메뉴 건너뛰기




Volumn 12, Issue 10, 1998, Pages 905-912

Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity in mice

Author keywords

Antioxidant enzymes; Dopamine neurotoxicity; Free radical scavenger; GSH; Hydroxyl radicals; MPTP; Neuroprotection

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ANTIOXIDANT; BROMOCRIPTINE; CATALASE; DOPAMINE; DOPAMINE RECEPTOR; GLUTATHIONE; HYDROXYL RADICAL; SCAVENGER; SUPEROXIDE DISMUTASE;

EID: 0031801548     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (214)

References (51)
  • 1
    • 0001496694 scopus 로고
    • A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl1,2,3,6-tetrahydropyridine
    • Burns, R. S., Chinch, C. C., Markey, S. P., Ebert, M. H., Jacobowitz, D. M., and Kopin, I. J. (1983) A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl1,2,3,6-tetrahydropyridine. Proc. Natl. Acad. Sci. USA 80, 4546-4550
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4546-4550
    • Burns, R.S.1    Chinch, C.C.2    Markey, S.P.3    Ebert, M.H.4    Jacobowitz, D.M.5    Kopin, I.J.6
  • 2
    • 0021280826 scopus 로고
    • Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
    • Heikkila, R. E., Hess, A. G., and Duvoisin, R. C. (1984) Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Science 224, 1451-1453
    • (1984) Science , vol.224 , pp. 1451-1453
    • Heikkila, R.E.1    Hess, A.G.2    Duvoisin, R.C.3
  • 3
    • 0028208737 scopus 로고
    • Resistance of golden hamster to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Relationship with low levels of regional monoamine oxidase-B
    • Mitra, N., Mohanakumar, K. P., and Ganguly, D. K. (1994) Resistance of golden hamster to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Relationship with low levels of regional monoamine oxidase-B. J. Neurochem. 62, 1906-1912
    • (1994) J. Neurochem. , vol.62 , pp. 1906-1912
    • Mitra, N.1    Mohanakumar, K.P.2    Ganguly, D.K.3
  • 4
    • 0000340348 scopus 로고
    • Parkinsonism-inducing neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenyl pyridinium by dopamine neurons explains selective toxicity
    • Javitch, J. A., D'Amato, R. I., Strittmater, S. M., and Snyder, S. H. (1985) Parkinsonism-inducing neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: uptake of the metabolite N-methyl-4-phenyl pyridinium by dopamine neurons explains selective toxicity. Proc. Natl. Acad. Sci. USA 82, 2173-2177
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2173-2177
    • Javitch, J.A.1    D'Amato, R.I.2    Strittmater, S.M.3    Snyder, S.H.4
  • 5
    • 0027504297 scopus 로고
    • Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds
    • Tipton, K. F., and Singer, T. P. (1993) Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds. J. Neurochem. 61, 1191-1206
    • (1993) J. Neurochem. , vol.61 , pp. 1191-1206
    • Tipton, K.F.1    Singer, T.P.2
  • 8
    • 0016378870 scopus 로고
    • The generation of hydrogen peroxide, superoxide radical and hydroxyl radical by 6-hydroxydopamine, dialoric acid and related cytotoxic agents
    • Cohen, G., and Heikkila, R. E. (1974) The generation of hydrogen peroxide, superoxide radical and hydroxyl radical by 6-hydroxydopamine, dialoric acid and related cytotoxic agents. J. Biol. Chem. 249, 2447-2452
    • (1974) J. Biol. Chem. , vol.249 , pp. 2447-2452
    • Cohen, G.1    Heikkila, R.E.2
  • 9
    • 0024520513 scopus 로고
    • Central nervous system trauma and stroke. 1. Biochemical considerations for oxygen radical formation and lipid peroxidation
    • Braughler, J. M., and Hall, E. D. (1989) Central nervous system trauma and stroke. 1. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Radical Biol. Med. 6, 289-301
    • (1989) Free Radical Biol. Med. , vol.6 , pp. 289-301
    • Braughler, J.M.1    Hall, E.D.2
  • 10
    • 0028610044 scopus 로고
    • Neuroprotection by antioxidants in models of global and focal ischemia
    • Clemens, J. A., and Panetta, J. A. (1994) Neuroprotection by antioxidants in models of global and focal ischemia. Ann. N.Y. Acad. Sci. 738, 250-256
    • (1994) Ann. N.Y. Acad. Sci. , vol.738 , pp. 250-256
    • Clemens, J.A.1    Panetta, J.A.2
  • 13
  • 15
    • 0027953004 scopus 로고
    • Antioxidant properties of bromocriptine, a dopamine agonist
    • Yoshikawa, T., Minamiyama, Y., Naito, Y., and Kondo, M. (1994) Antioxidant properties of bromocriptine, a dopamine agonist. J. Neurochem. 62, 1034-1038
    • (1994) J. Neurochem. , vol.62 , pp. 1034-1038
    • Yoshikawa, T.1    Minamiyama, Y.2    Naito, Y.3    Kondo, M.4
  • 16
    • 0028068121 scopus 로고
    • Bromocriptine protects mice against 6-hydroxydopamine and scavenges hydroxyl free radicals in vitro
    • Ogawu, N., Tanaka, K., Asanuma, M., Kawai, M., Masumizu, T., Kohno, M., and Mori, A. (1994) Bromocriptine protects mice against 6-hydroxydopamine and scavenges hydroxyl free radicals in vitro. Brain Res. 657, 207-213
    • (1994) Brain Res. , vol.657 , pp. 207-213
    • Ogawu, N.1    Tanaka, K.2    Asanuma, M.3    Kawai, M.4    Masumizu, T.5    Kohno, M.6    Mori, A.7
  • 17
    • 0028625335 scopus 로고
    • Bromocriptine scavenges methamphetamine-induced hydroxyl radicals and attenuates dopamine depiction in mouse sirialiun
    • Kondo, T., Ito, T., and Sugita, Y. (1094) Bromocriptine scavenges methamphetamine-induced hydroxyl radicals and attenuates dopamine depiction in mouse sirialiun. Ann. N.Y. Acad. Sci. 738, 222-229
    • (1094) Ann. N.Y. Acad. Sci. , vol.738 , pp. 222-229
    • Kondo, T.1    Ito, T.2    Sugita, Y.3
  • 18
    • 0028882139 scopus 로고
    • Differential effects of three dopamine receptor agonists in MPTP-treated monkeys
    • Aral, N., Isaji, M., Miyata, H., Fukuyama, J., Minuta, E., and Kuno, S. (1995) Differential effects of three dopamine receptor agonists in MPTP-treated monkeys. J. Neural Transm. 10, 55-62
    • (1995) J. Neural Transm. , vol.10 , pp. 55-62
    • Aral, N.1    Isaji, M.2    Miyata, H.3    Fukuyama, J.4    Minuta, E.5    Kuno, S.6
  • 19
    • 0025257126 scopus 로고
    • Effect of chronic treatment of MPTP monkeys with dopamine D-1 and/ or D-2 receptor agonists
    • Gagnon, C., Bedard, P. J., and Di Paolo, T. (1990) Effect of chronic treatment of MPTP monkeys with dopamine D-1 and/ or D-2 receptor agonists. Eur. J. Pharmacol 178, 115-120
    • (1990) Eur. J. Pharmacol , vol.178 , pp. 115-120
    • Gagnon, C.1    Bedard, P.J.2    Di Paolo, T.3
  • 21
    • 0026563594 scopus 로고
    • Dissociation of serotoninergic and dopaminergic components in acute effects of 1-meuiyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
    • Mitra, N., Mohanakumar, K. P., and Ganguly, D. K. (1992) Dissociation of serotoninergic and dopaminergic components in acute effects of 1-meuiyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.Brain Res. Bull.28, 355-364
    • (1992) Brain Res. Bull. , vol.28 , pp. 355-364
    • Mitra, N.1    Mohanakumar, K.P.2    Ganguly, D.K.3
  • 22
    • 0023837991 scopus 로고
    • Acute stress or neuroleptics elicit sensorimotor deficits in MPTP-treated mice
    • Weimuller, F. B., Hadjiconstantinou, M., and Bruno, J. P. (1988) Acute stress or neuroleptics elicit sensorimotor deficits in MPTP-treated mice. Neurosci. Lett. 85, 137-142
    • (1988) Neurosci. Lett. , vol.85 , pp. 137-142
    • Weimuller, F.B.1    Hadjiconstantinou, M.2    Bruno, J.P.3
  • 23
    • 0025608819 scopus 로고
    • Tremorogenesis by physostigmine is unrelated to acetylcholinesterase inhibition: Evidence for serotoninergic involvement
    • Mohanakumar, K. P., Mitra, N., and Ganguly, D. K. (1990) Tremorogenesis by physostigmine is unrelated to acetylcholinesterase inhibition: evidence for serotoninergic involvement. Neurosci. Lett. 120, 91-93
    • (1990) Neurosci. Lett. , vol.120 , pp. 91-93
    • Mohanakumar, K.P.1    Mitra, N.2    Ganguly, D.K.3
  • 24
    • 0025733745 scopus 로고
    • Hydroxylation of salicylate as an assay for hydroxyl radicals: A cautionary note
    • Halliwell, B., Kaur, H., and Ingelman-Sundberg, M. (1991) Hydroxylation of salicylate as an assay for hydroxyl radicals: a cautionary note. Free Radical Biol. Med. 10, 439-441
    • (1991) Free Radical Biol. Med. , vol.10 , pp. 439-441
    • Halliwell, B.1    Kaur, H.2    Ingelman-Sundberg, M.3
  • 25
    • 0016272750 scopus 로고
    • Involvement of superoxide anion radical in die autoxichuion of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund, S., and Markhmd, G. (1974) Involvement of superoxide anion radical in die autoxichuion of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 47, 469-474
    • (1974) Eur. J. Biochem. , vol.47 , pp. 469-474
    • Marklund, S.1    Markhmd, G.2
  • 26
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi, H. (1984) Catalase in vitro. Methods Enzymol. 105, 121-126
    • (1984) Methods Enzymol. , vol.105 , pp. 121-126
    • Aebi, H.1
  • 27
    • 0013893023 scopus 로고
    • A fluorimetric assay for glutathione
    • Cohn, V. H., and Lyle, J. (1966) A fluorimetric assay for glutathione. Anal. Biochcm. 14, 434-440
    • (1966) Anal. Biochcm. , vol.14 , pp. 434-440
    • Cohn, V.H.1    Lyle, J.2
  • 28
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 31
    • 0022475372 scopus 로고
    • Lipid peroxidation as cause of nigral cell death in Parkinson's disease
    • Dexter, D., Carter, C., Agid, F., Agid, Y., Lees, A. J., Jenner, P., and Marsden, C. D. (1986) Lipid peroxidation as cause of nigral cell death in Parkinson's disease. Lancet ii, 639-640
    • (1986) Lancet , vol.2 , pp. 639-640
    • Dexter, D.1    Carter, C.2    Agid, F.3    Agid, Y.4    Lees, A.J.5    Jenner, P.6    Marsden, C.D.7
  • 32
    • 0020308323 scopus 로고
    • Parkinson's disease: A disorder due to nigral glutathione deficiency?
    • Perry, T. L., Godin, D. V., and Hansen, S. (1982) Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci. Lett. 33, 305-310
    • (1982) Neurosci. Lett. , vol.33 , pp. 305-310
    • Perry, T.L.1    Godin, D.V.2    Hansen, S.3
  • 33
    • 0022415447 scopus 로고
    • Glutathione peroxidase activity in Parkinson's disease brain
    • Kish, S. J., Morito, C., and Hornykiewicz, O. (1985) Glutathione peroxidase activity in Parkinson's disease brain. Neurosci. Lett. 58, 343-346
    • (1985) Neurosci. Lett. , vol.58 , pp. 343-346
    • Kish, S.J.1    Morito, C.2    Hornykiewicz, O.3
  • 34
    • 0016652087 scopus 로고
    • Bruin peroxidase and catalase in Parkinson's disease
    • Ambani, L. M., Van Woert, M. H., and Murphy, S. (1975) Bruin peroxidase and catalase in Parkinson's disease. Arch. Neurol. 32, 114-118
    • (1975) Arch. Neurol. , vol.32 , pp. 114-118
    • Ambani, L.M.1    Van Woert, M.H.2    Murphy, S.3
  • 35
    • 0028045734 scopus 로고
    • Increased iron in the substantia nigra compacta of the MPTP-lesioned hemiparkinsonian green monkey: Evidence from proton microprobe elemental microanalysis
    • Temlett, J. A. Landsberg, P., Watt, F., and Grime, G. W. (1994) Increased iron in the substantia nigra compacta of the MPTP-lesioned hemiparkinsonian green monkey: evidence from proton microprobe elemental microanalysis. J. Neurochem. 62, 134-146
    • (1994) J. Neurochem. , vol.62 , pp. 134-146
    • Temlett, J.A.1    Landsberg, P.2    Watt, F.3    Grime, G.W.4
  • 36
    • 0028266425 scopus 로고
    • Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) -induced hemiparkinsonian monkeys
    • Mochizuki, H., Imai, H., Eudo, K., Yokomizo, K., Murata, Y., Hattori, N., and Mizuno, Y. (1994) Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) -induced hemiparkinsonian monkeys. Neurosci. Lett. 168, 251-253
    • (1994) Neurosci. Lett. , vol.168 , pp. 251-253
    • Mochizuki, H.1    Imai, H.2    Eudo, K.3    Yokomizo, K.4    Murata, Y.5    Hattori, N.6    Mizuno, Y.7
  • 37
    • 0024589671 scopus 로고
    • Mitochondria covered with a net of parallel and latticed filaments in nigral neurons of monkeys with experimental parkinsonism
    • Nakamuni, H., Kato, S., and Tanaka, J. (1989) Mitochondria covered with a net of parallel and latticed filaments in nigral neurons of monkeys with experimental parkinsonism. Acta Neuropathol 77, 489-493
    • (1989) Acta Neuropathol , vol.77 , pp. 489-493
    • Nakamuni, H.1    Kato, S.2    Tanaka, J.3
  • 38
    • 0023694019 scopus 로고
    • Inhibition of mitochondrial respiration by 1-methyl-4-pheriyl-1,2,3;6-tetrahydropyridine in mouse brain in vivo
    • Mizuno, Y., Suzuki, K., Sone, N., and Saitoh, T. (1988) Inhibition of mitochondrial respiration by 1-methyl-4-pheriyl-1,2,3;6-tetrahydropyridine in mouse brain in vivo. Neurosci. Lett. 91, 349-353
    • (1988) Neurosci. Lett. , vol.91 , pp. 349-353
    • Mizuno, Y.1    Suzuki, K.2    Sone, N.3    Saitoh, T.4
  • 40
    • 0032144780 scopus 로고    scopus 로고
    • Manganese: A transition metal protects nigrostriatal neurons from oxidative stress in the iron-induced animal model of parkinsonism
    • In press
    • Sziraki, I., Mohanakumar, K. P., Rauhala, P., Kim, H. G., Yeh, K. J., and Chiueh, C. C. (1998) Manganese: a transition metal protects nigrostriatal neurons from oxidative stress in the iron-induced animal model of parkinsonism. Neuroscience In press
    • (1998) Neuroscience
    • Sziraki, I.1    Mohanakumar, K.P.2    Rauhala, P.3    Kim, H.G.4    Yeh, K.J.5    Chiueh, C.C.6
  • 41
    • 0021276089 scopus 로고
    • Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
    • Chiba, K., Trevor, A., and Castagnoli, N., Jr. (1984) Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase. Biochem. Biophys. to. Commun. 120, 574-578
    • (1984) Biochem. Biophys. to Commun. , vol.120 , pp. 574-578
    • Chiba, K.1    Trevor, A.2    Castagnoli Jr., N.3
  • 42
    • 0027304263 scopus 로고
    • Generation of reactive oxygen species during the monoainine oxidase-catalyzed oxidation of the neurotoxicam 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Zang, L. Y., and Misra, H. P. (1993) Generation of reactive oxygen species during the monoainine oxidase-catalyzed oxidation of the neurotoxicam 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J. Biol. Chem. 268, 16504-16512
    • (1993) J. Biol. Chem. , vol.268 , pp. 16504-16512
    • Zang, L.Y.1    Misra, H.P.2
  • 44
    • 0028971624 scopus 로고
    • Effects of MPTP and Ixleprenyl on antioxidant enzymes and lipid peroxidation levels in mouse brain
    • Thifiault, C., Aumont, N., Quirion, R., and Poirier, J. (1905) Effects of MPTP and Ixleprenyl on antioxidant enzymes and lipid peroxidation levels in mouse brain. J. Neurochem. 65, 2725-2733
    • (1905) J. Neurochem. , vol.65 , pp. 2725-2733
    • Thifiault, C.1    Aumont, N.2    Quirion, R.3    Poirier, J.4
  • 46
    • 0027361063 scopus 로고
    • Sulfhydryl drugs reduce neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-toirahydopyridine (MPTP) in the mouse
    • Oishi, T., Hasegawa, E., and Murai, T. (1993) Sulfhydryl drugs reduce neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-toirahydopyridine (MPTP) in the mouse. J. Neural Transm. Parkinson's Dis. Dementia Sect. 6, 45-52
    • (1993) J. Neural Transm. Parkinson's Dis. Dementia Sect. , vol.6 , pp. 45-52
    • Oishi, T.1    Hasegawa, E.2    Murai, T.3
  • 47
    • 0027486512 scopus 로고
    • Experimental Parkinson's disease in monkeys: Effect of ergot alkaloid derivative on lipid peroxidation in different brain areas
    • Marzatico, F., Café, C., Taborelli, M., and Benzi, G. (1993) Experimental Parkinson's disease in monkeys: effect of ergot alkaloid derivative on lipid peroxidation in different brain areas. Neurochem. Res. 18, 1101-1116
    • (1993) Neurochem. Res. , vol.18 , pp. 1101-1116
    • Marzatico, F.1    Café, C.2    Taborelli, M.3    Benzi, G.4
  • 49
    • 0017834660 scopus 로고
    • Lack of effect of bromocriptine on the activity of monoamine oxidase in rat brain
    • Burki, H. R. (1978) Lack of effect of bromocriptine on the activity of monoamine oxidase in rat brain. J. Pharm. Pharmacol. 30, 261-262
    • (1978) J. Pharm. Pharmacol. , vol.30 , pp. 261-262
    • Burki, H.R.1
  • 50
    • 0023793384 scopus 로고
    • The motor effects of bromocriptine - A review
    • Jackson, D. M., Jenkins, O. F., and Ross, S. B. (1988) The motor effects of bromocriptine - a review. Psychopharmacology 95, 433-446
    • (1988) Psychopharmacology , vol.95 , pp. 433-446
    • Jackson, D.M.1    Jenkins, O.F.2    Ross, S.B.3
  • 51
    • 0029005237 scopus 로고
    • Antipar-kinsonian therapies and brain mitochondrial complex I activity
    • Przedborski, S., Jackson-Lewis, V., and Falin, S. (1995) Antipar-kinsonian therapies and brain mitochondrial complex I activity. Movement Disorders 10, 312-317
    • (1995) Movement Disorders , vol.10 , pp. 312-317
    • Przedborski, S.1    Jackson-Lewis, V.2    Falin, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.