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Volumn 42, Issue 3, 2007, Pages 247-253

Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model

Author keywords

Free radical scavenger; Glutathione; Melatonin; Mitochondrial complex I; Parkinson's disease; Superoxide dismutase

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE; HYDROXYL RADICAL; MELATONIN; NEUROPROTECTIVE AGENT; ROTENONE; SCAVENGER; SUPEROXIDE DISMUTASE;

EID: 33847675291     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2006.00412.x     Document Type: Article
Times cited : (122)

References (68)
  • 1
    • 0019209714 scopus 로고
    • Pineal melatonin rhythm: Reduction in aging Syrian hamsters
    • REITER RJ, RICHARDSON BA, JOHNSON LY et al. Pineal melatonin rhythm: reduction in aging Syrian hamsters. Science 1980; 210:1372-1373.
    • (1980) Science , vol.210 , pp. 1372-1373
    • REITER, R.J.1    RICHARDSON, B.A.2    JOHNSON, L.Y.3
  • 2
    • 0022973346 scopus 로고
    • Human melatonin production decreases with age
    • SACK RL, LEWY AJ, ERB DL et al. Human melatonin production decreases with age. J Pineal Res 1986; 3:379-388.
    • (1986) J Pineal Res , vol.3 , pp. 379-388
    • SACK, R.L.1    LEWY, A.J.2    ERB, D.L.3
  • 3
    • 0027210003 scopus 로고
    • The melatonin rhythm: Both a clock and a calendar
    • REITER RJ. The melatonin rhythm: both a clock and a calendar. Experientia 1993; 49:654-664.
    • (1993) Experientia , vol.49 , pp. 654-664
    • REITER, R.J.1
  • 4
    • 0028018966 scopus 로고
    • Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses
    • REPPERT SM, WEAVER DR, EBISAWA T. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 1994; 13:1177-1185.
    • (1994) Neuron , vol.13 , pp. 1177-1185
    • REPPERT, S.M.1    WEAVER, D.R.2    EBISAWA, T.3
  • 5
    • 0033281970 scopus 로고    scopus 로고
    • Molecular pharmacology and function of melatonin receptor subtypes
    • DUBOCOVICH ML, MANSANA MI, BENLOUCIF S. Molecular pharmacology and function of melatonin receptor subtypes. Adv Exp Med Biol 1999; 460:181-190.
    • (1999) Adv Exp Med Biol , vol.460 , pp. 181-190
    • DUBOCOVICH, M.L.1    MANSANA, M.I.2    BENLOUCIF, S.3
  • 6
    • 0031845040 scopus 로고    scopus 로고
    • Oxidative damage in the central nervous system: Protection by melatonin
    • REITER RJ. Oxidative damage in the central nervous system: protection by melatonin. Prog Neurobiol 1998; 56:359-384.
    • (1998) Prog Neurobiol , vol.56 , pp. 359-384
    • REITER, R.J.1
  • 7
    • 0035754146 scopus 로고    scopus 로고
    • Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: A review of the evidence
    • REITER RJ, TAN DX, MANCHESTER LC et al. Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: a review of the evidence. Cell Biochem Biophys 2001; 34:237-256.
    • (2001) Cell Biochem Biophys , vol.34 , pp. 237-256
    • REITER, R.J.1    TAN, D.X.2    MANCHESTER, L.C.3
  • 8
    • 0036482282 scopus 로고    scopus 로고
    • Chemical and physical properties and potential mechanisms: Melatonin as a broad-spectrum antioxidant and free radical scavenger
    • TAN DX, REITER RJ, MANCHESTER LC et al. Chemical and physical properties and potential mechanisms: melatonin as a broad-spectrum antioxidant and free radical scavenger. Curr Top Med Chem 2002; 2:181-198.
    • (2002) Curr Top Med Chem , vol.2 , pp. 181-198
    • TAN, D.X.1    REITER, R.J.2    MANCHESTER, L.C.3
  • 9
    • 0029295723 scopus 로고
    • Melatonin protects neurons from singlet oxygen-induced apoptosis
    • CAGNOLI CM, ATABAY C, KHARLAMOVA E et al. Melatonin protects neurons from singlet oxygen-induced apoptosis. J Pineal Res 1995; 18:222-226.
    • (1995) J Pineal Res , vol.18 , pp. 222-226
    • CAGNOLI, C.M.1    ATABAY, C.2    KHARLAMOVA, E.3
  • 10
    • 0002979059 scopus 로고
    • Melatonin: A potent, endogenous hydroxyl radical scavenger
    • TAN DX, CHEN LD, POEGGELER B et al. Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr J 1993; 1:57-60.
    • (1993) Endocr J , vol.1 , pp. 57-60
    • TAN, D.X.1    CHEN, L.D.2    POEGGELER, B.3
  • 11
    • 0028137186 scopus 로고
    • Melatonin: A peroxyl radical scavenger more effective than vitamin E
    • PIERI C, MARRA M, MORONI F. Melatonin: a peroxyl radical scavenger more effective than vitamin E. Life Sci 1994; 55:271-276.
    • (1994) Life Sci , vol.55 , pp. 271-276
    • PIERI, C.1    MARRA, M.2    MORONI, F.3
  • 12
    • 1642440103 scopus 로고    scopus 로고
    • THOMAS B, MOHANAKUMAR KP. Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the mouse nigrostriatum. J Pineal Res 2004; 36:25-32.
    • THOMAS B, MOHANAKUMAR KP. Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the mouse nigrostriatum. J Pineal Res 2004; 36:25-32.
  • 13
    • 0028178826 scopus 로고
    • Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole
    • TAN DX, REITER RJ, CHEN LD et al. Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. Carcinogenesis 1994; 15:215-218.
    • (1994) Carcinogenesis , vol.15 , pp. 215-218
    • TAN, D.X.1    REITER, R.J.2    CHEN, L.D.3
  • 14
    • 0028955117 scopus 로고
    • Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity
    • GUISTI P, GUSELLA M, LIPARTITI M et al. Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity. Exp Neurol 1995; 131:39-46.
    • (1995) Exp Neurol , vol.131 , pp. 39-46
    • GUISTI, P.1    GUSELLA, M.2    LIPARTITI, M.3
  • 15
    • 0030218902 scopus 로고    scopus 로고
    • Protective effect of melatonin against hippocampal DNA damage induced by intraperitoneal administration of kainate to rats
    • UZ T, GUISTI P, FRANCESHINI D et al. Protective effect of melatonin against hippocampal DNA damage induced by intraperitoneal administration of kainate to rats. Neuroscience 1996; 73:631-636.
    • (1996) Neuroscience , vol.73 , pp. 631-636
    • UZ, T.1    GUISTI, P.2    FRANCESHINI, D.3
  • 16
    • 0030929407 scopus 로고    scopus 로고
    • Melatonin protects against lipid peroxidation induced by delta-aminolevulinic acid in rat cerebellum, cortex and hippocampus
    • CARNEIRO RC, REITER RJ. Melatonin protects against lipid peroxidation induced by delta-aminolevulinic acid in rat cerebellum, cortex and hippocampus. Neuroscience 1998; 82:293-298.
    • (1998) Neuroscience , vol.82 , pp. 293-298
    • CARNEIRO, R.C.1    REITER, R.J.2
  • 17
    • 0033399823 scopus 로고    scopus 로고
    • Melatonin reduces quinolinic acid-induced lipid peroxidation in rat brain homogenate
    • SOUTHGATE G, DAYA S. Melatonin reduces quinolinic acid-induced lipid peroxidation in rat brain homogenate. Metab Brain Dis 1999; 14:165-171.
    • (1999) Metab Brain Dis , vol.14 , pp. 165-171
    • SOUTHGATE, G.1    DAYA, S.2
  • 18
    • 25144447579 scopus 로고    scopus 로고
    • Reactions of the melatonin metabolite AMK (N1-acetyl-5-methoxykynuramine) with reactive nitrogen species: Formation of novel compounds, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK
    • GUENTHER AL, SCHMIDT SI, LAATSCH H et al. Reactions of the melatonin metabolite AMK (N1-acetyl-5-methoxykynuramine) with reactive nitrogen species: formation of novel compounds, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK. J Pineal Res 2005; 39:251-260.
    • (2005) J Pineal Res , vol.39 , pp. 251-260
    • GUENTHER, A.L.1    SCHMIDT, S.I.2    LAATSCH, H.3
  • 19
    • 14344265259 scopus 로고    scopus 로고
    • Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol
    • ONUKI J, ALMEIDA EA, MEDEIROS MH et al. Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol. J Pineal Res 2005; 38:107-115.
    • (2005) J Pineal Res , vol.38 , pp. 107-115
    • ONUKI, J.1    ALMEIDA, E.A.2    MEDEIROS, M.H.3
  • 20
    • 0015182655 scopus 로고
    • Adipsia and aphagia after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system
    • UNGERSTEDT U. Adipsia and aphagia after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system. Acta Physiol Scand Suppl 1971; 367:95-122.
    • (1971) Acta Physiol Scand Suppl , vol.367 , pp. 95-122
    • UNGERSTEDT, U.1
  • 21
    • 0021245433 scopus 로고    scopus 로고
    • BURNS RS, MARKEY SP, PHILLIPS JM et al. The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the monkey and man. Can J Neurol Sci 1984; 11:166-168.
    • BURNS RS, MARKEY SP, PHILLIPS JM et al. The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the monkey and man. Can J Neurol Sci 1984; 11:166-168.
  • 22
    • 0028775839 scopus 로고
    • Ferrous-citrate complex and nigral degeneration: Evidence for free radical formation and lipid peroxidation
    • MOHANAKUMAR KP, DE BARTOLOMEIS A, WU RM et al. Ferrous-citrate complex and nigral degeneration: Evidence for free radical formation and lipid peroxidation. Ann NY Acad Sci 1994; 738:392-399.
    • (1994) Ann NY Acad Sci , vol.738 , pp. 392-399
    • MOHANAKUMAR, K.P.1    DE BARTOLOMEIS, A.2    WU, R.M.3
  • 23
    • 0033681149 scopus 로고    scopus 로고
    • BETARBET R, SHERER TB, MACKENZIE G et al. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 2000; 12:1301-vv1306.
    • BETARBET R, SHERER TB, MACKENZIE G et al. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 2000; 12:1301-vv1306.
  • 24
    • 23044486663 scopus 로고    scopus 로고
    • Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease
    • SARAVANAN KS, SINDHU KM, MOHANAKUMAR KP. Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease. Brain Res 2005; 1049:147-155.
    • (2005) Brain Res , vol.1049 , pp. 147-155
    • SARAVANAN, K.S.1    SINDHU, K.M.2    MOHANAKUMAR, K.P.3
  • 25
    • 33644903828 scopus 로고    scopus 로고
    • Acute intranigral homocysteine administration produces stereotypic behavioral changes and striatal dopamine depletion in Sprague-Dawley rats
    • CHANDRA G, GANGOPADHYAY PK, Senthil Kumar KS et al. Acute intranigral homocysteine administration produces stereotypic behavioral changes and striatal dopamine depletion in Sprague-Dawley rats. Brain Res 2006; 1075:81-92.
    • (2006) Brain Res , vol.1075 , pp. 81-92
    • CHANDRA, G.1    GANGOPADHYAY, P.K.2    Senthil Kumar, K.S.3
  • 26
    • 0027344407 scopus 로고
    • Role of dopamine autoxidation, hydroxyl radical generation, and calcium overload in underlying mechanisms involved in MPTP-induced parkinsonism
    • CHIUEH CC, MIYAKE H, PENG MT. Role of dopamine autoxidation, hydroxyl radical generation, and calcium overload in underlying mechanisms involved in MPTP-induced parkinsonism. Adv Neurol 1993; 60:251-258.
    • (1993) Adv Neurol , vol.60 , pp. 251-258
    • CHIUEH, C.C.1    MIYAKE, H.2    PENG, M.T.3
  • 27
  • 28
    • 0037378897 scopus 로고    scopus 로고
    • Apoptosis in Parkinson's disease: Signals for neuronal degradation
    • TATTON WG, CHALMERS-REDMAN R, BROWN D et al. Apoptosis in Parkinson's disease: signals for neuronal degradation. Ann Neurol 2003; 53:S61-S70.
    • (2003) Ann Neurol , vol.53
    • TATTON, W.G.1    CHALMERS-REDMAN, R.2    BROWN, D.3
  • 29
    • 0024330311 scopus 로고
    • Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease
    • MIZUNO Y, OHTA S, TANAKA M et al. Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease. Biochem Biophys Res Commun 1989; 163:1450-1455.
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 1450-1455
    • MIZUNO, Y.1    OHTA, S.2    TANAKA, M.3
  • 30
    • 0000666289 scopus 로고    scopus 로고
    • Neurochemical mechanisms underlying neuroprotective actions of bromocriptine, salicylate, D- and L-deprenyl in neurodegeneration caused by MPTP
    • Collins MA, Storch A, eds. Kluwer Academic/Plenum, New York
    • MOHANAKUMAR KP, MURALIKRISHNAN D. Neurochemical mechanisms underlying neuroprotective actions of bromocriptine, salicylate, D- and L-deprenyl in neurodegeneration caused by MPTP. In: Neurotoxic Factors in Parkinson's Disease and Related Disorders. Collins MA, Storch A, eds. Kluwer Academic/Plenum, New York, 2000; pp. 289-293.
    • (2000) Neurotoxic Factors in Parkinson's Disease and Related Disorders , pp. 289-293
    • MOHANAKUMAR, K.P.1    MURALIKRISHNAN, D.2
  • 31
    • 26444515945 scopus 로고    scopus 로고
    • Pramipexole in the treatment of Parkinson's disease: New developments
    • MOLLER JC, OERTEL WH. Pramipexole in the treatment of Parkinson's disease: new developments. Exp Rev Neurother 2005; 5:581-586.
    • (2005) Exp Rev Neurother , vol.5 , pp. 581-586
    • MOLLER, J.C.1    OERTEL, W.H.2
  • 32
    • 33646527553 scopus 로고    scopus 로고
    • SARAVANAN KS, SINDHU KM, SENTHILKUMAR KS et al. L-Deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats. Neurochem Int 2006; 49:28-40.
    • SARAVANAN KS, SINDHU KM, SENTHILKUMAR KS et al. L-Deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats. Neurochem Int 2006; 49:28-40.
  • 33
    • 0035170284 scopus 로고    scopus 로고
    • Melatonin protects against 6-OHDA-induced neurotoxicity in rats: A role for mitochondrial complex I activity
    • DABBENI-SALA F, DI SANTO S, FRANCESCHINI D et al. Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity. FASEB J 2001; 15:164-170.
    • (2001) FASEB J , vol.15 , pp. 164-170
    • DABBENI-SALA, F.1    DI SANTO, S.2    FRANCESCHINI, D.3
  • 34
    • 0037067791 scopus 로고    scopus 로고
    • Protective effect of melatonin in a chronic experimental model of Parkinson's disease
    • ANTOLIN I, MAYO JC, SAINZ RM et al. Protective effect of melatonin in a chronic experimental model of Parkinson's disease. Brain Res 2002; 943:163-173.
    • (2002) Brain Res , vol.943 , pp. 163-173
    • ANTOLIN, I.1    MAYO, J.C.2    SAINZ, R.M.3
  • 35
    • 0030606143 scopus 로고    scopus 로고
    • Melatonin is protective against MPTP-induced striatal and hippocampal lesions
    • ACUNA-CASTROVIEJO D, COTO-MONTES A, GAIA MONTI M et al. Melatonin is protective against MPTP-induced striatal and hippocampal lesions. Life Sci 1997; 60:23-29.
    • (1997) Life Sci , vol.60 , pp. 23-29
    • ACUNA-CASTROVIEJO, D.1    COTO-MONTES, A.2    GAIA MONTI, M.3
  • 36
    • 0031839674 scopus 로고    scopus 로고
    • ITZHAK Y, MARTIN JL, BLACK M. Effect of melatonin on methamphetamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- induced dopaminergic neurotoxicity and methamphetamine-induced behavioral sensitization. Neuropharmacology 1998; 37:781-791.
    • ITZHAK Y, MARTIN JL, BLACK M. Effect of melatonin on methamphetamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- induced dopaminergic neurotoxicity and methamphetamine-induced behavioral sensitization. Neuropharmacology 1998; 37:781-791.
  • 37
    • 0035824271 scopus 로고    scopus 로고
    • Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathway
    • MORGAN WW, NELSON JF. Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathway. Brain Res 2001; 921:115-121.
    • (2001) Brain Res , vol.921 , pp. 115-121
    • MORGAN, W.W.1    NELSON, J.F.2
  • 38
    • 0037405378 scopus 로고    scopus 로고
    • Synergistic effects of melatonin and deprenyl against MPTP-induced mitochondrial damage and DA depletion
    • KHALDY H, ESCAMES G, LEON J et al. Synergistic effects of melatonin and deprenyl against MPTP-induced mitochondrial damage and DA depletion. Neurobiol Aging 2003; 24:491-500.
    • (2003) Neurobiol Aging , vol.24 , pp. 491-500
    • KHALDY, H.1    ESCAMES, G.2    LEON, J.3
  • 39
    • 22144431587 scopus 로고    scopus 로고
    • Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion
    • SINDHU KM, SARAVANAN KS, MOHANAKUMAR KP. Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion. Brain Res 2005; 1051:25-34.
    • (2005) Brain Res , vol.1051 , pp. 25-34
    • SINDHU, K.M.1    SARAVANAN, K.S.2    MOHANAKUMAR, K.P.3
  • 40
    • 10044292870 scopus 로고    scopus 로고
    • Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster
    • COULOM H, BIRMAN S. Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster. J Neurosci 2004; 24:10993-10998.
    • (2004) J Neurosci , vol.24 , pp. 10993-10998
    • COULOM, H.1    BIRMAN, S.2
  • 41
    • 24144483470 scopus 로고    scopus 로고
    • 2+-induced mitochondrial oxidative stress and PC12 cell death
    • 2+-induced mitochondrial oxidative stress and PC12 cell death. Antioxid Redox Signal 2005; 9:1110-1116.
    • (2005) Antioxid Redox Signal , vol.9 , pp. 1110-1116
    • SOUSA, S.C.1    CASTILHO, R.F.2
  • 43
    • 0013893023 scopus 로고
    • Fluorimetric assay for glutathione
    • COHN VH, LYLE A. Fluorimetric assay for glutathione. Anal Biochem 1966; 14:434-440.
    • (1966) Anal Biochem , vol.14 , pp. 434-440
    • COHN, V.H.1    LYLE, A.2
  • 44
    • 0016272750 scopus 로고
    • Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • MARKLUND S, MARKLUND G. Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974; 47:469-474.
    • (1974) Eur J Biochem , vol.47 , pp. 469-474
    • MARKLUND, S.1    MARKLUND, G.2
  • 46
    • 0028245211 scopus 로고
    • Melatonin is a free radical scavenger implications for ageing and age related diseases
    • REITER RJ, TAN DX, POEGGELER B et al. Melatonin is a free radical scavenger implications for ageing and age related diseases. Ann N Y Acad Sci 1994; 719:1-12.
    • (1994) Ann N Y Acad Sci , vol.719 , pp. 1-12
    • REITER, R.J.1    TAN, D.X.2    POEGGELER, B.3
  • 47
    • 0029105296 scopus 로고
    • A review of the evidence supporting melatonin's role as an antioxidant
    • REITER RJ, MELCHIORRI D, SEWERYNEK E et al. A review of the evidence supporting melatonin's role as an antioxidant. J Pineal Res 1995; 18:1-11.
    • (1995) J Pineal Res , vol.18 , pp. 1-11
    • REITER, R.J.1    MELCHIORRI, D.2    SEWERYNEK, E.3
  • 48
    • 0033402469 scopus 로고    scopus 로고
    • Excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin
    • SKAPER SD, FLOREANI M, CECCON M et al. Excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin. Ann N Y Acad Sci 1999; 890:107-118.
    • (1999) Ann N Y Acad Sci , vol.890 , pp. 107-118
    • SKAPER, S.D.1    FLOREANI, M.2    CECCON, M.3
  • 49
    • 12244293596 scopus 로고    scopus 로고
    • Comparative effects of melatonin, L-deprenyl, Trolox and ascorbate in the suppression of hydroxyl formation during dopamine auto-oxidation in vitro
    • KHALDY H, ESCAMES G, LEÓN J. Comparative effects of melatonin, L-deprenyl, Trolox and ascorbate in the suppression of hydroxyl formation during dopamine auto-oxidation in vitro. J Pineal Res 2000; 24:215-218.
    • (2000) J Pineal Res , vol.24 , pp. 215-218
    • KHALDY, H.1    ESCAMES, G.2    LEÓN, J.3
  • 50
    • 0035341492 scopus 로고    scopus 로고
    • Parkinson's disease, pesticides and mitochondrial dysfunction
    • JENNER P. Parkinson's disease, pesticides and mitochondrial dysfunction. Trends Neurosci 2001; 24:245-247.
    • (2001) Trends Neurosci , vol.24 , pp. 245-247
    • JENNER, P.1
  • 51
    • 0027185713 scopus 로고
    • Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease
    • JENNER P. Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease. Acta Neurol Scand Suppl 1993; 146:6-13.
    • (1993) Acta Neurol Scand Suppl , vol.146 , pp. 6-13
    • JENNER, P.1
  • 53
    • 0031801548 scopus 로고    scopus 로고
    • MURALIKRISHNAN D, MOHANAKUMAR KP. Neuroprotection by bromocryptine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice. Faseb J 1998; 12:905-912.
    • MURALIKRISHNAN D, MOHANAKUMAR KP. Neuroprotection by bromocryptine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice. Faseb J 1998; 12:905-912.
  • 54
    • 0034640430 scopus 로고    scopus 로고
    • MOHANAKUMAR KP, MURALIKRISHNAN D, THOMAS B. Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity. Brain Res 2000; 864:281-290.
    • MOHANAKUMAR KP, MURALIKRISHNAN D, THOMAS B. Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity. Brain Res 2000; 864:281-290.
  • 55
    • 0041920820 scopus 로고    scopus 로고
    • MURALIKRISHNAN D, SAMANTARAY S, MOHANAKUMAR KP. D-deprenyl protects nigrostriatal neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity. Synapse 2003; 50:7-13.
    • MURALIKRISHNAN D, SAMANTARAY S, MOHANAKUMAR KP. D-deprenyl protects nigrostriatal neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity. Synapse 2003; 50:7-13.
  • 56
    • 0029082155 scopus 로고
    • Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions
    • MELCHIORRI D, REITER RJ, SEWERYNEK E et al. Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions. Faseb J 1995; 9:1205-1210.
    • (1995) Faseb J , vol.9 , pp. 1205-1210
    • MELCHIORRI, D.1    REITER, R.J.2    SEWERYNEK, E.3
  • 57
    • 0029348970 scopus 로고
    • 2-induced lipid peroxidation in homogenates of different rat brain regions
    • 2-induced lipid peroxidation in homogenates of different rat brain regions. J Pineal Res 1995; 1:51-56.
    • (1995) J Pineal Res , vol.1 , pp. 51-56
    • SEWERYNEK, E.1    MELCHIORRI, D.2    ORTIZ, G.G.3
  • 58
    • 0028075410 scopus 로고
    • Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
    • SIAN J, DEXTER DT, LEES AJ et al. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol 1994; 36:348-355.
    • (1994) Ann Neurol , vol.36 , pp. 348-355
    • SIAN, J.1    DEXTER, D.T.2    LEES, A.J.3
  • 60
    • 0030693112 scopus 로고    scopus 로고
    • Melatonin maintains glutathione homeostasis in kainic acid-exposed rat brain tissues
    • FLOREANI M, SKAPER SD, FACCI L et al. Melatonin maintains glutathione homeostasis in kainic acid-exposed rat brain tissues. Faseb J 1997; 11:1309-1315.
    • (1997) Faseb J , vol.11 , pp. 1309-1315
    • FLOREANI, M.1    SKAPER, S.D.2    FACCI, L.3
  • 61
    • 0032878234 scopus 로고    scopus 로고
    • Melatonin induces gammaglutymlcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells
    • URATA Y, HONMA S, GOTO S et al. Melatonin induces gammaglutymlcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells. Free Radic Biol Med 1999; 27:838-847.
    • (1999) Free Radic Biol Med , vol.27 , pp. 838-847
    • URATA, Y.1    HONMA, S.2    GOTO, S.3
  • 62
    • 33645121542 scopus 로고    scopus 로고
    • Melatonin attenuates diabetes-induced oxidative stress in rabbits
    • WINIARSKA K, FRACZYK T, MALINSKA D et al. Melatonin attenuates diabetes-induced oxidative stress in rabbits. J Pineal Res 2006; 40:160-176.
    • (2006) J Pineal Res , vol.40 , pp. 160-176
    • WINIARSKA, K.1    FRACZYK, T.2    MALINSKA, D.3
  • 63
    • 0033768749 scopus 로고    scopus 로고
    • Actions of melatonin in the reduction of oxidative stress: A review
    • REITER RJ, TAN DX, OSUNA C et al. Actions of melatonin in the reduction of oxidative stress: a review. J Biomed Sci 2000; 7:444-458.
    • (2000) J Biomed Sci , vol.7 , pp. 444-458
    • REITER, R.J.1    TAN, D.X.2    OSUNA, C.3
  • 64
    • 0033835378 scopus 로고    scopus 로고
    • Effect of pineal indoles on activities of the antioxidant defense enzymes superoxide dismutase, catalase, and glutathione reductase, and levels of reduced and oxidized glutathione in rat tissues
    • LIU F, NG TB. Effect of pineal indoles on activities of the antioxidant defense enzymes superoxide dismutase, catalase, and glutathione reductase, and levels of reduced and oxidized glutathione in rat tissues. Biochem Cell Biol 2000; 78:447-453.
    • (2000) Biochem Cell Biol , vol.78 , pp. 447-453
    • LIU, F.1    NG, T.B.2
  • 65
    • 0031967974 scopus 로고    scopus 로고
    • Melatonin increases gene expression for antioxidant enzymes in rat brain cortex
    • KOTLER M, RODRIGUEZ C, SAINZ RM et al. Melatonin increases gene expression for antioxidant enzymes in rat brain cortex. J Pineal Res 1998; 24:83-89.
    • (1998) J Pineal Res , vol.24 , pp. 83-89
    • KOTLER, M.1    RODRIGUEZ, C.2    SAINZ, R.M.3
  • 66
    • 0036809371 scopus 로고    scopus 로고
    • Melatonin regulation of antioxidant enzyme gene expression
    • MAYO JC, SAINZ RM, ANTOLI I et al. Melatonin regulation of antioxidant enzyme gene expression. Cell Mol Life Sci 2002; 59:1706-1713.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 1706-1713
    • MAYO, J.C.1    SAINZ, R.M.2    ANTOLI, I.3
  • 67
    • 0031451552 scopus 로고    scopus 로고
    • Antioxidative effect of melatonin in rat brain oxidative stress induced by adriamycin
    • MONTILLA P, TUNEZ I, MUNOZ MC et al. Antioxidative effect of melatonin in rat brain oxidative stress induced by adriamycin. Rev Esp Fisiol 1997; 53:301-305.
    • (1997) Rev Esp Fisiol , vol.53 , pp. 301-305
    • MONTILLA, P.1    TUNEZ, I.2    MUNOZ, M.C.3
  • 68
    • 0031981649 scopus 로고    scopus 로고
    • Melatonin prevents apoptosis induced by 6-hydroxydopamine in neuronal cells: Implications for Parkinson's disease
    • MAYO JC, SAINZ RM, URIA H et al. Melatonin prevents apoptosis induced by 6-hydroxydopamine in neuronal cells: implications for Parkinson's disease. J Pineal Res 1998; 24:179-192.
    • (1998) J Pineal Res , vol.24 , pp. 179-192
    • MAYO, J.C.1    SAINZ, R.M.2    URIA, H.3


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