Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: Implications for Parkinson's disease

Free Radical Biology and Medicine

Volumn 41, Issue 9, 2006, Pages 1442-1448

  Chinta, Shankar J ^a   Andersen, Julie K ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

Glutathione depletion; Mitochondria; Parkinson's disease; Peroxynitrite; Thiol oxidation

Indexed keywords

BUTHIONINE SULFOXIMINE; DITHIOTHREITOL; ENZYME; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; MITOCHONDRIAL COMPLEX I; MITOCHONDRIAL PROTEIN; PEROXYNITRITE; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; DOPAMINERGIC ACTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; NITROSATION; PARKINSON DISEASE; PRIORITY JOURNAL;

BUTHIONINE SULFOXIMINE; CELL PROLIFERATION; CELLS, CULTURED; DITHIOTHREITOL; DOPAMINE; ELECTRON TRANSPORT COMPLEX I; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HUMANS; MITOCHONDRIA; NEURONS; NITRIC OXIDE; OXYGEN; PARKINSON DISEASE; PEROXYNITROUS ACID; S-NITROSOTHIOLS;

PARKINSONIA;

EID: 33749047253     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.08.002     Document Type: Article

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