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Volumn 41, Issue 2, 2013, Pages 943-960

Trypanosoma brucei BRCA2 acts in a life cycle-specific genome stability process and dictates BRC repeat number-dependent RAD51 subnuclear dynamics

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN; RAD51 PROTEIN; RECOMBINASE; VARIANT SURFACE GLYCOPROTEIN;

EID: 84875453879     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks1192     Document Type: Article
Times cited : (26)

References (64)
  • 1
    • 84864407356 scopus 로고    scopus 로고
    • Microbial antigenic variation mediated by homologous DNA recombination
    • Dec 25 doi: 10.1111/J.1574-6976.2011.00321.x; epup ahead of print
    • Vink, C., Rudenko, G. and Seifert, H.S. (2011) Microbial antigenic variation mediated by homologous DNA recombination. FEMS Microbiol. Rev., Dec 25 (doi: 10.1111/J.1574-6976.2011.00321.x; epup ahead of print).
    • (2011) FEMS Microbiol. Rev.
    • Vink, C.1    Rudenko, G.2    Seifert, H.S.3
  • 2
    • 72749109190 scopus 로고    scopus 로고
    • Antigenic variation in the African trypanosome: Molecular mechanisms and phenotypic complexity
    • Morrison, L.J., Marcello, L. and McCulloch, R. (2009) Antigenic variation in the African trypanosome: molecular mechanisms and phenotypic complexity. Cell Microbiol., 11, 1724-1734.
    • (2009) Cell Microbiol , vol.11 , pp. 1724-1734
    • Morrison, L.J.1    Marcello, L.2    McCulloch, R.3
  • 3
    • 8744298412 scopus 로고    scopus 로고
    • Isolation of the repertoire of VSG expression site containing telomeres of Trypanosoma brucei 427 using transformation-associated recombination in yeast
    • DOI 10.1101/gr.2955304
    • Becker, M., Aitcheson, N., Byles, E., Wickstead, B., Louis, E. and Rudenko, G. (2004) Isolation of the repertoire of VSG expression site containing telomeres of Trypanosoma brucei 427 using transformation-associated recombination in yeast. Genome Res., 14, 2319-2329. (Pubitemid 39517339)
    • (2004) Genome Research , vol.14 , Issue.11 , pp. 2319-2329
    • Becker, M.1    Aitcheson, N.2    Byles, E.3    Wickstead, B.4    Louis, E.5    Rudenko, G.6
  • 4
    • 34548396688 scopus 로고    scopus 로고
    • Analysis of the VSG gene silent archive in Trypanosoma brucei reveals that mosaic gene expression is prominent in antigenic variation and is favored by archive substructure
    • DOI 10.1101/gr.6421207
    • Marcello, L. and Barry, J.D. (2007) Analysis of the VSG gene silent archive in Trypanosoma brucei reveals that mosaic gene expression is prominent in antigenic variation and is favored by archive substructure. Genome Res., 17, 1344-1352. (Pubitemid 47360909)
    • (2007) Genome Research , vol.17 , Issue.9 , pp. 1344-1352
    • Marcello, L.1    Barry, J.D.2
  • 5
    • 78149425175 scopus 로고    scopus 로고
    • Regulation of homologous recombination in eukaryotes
    • Heyer, W.D., Ehmsen, K.T. and Liu, J. (2010) Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet., 44, 113-139.
    • (2010) Annu. Rev. Genet , vol.44 , pp. 113-139
    • Heyer, W.D.1    Ehmsen, K.T.2    Liu, J.3
  • 6
    • 0032723013 scopus 로고    scopus 로고
    • A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variation
    • McCulloch, R. and Barry, J.D. (1999) A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variation. Genes Dev., 13, 2875-2888.
    • (1999) Genes Dev , vol.13 , pp. 2875-2888
    • McCulloch, R.1    Barry, J.D.2
  • 7
    • 79960186615 scopus 로고    scopus 로고
    • Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation
    • Dobson, R., Stockdale, C., Lapsley, C., Wilkes, J. and McCulloch, R. (2011) Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation. Mol. Microbiol., 81, 434-456.
    • (2011) Mol. Microbiol , vol.81 , pp. 434-456
    • Dobson, R.1    Stockdale, C.2    Lapsley, C.3    Wilkes, J.4    McCulloch, R.5
  • 8
    • 29244484238 scopus 로고    scopus 로고
    • Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation
    • DOI 10.1093/nar/gki996
    • Proudfoot, C. and McCulloch, R. (2005) Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation. Nucleic Acids Res., 33, 6906-6919. (Pubitemid 41830494)
    • (2005) Nucleic Acids Research , vol.33 , Issue.21 , pp. 6906-6919
    • Proudfoot, C.1    McCulloch, R.2
  • 9
    • 77957655729 scopus 로고    scopus 로고
    • TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei
    • Kim, H.S. and Cross, G.A. (2010) TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei. PLoS Pathog., 6, e1000992.
    • (2010) PLoS Pathog , vol.6
    • Kim, H.S.1    Cross, G.A.2
  • 10
    • 80053222054 scopus 로고    scopus 로고
    • Identification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation
    • Kim, H.S. and Cross, G.A. (2011) Identification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation. PLoS One, 6, e25313.
    • (2011) PLoS One , vol.6
    • Kim, H.S.1    Cross, G.A.2
  • 11
    • 0041378027 scopus 로고    scopus 로고
    • Sequence fingerprints in BRCA2 and RAD51: Implications for DNA repair and cancer
    • DOI 10.1016/S1568-7864(03)00097-1
    • Lo, T., Pellegrini, L., Venkitaraman, A.R. and Blundell, T.L. (2003) Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer. DNA Repair (Amst.), 2, 1015-1028. (Pubitemid 37088163)
    • (2003) DNA Repair , vol.2 , Issue.9 , pp. 1015-1028
    • Lo, T.1    Pellegrini, L.2    Venkitaraman, A.R.3    Blundell, T.L.4
  • 12
    • 0036752956 scopus 로고    scopus 로고
    • BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis
    • DOI 10.1016/S1097-2765(02)00632-9
    • Kojic, M., Kostrub, C.F., Buchman, A.R. and Holloman, W.K. (2002) BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis. Mol. Cell, 10, 683-691. (Pubitemid 35284183)
    • (2002) Molecular Cell , vol.10 , Issue.3 , pp. 683-691
    • Kojic, M.1    Kostrub, C.F.2    Buchman, A.R.3    Holloman, W.K.4
  • 14
    • 0030140414 scopus 로고    scopus 로고
    • Internal repeats in the BRCA2 protein sequence
    • Bork, P., Blomberg, N. and Nilges, M. (1996) Internal repeats in the BRCA2 protein sequence. Nat. Genet., 13, 22-23.
    • (1996) Nat. Genet , vol.13 , pp. 22-23
    • Bork, P.1    Blomberg, N.2    Nilges, M.3
  • 15
    • 15844373362 scopus 로고    scopus 로고
    • CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
    • DOI 10.1038/nature03404
    • Esashi, F., Christ, N., Gannon, J., Liu, Y., Hunt, T., Jasin, M. and West, S.C. (2005) CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature, 434, 598-604. (Pubitemid 40488546)
    • (2005) Nature , vol.434 , Issue.7033 , pp. 598-604
    • Esashi, F.1    Christ, N.2    Cannon, J.3    Liu, Y.4    Hunt, T.5    Jasin, M.6    West, S.C.7
  • 16
    • 34249878748 scopus 로고    scopus 로고
    • Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2
    • DOI 10.1038/nsmb1245, PII NSMB1245
    • Esashi, F., Galkin, V.E., Yu, X., Egelman, E.H. and West, S.C. (2007) Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2. Nat. Struct. Mol. Biol., 14, 468-474. (Pubitemid 46871809)
    • (2007) Nature Structural and Molecular Biology , vol.14 , Issue.6 , pp. 468-474
    • Esashi, F.1    Galkin, V.E.2    Yu, X.3    Egelman, E.H.4    West, S.C.5
  • 17
    • 34249887673 scopus 로고    scopus 로고
    • Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats
    • DOI 10.1038/nsmb1251, PII NSMB1251
    • Davies, O.R. and Pellegrini, L. (2007) Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats. Nat. Struct. Mol. Biol., 14, 475-483. (Pubitemid 46871813)
    • (2007) Nature Structural and Molecular Biology , vol.14 , Issue.6 , pp. 475-483
    • Davies, O.R.1    Pellegrini, L.2
  • 18
    • 34147195807 scopus 로고    scopus 로고
    • Dss1 interaction with Brh2 as a regulatory mechanism for recombinational repair
    • DOI 10.1128/MCB.01907-06
    • Zhou, Q., Kojic, M., Cao, Z., Lisby, M., Mazloum, N.A. and Holloman, W.K. (2007) Dss1 interaction with Brh2 as a regulatory mechanism for recombinational repair. Mol. Cell Biol., 27, 2512-2526. (Pubitemid 46581343)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.7 , pp. 2512-2526
    • Zhou, Q.1    Kojic, M.2    Cao, Z.3    Lisby, M.4    Mazloum, N.A.5    Holloman, W.K.6
  • 19
    • 34249911218 scopus 로고    scopus 로고
    • RAD51 BRCA2 and DNA repair: A partial resolution
    • Lord, C.J. and Ashworth, A. (2007) RAD51, BRCA2 and DNA repair: a partial resolution. Nat. Struct. Mol. Biol., 14, 461-462.
    • (2007) Nat. Struct. Mol. Biol , vol.14 , pp. 461-462
    • Lord, C.J.1    Ashworth, A.2
  • 21
    • 79960597176 scopus 로고    scopus 로고
    • Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms
    • Carreira, A. and Kowalczykowski, S.C. (2011) Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms. Proc. Natl Acad. Sci. USA., 108, 10448-10453.
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 10448-10453
    • Carreira, A.1    Kowalczykowski, S.C.2
  • 22
    • 69449089443 scopus 로고    scopus 로고
    • The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single-versus double-stranded DNA to stimulate strand exchange
    • Shivji, M.K., Mukund, S.R., Rajendra, E., Chen, S., Short, J.M., Savill, J., Klenerman, D. and Venkitaraman, A.R. (2009) The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single-versus double-stranded DNA to stimulate strand exchange. Proc. Natl Acad. Sci. USA., 106, 13254-13259.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 13254-13259
    • Shivji, M.K.1    Mukund, S.R.2    Rajendra, E.3    Chen, S.4    Short, J.M.5    Savill, J.6    Klenerman, D.7    Venkitaraman, A.R.8
  • 24
    • 67649881097 scopus 로고    scopus 로고
    • The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry
    • Ayoub, N., Rajendra, E., Su, X., Jeyasekharan, A.D., Mahen, R. and Venkitaraman, A.R. (2009) The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry. Curr. Biol., 19, 1075-1085.
    • (2009) Curr. Biol , vol.19 , pp. 1075-1085
    • Ayoub, N.1    Rajendra, E.2    Su, X.3    Jeyasekharan, A.D.4    Mahen, R.5    Venkitaraman, A.R.6
  • 25
    • 79955799175 scopus 로고    scopus 로고
    • Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11
    • Schlacher, K., Christ, N., Siaud, N., Egashira, A., Wu, H. and Jasin, M. (2011) Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell, 145, 529-542.
    • (2011) Cell , vol.145 , pp. 529-542
    • Schlacher, K.1    Christ, N.2    Siaud, N.3    Egashira, A.4    Wu, H.5    Jasin, M.6
  • 26
    • 78549251695 scopus 로고    scopus 로고
    • Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis
    • Hashimoto, Y., Chaudhuri, A.R., Lopes, M. and Costanzo, V. (2010) Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis. Nat. Struct. Mol. Biol., 17, 1305-1311.
    • (2010) Nat. Struct. Mol. Biol , vol.17 , pp. 1305-1311
    • Hashimoto, Y.1    Chaudhuri, A.R.2    Lopes, M.3    Costanzo, V.4
  • 27
    • 43449106468 scopus 로고    scopus 로고
    • Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination
    • DOI 10.1111/j.1365-2958.2008.06230.x
    • Hartley, C.L. and McCulloch, R. (2008) Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination. Mol. Microbiol., 68, 1237-1251. (Pubitemid 351670200)
    • (2008) Molecular Microbiology , vol.68 , Issue.5 , pp. 1237-1251
    • Hartley, C.L.1    McCulloch, R.2
  • 28
    • 33646931526 scopus 로고    scopus 로고
    • Interaction between Arabidopsis Brca2 and its partners Rad51, Dmc1, and Dss1
    • DOI 10.1104/pp.105.075838
    • Dray, E., Siaud, N., Dubois, E. and Doutriaux, M.P. (2006) Interaction between Arabidopsis Brca2 and its partners Rad51, Dmc1, and Dss1. Plant Physiol., 140, 1059-1069. (Pubitemid 43956257)
    • (2006) Plant Physiology , vol.140 , Issue.3 , pp. 1059-1069
    • Dray, E.1    Siaud, N.2    Dubois, E.3    Doutriaux, M.-P.4
  • 29
    • 70350107177 scopus 로고    scopus 로고
    • Molecular evolution of a Drosophila homolog of human BRCA2
    • Bennett, S.M. and Noor, M.A. (2009) Molecular evolution of a Drosophila homolog of human BRCA2. Genetica, 137, 213-219.
    • (2009) Genetica , vol.137 , pp. 213-219
    • Bennett, S.M.1    Noor, M.A.2
  • 30
    • 47949091926 scopus 로고    scopus 로고
    • Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei
    • Alsford, S. and Horn, D. (2008) Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei. Mol. Biochem. Parasitol., 161, 76-79.
    • (2008) Mol. Biochem. Parasitol , vol.161 , pp. 76-79
    • Alsford, S.1    Horn, D.2
  • 31
    • 0030612893 scopus 로고    scopus 로고
    • The alamar blue® assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro
    • DOI 10.1016/S0001-706X(97)00079-X, PII S0001706X9700079X
    • Raz, B., Iten, M., Grether-Buhler, Y., Kaminsky, R. and Brun, R. (1997) The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro. Acta Trop., 68, 139-147. (Pubitemid 27438330)
    • (1997) Acta Tropica , vol.68 , Issue.2 , pp. 139-147
    • Raz, B.1    Iten, M.2    Grether-Buhler, Y.3    Kaminsky, R.4    Brun, R.5
  • 32
    • 0038397337 scopus 로고    scopus 로고
    • Exportin 1 mediates nuclear export of the kinetoplastid spliced leader RNA
    • DOI 10.1128/EC.2.2.222-230.2003
    • Zeiner, G.M., Sturm, N.R. and Campbell, D.A. (2003) Exportin 1 mediates nuclear export of the kinetoplastid spliced leader RNA. Eukaryot. Cell, 2, 222-230. (Pubitemid 36562361)
    • (2003) Eukaryotic Cell , vol.2 , Issue.2 , pp. 222-230
    • Zeiner, G.M.1    Sturm, N.R.2    Campbell, D.A.3
  • 33
    • 0019848907 scopus 로고
    • Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage
    • Giloni, L., Takeshita, M., Johnson, F., Iden, C. and Grollman, A.P. (1981) Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage. J. Biol. Chem., 256, 8608-8615. (Pubitemid 12254808)
    • (1981) Journal of Biological Chemistry , vol.256 , Issue.16 , pp. 8608-8615
    • Giloni, L.1    Takeshita, M.2    Johnson, F.3
  • 38
    • 68249125048 scopus 로고    scopus 로고
    • Choreography of recombination proteins during the DNA damage response
    • Lisby, M. and Rothstein, R. (2009) Choreography of recombination proteins during the DNA damage response. DNA Repair, 8, 1068-1076.
    • (2009) DNA Repair , vol.8 , pp. 1068-1076
    • Lisby, M.1    Rothstein, R.2
  • 40
    • 0032145092 scopus 로고    scopus 로고
    • The molecular karyotype of the megabase chromosomes of Trypanosoma brucei and the assignment of chromosome markers
    • DOI 10.1016/S0166-6851(98)00054-1, PII S0166685198000541
    • Melville, S.E., Leech, V., Gerrard, C.S., Tait, A. and Blackwell, J.M. (1998) The molecular karyotype of the megabase chromosomes of Trypanosoma brucei and the assignment of chromosome markers. Mol. Biochem. Parasitol., 94, 155-173. (Pubitemid 28377283)
    • (1998) Molecular and Biochemical Parasitology , vol.94 , Issue.2 , pp. 155-173
    • Melville, S.E.1    Leech, V.2    Gerrard, C.S.3    Tait, A.4    Blackwell, J.M.5
  • 41
    • 33748280640 scopus 로고    scopus 로고
    • Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length
    • DOI 10.1101/gr.5147406
    • Callejas, S., Leech, V., Reitter, C. and Melville, S. (2006) Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length. Genome Res., 16, 1109-1118. (Pubitemid 44320398)
    • (2006) Genome Research , vol.16 , Issue.9 , pp. 1109-1118
    • Callejas, S.1    Leech, V.2    Reitter, C.3    Melville, S.4
  • 43
    • 0037468267 scopus 로고    scopus 로고
    • BRCA2-dependent and independent formation of RAD51 nuclear foci
    • DOI 10.1038/sj.onc.1206263
    • Tarsounas, M., Davies, D. and West, S.C. (2003) BRCA2-dependent and independent formation of RAD51 nuclear foci. Oncogene, 22, 1115-1123. (Pubitemid 36363377)
    • (2003) Oncogene , vol.22 , Issue.8 , pp. 1115-1123
    • Tarsounas, M.1    Davies, D.2    West, S.C.3
  • 44
    • 36549037672 scopus 로고    scopus 로고
    • Functional analysis of Drosophila melanogaster BRCA2 in DNA repair
    • DOI 10.1016/j.dnarep.2007.07.013, PII S1568786407002625
    • Brough, R., Wei, D., Leulier, S., Lord, C.J., Rong, Y.S. and Ashworth, A. (2008) Functional analysis of Drosophila melanogaster BRCA2 in DNA repair. DNA Repair, 7, 10-19. (Pubitemid 350184401)
    • (2008) DNA Repair , vol.7 , Issue.1 , pp. 10-19
    • Brough, R.1    Wei, D.2    Leulier, S.3    Lord, C.J.4    Rong, Y.S.5    Ashworth, A.6
  • 45
    • 0347364719 scopus 로고    scopus 로고
    • Coordination of cell cycle and cytokinesis in Trypanosoma brucei
    • DOI 10.1016/j.mib.2003.10.010
    • McKean, P.G. (2003) Coordination of cell cycle and cytokinesis in Trypanosoma brucei. Curr. Opin. Microbiol., 6, 600-607. (Pubitemid 38020057)
    • (2003) Current Opinion in Microbiology , vol.6 , Issue.6 , pp. 600-607
    • McKean, P.G.1
  • 46
    • 0037135587 scopus 로고    scopus 로고
    • Inactivation of Mre11 does not affect VSG gene duplication mediated by homologous recombination in Trypanosoma brucei
    • DOI 10.1074/jbc.M203205200
    • Robinson, N.P., McCulloch, R., Conway, C., Browitt, A and Barry, J.D. (2002) Inactivation of Mre11 does not affect VSG gene duplication mediated by homologous recombination in Trypanosoma brucei. J. Biol. Chem., 277, 26185-26193. (Pubitemid 34967105)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.29 , pp. 26185-26193
    • Robinson, N.P.1    McCulloch, R.2    Conway, C.3    Browitt, A.4    David Barry, J.5
  • 47
    • 15044340651 scopus 로고    scopus 로고
    • Brh2-Dss1 interplay enables properly controlled recombination in Ustilago maydis
    • DOI 10.1128/MCB.25.7.2547-2557.2005
    • Kojic, M., Zhou, Q., Lisby, M. and Holloman, W.K. (2005) Brh2-Dss1 interplay enables properly controlled recombination in Ustilago maydis. Mol. Cell Biol., 25, 2547-2557. (Pubitemid 40381621)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.7 , pp. 2547-2557
    • Kojic, M.1    Zhou, Q.2    Lisby, M.3    Holloman, W.K.4
  • 48
    • 43349103776 scopus 로고    scopus 로고
    • Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes
    • DOI 10.1093/nar/gkn104
    • Glover, L., McCulloch, R. and Horn, D. (2008) Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes. Nucleic Acids Res., 36, 2608-2618. (Pubitemid 351659575)
    • (2008) Nucleic Acids Research , vol.36 , Issue.8 , pp. 2608-2618
    • Glover, L.1    McCulloch, R.2    Horn, D.3
  • 49
    • 0035400352 scopus 로고    scopus 로고
    • Identification and characterisation of a RAD51 gene from Leishmania major
    • DOI 10.1016/S0166-6851(01)00288-2, PII S0166685101002882
    • McKean, P.G., Keen, J.K., Smith, D.F. and Benson, F.E. (2001) Identification and characterisation of a RAD51 gene from Leishmania major. Mol. Biochem. Parasitol., 115, 209-216. (Pubitemid 32566230)
    • (2001) Molecular and Biochemical Parasitology , vol.115 , Issue.2 , pp. 209-216
    • McKean, P.G.1    Keen, J.K.2    Smith, D.F.3    Benson, F.E.4
  • 52
    • 80054837086 scopus 로고    scopus 로고
    • Characterization of Brca2-deficient plants excludes the role of NHEJ and SSA in the meiotic chromosomal defect phenotype
    • Dumont, M., Massot, S., Doutriaux, M.P. and Gratias, A. (2011) Characterization of Brca2-deficient plants excludes the role of NHEJ and SSA in the meiotic chromosomal defect phenotype. PLoS One, 6, e26696.
    • (2011) PLoS One , vol.6
    • Dumont, M.1    Massot, S.2    Doutriaux, M.P.3    Gratias, A.4
  • 53
    • 63449092932 scopus 로고    scopus 로고
    • Essential role of brc-2 in chromosome integrity of germ cells in C. elegans
    • Ko, E., Lee, J. and Lee, H. (2008) Essential role of brc-2 in chromosome integrity of germ cells in C. elegans. Mol. Cells, 26, 590-594.
    • (2008) Mol. Cells , vol.26 , pp. 590-594
    • Ko, E.1    Lee, J.2    Lee, H.3
  • 55
    • 57549110465 scopus 로고    scopus 로고
    • A kinetoplastid BRCA2 interacts with DNA replication protein CDC45
    • Oyola, S.O., Bringaud, F. and Melville, S.E. (2008) A kinetoplastid BRCA2 interacts with DNA replication protein CDC45. Int. J. Parasitol., 39, 59-69.
    • (2008) Int. J. Parasitol , vol.39 , pp. 59-69
    • Oyola, S.O.1    Bringaud, F.2    Melville, S.E.3
  • 56
    • 0033166981 scopus 로고    scopus 로고
    • Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2
    • DOI 10.1016/S1097-2765(00)80182-3
    • Lee, H., Trainer, A.H., Friedman, L.S., Thistlethwaite, F.C., Evans, M.J., Ponder, B.A. and Venkitaraman, A.R. (1999) Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2. Mol. Cell, 4, 1-10. (Pubitemid 29386126)
    • (1999) Molecular Cell , vol.4 , Issue.1 , pp. 1-10
    • Lee, H.1    Trainer, A.H.2    Friedman, L.S.3    Thistlethwaite, F.C.4    Evans, M.J.5    Ponder, B.A.J.6    Venkitaraman, A.R.7
  • 57
    • 0034653736 scopus 로고    scopus 로고
    • Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1
    • Futamura, M., Arakawa, H., Matsuda, K., Katagiri, T., Saji, S., Miki, Y. and Nakamura, Y. (2000) Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1. Cancer Res., 60, 1531-1535. (Pubitemid 30183420)
    • (2000) Cancer Research , vol.60 , Issue.6 , pp. 1531-1535
    • Futamura, M.1    Arakawa, H.2    Matsuda, K.3    Katagiri, T.4    Saji, S.5    Miki, Y.6    Nakamura, Y.7
  • 58
    • 0035951405 scopus 로고    scopus 로고
    • A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression
    • DOI 10.1016/S0092-8674(01)00209-4
    • Marmorstein, L.Y., Kinev, A.V., Chan, G.K., Bochar, D.A., Beniya, H., Epstein, J.A., Yen, T.J. and Shiekhattar, R. (2001) A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression. Cell, 104, 247-257. (Pubitemid 32174840)
    • (2001) Cell , vol.104 , Issue.2 , pp. 247-257
    • Marmorstein, L.Y.1    Kinev, A.V.2    Chan, G.K.T.3    Bochar, D.A.4    Beniya, H.5    Epstein, J.A.6    Yen, T.J.7    Shiekhattar, R.8
  • 59
    • 7444222440 scopus 로고    scopus 로고
    • Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2
    • DOI 10.1126/science.1102574
    • Daniels, M.J., Wang, Y., Lee, M. and Venkitaraman, A.R. (2004) Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2. Science, 306, 876-879. (Pubitemid 39446997)
    • (2004) Science , vol.306 , Issue.5697 , pp. 876-879
    • Daniels, M.J.1    Wang, Y.2    Lee, M.3    Venkitaraman, A.R.4
  • 62
    • 30644471559 scopus 로고    scopus 로고
    • Rec2 interplay with both Brh2 and Rad51 balances recombinational repair in Ustilago maydis
    • DOI 10.1128/MCB.26.2.678-688.2006
    • Kojic, M., Zhou, Q., Lisby, M. and Holloman, W.K. (2006) Rec2 interplay with both Brh2 and Rad51 balances recombinational repair in Ustilago maydis. Mol. Cell Biol., 26, 678-688. (Pubitemid 43089778)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.2 , pp. 678-688
    • Kojic, M.1    Zhou, Q.2    Lisby, M.3    Holloman, W.K.4
  • 63
    • 0025313211 scopus 로고
    • Architectural organization in the interphase nucleus of the protozoan Trypanosoma brucei: Location of telomeres and mini-chromosomes
    • Chung, H.M., Shea, C., Fields, S., Taub, R.N., Van der Ploeg, L.H. and Tse, D.B. (1990) Architectural organization in the interphase nucleus of the protozoan Trypanosoma brucei: location of telomeres and mini-chromosomes. EMBO J., 9, 2611-2619.
    • (1990) EMBO J , vol.9 , pp. 2611-2619
    • Chung, H.M.1    Shea, C.2    Fields, S.3    Taub, R.N.4    Van Der Ploeg, L.H.5    Tse, D.B.6


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