, L. Martinez-Ruano, C. Rios, and A. Santamaria Homocysteine-induced brain lipid peroxidation: effects of NMDA receptor blockade, antioxidant treatment, and nitric oxide synthase inhibition Neurotox. Res. 5 2003 237 243
    • (2003) Neurotox. Res. , vol.5 , pp. 237-243
    • Jara-Prado, A.1    Ortega-Vazquez, A.2    Martinez-Ruano, L.3    Rios, C.4    Santamaria, A.5
  • 40
    • 79961208135 scopus 로고    scopus 로고
    • Protective effect of lycopene on oxidative stress and cognitive decline in rotenone induced model of Parkinson's disease
    • H. Kaur, S. Chauhan, and R. Sandhir Protective effect of lycopene on oxidative stress and cognitive decline in rotenone induced model of Parkinson's disease Neurochem. Res. 36 2011 1435 1443
    • (2011) Neurochem. Res. , vol.36 , pp. 1435-1443
    • Kaur, H.1    Chauhan, S.2    Sandhir, R.3
  • 41
    • 84874547093 scopus 로고    scopus 로고
    • Quercetin up-regulates mitochondrial complex-I activity to protect against oxidative stress-mediated apoptotic cell death of dopaminergic neurons
    • Karuppagounder, S.S., Madathil, K.S., Pandey, M., Haobam, R., Usha, R., Mohanakumar, K.P., 2013. Quercetin up-regulates mitochondrial complex-I activity to protect against oxidative stress-mediated apoptotic cell death of dopaminergic neurons. Neuroscience http://dx.doi.org/10.1016/j.neuroscience. 2013.01.032.
    • (2013) Neuroscience
    • Karuppagounder, S.S.1    Madathil, K.S.2    Pandey, M.3    Haobam, R.4    Usha, R.5    Mohanakumar, K.P.6
  • 42
    • 0037424245 scopus 로고    scopus 로고
    • Mitochondrial complex i inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production
    • N. Li, K. Ragheb, G. Lawler, J. Sturgis, B. Rajwa, J.A. Melendez, and J.P. Robinson Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production J. Biol. Chem. 278 2003 8516 8525
    • (2003) J. Biol. Chem. , vol.278 , pp. 8516-8525
    • Li, N.1    Ragheb, K.2    Lawler, G.3    Sturgis, J.4    Rajwa, B.5    Melendez, J.A.6    Robinson, J.P.7
  • 44
    • 39149122800 scopus 로고    scopus 로고
    • Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-inducedparkinsonian rats
    • C.H. Lin, J.Y. Huang, C.H. Ching, and J.I. Chuang Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-inducedparkinsonian rats J. Pineal Res. 44 2008 205 213
    • (2008) J. Pineal Res. , vol.44 , pp. 205-213
    • Lin, C.H.1    Huang, J.Y.2    Ching, C.H.3    Chuang, J.I.4
  • 45
    • 0031795877 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase-2 in glia associated with CNS pathology
    • A.K. Loihl, and S. Murphy Expression of nitric oxide synthase-2 in glia associated with CNS pathology Prog. Brain Res. 118 1998 253 267
    • (1998) Prog. Brain Res. , vol.118 , pp. 253-267
    • Loihl, A.K.1    Murphy, S.2
  • 47
    • 0031003702 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibition and MPTP-induced toxicity in the common marmoset
    • G.M. Mackenzie, M.J. Jackson, P. Jenner, and C.D. Marsden Nitric oxide synthase inhibition and MPTP-induced toxicity in the common marmoset Synapse 26 1997 301 316
    • (1997) Synapse , vol.26 , pp. 301-316
    • Mackenzie, G.M.1    Jackson, M.J.2    Jenner, P.3    Marsden, C.D.4
  • 48
    • 84879556282 scopus 로고    scopus 로고
    • Sodium salicylate protects against rotenone-induced parkinsonism in rats
    • (under revision)
    • Madathil, K.S., Saravanan, K.S., Mohanakumar, K.P., 2013. Sodium salicylate protects against rotenone-induced parkinsonism in rats. Synapse (under revision).
    • (2013) Synapse
    • Madathil, K.S.1    Saravanan, K.S.2    Mohanakumar, K.P.3
  • 49
    • 17544393549 scopus 로고    scopus 로고
    • Neuroprotection by nitric oxide against hydroxyl radical-induced nigral neurotoxicity
    • K.P. Mohanakumar, I. Hanbauer, and C.C. Chiueh Neuroprotection by nitric oxide against hydroxyl radical-induced nigral neurotoxicity J. Chem. Neuroanat. 14 1998 195 205
    • (1998) J. Chem. Neuroanat. , vol.14 , pp. 195-205
    • Mohanakumar, K.P.1    Hanbauer, I.2    Chiueh, C.C.3
  • 50
    • 0031801548 scopus 로고    scopus 로고
    • Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity in mice
    • D. Muralikrishnan, and K.P. Mohanakumar Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice FASEB J. 12 1998 905 912
    • (1998) FASEB J. , vol.12 , pp. 905-912
    • Muralikrishnan, D.1    Mohanakumar, K.P.2
  • 52
    • 0033592133 scopus 로고    scopus 로고
    • 7-Nitroindazole prevents 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine- induced ATP loss in the mouse striatum
    • J.E. Royland, K. Delfani, J.W. Langston, A.M. Janson, and D.A. Di Monte 7-Nitroindazole prevents 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced ATP loss in the mouse striatum Brain Res. 839 1999 41 48
    • (1999) Brain Res. , vol.839 , pp. 41-48
    • Royland, J.E.1    Delfani, K.2    Langston, J.W.3    Janson, A.M.4    Di Monte, D.A.5
  • 53
    • 80052273858 scopus 로고    scopus 로고
    • Calpain inhibition protected spinal cord motoneurons against 1-methyl-4-phenylpyridinium ion and rotenone
    • S. Samantaray, V.H. Knaryan, C. Le Gal, S.K. Ray, and N.L. Banik Calpain inhibition protected spinal cord motoneurons against 1-methyl-4-phenylpyridinium ion and rotenone Neuroscience 192 2011 263 274
    • (2011) Neuroscience , vol.192 , pp. 263-274
    • Samantaray, S.1    Knaryan, V.H.2    Le Gal, C.3    Ray, S.K.4    Banik, N.L.5
  • 54
    • 23044486663 scopus 로고    scopus 로고
    • Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease
    • K.S. Saravanan, K.M. Sindhu, and K.P. Mohanakumar Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease Brain. Res. 1049 2005 147 155
    • (2005) Brain. Res. , vol.1049 , pp. 147-155
    • Saravanan, K.S.1    Sindhu, K.M.2    Mohanakumar, K.P.3
  • 55
    • 33646527553 scopus 로고    scopus 로고
    • L-Deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats
    • K.S. Saravanan, K.M. Sindhu, K.S. Senthilkumar, and K.P. Mohanakumar l-Deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats Neurochem. Int. 49 2006 28 40
    • (2006) Neurochem. Int. , vol.49 , pp. 28-40
    • Saravanan, K.S.1    Sindhu, K.M.2    Senthilkumar, K.S.3    Mohanakumar, K.P.4
  • 56
    • 33847675291 scopus 로고    scopus 로고
    • Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model
    • K.S. Saravanan, K.M. Sindhu, and K.P. Mohanakumar Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model J. Pineal Res. 42 2007 247 253
    • (2007) J. Pineal Res. , vol.42 , pp. 247-253
    • Saravanan, K.S.1    Sindhu, K.M.2    Mohanakumar, K.P.3
  • 57
  • 58
    • 0031589740 scopus 로고    scopus 로고
    • Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex i inhibitors
    • T.A. Seaton, J.M. Cooper, and A.H. Schapira Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors Brain Res. 777 1997 110 118
    • (1997) Brain Res. , vol.777 , pp. 110-118
    • Seaton, T.A.1    Cooper, J.M.2    Schapira, A.H.3
  • 59
    • 74849095736 scopus 로고    scopus 로고
    • Effects of chronic low dose rotenone treatment on human microglial cells
    • S.B. Shaikh, and L.F. Nicholson Effects of chronic low dose rotenone treatment on human microglial cells Mol. Neurodegener. 31 4 2009 55
    • (2009) Mol. Neurodegener. , vol.31 , Issue.4 , pp. 55
    • Shaikh, S.B.1    Nicholson, L.F.2
  • 60
    • 22144431587 scopus 로고    scopus 로고
    • Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion
    • K.M. Sindhu, K.S. Saravanan, and K.P. Mohanakumar Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion Brain Res. 1051 2005 25 34
    • (2005) Brain Res. , vol.1051 , pp. 25-34
    • Sindhu, K.M.1    Saravanan, K.S.2    Mohanakumar, K.P.3
  • 61
    • 33746493307 scopus 로고    scopus 로고
    • Rats with unilateral median forebrain bundle, but not striatal or nigral, lesions by the neurotoxins MPP+ or rotenone display differential sensitivity to amphetamine and apomorphine
    • K.M. Sindhu, R. Banerjee, K.S. Senthilkumar, K.S. Saravanan, B. China Raju, J. Madhusudan Rao, and K.P. Mohanakumar Rats with unilateral median forebrain bundle, but not striatal or nigral, lesions by the neurotoxins MPP+ or rotenone display differential sensitivity to amphetamine and apomorphine Pharmacol. Biochem. Behav. 84 2006 321 329
    • (2006) Pharmacol. Biochem. Behav. , vol.84 , pp. 321-329
    • Sindhu, K.M.1    Banerjee, R.2    Senthilkumar, K.S.3    Saravanan, K.S.4    China Raju, B.5    Madhusudan Rao, J.6    Mohanakumar, K.P.7
  • 62
    • 0037269343 scopus 로고    scopus 로고
    • Quantitative relationship between inhibition of respiratory complexes and formation of reactive oxygen species in isolated nerve terminals
    • I. Sipos, L. Tretter, and V. Adam-Vizi Quantitative relationship between inhibition of respiratory complexes and formation of reactive oxygen species in isolated nerve terminals J. Neurochem. 84 2003 112 118
    • (2003) J. Neurochem. , vol.84 , pp. 112-118
    • Sipos, I.1    Tretter, L.2    Adam-Vizi, V.3
  • 63
    • 0030882784 scopus 로고    scopus 로고
    • Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions
    • T.S. Smith, and J.P. Bennett Jr. Mitochondrial toxins in models of neurodegenerative diseases. I: in vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions Brain Res. 765 1997 183 188
    • (1997) Brain Res. , vol.765 , pp. 183-188
    • Smith, T.S.1    Bennett, Jr.J.P.2
  • 64
    • 84863348583 scopus 로고    scopus 로고
    • N-acetylcysteine protects against apoptosis through modulation of group i metabotropic glutamate receptor activity
    • L. Sun, L. Gu, S. Wang, J. Yuan, H. Yang, J. Zhu, and H. Zhang N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity PLoSOne 7 2012 e32503
    • (2012) PLoSOne , vol.7 , pp. 32503
    • Sun, L.1    Gu, L.2    Wang, S.3    Yuan, J.4    Yang, H.5    Zhu, J.6    Zhang, H.7
  • 65
    • 67650094606 scopus 로고    scopus 로고
    • Effect of centrophenoxine against rotenone-inducedoxidative stress in an animal model of Parkinson's disease
    • R. Verma, and B. Nehru Effect of centrophenoxine against rotenone-inducedoxidative stress in an animal model of Parkinson's disease Neurochem. Int. 55 2009 369 375
    • (2009) Neurochem. Int. , vol.55 , pp. 369-375
    • Verma, R.1    Nehru, B.2
  • 66
    • 18144427184 scopus 로고    scopus 로고
    • 2+-induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex i
    • 2+-induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex I J. Neurochem. 93 2005 526 537
    • (2005) J. Neurochem. , vol.93 , pp. 526-537
    • Votyakova, T.V.1    Reynolds, I.J.2
  • 67
    • 52949101301 scopus 로고    scopus 로고
    • Mitochondrial complex i inhibitor rotenone inhibits and redistributes vesicular monoamine transporter 2 via nitration in human dopaminergic SH-SY5Y cells
    • M. Watabe, and T. Nakaki Mitochondrial complex I inhibitor rotenone inhibits and redistributes vesicular monoamine transporter 2 via nitration in human dopaminergic SH-SY5Y cells Mol. Pharmacol. 74 2008 933 940
    • (2008) Mol. Pharmacol. , vol.74 , pp. 933-940
    • Watabe, M.1    Nakaki, T.2
  • 68
    • 0842285444 scopus 로고    scopus 로고
    • Protective effects of neuronal nitric oxide synthase inhibitor in mouse brain against MPTP neurotoxicity: An immunohistological study
    • H. Watanabe, Y. Muramatsu, R. Kurosaki, M. Michimata, M. Matsubara, Y. Imai, and T. Araki Protective effects of neuronal nitric oxide synthase inhibitor in mouse brain against MPTP neurotoxicity: an immunohistological study Eur. Neuropsychopharmacol. 14 2004 93 104
    • (2004) Eur. Neuropsychopharmacol. , vol.14 , pp. 93-104
    • Watanabe, H.1    Muramatsu, Y.2    Kurosaki, R.3    Michimata, M.4    Matsubara, M.5    Imai, Y.6    Araki, T.7
  • 69
    • 39149086019 scopus 로고    scopus 로고
    • Protective action of neuronal nitric oxide synthase inhibitor in the MPTP mouse model of Parkinson's disease
    • Y. Watanabe, H. Kato, and T. Araki Protective action of neuronal nitric oxide synthase inhibitor in the MPTP mouse model of Parkinson's disease Metab. Brain Dis. 23 2008 51 69
    • (2008) Metab. Brain Dis. , vol.23 , pp. 51-69
    • Watanabe, Y.1    Kato, H.2    Araki, T.3
  • 70
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
    • D.C. Wu, V. Jackson-Lewis, M. Vila, K. Tieu, V. Teismann, C. Vadseth, D.K. Choi, H. Ischiropoulos, and S. Przedborski Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson disease J. Neurosci. 22 2002 1763 1771
    • (2002) J. Neurosci. , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3    Tieu, K.4    Teismann, V.5    Vadseth, C.6    Choi, D.K.7    Ischiropoulos, H.8    Przedborski, S.9
  • 72
    • 80053943300 scopus 로고    scopus 로고
    • Acetyl-l-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy
    • S.A. Zaitone, D.M. Abo-Elmatty, and A.A. Shaalan Acetyl-l-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy Pharmacol. Biochem. Behav. 100 2012 347 360
    • (2012) Pharmacol. Biochem. Behav. , vol.100 , pp. 347-360
    • Zaitone, S.A.1    Abo-Elmatty, D.M.2    Shaalan, A.A.3
  • 73
    • 77951950272 scopus 로고    scopus 로고
    • Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease
    • H. Zhang, H. Jia, J. Liu, N. Ao, B. Yan, W. Shen, X. Wang, X. Li, C. Luo, and J. Liu Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease J. Cell. Mol. Med. 14 2010 215 225
    • (2010) J. Cell. Mol. Med. , vol.14 , pp. 215-225
    • Zhang, H.1    Jia, H.2    Liu, J.3    Ao, N.4    Yan, B.5    Shen, W.6    Wang, X.7    Li, X.8    Luo, C.9    Liu, J.10


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