Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion

Brain Research

Volumn 1051, Issue 1-2, 2005, Pages 25-34

  Sindhu, Kizhakke M ^a   Saravanan, Karuppagounder S ^a   Mohanakumar, Kochupurackal P ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Cognitive function; Complex I inhibitor; Elevated body swing test; Head position; Parkinsonism; Pesticide induced neurodegeneration; Progressive animal model; Stereotypic rotational behavior

Indexed keywords

APOMORPHINE; DEXAMPHETAMINE; ROTENONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROCHEMISTRY; FOREBRAIN; HEAD POSITION; MOTOR ACTIVITY; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; RAT; STEREOTAXIC SURGERY; SUBSTANTIA NIGRA;

ADRENERGIC AGENTS; AMPHETAMINE; ANIMALS; DOPAMINE; ELECTRON TRANSPORT COMPLEX I; ENZYME INHIBITORS; EXPLORATORY BEHAVIOR; FUNCTIONAL LATERALITY; MEDIAL FOREBRAIN BUNDLE; MICROINJECTIONS; MOTOR ACTIVITY; NEURONS; OXIDOPAMINE; PARKINSONIAN DISORDERS; POSTURE; RATS; ROTAROD PERFORMANCE TEST; ROTENONE; STEREOTYPED BEHAVIOR; SUBSTANTIA NIGRA;

EID: 22144431587     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.05.051     Document Type: Article

References (59)

1. Y. Agid, F. Javoy, and J. Glowinski Hyperactivity of remaining dopaminergic neurons after partial destruction of the nigro-striatal dopaminergic system in the rat Nat., New Biol. 245 1973 150 151
2. M. Alam, and W.J. Schmidt Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats Behav. Brain Res. 136 2002 317 324
3. M. Alam, and W.J. Schmidt l-DOPA reverses the hypo kinetic behaviour and rigidity in rotenone-treated rats Behav. Brain Res. 153 2004 439 446
4. M. Alam, A. Mayerhofer, and W.J. Schmidt The neurobehavioral changes induced by bilateral rotenone lesion in medial forebrain bundle of rats are reversed by l-DOPA Behav. Brain Res. 151 2004 117 124
5. R.L. Albin, A.B. Young, and J.B. Penney The functional anatomy of basal ganglia disorders Trends Neurosci. 12 1989 366 376
6. M.F. Beal Experimental models of Parkinson's disease Nat. Rev., Neurosci. 2 2001 325 332
7. R.M. Beckstead, G.F. Wooten, and J.M. Trugman Distribution of D1 and D2 dopamine receptors in the basal ganglia of the cat determined by quantitative autoradiography J. Comp. Neurol. 268 1988 131 145
8. M.J. Besson, A.M. Graybiel, and M.A. Nastuk [3H] SCH 23390 binding to D1 Dopamine receptors in the basal ganglia of the cat and primate: delineation of striosomal compartments and pallidal and nigral subdivisions Neuroscience 26 1988 101 119
9. R. Betarbet, T.B. Sherer, G. MacKenzie, M.G. Osuna, V.A. Pavanov, and T.J. Greenamyre Chronic systemic pesticide exposure reproduces features of Parkinson's disease Nat. Neurosci. 3 2000 1301 1306
10. C.V. Borlongan, and P.R. Sanberg Elevated body swing test: a new behavioural parameter for rats with 6-hydroxydopamine-induced hemiparkinsonism J. Neurosci. 15 1995 5372 5378
11. C.V. Borlongan, T.S. Randall, D.W. Cahill, and P.R. Sanberg Asymmetrical motor behavior in rats with unilateral striatal excitotoxic lesions as revealed by the EBST Brain Res. 676 1995 231 234
12. M.G. Boutelle, T. Zetterstrom, Q. Pei, L. Svensson, and M. Fillenz In vivo neurochemical effects of tail pinch J. Neurosci. Methods 34 1990 151 157
13. P.T. Bywood, and S.M. Johnson Mitochondrial complex inhibitors preferentially damage substantia nigra dopamine neurons in rat brain slices Exp. Neurol. 179 2003 47 59
14. E. Castaneda, I.Q. Whishaw, and T.E. Robinson Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size J. Neurosci. 10 1990 1847 1854
15. R.M. Clavier, S. Atmadja, and H.C. Fibiger Nigrothalamic projections in the rat as demonstrated by orthograde and retrograde tracing techniques Brain Res. Bull. 1 1976 379 384
16. H. Coulum, and S. Birman Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster J. Neurosci. 24 2004 10993 10998
17. M.S. Cousins, and J.D. Salamone Involvement of ventrolateral striatal dopamine in movement initiation and execution: a microdialysis and behavioral investigation Neuroscience 70 1996 849 859
18. M.S. Cousins, and J.D. Salamone Skilled motor deficits in rats induced by ventrolateral striatal dopamine depletions: behavioral and pharmacological characterization Brain Res. 732 1996 186 194
19. R.L. Faull, and W.R. Mehler The cells of origin of nigrotectal, nigrothalamic and nigrostriatal projections in the rat Neuroscience 3 1978 989 1002
20. S.E. File, N. Andrews, P.Y. Wu, A. Zharkovsky, and H. Zangrossi Jr. Modification of chlordiazepoxides's behavioural and neurochemical effects by handling and plus-maze experience Eur. J. Pharmacol. 218 1992 9 14
21. S.M. Fleming, C. Zhu, P.O. Fernagut, A. Mehta, C.D. DiCarlo, R.L. Seaman, and M.F. Chesselet Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone Exp. Neurol. 187 2004 418 429
22. J. Fornaguera, R.J. Carey, J.P. Huston, and R.K. Schwarting Behavioural asymmetries and recovery in rats with different degrees of unilateral striatal dopamine depletion Brain Res. 664 1994 178 188
23. P.O. Ghorayeb, L. Fernagut, L. Hervier, B. Labattu, B. Bioulac, and F. Tison A 'single toxin-double lesion' rat model of striatonigral degeneration by intrastriatal 1-methyl-4-phenylpyridinium ion injection: a motor behavioural analysis Neuroscience 115 2002 533 546
24. R. Haobam, K.M. Sindhu, G. Chandra, K.P. Mohanakumar, Swim-test as a function of motor impairment in MPTP model of Parkinson's disease: a comparative study in two mouse strains, Behav. Brain Res. (in press). doi:10.1016/j.bbr. 2005.04.011.
25. +)-analogs on the respiratory chain of bovine heart mitochondria Arch. Biochem. Biophys. 337 1997 69 74
26. Y. He, S.Z. Imam, Z. Dong, J. Jankovic, S.F. Ali, S.H. Appel, and W. Le Role of nitric oxide in rotenone-induced nigro-striatal injury J. Neurochem. 86 2003 1338 1345
27. F. Hefti, E. Melamed, and R.J. Wurtman Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterization Brain Res. 195 1980 123 137
28. 3H] spiroperidol binding and rotational behaviour in unilaterally 6-hydroxydopamine-lesioned rats Brain Res. 211 1981 285 292
29. J.M. Henderson, and S.H. Watson Convulsive and postural effects of lesioning the mid-substantia nigra pars reticulate in naïve and 6-hydroxydopamine lesioned rats Brain Res. Bull. 60 2003 179 185
30. J.M. Henderson, S.H. Watson, G.M. Halliday, and T.M. Heinemann Relationships between various behavioural abnormalities and nigrostriatal dopamine depletion in the unilateral 6-OHDA-lesioned rat Brain Res. 139 2003 105 113
31. J.L. Hudson, C.G. van Horne, I. Stormberg, S. Brock, J. Clayton, J. Masserano, B.J. Hoffer, and G.A. Gerhardt Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats Brain Res. 626 1993 167 174
32. D. Jasso-Lopez, and R. Tapia Neurotoxic effect of intranigral injection of 1-methyl-4-phenylpyridinium on GABA-containing neurons and its relation to circling behavior J. Neurochem. 64 1995 794 801
33. T.D. King, G.N. Bijur, and R.S. Jope Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3b and attenuated by lithium Brain Res. 919 2001 106 114
34. Y. Kitamura, M. Inden, A. Miyamura, J.I. Kakimura, T. Taniguchi, and S. Shimoham Possible involvement of both mitochondria- and endoplasmic reticulum-dependent caspase pathways in rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells Neurosci. Lett. 333 2002 25 28
35. J. Kondo, Y. Kitamura, M. Inden, and T. Taniguchi Hemiparkinsonian rat models: different sensitivity of dopaminergic neurotoxins Int. Congr. Ser. 1260 2004 281 285
36. S. Konitsiotis, E. Kafetzopoulos, D. Anastasopoulos, and P.J. Blanchet Opposite rotation induced by dopamine agonists in rats with unilateral lesions of the globus pallidus or substantia nigra Behav. Brain Res. 92 1998 77 83
37. N. Li, K. Ragheb, G. Lawler, J. Sturgis, B. Rajwa, J.A. Melendez, and J.P. Robinson Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production J. Biol. Chem. 278 2003 8516 8525
38. H. Matsuda, Y. Akechi, Y. Shimada, K. Terasawa, and H. Watanabe Relationship of the ipsilateral rotation in night period and striatal dopamine content reduction in unilateral nigrostriatal 6-OHDA lesioned rats Brain Res. 686 1995 111 114
39. E.A. Mazzio, R.R. Reams, and K.F. Soliman The role of oxidative stress, impaired glycolisis and mitochondrial respiratory redox failure in the cytotoxic effects of 6-hydroxydopamine in vitro Brain Res. 1004 2004 29 44
40. K.P. Mohanakumar, A. de Bartolomeis, R.M. Wu, K.J. Yeh, L.M. Sternberger, S.Y. Peng, D.L. Murphy, and C.C. Chiueh Ferrous-citrate complex and nigral degeneration: evidence for free-radical formation and lipid peroxidation Ann. N. Y. Acad. Sci. 738 1994 392 399
41. A.E. Moore, F. Cicchetti, J. Hennen, and O. Isacson Parkinsonian motor deficits are reflected by proportional A9/A10 dopamine neuron degeneration in the rat Exp. Neurol. 172 2001 363 376
42. D. Muralikrishnan, and K.P. Mohanakumar Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice FASEB. J. 12 1998 905 912
43. W.J.H. Nauta, and V.B. Domesick Afferent and efferent relationships of the basal ganglia D. Evered M. O'Connor Functions of the Basal Ganglia Ciba Found. Symp. vol. 107 1984 Pitman London 3 29
44. A.B. Norman, L.M. Wyatt, J.P. Hildebrand, M. Kolmonpunporn, C.A. Moody, M.N. Lehman, and P.R. Sanberg Sensitization of rotation behavior in rats with unilateral 6-hydroxydopamine or kainic acid-induced striatal lesions Pharmacol. Biochem. Behav. 37 1990 755 759
45. M. Palkovits, and M.J. Brownstein Microdissection of brain areas by punch technique A.C. Cuello Brain Microdissection Techniques 1983 John Wiley and Sons New York 1 36
46. G. Paxinos, and C. Watson The Rat Brain in Sterotaxic Coordinates 1998 Academic Press New York 1 120
47. D.A. Perese, J. Ulman, J. Viola, S.E. Ewing, and A. Bankiewicz 6-hydroxydopamine-induced selective parkinsonian rat model Brain Res. 494 1989 285 293
48. M. Pisa Regional specialization of motor functions in the rat striatum: implications for the treatment of parkinsonism Prog. Neuro-Psychopharmacol. Biol. Psychiatry 12 1988 217 224
49. S. Ponzoni, S.F. Guimaraes, A.E. Del Bel, and N. Garcia-Cairasco Behavioral effects of intra-nigral microinjections of manganese chloride: interaction with nitric oxide Prog. Neuro-Psychopharmacol. Biol. Psychiatry 24 2000 307 325
50. M. Roghani, G. Behzadi, and T. Baluchnejadmojarad Efficacy of elevated body swing test in the early model of Parkinson's disease in rat Physiol. Behav. 76 2002 507 510
51. K.S. Saravanan, K.M. Sindhu, and K.P. Mohanakumar Intranigral infusion of rotenone leads to oxidative stress and striatal dopaminergic toxicity in rats Ann. Neurosci. 8 2001 30
52. K.S. Saravanan, K.M. Sindhu, K.P. Mohanakumar, Intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease, Brain Res. (in press). doi:10.1016/j.brainres.2005.04. 051.
53. R.K. Schwarting, and J.P. Huston The unilateral 6-hydroxydopamine-lesion model in behavioural brain research: analysis of functional deficits, recovery and treatments Prog. Neurobiol. 50 1996 275 331
54. R.K. Schwarting, A.E. Bonatz, R.J. Carey, and J.P. Huston Relationships between indices of behavioural asymmetries and neurochemical changes following mesencephalic 6-hydroxydopamine injections Brain Res. 554 1991 46 55
55. A.A. Shah, and D. Treit Infusions of midazolam into the medial prefrontal cortex produce anxiolytic effects in the elevated Plus-Maze and shock-probe burying tests Brain Res. 996 2004 31 40
56. T.B. Sherer, R. Betarbet, K. Jin-Ho, and J.T. Greenamyre Selective microglial activation in the rat rotenone model of Parkinson's disease Neurosci. Lett. 341 2003 87 90
57. T.B. Sherer, K. Jin-Ho, R. Betarbet, and J.T. Greenamyre Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and α-synuclein aggregation Exp. Neurol. 179 2003 9 16
58. + J. Neural Transm. 74 1988 75 86
59. U. Ungerstedt, and G.W. Arbuthnott Quantitative recording of rotational behaviour in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system Brain Res. 24 1970 485 493