-
1
-
-
77953642472
-
Glioblastoma therapy: Going beyond Hercules Columns
-
Mangiola A, Anile C, Pompucci A, Capone G, Rigante L, De Bonis P (2010) Glioblastoma therapy: going beyond Hercules Columns. Expert Rev Neurother 10(4):507-514
-
(2010)
Expert Rev Neurother
, vol.10
, Issue.4
, pp. 507-514
-
-
Mangiola, A.1
Anile, C.2
Pompucci, A.3
Capone, G.4
Rigante, L.5
De Bonis, P.6
-
2
-
-
77952555038
-
Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma
-
Van Meir EG, Hadjipanayis CG, Norden AD, Shu HK, Wen PY, Olson JJ (2010) Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 60 (3):166-193
-
(2010)
CA Cancer J Clin
, vol.60
, Issue.3
, pp. 166-193
-
-
Van Meir, E.G.1
Hadjipanayis, C.G.2
Norden, A.D.3
Shu, H.K.4
Wen, P.Y.5
Olson, J.J.6
-
3
-
-
67651085772
-
Signal transduction by focal adhesion kinase in cancer
-
Zhao J, Guan JL (2009) Signal transduction by focal adhesion kinase in cancer. Cancer Metastasis Rev 28(1-2):35-49
-
(2009)
Cancer Metastasis Rev
, vol.28
, Issue.1-2
, pp. 35-49
-
-
Zhao, J.1
Guan, J.L.2
-
4
-
-
3142521875
-
Control of motile and invasive cell phenotypes by focal adhesion kinase
-
Schlaepfer DD, Mitra SK, Ilic D (2004) Control of motile and invasive cell phenotypes by focal adhesion kinase. Biochim Bio-phys Acta 1692(2-3):77-102
-
(2004)
Biochim Bio-phys Acta
, vol.1692
, Issue.2-3
, pp. 77-102
-
-
Schlaepfer, D.D.1
Mitra, S.K.2
Ilic, D.3
-
5
-
-
24944531575
-
High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype
-
Lark AL, Livasy CA, Dressler L, Moore DT, Millikan RC, Geradts J, Iacocca M, Cowan D, Little D, Craven RJ, Cance W (2005) High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype. Mod Pathol 18 (10):1289-1294
-
(2005)
Mod Pathol
, vol.18
, Issue.10
, pp. 1289-1294
-
-
Lark, A.L.1
Livasy, C.A.2
Dressler, L.3
Moore, D.T.4
Millikan, R.C.5
Geradts, J.6
Iacocca, M.7
Cowan, D.8
Little, D.9
Craven, R.J.10
Cance, W.11
-
6
-
-
0037237066
-
Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases: Immunohistochemistry and real-time PCR analyses
-
Lark AL, Livasy CA, Calvo B, Caskey L, Moore DT, Yang X, Cance WG (2003) Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases: immunohistochemistry and real-time PCR analyses. Clin Cancer Res 9(1):215-222
-
(2003)
Clin Cancer Res
, vol.9
, Issue.1
, pp. 215-222
-
-
Lark, A.L.1
Livasy, C.A.2
Calvo, B.3
Caskey, L.4
Moore, D.T.5
Yang, X.6
Cance, W.G.7
-
7
-
-
50349092365
-
Focal adhesion kinase expression in human neuroblastoma: Immunohistochemical and real-time PCR analyses
-
Beierle EA, Massoll NA, Hartwich J, Kurenova EV, Golubovskaya VM, Cance WG, McGrady P, London WB (2008) Focal adhesion kinase expression in human neuroblastoma: immunohistochemical and real-time PCR analyses. Clin Cancer Res 14(11):3299-3305
-
(2008)
Clin Cancer Res
, vol.14
, Issue.11
, pp. 3299-3305
-
-
Beierle, E.A.1
Massoll, N.A.2
Hartwich, J.3
Kurenova, E.V.4
Golubovskaya, V.M.5
Cance, W.G.6
McGrady, P.7
London, W.B.8
-
8
-
-
0141612789
-
FAK signaling in anaplastic astrocytoma and glioblastoma tumors
-
Natarajan M, Hecker TP, Gladson CL (2003) FAK signaling in anaplastic astrocytoma and glioblastoma tumors. Cancer journal (Sudbury, Mass 9 (2):126-133
-
(2003)
Cancer Journal (Sudbury, Mass)
, vol.9
, Issue.2
, pp. 126-133
-
-
Natarajan, M.1
Hecker, T.P.2
Gladson, C.L.3
-
9
-
-
0036570357
-
Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astro-cytoma tumor biopsy samples
-
Hecker TP, Grammer JR, Gillespie GY, Stewart J Jr, Gladson CL (2002) Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astro-cytoma tumor biopsy samples. Cancer Res 62(9):2699-2707
-
(2002)
Cancer Res
, vol.62
, Issue.9
, pp. 2699-2707
-
-
Hecker, T.P.1
Grammer, J.R.2
Gillespie, G.Y.3
Stewart Jr., J.4
Gladson, C.L.5
-
10
-
-
0035423156
-
PTEN-independent induction of caspase-mediated cell death and reduced invasion by the focal adhesion targeting domain (FAT) in human astrocytic brain tumors which highly express focal adhesion kinase (FAK)
-
Jones G, Machado J Jr, Tolnay M, Merlo A (2001) PTEN-independent induction of caspase-mediated cell death and reduced invasion by the focal adhesion targeting domain (FAT) in human astrocytic brain tumors which highly express focal adhesion kinase (FAK). Cancer Res 61(15):5688-5691
-
(2001)
Cancer Res
, vol.61
, Issue.15
, pp. 5688-5691
-
-
Jones, G.1
Machado Jr., J.2
Tolnay, M.3
Merlo, A.4
-
11
-
-
23344434285
-
Herbal medicine and cancer: An introductory overview
-
Treasure J (2005) Herbal medicine and cancer: an introductory overview. Semin Oncol Nurs 21(3):177-183
-
(2005)
Semin Oncol Nurs
, vol.21
, Issue.3
, pp. 177-183
-
-
Treasure, J.1
-
13
-
-
62549153670
-
From here to eternity-The secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond
-
Padhye S, Banerjee S, Ahmad A, Mohammad R, Sarkar FH (2008) From here to eternity-the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond. Canc Ther 6(b):495-510
-
(2008)
Canc Ther
, vol.6
, Issue.B
, pp. 495-510
-
-
Padhye, S.1
Banerjee, S.2
Ahmad, A.3
Mohammad, R.4
Sarkar, F.H.5
-
14
-
-
77958014176
-
Review on molecular and therapeutic potential of thymoquinone in cancer
-
Banerjee S, Padhye S, Azmi A, Wang Z, Philip PA, Kucuk O, Sarkar FH, Mohammad RM (2010) Review on molecular and therapeutic potential of thymoquinone in cancer. Nutr Cancer 62 (7):938-946
-
(2010)
Nutr Cancer
, vol.62
, Issue.7
, pp. 938-946
-
-
Banerjee, S.1
Padhye, S.2
Azmi, A.3
Wang, Z.4
Philip, P.A.5
Kucuk, O.6
Sarkar, F.H.7
Mohammad, R.M.8
-
15
-
-
68349118245
-
Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats
-
Al-Ali A, Alkhawajah AA, Randhawa MA, Shaikh NA (2008) Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats. J Ayub Med Coll Abbottabad 20 (2):25-27
-
(2008)
J Ayub Med Coll Abbottabad
, vol.20
, Issue.2
, pp. 25-27
-
-
Al-Ali, A.1
Alkhawajah, A.A.2
Randhawa, M.A.3
Shaikh, N.A.4
-
16
-
-
41149137253
-
Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models
-
Gali-Muhtasib H, Ocker M, Kuester D, Krueger S, El-Hajj Z, Diestel A, Evert M, El-Najjar N, Peters B, Jurjus A, Roessner A, Schneider-Stock R (2008) Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models. J Cell Mol Med 12(1):330-342
-
(2008)
J Cell Mol Med
, vol.12
, Issue.1
, pp. 330-342
-
-
Gali-Muhtasib, H.1
Ocker, M.2
Kuester, D.3
Krueger, S.4
El-Hajj, Z.5
Diestel, A.6
Evert, M.7
El-Najjar, N.8
Peters, B.9
Jurjus, A.10
Roessner, A.11
Schneider-Stock, R.12
-
17
-
-
77954039888
-
Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo
-
Jafri SH, Glass J, Shi R, Zhang S, Prince M, Kleiner-Hancock H (2010) Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo. J Exp Clin Cancer Res 29:87
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 87
-
-
Jafri, S.H.1
Glass, J.2
Shi, R.3
Zhang, S.4
Prince, M.5
Kleiner-Hancock, H.6
-
18
-
-
51049120763
-
Thymoquinone inhibits tumor angio-genesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways
-
Yi T, Cho SG, Yi Z, Pang X, Rodriguez M, Wang Y, Sethi G, Aggarwal BB, Liu M (2008) Thymoquinone inhibits tumor angio-genesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways. Mol Cancer Ther 7(7):1789-1796
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.7
, pp. 1789-1796
-
-
Yi, T.1
Cho, S.G.2
Yi, Z.3
Pang, X.4
Rodriguez, M.5
Wang, Y.6
Sethi, G.7
Aggarwal, B.B.8
Liu, M.9
-
19
-
-
33750944928
-
The antitumor activity of thymoquinone and thymohydro-quinone in vitro and in vivo
-
Ivankovic S, Stojkovic R, Jukic M, Milos M, Milos M, Jurin M (2006) The antitumor activity of thymoquinone and thymohydro-quinone in vitro and in vivo. Exp Oncol 28(3):220-224
-
(2006)
Exp Oncol
, vol.28
, Issue.3
, pp. 220-224
-
-
Ivankovic, S.1
Stojkovic, R.2
Jukic, M.3
Milos, M.4
Milos, M.5
Jurin, M.6
-
20
-
-
77949263613
-
Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling
-
El-Najjar N, Chatila M, Moukadem H, Vuorela H, Ocker M, Gandesiri M, Schneider-Stock R, Gali-Muhtasib H (2010) Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling. Apoptosis 15(2):183-195
-
(2010)
Apoptosis
, vol.15
, Issue.2
, pp. 183-195
-
-
El-Najjar, N.1
Chatila, M.2
Moukadem, H.3
Vuorela, H.4
Ocker, M.5
Gandesiri, M.6
Schneider-Stock, R.7
Gali-Muhtasib, H.8
-
21
-
-
77957913537
-
Thymo-quinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells
-
Gurung RL, Lim SN, Khaw AK, Soon JF, Shenoy K, Mohamed Ali S, Jayapal M, Sethu S, Baskar R, Hande MP (2010) Thymo-quinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells. PLoS One 5(8):e12124
-
(2010)
PLoS One
, vol.5
, Issue.8
-
-
Gurung, R.L.1
Lim, S.N.2
Khaw, A.K.3
Soon, J.F.4
Shenoy, K.5
Mohamed Ali, S.6
Jayapal, M.7
Sethu, S.8
Baskar, R.9
Hande, M.P.10
-
22
-
-
0034695029
-
Mechanism of calcium oscillations in migrating human astrocytoma cells
-
(Molecular Cell Research)
-
Rondé P, Giannone G, Gerashymova I, Stoeckel H, Takeda K, Haiech J (2000) Mechanism of calcium oscillations in migrating human astrocytoma cells. Biochimica et Biophysica Acta (Molecular Cell Research) 1498:273-280
-
(2000)
Biochimica et Biophysica Acta
, vol.1498
, pp. 273-280
-
-
Rondé, P.1
Giannone, G.2
Gerashymova, I.3
Stoeckel, H.4
Takeda, K.5
Haiech, J.6
-
23
-
-
77951249831
-
Effects of thymoquinone on isolated and cellular proteasomes
-
Cecarini V, Quassinti L, Di Blasio A, Bonfili L, Bramucci M, Lupidi G, Cuccioloni M, Mozzicafreddo M, Angeletti M, Eleuteri AM (2010) Effects of thymoquinone on isolated and cellular proteasomes. FEBS J 277(9):2128-2141
-
(2010)
FEBS J
, vol.277
, Issue.9
, pp. 2128-2141
-
-
Cecarini, V.1
Quassinti, L.2
Di Blasio, A.3
Bonfili, L.4
Bramucci, M.5
Lupidi, G.6
Cuccioloni, M.7
Mozzicafreddo, M.8
Angeletti, M.9
Eleuteri, A.M.10
-
24
-
-
33846904601
-
SiRNA targeted against HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression in hepatocellular carcinoma cell line via ERK1/2 pathway
-
Xu HY, Qian AR, Shang P, Xu J, Kong LM, Bian HJ, Chen ZN (2007) siRNA targeted against HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression in hepatocellular carcinoma cell line via ERK1/2 pathway. Cancer Lett 247(2):336-344
-
(2007)
Cancer Lett
, vol.247
, Issue.2
, pp. 336-344
-
-
Xu, H.Y.1
Qian, A.R.2
Shang, P.3
Xu, J.4
Kong, L.M.5
Bian, H.J.6
Chen, Z.N.7
-
25
-
-
33746122371
-
A role for focal adhesion kinase signaling in tumor necrosis factor-alpha-dependent matrix metalloproteinase-9 production in a cholangiocarcinoma cell line, CCKS1
-
Mon NN, Hasegawa H, Thant AA, Huang P, Tanimura Y, Senga T, Hamaguchi M (2006) A role for focal adhesion kinase signaling in tumor necrosis factor-alpha-dependent matrix metalloproteinase-9 production in a cholangiocarcinoma cell line, CCKS1. Cancer Res 66(13):6778-6784
-
(2006)
Cancer Res
, vol.66
, Issue.13
, pp. 6778-6784
-
-
Mon, N.N.1
Hasegawa, H.2
Thant, A.A.3
Huang, P.4
Tanimura, Y.5
Senga, T.6
Hamaguchi, M.7
-
26
-
-
34447517479
-
FAK signaling in neoplastic disorders: A linkage between inflammation and cancer
-
Mon NN, Ito S, Senga T, Hamaguchi M (2006) FAK signaling in neoplastic disorders: a linkage between inflammation and cancer. Ann N Y Acad Sci 1086:199-212
-
(2006)
Ann N y Acad Sci
, vol.1086
, pp. 199-212
-
-
Mon, N.N.1
Ito, S.2
Senga, T.3
Hamaguchi, M.4
-
27
-
-
0012980550
-
In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone
-
Shoieb AM, Elgayyar M, Dudrick PS, Bell JL, Tithof PK (2003) In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone. Int J Oncol 22(1):107-113
-
(2003)
Int J Oncol
, vol.22
, Issue.1
, pp. 107-113
-
-
Shoieb, A.M.1
Elgayyar, M.2
Dudrick, P.S.3
Bell, J.L.4
Tithof, P.K.5
-
28
-
-
13244285843
-
Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism
-
Gali-Muhtasib H, Diab-Assaf M, Boltze C, Al-Hmaira J, Hartig R, Roessner A, Schneider-Stock R (2004) Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism. Int J Oncol 25 (4):857-866
-
(2004)
Int J Oncol
, vol.25
, Issue.4
, pp. 857-866
-
-
Gali-Muhtasib, H.1
Diab-Assaf, M.2
Boltze, C.3
Al-Hmaira, J.4
Hartig, R.5
Roessner, A.6
Schneider-Stock, R.7
-
29
-
-
26444457920
-
Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells
-
El-Mahdy MA, Zhu Q, Wang QE, Wani G, Wani AA (2005) Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells. Int J Cancer 117(3):409-417
-
(2005)
Int J Cancer
, vol.117
, Issue.3
, pp. 409-417
-
-
El-Mahdy, M.A.1
Zhu, Q.2
Wang, Q.E.3
Wani, G.4
Wani, A.A.5
-
30
-
-
77957800149
-
Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis
-
Abusnina A, Alhosin M, Keravis T, Muller CD, Fuhrmann G, Bronner C, Lugnier C (2011) Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis. Cell Signal 23(1):152-160
-
(2011)
Cell Signal
, vol.23
, Issue.1
, pp. 152-160
-
-
Abusnina, A.1
Alhosin, M.2
Keravis, T.3
Muller, C.D.4
Fuhrmann, G.5
Bronner, C.6
Lugnier, C.7
-
31
-
-
1642586962
-
FAK-Src signalling through pax-illin, ERK and MLCK regulates adhesion disassembly
-
Webb DJ, Donais K, Whitmore LA, Thomas SM, Turner CE, Parsons JT, Horwitz AF (2004) FAK-Src signalling through pax-illin, ERK and MLCK regulates adhesion disassembly. Nat Cell Biol 6(2):154-161
-
(2004)
Nat Cell Biol
, vol.6
, Issue.2
, pp. 154-161
-
-
Webb, D.J.1
Donais, K.2
Whitmore, L.A.3
Thomas, S.M.4
Turner, C.E.5
Parsons, J.T.6
Horwitz, A.F.7
-
32
-
-
77951184829
-
Cellular functions of FAK kinases: Insight into molecular mechanisms and novel functions
-
Schaller MD (2010) Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions. J Cell Sci 123(Pt 7):1007-1013
-
(2010)
J Cell Sci
, vol.123
, Issue.PART 7
, pp. 1007-1013
-
-
Schaller, M.D.1
-
33
-
-
0037509990
-
Focal adhesion kinase: The first 10 years
-
Parsons JT (2003) Focal adhesion kinase: the first 10 years. J Cell Sci 116(Pt 8):1409-1416
-
(2003)
J Cell Sci
, vol.116
, Issue.PART 8
, pp. 1409-1416
-
-
Parsons, J.T.1
-
34
-
-
11144285417
-
Differential expression of protease activated receptor 1 (Par1) and pY397FAK in benign and malignant human ovarian tissue samples
-
Grisaru-Granovsky S, Salah Z, Maoz M, Pruss D, Beller U, Bar-Shavit R (2005) Differential expression of protease activated receptor 1 (Par1) and pY397FAK in benign and malignant human ovarian tissue samples. Int J Cancer 113(3):372-378
-
(2005)
Int J Cancer
, vol.113
, Issue.3
, pp. 372-378
-
-
Grisaru-Granovsky, S.1
Salah, Z.2
Maoz, M.3
Pruss, D.4
Beller, U.5
Bar-Shavit, R.6
-
35
-
-
0242491536
-
Expression of focal adhesion kinase and phosphorylated focal adhesion kinase in squamous cell carcinoma of the larynx
-
Aronsohn MS, Brown HM, Hauptman G, Kornberg LJ (2003) Expression of focal adhesion kinase and phosphorylated focal adhesion kinase in squamous cell carcinoma of the larynx. Laryngoscope 113(11):1944-1948
-
(2003)
Laryngoscope
, vol.113
, Issue.11
, pp. 1944-1948
-
-
Aronsohn, M.S.1
Brown, H.M.2
Hauptman, G.3
Kornberg, L.J.4
-
36
-
-
27644570788
-
Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397
-
Hamadi A, Bouali M, Dontenwill M, Stoeckel H, Takeda K, Ronde P (2005) Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397. J Cell Sci 118 (Pt 19):4415-4425
-
(2005)
J Cell Sci
, vol.118
, Issue.PART 19
, pp. 4415-4425
-
-
Hamadi, A.1
Bouali, M.2
Dontenwill, M.3
Stoeckel, H.4
Takeda, K.5
Ronde, P.6
-
37
-
-
13944282937
-
Identification of Src-specific phosphorylation site on focal adhesion kinase: Dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior
-
Brunton VG, Avizienyte E, Fincham VJ, Serrels B, Metcalf CA 3rd, Sawyer TK, Frame MC (2005) Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior. Cancer Res 65(4):1335-1342
-
(2005)
Cancer Res
, vol.65
, Issue.4
, pp. 1335-1342
-
-
Brunton, V.G.1
Avizienyte, E.2
Fincham, V.J.3
Serrels, B.4
Metcalf III, C.A.5
Sawyer, T.K.6
Frame, M.C.7
-
38
-
-
79953309890
-
FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion
-
Deramaudt TB, Dujardin D, Hamadi A, Noulet F, Kolli K, De Mey J, Takeda K, Ronde P (2011) FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion. Mol Biol Cell 22(7):964-975
-
(2011)
Mol Biol Cell
, vol.22
, Issue.7
, pp. 964-975
-
-
Deramaudt, T.B.1
Dujardin, D.2
Hamadi, A.3
Noulet, F.4
Kolli, K.5
De Mey, J.6
Takeda, K.7
Ronde, P.8
-
39
-
-
52149083736
-
Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis
-
Kaneda T, Sonoda Y, Ando K, Suzuki T, Sasaki Y, Oshio T, Tago M, Kasahara T (2008) Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis. Cancer Lett 270(2):354-361
-
(2008)
Cancer Lett
, vol.270
, Issue.2
, pp. 354-361
-
-
Kaneda, T.1
Sonoda, Y.2
Ando, K.3
Suzuki, T.4
Sasaki, Y.5
Oshio, T.6
Tago, M.7
Kasahara, T.8
-
40
-
-
77952140698
-
Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: Implications for the development of novel cancer therapies
-
Torres MP, Ponnusamy MP, Chakraborty S, Smith LM, Das S, Arafat HA, Batra SK (2010) Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapies. Mol Cancer Ther 9 (5):1419-1431
-
(2010)
Mol Cancer Ther
, vol.9
, Issue.5
, pp. 1419-1431
-
-
Torres, M.P.1
Ponnusamy, M.P.2
Chakraborty, S.3
Smith, L.M.4
Das, S.5
Arafat, H.A.6
Batra, S.K.7
-
41
-
-
84875507107
-
Thymoquinone inhibits angiogenesis and prostate tumor growth by suppressing MAPK signaling pathways
-
Yi T, Cho SG, Yi Z, Luo W, Wang Y, Sethi G, Aggarwal BB, Liu M (2008) Thymoquinone inhibits angiogenesis and prostate tumor growth by suppressing MAPK signaling pathways. The FASEB Journal 22:654.1
-
(2008)
The FASEB Journal
, vol.22
, pp. 6541
-
-
Yi, T.1
Cho, S.G.2
Yi, Z.3
Luo, W.4
Wang, Y.5
Sethi, G.6
Aggarwal, B.B.7
Liu, M.8
-
42
-
-
77953178795
-
Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: Role of reactive oxygen species
-
Koka PS, Mondal D, Schultz M, Abdel-Mageed AB, Agrawal KC (2010) Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species. Experimental biology and medicine (Maywood) 235(6):751-760
-
(2010)
Experimental Biology and Medicine (Maywood)
, vol.235
, Issue.6
, pp. 751-760
-
-
Koka, P.S.1
Mondal, D.2
Schultz, M.3
Abdel-Mageed, A.B.4
Agrawal, K.C.5
-
43
-
-
0029979722
-
Phosphory-lation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase
-
Chen HC, Appeddu PA, Isoda H, Guan JL (1996) Phosphory-lation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase. J Biol Chem 271 (42):26329-34
-
(1996)
J Biol Chem
, vol.271
, Issue.42
, pp. 26329-26334
-
-
Chen, H.C.1
Appeddu, P.A.2
Isoda, H.3
Guan, J.L.4
-
44
-
-
21644466387
-
Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53
-
Golubovskaya VM, Finch R, Cance WG (2005) Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53. J Biol Chem 280 (26):25008-21
-
(2005)
J Biol Chem
, vol.280
, Issue.26
, pp. 25008-25021
-
-
Golubovskaya, V.M.1
Finch, R.2
Cance, W.G.3
-
45
-
-
79958155946
-
Post-translational modifications of PTEN and their potential therapeutic implications
-
Singh G, Chan AM (2001) Post-translational modifications of PTEN and their potential therapeutic implications. Curr Cancer Drug Targets 11(5):536-47
-
(2001)
Curr Cancer Drug Targets
, vol.11
, Issue.5
, pp. 536-547
-
-
Singh, G.1
Chan, A.M.2
-
46
-
-
0033606767
-
Shc and FAK differentially regulate cell motility and directionality modulated by PTEN
-
Gu J, Tamura M, Pankov R, Danen EH, Takino T, Matsumoto K, Yamada KM (1999) Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. J Cell Biol 146:389-403
-
(1999)
J Cell Biol
, vol.146
, pp. 389-403
-
-
Gu, J.1
Tamura, M.2
Pankov, R.3
Danen, E.H.4
Takino, T.5
Matsumoto, K.6
Yamada, K.M.7
-
47
-
-
0037135560
-
Calcium oscillations trigger focal adhesion disassembly in human U87 astrocytoma cells
-
Giannone G, Rondé P, Gaire M, Haiech J, Takeda K (2002) Calcium oscillations trigger focal adhesion disassembly in human U87 astrocytoma cells. J Biol Chem 277:26364-26371
-
(2002)
J Biol Chem
, vol.277
, pp. 26364-26371
-
-
Giannone, G.1
Rondé, P.2
Gaire, M.3
Haiech, J.4
Takeda, K.5
-
48
-
-
31544447172
-
Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway
-
Hu B, Jarzynka MJ, Guo P, Imanishi Y, Schlaepfer DD, Cheng SY (2006) Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway. Cancer Res 66(2):775-783
-
(2006)
Cancer Res
, vol.66
, Issue.2
, pp. 775-783
-
-
Hu, B.1
Jarzynka, M.J.2
Guo, P.3
Imanishi, Y.4
Schlaepfer, D.D.5
Cheng, S.Y.6
-
49
-
-
4444246234
-
Suppression of invasion in human U87 glioma cells by adenovirus-mediated co-transfer of TIMP-2 and PTEN gene
-
Lu W, Zhou X, Hong B, Liu J, Yue Z (2004) Suppression of invasion in human U87 glioma cells by adenovirus-mediated co-transfer of TIMP-2 and PTEN gene. Cancer Lett 214 (2):205-213
-
(2004)
Cancer Lett
, vol.214
, Issue.2
, pp. 205-213
-
-
Lu, W.1
Zhou, X.2
Hong, B.3
Liu, J.4
Yue, Z.5
-
50
-
-
0033494157
-
Matrix metalloproteinase inhibitors: Applications in oncology
-
Yip D, Ahmad A, Karapetis CS, Hawkins CA, Harper PG (1999) Matrix metalloproteinase inhibitors: applications in oncology. Invest New Drugs 17(4):387-399
-
(1999)
Invest New Drugs
, vol.17
, Issue.4
, pp. 387-399
-
-
Yip, D.1
Ahmad, A.2
Karapetis, C.S.3
Hawkins, C.A.4
Harper, P.G.5
-
51
-
-
0031049327
-
Mechanisms of glioma invasion: Role of matrix-metalloproteinases
-
Uhm JH, Dooley NP, Villemure JG, Yong VW (1997) Mechanisms of glioma invasion: role of matrix-metalloproteinases. Can J Neu-rol Sci 24(1):3-15
-
(1997)
Can J Neu-rol Sci
, vol.24
, Issue.1
, pp. 3-15
-
-
Uhm, J.H.1
Dooley, N.P.2
Villemure, J.G.3
Yong, V.W.4
-
52
-
-
65349118139
-
Role of hyaluronan in glioma invasion
-
Park JB, Kwak HJ, Lee SH (2008) Role of hyaluronan in glioma invasion. Cell Adh Migr 2(3):202-207
-
(2008)
Cell Adh Migr
, vol.2
, Issue.3
, pp. 202-207
-
-
Park, J.B.1
Kwak, H.J.2
Lee, S.H.3
-
53
-
-
0028609382
-
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
Schlaepfer DD, Hanks SK, Hunter T, van der Geer P (1994) Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372(6508):786-791
-
(1994)
Nature
, vol.372
, Issue.6508
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
Van Der Geer, P.4
-
54
-
-
0030926774
-
Focal adhesion kinase overex-pression enhances ras-dependent integrin signaling to ERK2/mito-gen-activated protein kinase through interactions with and activation of c-Src
-
Schlaepfer DD, Hunter T (1997) Focal adhesion kinase overex-pression enhances ras-dependent integrin signaling to ERK2/mito-gen-activated protein kinase through interactions with and activation of c-Src. J Biol Chem 272(20):13189-13195
-
(1997)
J Biol Chem
, vol.272
, Issue.20
, pp. 13189-13195
-
-
Schlaepfer, D.D.1
Hunter, T.2
-
55
-
-
0031921101
-
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mito-gen-activated protein kinase: Summation of both c-Src-and focal adhesion kinase-initiated tyrosine phosphorylation events
-
Schlaepfer DD, Jones KC, Hunter T (1998) Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mito-gen-activated protein kinase: summation of both c-Src-and focal adhesion kinase-initiated tyrosine phosphorylation events. Mol Cell Biol 18(5):2571-2585
-
(1998)
Mol Cell Biol
, vol.18
, Issue.5
, pp. 2571-2585
-
-
Schlaepfer, D.D.1
Jones, K.C.2
Hunter, T.3
|