-
2
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
discussion S-8
-
Jenner P. Oxidative stress in Parkinson's disease. Ann Neurol. 2003, 53:S26-36. discussion S-8
-
(2003)
Ann Neurol.
, vol.53
-
-
Jenner, P.1
-
3
-
-
21844441151
-
Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease
-
Liu J, Ames BN. Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease. Nutr Neurosci. 2005, 8:67-89.
-
(2005)
Nutr Neurosci.
, vol.8
, pp. 67-89
-
-
Liu, J.1
Ames, B.N.2
-
4
-
-
36949012725
-
The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview
-
Liu J. The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview. Neurochem Res. 2008, 33:194-203.
-
(2008)
Neurochem Res.
, vol.33
, pp. 194-203
-
-
Liu, J.1
-
5
-
-
0037379314
-
Bioenergetic approaches for neuroprotection in Parkinson's disease
-
discussion S-8
-
Beal MF. Bioenergetic approaches for neuroprotection in Parkinson's disease. Ann Neurol. 2003, 53:S39-47. discussion S-8
-
(2003)
Ann Neurol.
, vol.53
-
-
Beal, M.F.1
-
6
-
-
0031594295
-
Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice
-
Beal MF, Matthews RT, Tieleman A. Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice. Brain Res. 1998, 783:109-14.
-
(1998)
Brain Res.
, vol.783
, pp. 109-114
-
-
Beal, M.F.1
Matthews, R.T.2
Tieleman, A.3
-
7
-
-
0036771852
-
Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline
-
Shults CW, Oakes D, Kieburtz K. Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline. Arch Neurol. 2002, 59:1541-50.
-
(2002)
Arch Neurol.
, vol.59
, pp. 1541-1550
-
-
Shults, C.W.1
Oakes, D.2
Kieburtz, K.3
-
8
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell. 2006, 127:397-408.
-
(2006)
Cell.
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
-
9
-
-
33749042331
-
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
-
Cui L, Jeong H, Borovecki F. Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell. 2006, 127:59-69.
-
(2006)
Cell.
, vol.127
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
-
11
-
-
1542723493
-
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
-
Suh JH, Shenvi SV, Dixon BM. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad Sci USA. 2004, 101:3381-6.
-
(2004)
Proc Natl Acad Sci USA.
, vol.101
, pp. 3381-3386
-
-
Suh, J.H.1
Shenvi, S.V.2
Dixon, B.M.3
-
12
-
-
0036240776
-
Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites
-
Liu J, Atamna H, Kuratsune H. Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. Ann New York Acad Sci. 2002, 959:133-66.
-
(2002)
Ann New York Acad Sci.
, vol.959
, pp. 133-166
-
-
Liu, J.1
Atamna, H.2
Kuratsune, H.3
-
13
-
-
0038433337
-
Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells
-
Mazzio E, Yoon KJ, Soliman KF. Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells. Biochem Pharmaco. 2003, 66:297-306.
-
(2003)
Biochem Pharmaco.
, vol.66
, pp. 297-306
-
-
Mazzio, E.1
Yoon, K.J.2
Soliman, K.F.3
-
15
-
-
0036778280
-
Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy
-
Bharat S, Cochran BC, Hsu M. Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy. Neurotoxicology. 2002, 23:479-86.
-
(2002)
Neurotoxicology.
, vol.23
, pp. 479-486
-
-
Bharat, S.1
Cochran, B.C.2
Hsu, M.3
-
16
-
-
34347369328
-
Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid
-
Karunakaran S, Diwakar L, Saeed U. Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid. FASEB J. 2007, 21:2226-36.
-
(2007)
FASEB J.
, vol.21
, pp. 2226-2236
-
-
Karunakaran, S.1
Diwakar, L.2
Saeed, U.3
-
17
-
-
0037104723
-
An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
-
Sherer TB, Betarbet R, Stout AK. An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. J Neurosci. 2002, 22:7006-15.
-
(2002)
J Neurosci.
, vol.22
, pp. 7006-7015
-
-
Sherer, T.B.1
Betarbet, R.2
Stout, A.K.3
-
18
-
-
34147196228
-
Spectrophotometric assay for complex I of the respiratory chain in tissue samples and cultured fibroblasts
-
Janssen AJ, Trijbels FJ, Sengers RC. Spectrophotometric assay for complex I of the respiratory chain in tissue samples and cultured fibroblasts. Clin Chem. 2007, 53:729-34.
-
(2007)
Clin Chem.
, vol.53
, pp. 729-734
-
-
Janssen, A.J.1
Trijbels, F.J.2
Sengers, R.C.3
-
19
-
-
0025806764
-
Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1
-
Smiley ST, Reers M, Mottola-Hartshorn C. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci USA. 1991, 88:3671-5.
-
(1991)
Proc Natl Acad Sci USA.
, vol.88
, pp. 3671-3675
-
-
Smiley, S.T.1
Reers, M.2
Mottola-Hartshorn, C.3
-
20
-
-
18644370269
-
A newly established neuronal rho-0 cell line highly susceptible to oxidative stress accumulates iron and other metals. Relevance to the origin of metal ion deposits in brains with neurodegenerative disorders
-
Fukuyama R, Nakayama A, Nakase T. A newly established neuronal rho-0 cell line highly susceptible to oxidative stress accumulates iron and other metals. Relevance to the origin of metal ion deposits in brains with neurodegenerative disorders. J Biol Chem. 2002, 277:41455-62.
-
(2002)
J Biol Chem.
, vol.277
, pp. 41455-41462
-
-
Fukuyama, R.1
Nakayama, A.2
Nakase, T.3
-
21
-
-
0027249757
-
Evaluation of 2′,7′-dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cells
-
Royall JA, Ischiropoulos H. Evaluation of 2′,7′-dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cells. Arch Biochem Biophys. 1993, 302:348-55.
-
(1993)
Arch Biochem Biophys.
, vol.302
, pp. 348-355
-
-
Royall, J.A.1
Ischiropoulos, H.2
-
22
-
-
20944451305
-
Heterogeneity in DNA damage using the comet assay
-
Olive PL, Durand RE. Heterogeneity in DNA damage using the comet assay. Cytometry A. 2005, 66:1-8.
-
(2005)
Cytometry A.
, vol.66
, pp. 1-8
-
-
Olive, P.L.1
Durand, R.E.2
-
23
-
-
33644778845
-
Parkin enhances mitochondrial biogenesis in proliferating cells
-
Kuroda Y, Mitsui T, Kunishige M. Parkin enhances mitochondrial biogenesis in proliferating cells. Hum Mol Genet. 2006, 15:883-95.
-
(2006)
Hum Mol Genet.
, vol.15
, pp. 883-895
-
-
Kuroda, Y.1
Mitsui, T.2
Kunishige, M.3
-
24
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
-
Wallace DC. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet. 2005, 39:359-407.
-
(2005)
Annu Rev Genet.
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
25
-
-
0036829946
-
Neuroprotective and neurorestorative strategies for Parkinson's disease
-
Dawson TM, Dawson VL. Neuroprotective and neurorestorative strategies for Parkinson's disease. Nat Neurosci. 2002, 5:1058-61.
-
(2002)
Nat Neurosci.
, vol.5
, pp. 1058-1061
-
-
Dawson, T.M.1
Dawson, V.L.2
-
26
-
-
20544431978
-
Neuroprotective therapy in Parkinson's disease and motor complications: a search for a pathogenesis-targeted, disease-modifying strategy
-
Olanow CW, Jankovic J. Neuroprotective therapy in Parkinson's disease and motor complications: a search for a pathogenesis-targeted, disease-modifying strategy. Mov Disord. 2005, 20:S3-10.
-
(2005)
Mov Disord.
, vol.20
-
-
Olanow, C.W.1
Jankovic, J.2
-
27
-
-
0345601861
-
Can we prevent Parkinson's and Alzheimer's disease
-
Kedar NP. Can we prevent Parkinson's and Alzheimer's disease. J Postgrad Med. 2003, 49:236-45.
-
(2003)
J Postgrad Med.
, vol.49
, pp. 236-245
-
-
Kedar, N.P.1
-
28
-
-
33750710080
-
Protein oxidation and aging
-
Stadtman ER. Protein oxidation and aging. Free Radic Res. 2006, 40:1250-8.
-
(2006)
Free Radic Res.
, vol.40
, pp. 1250-1258
-
-
Stadtman, E.R.1
-
29
-
-
0037133319
-
Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha -lipoic acid
-
Liu J, Killilea DW, Ames BN. Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha -lipoic acid. Proc Natl Acad Sci USA. 2002, 99:1876-81.
-
(2002)
Proc Natl Acad Sci USA.
, vol.99
, pp. 1876-1881
-
-
Liu, J.1
Killilea, D.W.2
Ames, B.N.3
-
30
-
-
0037133283
-
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha-lipoic acid
-
Liu J, Head E, Gharib AM. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha-lipoic acid. Proc Natl Acad Sci USA. 2002, 99:2356-61.
-
(2002)
Proc Natl Acad Sci USA.
, vol.99
, pp. 2356-2361
-
-
Liu, J.1
Head, E.2
Gharib, A.M.3
-
31
-
-
0037133304
-
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress
-
Hagen TM, Liu J, Lykkesfeldt J. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci USA. 2002, 99:1870-5.
-
(2002)
Proc Natl Acad Sci USA.
, vol.99
, pp. 1870-1875
-
-
Hagen, T.M.1
Liu, J.2
Lykkesfeldt, J.3
-
32
-
-
0032497504
-
Parkinson's disease. First of two parts
-
Lang AE, Lozano AM. Parkinson's disease. First of two parts. N Engl J Med. 1998, 339:1044-53.
-
(1998)
N Engl J Med.
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
33
-
-
0032531924
-
Parkinson's disease. Second of two parts
-
Lang AE, Lozano AM. Parkinson's disease. Second of two parts. N Engl J Med. 1998, 339:1130-43.
-
(1998)
N Engl J Med.
, vol.339
, pp. 1130-1143
-
-
Lang, A.E.1
Lozano, A.M.2
-
34
-
-
0032522873
-
Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies
-
Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA. 1998, 279:1200-5.
-
(1998)
JAMA.
, vol.279
, pp. 1200-1205
-
-
Lazarou, J.1
Pomeranz, B.H.2
Corey, P.N.3
|