메뉴 건너뛰기




Volumn 6, Issue 7, 2010, Pages 1-14

TOPO3α influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; TOPOISOMERASE 3ALPHA; UNCLASSIFIED DRUG; VARIANT SURFACE GLYCOPROTEIN; BACTERIAL PROTEIN; DNA TOPOISOMERASE III; FUNGAL PROTEIN;

EID: 77957655729     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000992     Document Type: Article
Times cited : (64)

References (87)
  • 1
    • 34548396688 scopus 로고    scopus 로고
    • Analysis of the VSG gene silent archive in Trypanosoma brucei reveals that mosaic gene expression is prominent in antigenic variation and is favored by archive substructure
    • Marcello L, Barry JD (2007) Analysis of the VSG gene silent archive in Trypanosoma brucei reveals that mosaic gene expression is prominent in antigenic variation and is favored by archive substructure. Genome Res 17: 1344-1352.
    • (2007) Genome Res , vol.17 , pp. 1344-1352
    • Marcello, L.1    Barry, J.D.2
  • 2
    • 34248651591 scopus 로고    scopus 로고
    • VSGdb: A database for trypanosome variant surface glycoproteins, a large and diverse family of coiled coil proteins
    • Marcello L, Menon S, Ward P, Wilkes JM, Jones NG, et al. (2007) VSGdb: a database for trypanosome variant surface glycoproteins, a large and diverse family of coiled coil proteins. BMC Bioinformatics 8: 143.
    • (2007) BMC Bioinformatics , vol.8 , pp. 143
    • Marcello, L.1    Menon, S.2    Ward, P.3    Wilkes, J.M.4    Jones, N.G.5
  • 3
    • 23944464017 scopus 로고    scopus 로고
    • The central roles of telomeres and subtelomeres in antigenic variation in African trypanosomes
    • Horn D, Barry JD (2005) The central roles of telomeres and subtelomeres in antigenic variation in African trypanosomes. Chrom Res 13: 525-533.
    • (2005) Chrom Res , vol.13 , pp. 525-533
    • Horn, D.1    Barry, J.D.2
  • 4
    • 0035222844 scopus 로고    scopus 로고
    • Antigenic variation in trypanosomes: Enhanced phenotypic variation in a eukaryotic parasite
    • Baker JR, Muller R, RollinsonD, eds., London: Academic Press Ltd
    • Barry JD, McCulloch R (2001) Antigenic variation in trypanosomes: enhanced phenotypic variation in a eukaryotic parasite. In: Baker JR, Muller R, RollinsonD, eds. Advances in Parasitology 49. London: Academic Press Ltd. pp 1-70.
    • (2001) Advances In Parasitology 49 , pp. 1-70
    • Barry, J.D.1    McCulloch, R.2
  • 5
    • 77957658020 scopus 로고    scopus 로고
    • Antigenic variation in african trypanosomes and malaria
    • Marr J, Koumuniecki R, Nilsen TW, eds., Academic Press
    • Cross GAM (2002) Antigenic variation in african trypanosomes and malaria. In: Marr J, Koumuniecki R, Nilsen TW, eds. Mol Med Parasitol. Academic Press. pp 89-110.
    • (2002) Mol Med Parasitol , pp. 89-110
    • Cross, G.A.M.1
  • 6
    • 0024788939 scopus 로고
    • Alphaamanitin resistant transcription of protein coding genes in insect and bloodstream form Trypanosoma brucei
    • Rudenko G, Bishop D, Gottesdiener K, van der Ploeg LHT (1989) Alphaamanitin resistant transcription of protein coding genes in insect and bloodstream form Trypanosoma brucei. EMBO J 8: 4259-4263.
    • (1989) EMBO J , vol.8 , pp. 4259-4263
    • Rudenko, G.1    Bishop, D.2    Gottesdiener, K.3    van der Ploeg, L.H.T.4
  • 8
    • 18844462890 scopus 로고    scopus 로고
    • RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei
    • Gunzl A, Bruderer T, Laufer G, Schimanski B, Tu LC, et al. (2003) RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei. Eukaryot Cell 2: 542-551.
    • (2003) Eukaryot Cell , vol.2 , pp. 542-551
    • Gunzl, A.1    Bruderer, T.2    Laufer, G.3    Schimanski, B.4    Tu, L.C.5
  • 11
    • 0025041798 scopus 로고
    • The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei
    • Zomerdijk JCBM, Ouellete M, ten Asbroek ALMA, Kieft R, Bommer AMM, et al. (1990) The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei. EMBO J 9: 2791-2801.
    • (1990) EMBO J , vol.9 , pp. 2791-2801
    • Zomerdijk, J.C.B.M.1    Ouellete, M.2    Ten, A.A.L.M.A.3    Kieft, R.4    Bommer, A.M.M.5
  • 12
    • 0022474785 scopus 로고
    • Mapping of VSG genes on large expression-site chromosomes of Trypanosoma brucei separated by pulse-field gradient electrophoresis
    • Johnson PJ, Borst P (1986) Mapping of VSG genes on large expression-site chromosomes of Trypanosoma brucei separated by pulse-field gradient electrophoresis. Gene 43: 213-220.
    • (1986) Gene , vol.43 , pp. 213-220
    • Johnson, P.J.1    Borst, P.2
  • 13
    • 0020826781 scopus 로고
    • Gene conversion as a mechanism for antigenic variation in trypanosomes
    • Pays E, van Assel S, Laurent M, Darville M, Vervoort T, et al. (1983) Gene conversion as a mechanism for antigenic variation in trypanosomes. Cell 34: 371-381.
    • (1983) Cell , vol.34 , pp. 371-381
    • Pays, E.1    van Assel, S.2    Laurent, M.3    Darville, M.4    Vervoort, T.5
  • 14
    • 0021342905 scopus 로고
    • Two mechanisms of expression of a variant antigen gene of Trypanosoma brucei
    • Myler P, Nelson RG, Agabian N, Stuart K (1984) Two mechanisms of expression of a variant antigen gene of Trypanosoma brucei. Nature 309: 282-284.
    • (1984) Nature , vol.309 , pp. 282-284
    • Myler, P.1    Nelson, R.G.2    Agabian, N.3    Stuart, K.4
  • 15
    • 0023084850 scopus 로고
    • Frequent independent duplicative transpositions activate a single VSG gene
    • Lee MG-S, van der Ploeg LHT (1987) Frequent independent duplicative transpositions activate a single VSG gene. Mol Cell Biol 7: 357-364.
    • (1987) Mol Cell Biol , vol.7 , pp. 357-364
    • Lee, M.G.-S.1    van der Ploeg, L.H.T.2
  • 17
    • 0032784058 scopus 로고    scopus 로고
    • Predominance of duplicative VSG gene conversion in antigenic variation in African trypanosomes
    • Robinson NP, Burman N, Melville SE, Barry JD (1999) Predominance of duplicative VSG gene conversion in antigenic variation in African trypanosomes. Mol Cell Biol 19: 5839-5846.
    • (1999) Mol Cell Biol , vol.19 , pp. 5839-5846
    • Robinson, N.P.1    Burman, N.2    Melville, S.E.3    Barry, J.D.4
  • 18
    • 0018831573 scopus 로고
    • Novel expression-linked copies of the genes for variant surface antigens in trypanosomes
    • Hoeijmakers JHJ, Frasch ACC, Bernards A, Borst P, Cross GAM (1980) Novel expression-linked copies of the genes for variant surface antigens in trypanosomes. Nature 284: 78-80.
    • (1980) Nature , vol.284 , pp. 78-80
    • Hoeijmakers, J.H.J.1    Frasch, A.C.C.2    Bernards, A.3    Borst, P.4    Cross, G.A.M.5
  • 19
    • 0022343621 scopus 로고
    • Telomeric reciprocal recombination as a possible mechanism for antigenic variation in trypanosomes
    • Pays E, Guyaux M, Aerts D, vanMeirvenne N, Steinert M (1985) Telomeric reciprocal recombination as a possible mechanism for antigenic variation in trypanosomes. Nature 316: 562-564.
    • (1985) Nature , vol.316 , pp. 562-564
    • Pays, E.1    Guyaux, M.2    Aerts, D.3    vanMeirvenne, N.4    Steinert, M.5
  • 20
    • 25144506072 scopus 로고    scopus 로고
    • VSG switching in Trypanosoma brucei: Antigenic variation analysed using RNAi in the absence of immune selection
    • Aitcheson N, Talbot S, Shapiro J, Hughes K, Adkin C, et al. (2005) VSG switching in Trypanosoma brucei: antigenic variation analysed using RNAi in the absence of immune selection. Mol Microbiol 57: 1608-1622.
    • (2005) Mol Microbiol , vol.57 , pp. 1608-1622
    • Aitcheson, N.1    Talbot, S.2    Shapiro, J.3    Hughes, K.4    Adkin, C.5
  • 21
    • 0030249772 scopus 로고    scopus 로고
    • Telomere exchange can be an important mechanism of variant surface glycoprotein gene switching in Trypanosoma brucei
    • Rudenko G, McCulloch R, Dirksmulder A, Borst P (1996) Telomere exchange can be an important mechanism of variant surface glycoprotein gene switching in Trypanosoma brucei. Mol Biochem Parasitol 80: 65-75.
    • (1996) Mol Biochem Parasitol , vol.80 , pp. 65-75
    • Rudenko, G.1    McCulloch, R.2    Dirksmulder, A.3    Borst, P.4
  • 22
    • 0022537297 scopus 로고
    • Rapid change of the repertoire of variant surface glycoprotein genes in trypanosomes by gene duplication and deletion
    • Bernards A, van der Ploeg LHT, Gibson WC, Leegwater P, Eijgenraam F, et al. (1986) Rapid change of the repertoire of variant surface glycoprotein genes in trypanosomes by gene duplication and deletion. J Mol Biol 190: 1-10.
    • (1986) J Mol Biol , vol.190 , pp. 1-10
    • Bernards, A.1    van der, P.L.H.T.2    Gibson, W.C.3    Leegwater, P.4    Eijgenraam, F.5
  • 23
    • 29244484238 scopus 로고    scopus 로고
    • Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation
    • Proudfoot C, McCulloch R (2005) Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation. Nucl Acids Res 33: 6906-6919.
    • (2005) Nucl Acids Res , vol.33 , pp. 6906-6919
    • Proudfoot, C.1    McCulloch, R.2
  • 24
    • 0032723013 scopus 로고    scopus 로고
    • A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variation
    • McCulloch R, Barry JD (1999) A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variation. Genes Dev 13: 2875-2888.
    • (1999) Genes Dev , vol.13 , pp. 2875-2888
    • McCulloch, R.1    Barry, J.D.2
  • 25
    • 43449106468 scopus 로고    scopus 로고
    • Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination
    • Hartley CL, McCulloch R (2008) Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination. Mol Microbiol 68: 1237-1251.
    • (2008) Mol Microbiol , vol.68 , pp. 1237-1251
    • Hartley, C.L.1    McCulloch, R.2
  • 26
    • 0036276388 scopus 로고    scopus 로고
    • The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
    • D'Amours D, Jackson SP (2002) The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling. Nat Rev Mol Cell Biol 3: 317-327.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 317-327
    • D'Amours, D.1    Jackson, S.P.2
  • 27
    • 52949149420 scopus 로고    scopus 로고
    • Mre11 dimers coordinate DNA end bridging and nuclease processing in doublestrand-break repair
    • Williams RS, Moncalian G, Williams JS, Yamada Y, Limbo O, et al. (2008) Mre11 dimers coordinate DNA end bridging and nuclease processing in doublestrand-break repair. Cell 135: 97-109.
    • (2008) Cell , vol.135 , pp. 97-109
    • Williams, R.S.1    Moncalian, G.2    Williams, J.S.3    Yamada, Y.4    Limbo, O.5
  • 28
    • 52949087621 scopus 로고    scopus 로고
    • DNA repair by the MRN complex: Break it to make it
    • Kanaar R, Wyman C (2008) DNA repair by the MRN complex: break it to make it. Cell 135: 14-16.
    • (2008) Cell , vol.135 , pp. 14-16
    • Kanaar, R.1    Wyman, C.2
  • 29
    • 0036861063 scopus 로고    scopus 로고
    • Trypanosoma brucei MRE11 is nonessential but influences growth, homologous recombination and DNA doublestrand break repair
    • Tan KSW, Leal SLG, Cross GAM (2002) Trypanosoma brucei MRE11 is nonessential but influences growth, homologous recombination and DNA doublestrand break repair. Mol Biochem Parasitol 125: 11-21.
    • (2002) Mol Biochem Parasitol , vol.125 , pp. 11-21
    • Tan, K.S.W.1    Leal, S.L.G.2    Cross, G.A.M.3
  • 30
    • 0037135587 scopus 로고    scopus 로고
    • Inactivation of Mre11 does not affect VSG gene duplication mediated by homologous recombination in Trypanosoma brucei
    • Robinson NP, McCulloch R, Conway C, Browitt A, Barry JD (2002) Inactivation of Mre11 does not affect VSG gene duplication mediated by homologous recombination in Trypanosoma brucei. J Biol Chem 277: 26185-26193.
    • (2002) J Biol Chem , vol.277 , pp. 26185-26193
    • Robinson, N.P.1    McCulloch, R.2    Conway, C.3    Browitt, A.4    Barry, J.D.5
  • 31
    • 0345447604 scopus 로고    scopus 로고
    • Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast
    • Ira G, Malkova A, Liberi G, Foiani M, Haber JE (2003) Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. Cell 115: 401-411.
    • (2003) Cell , vol.115 , pp. 401-411
    • Ira, G.1    Malkova, A.2    Liberi, G.3    Foiani, M.4    Haber, J.E.5
  • 32
    • 43049162175 scopus 로고    scopus 로고
    • RecQ helicases: Guardian angels of the DNA replication fork
    • Bachrati CZ, Hickson ID (2008) RecQ helicases: guardian angels of the DNA replication fork. Chromosoma 117: 219-233.
    • (2008) Chromosoma , vol.117 , pp. 219-233
    • Bachrati, C.Z.1    Hickson, I.D.2
  • 33
    • 34547425719 scopus 로고    scopus 로고
    • Function of recQ family helicase in genome stability
    • Seki M, Tada S, Enomoto T (2006) Function of recQ family helicase in genome stability. Subcell Biochem 40: 49-73.
    • (2006) Subcell Biochem , vol.40 , pp. 49-73
    • Seki, M.1    Tada, S.2    Enomoto, T.3
  • 34
    • 33749037701 scopus 로고    scopus 로고
    • Mechanism of homologous recombination: Mediators and helicases take on regulatory functions
    • Sung P, Klein H (2006) Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nat Rev Mol Cell Biol 7: 739-750.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 739-750
    • Sung, P.1    Klein, H.2
  • 35
    • 21244434850 scopus 로고    scopus 로고
    • RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex
    • Chang M, Bellaoui M, Zhang C, Desai R, Morozov P, et al. (2005) RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J 24: 2024-2033.
    • (2005) EMBO J , vol.24 , pp. 2024-2033
    • Chang, M.1    Bellaoui, M.2    Zhang, C.3    Desai, R.4    Morozov, P.5
  • 36
    • 18944395928 scopus 로고    scopus 로고
    • Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex
    • Mullen JR, Nallaseth FS, Lan YQ, Slagle CE, Brill SJ (2005) Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex. Mol Cell Biol 25: 4476-4487.
    • (2005) Mol Cell Biol , vol.25 , pp. 4476-4487
    • Mullen, J.R.1    Nallaseth, F.S.2    Lan, Y.Q.3    Slagle, C.E.4    Brill, S.J.5
  • 37
    • 33744951596 scopus 로고    scopus 로고
    • Involvement of topoisomerase III in telomere-telomere recombination
    • Tsai HJ, Huang WH, Li TK, Tsai YL, Wu KJ, et al. (2006) Involvement of topoisomerase III in telomere-telomere recombination. J Biol Chem 281: 13717-13723.
    • (2006) J Biol Chem , vol.281 , pp. 13717-13723
    • Tsai, H.J.1    Huang, W.H.2    Li, T.K.3    Tsai, Y.L.4    Wu, K.J.5
  • 38
    • 0035936559 scopus 로고    scopus 로고
    • SGS1 is required for telomere elongation in the absence of telomerase
    • Huang PH, Pryde FE, Lester D, Maddison RL, Borts RH, et al. (2001) SGS1 is required for telomere elongation in the absence of telomerase. Curr Biol 11: 125-129.
    • (2001) Curr Biol , vol.11 , pp. 125-129
    • Huang, P.H.1    Pryde, F.E.2    Lester, D.3    Maddison, R.L.4    Borts, R.H.5
  • 39
    • 0032964641 scopus 로고    scopus 로고
    • The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells
    • Neff NF, Ellis NA, Ye TZ, Noonan J, Huang K, et al. (1999) The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells. Mol Biol Cell 10: 665-676.
    • (1999) Mol Biol Cell , vol.10 , pp. 665-676
    • Neff, N.F.1    Ellis, N.A.2    Ye, T.Z.3    Noonan, J.4    Huang, K.5
  • 40
    • 54349114671 scopus 로고    scopus 로고
    • BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome
    • Singh TR, Ali AM, Busygina V, Raynard S, Fan Q, et al. (2008) BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome. Genes Dev 22: 2856-2868.
    • (2008) Genes Dev , vol.22 , pp. 2856-2868
    • Singh, T.R.1    Ali, A.M.2    Busygina, V.3    Raynard, S.4    Fan, Q.5
  • 41
    • 54349099705 scopus 로고    scopus 로고
    • RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability
    • Xu D, Guo R, Sobeck A, Bachrati CZ, Yang J, et al. (2008) RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. Genes Dev 22: 2843-2855.
    • (2008) Genes Dev , vol.22 , pp. 2843-2855
    • Xu, D.1    Guo, R.2    Sobeck, A.3    Bachrati, C.Z.4    Yang, J.5
  • 42
    • 0029657781 scopus 로고    scopus 로고
    • SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae
    • Watt PM, Hickson ID, Borts RH, Louis EJ (1996) SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae. Genetics 144: 935-945.
    • (1996) Genetics , vol.144 , pp. 935-945
    • Watt, P.M.1    Hickson, I.D.2    Borts, R.H.3    Louis, E.J.4
  • 43
    • 0024324482 scopus 로고
    • A hyperrecombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase
    • Wallis JW, Chrebet G, Brodsky G, Rolfe M, Rothstein R (1989) A hyperrecombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase. Cell 58: 409-419.
    • (1989) Cell , vol.58 , pp. 409-419
    • Wallis, J.W.1    Chrebet, G.2    Brodsky, G.3    Rolfe, M.4    Rothstein, R.5
  • 44
    • 0347987856 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase suppresses crossing over during homologous recombination
    • Wu L, Hickson ID (2003) The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 426: 870-874.
    • (2003) Nature , vol.426 , pp. 870-874
    • Wu, L.1    Hickson, I.D.2
  • 45
    • 58149144728 scopus 로고    scopus 로고
    • Topoisomerase 3alpha and RMI1 suppress somatic crossovers and are essential for resolution of meiotic recombination intermediates in Arabidopsis thaliana
    • Hartung F, Suer S, Knoll A, Wurz-Wildersinn R, Puchta H (2008) Topoisomerase 3alpha and RMI1 suppress somatic crossovers and are essential for resolution of meiotic recombination intermediates in Arabidopsis thaliana. PLoS Genet 4: e1000285.
    • (2008) PLoS Genet , vol.4
    • Hartung, F.1    Suer, S.2    Knoll, A.3    Wurz-Wildersinn, R.4    Puchta, H.5
  • 46
    • 33746966063 scopus 로고    scopus 로고
    • Bloom helicase and DNA topoisomerase IIIalpha are involved in the dissolution of sister chromatids
    • Seki M, Nakagawa T, Seki T, Kato G, Tada S, et al. (2006) Bloom helicase and DNA topoisomerase IIIalpha are involved in the dissolution of sister chromatids. Mol Cell Biol 26: 6299-6307.
    • (2006) Mol Cell Biol , vol.26 , pp. 6299-6307
    • Seki, M.1    Nakagawa, T.2    Seki, T.3    Kato, G.4    Tada, S.5
  • 47
    • 0034923502 scopus 로고    scopus 로고
    • DNA topoisomerases: Structure, function, and mechanism
    • Champoux JJ (2001) DNA topoisomerases: structure, function, and mechanism. Annu Rev Biochem 70: 369-413.
    • (2001) Annu Rev Biochem , vol.70 , pp. 369-413
    • Champoux, J.J.1
  • 48
    • 36348958426 scopus 로고    scopus 로고
    • CRE recombinase-based positivenegative selection systems for genetic manipulation in Trypanosoma brucei
    • Scahill MD, Pastar I, Cross GA (2008) CRE recombinase-based positivenegative selection systems for genetic manipulation in Trypanosoma brucei. Mol Biochem Parasitol 157: 73-82.
    • (2008) Mol Biochem Parasitol , vol.157 , pp. 73-82
    • Scahill, M.D.1    Pastar, I.2    Cross, G.A.3
  • 49
    • 0033572760 scopus 로고    scopus 로고
    • The top3(+) gene is essential in Schizosaccharomyces pombe and the lethality associated with its loss is caused by Rad12 helicase activity
    • Maftahi M, Han CS, Langston LD, Hope JC, Zigouras N, et al. (1999) The top3(+) gene is essential in Schizosaccharomyces pombe and the lethality associated with its loss is caused by Rad12 helicase activity. Nucl Acids Res 27: 4715-4724.
    • (1999) Nucl Acids Res , vol.27 , pp. 4715-4724
    • Maftahi, M.1    Han, C.S.2    Langston, L.D.3    Hope, J.C.4    Zigouras, N.5
  • 50
    • 0032477804 scopus 로고    scopus 로고
    • Mammalian DNA topoisomerase IIIalpha is essential in early embryogenesis
    • Li W, Wang JC (1998) Mammalian DNA topoisomerase IIIalpha is essential in early embryogenesis. Proc Natl Acad Sci U S A 95: 1010-1013.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 1010-1013
    • Li, W.1    Wang, J.C.2
  • 51
    • 0035826797 scopus 로고    scopus 로고
    • Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan
    • Kwan KY, Wang JC (2001) Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan. Proc Natl Acad Sci U S A 98: 5717-5721.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5717-5721
    • Kwan, K.Y.1    Wang, J.C.2
  • 52
    • 0037150495 scopus 로고    scopus 로고
    • Inactivation of homologous recombination suppresses defects in topoisomerase III-deficient mutants
    • Oakley TJ, Goodwin A, Chakraverty RK, Hickson ID (2002) Inactivation of homologous recombination suppresses defects in topoisomerase III-deficient mutants. DNA repair 1: 463-482.
    • (2002) DNA Repair , vol.1 , pp. 463-482
    • Oakley, T.J.1    Goodwin, A.2    Chakraverty, R.K.3    Hickson, I.D.4
  • 53
    • 0037106455 scopus 로고    scopus 로고
    • Topoisomerase III is required for accurate DNA replication and chromosome segregation in Schizosaccharomyces pombe
    • Oh M, Choi IS, Park SD (2002) Topoisomerase III is required for accurate DNA replication and chromosome segregation in Schizosaccharomyces pombe. Nucl Acids Res 30: 4022-4031.
    • (2002) Nucl Acids Res , vol.30 , pp. 4022-4031
    • Oh, M.1    Choi, I.S.2    Park, S.D.3
  • 55
    • 0030911625 scopus 로고    scopus 로고
    • Manipulation of the VSG cotransposed region increases expression-site switching in Trypanosoma brucei
    • Davies KP, Carruthers VB, Cross GAM (1997) Manipulation of the VSG cotransposed region increases expression-site switching in Trypanosoma brucei. Mol Biochem Parasitol 86: 163-177.
    • (1997) Mol Biochem Parasitol , vol.86 , pp. 163-177
    • Davies, K.P.1    Carruthers, V.B.2    Cross, G.A.M.3
  • 56
    • 66149135713 scopus 로고    scopus 로고
    • A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei
    • Boothroyd CE, Dreesen O, Leonova T, Ly KI, Figueiredo LM, et al. (2009) A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei. Nature 459: 278-281.
    • (2009) Nature , vol.459 , pp. 278-281
    • Boothroyd, C.E.1    Dreesen, O.2    Leonova, T.3    Ly, K.I.4    Figueiredo, L.M.5
  • 57
    • 19944432787 scopus 로고    scopus 로고
    • Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase
    • Liberi G, Maffioletti G, Lucca C, Chiolo I, Baryshnikova A, et al. (2005) Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes Dev 19: 339-350.
    • (2005) Genes Dev , vol.19 , pp. 339-350
    • Liberi, G.1    Maffioletti, G.2    Lucca, C.3    Chiolo, I.4    Baryshnikova, A.5
  • 58
    • 33749456218 scopus 로고    scopus 로고
    • Top3 processes recombination intermediates and modulates checkpoint activity after DNA damage
    • Mankouri HW, Hickson ID (2006) Top3 processes recombination intermediates and modulates checkpoint activity after DNA damage. Mol Biol Cell 17: 4473-4483.
    • (2006) Mol Biol Cell , vol.17 , pp. 4473-4483
    • Mankouri, H.W.1    Hickson, I.D.2
  • 59
    • 0034106940 scopus 로고    scopus 로고
    • Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei
    • Vanhamme L, Poelvoorde P, Pays A, Tebabi P, Xong HV, et al. (2000) Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei. Mol Microbiol 36: 328-340.
    • (2000) Mol Microbiol , vol.36 , pp. 328-340
    • Vanhamme, L.1    Poelvoorde, P.2    Pays, A.3    Tebabi, P.4    Xong, H.V.5
  • 60
    • 0031961882 scopus 로고    scopus 로고
    • Frequent loss of the active site during variant surface glycoprotein expression site switching in vitro in Trypanosoma brucei
    • Cross M, Taylor MC, Borst P (1998) Frequent loss of the active site during variant surface glycoprotein expression site switching in vitro in Trypanosoma brucei. Mol Cell Biol 18: 198-205.
    • (1998) Mol Cell Biol , vol.18 , pp. 198-205
    • Cross, M.1    Taylor, M.C.2    Borst, P.3
  • 61
    • 0032576751 scopus 로고    scopus 로고
    • The role of transferrin-receptor variation in the host range of Trypanosoma brucei
    • Bitter W, Gerrits H, Kieft R, Borst P (1998) The role of transferrin-receptor variation in the host range of Trypanosoma brucei. Nature 391: 499-502.
    • (1998) Nature , vol.391 , pp. 499-502
    • Bitter, W.1    Gerrits, H.2    Kieft, R.3    Borst, P.4
  • 62
    • 0031053120 scopus 로고    scopus 로고
    • Gene conversions mediating antigenic variation in Trypanosoma brucei can occur in variant surface glycoprotein expression sites lacking 70-base-pair repeat sequences
    • McCulloch R, Rudenko G, Borst P (1997) Gene conversions mediating antigenic variation in Trypanosoma brucei can occur in variant surface glycoprotein expression sites lacking 70-base-pair repeat sequences. Mol Cell Biol 17: 833-843.
    • (1997) Mol Cell Biol , vol.17 , pp. 833-843
    • McCulloch, R.1    Rudenko, G.2    Borst, P.3
  • 63
    • 0029666273 scopus 로고    scopus 로고
    • TTA.TAA triplet repeats in plasmids form a non-H bonded structure
    • Ohshima K, Kang S, Larson JE, Wells RD (1996) TTA.TAA triplet repeats in plasmids form a non-H bonded structure. J Biol Chem 271: 16784-16791.
    • (1996) J Biol Chem , vol.271 , pp. 16784-16791
    • Ohshima, K.1    Kang, S.2    Larson, J.E.3    Wells, R.D.4
  • 65
    • 0022342801 scopus 로고
    • Trypanosome variant surface glycoprotein genes expressed early in infection
    • Liu AY, Michels PA, Bernards A, Borst P (1985) Trypanosome variant surface glycoprotein genes expressed early in infection. J Mol Biol 175: 383-386.
    • (1985) J Mol Biol , vol.175 , pp. 383-386
    • Liu, A.Y.1    Michels, P.A.2    Bernards, A.3    Borst, P.4
  • 66
    • 0023237403 scopus 로고
    • Coincident multiple activations of the same surface antigen gene in Trypanosoma brucei
    • Timmers HTM, de Lange T, Kooter JM, Borst P (1987) Coincident multiple activations of the same surface antigen gene in Trypanosoma brucei. J Mol Biol 184: 81-90.
    • (1987) J Mol Biol , vol.184 , pp. 81-90
    • Timmers, H.T.M.1    de Lange, T.2    Kooter, J.M.3    Borst, P.4
  • 67
    • 0024508795 scopus 로고
    • Trypanosoma brucei: Conserved sequence organization 39 to telomeric variant surface glycoprotein genes
    • Aline RF, Stuart KD (1989) Trypanosoma brucei: conserved sequence organization 39 to telomeric variant surface glycoprotein genes. Exp Parasitol 68: 57-66.
    • (1989) Exp Parasitol , vol.68 , pp. 57-66
    • Aline, R.F.1    Stuart, K.D.2
  • 68
    • 0028033989 scopus 로고
    • The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: A potential eukaryotic reverse gyrase
    • Gangloff S, McDonald JP, Bendixen C, Arthur L, Rothstein R (1994) The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol Cell Biol 14: 8391-8398.
    • (1994) Mol Cell Biol , vol.14 , pp. 8391-8398
    • Gangloff, S.1    McDonald, J.P.2    Bendixen, C.3    Arthur, L.4    Rothstein, R.5
  • 69
    • 0036812236 scopus 로고    scopus 로고
    • Mutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae
    • Shor E, Gangloff S, Wagner M, Weinstein J, Price G, et al. (2002) Mutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae. Genetics 162: 647-662.
    • (2002) Genetics , vol.162 , pp. 647-662
    • Shor, E.1    Gangloff, S.2    Wagner, M.3    Weinstein, J.4    Price, G.5
  • 70
    • 0037077206 scopus 로고    scopus 로고
    • Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomes
    • Conway C, McCulloch R, Ginger ML, Robinson NP, Browitt A, et al. (2002) Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomes. J Biol Chem 277: 21269-21277.
    • (2002) J Biol Chem , vol.277 , pp. 21269-21277
    • Conway, C.1    McCulloch, R.2    Ginger, M.L.3    Robinson, N.P.4    Browitt, A.5
  • 71
    • 0242581017 scopus 로고    scopus 로고
    • Mismatch repair regulates homologous recombination, but has little influence on antigenic variation, in Trypanosoma brucei
    • Bell JS, McCulloch R (2003) Mismatch repair regulates homologous recombination, but has little influence on antigenic variation, in Trypanosoma brucei. J Biol Chem 278: 45182-45188.
    • (2003) J Biol Chem , vol.278 , pp. 45182-45188
    • Bell, J.S.1    McCulloch, R.2
  • 72
    • 35348986443 scopus 로고    scopus 로고
    • Binding and activation of DNA topoisomerase III by the Rmi1 subunit
    • Chen CF, Brill SJ (2007) Binding and activation of DNA topoisomerase III by the Rmi1 subunit. J Biol Chem 282: 28971-28979.
    • (2007) J Biol Chem , vol.282 , pp. 28971-28979
    • Chen, C.F.1    Brill, S.J.2
  • 73
    • 0035148955 scopus 로고    scopus 로고
    • Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae
    • Mullen JR, Kaliraman V, Ibrahim SS, Brill SJ (2001) Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics 157: 103-118.
    • (2001) Genetics , vol.157 , pp. 103-118
    • Mullen, J.R.1    Kaliraman, V.2    Ibrahim, S.S.3    Brill, S.J.4
  • 74
    • 0037965787 scopus 로고    scopus 로고
    • The mechanism of Mus81-Mms4 cleavage site selection distinguishes it from the homologous endonuclease Rad1-Rad10
    • Bastin-Shanower SA, Fricke WM, Mullen JR, Brill SJ (2003) The mechanism of Mus81-Mms4 cleavage site selection distinguishes it from the homologous endonuclease Rad1-Rad10. Mol Cell Biol 23: 3487-3496.
    • (2003) Mol Cell Biol , vol.23 , pp. 3487-3496
    • Bastin-Shanower, S.A.1    Fricke, W.M.2    Mullen, J.R.3    Brill, S.J.4
  • 76
    • 52049119340 scopus 로고    scopus 로고
    • Mus81-dependent double-strand DNA breaks at in vivo-generated cruciform structures in S. cerevisiae
    • Cote AG, Lewis SM (2008) Mus81-dependent double-strand DNA breaks at in vivo-generated cruciform structures in S. cerevisiae. Mol Cell 31: 800-812.
    • (2008) Mol Cell , vol.31 , pp. 800-812
    • Cote, A.G.1    Lewis, S.M.2
  • 77
    • 56749119855 scopus 로고    scopus 로고
    • Identification of Holliday junction resolvases from humans and yeast
    • Ip SC, Rass U, Blanco MG, Flynn HR, Skehel JM, et al. (2008) Identification of Holliday junction resolvases from humans and yeast. Nature 456: 357-361.
    • (2008) Nature , vol.456 , pp. 357-361
    • Ip, S.C.1    Rass, U.2    Blanco, M.G.3    Flynn, H.R.4    Skehel, J.M.5
  • 78
    • 5644277503 scopus 로고    scopus 로고
    • Mismatch repair proteins: Key regulators of genetic recombination
    • Surtees JA, Argueso JL, Alani E (2004) Mismatch repair proteins: key regulators of genetic recombination. Cytogenet Genome Res 107: 146-159.
    • (2004) Cytogenet Genome Res , vol.107 , pp. 146-159
    • Surtees, J.A.1    Argueso, J.L.2    Alani, E.3
  • 79
    • 29144486147 scopus 로고    scopus 로고
    • Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations
    • Cobb JA, Schleker T, Rojas V, Bjergbaek L, Tercero JA, et al. (2005) Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Genes Dev 19: 3055-3069.
    • (2005) Genes Dev , vol.19 , pp. 3055-3069
    • Cobb, J.A.1    Schleker, T.2    Rojas, V.3    Bjergbaek, L.4    Tercero, J.A.5
  • 80
    • 66749175352 scopus 로고    scopus 로고
    • Transcription-associated recombination in eukaryotes: Link between transcription, replication and recombination
    • Gottipati P, Helleday T (2009) Transcription-associated recombination in eukaryotes: link between transcription, replication and recombination. Mutagenesis 24: 203-210.
    • (2009) Mutagenesis , vol.24 , pp. 203-210
    • Gottipati, P.1    Helleday, T.2
  • 81
    • 34047120661 scopus 로고    scopus 로고
    • RNA polymerase I transcription stimulates homologous recombination in Trypanosoma brucei
    • Alsford S, Horn D (2007) RNA polymerase I transcription stimulates homologous recombination in Trypanosoma brucei. Mol Biochem Parasitol 153: 77-79.
    • (2007) Mol Biochem Parasitol , vol.153 , pp. 77-79
    • Alsford, S.1    Horn, D.2
  • 82
    • 47949091926 scopus 로고    scopus 로고
    • Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei
    • Alsford S, Horn D (2008) Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei. Mol Biochem Parasitol 161: 76-79.
    • (2008) Mol Biochem Parasitol , vol.161 , pp. 76-79
    • Alsford, S.1    Horn, D.2
  • 83
    • 0036811127 scopus 로고    scopus 로고
    • Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae
    • Gonzalez-Barrera S, Garcia-Rubio M, Aguilera A (2002) Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae. Genetics 162: 603-614.
    • (2002) Genetics , vol.162 , pp. 603-614
    • Gonzalez-Barrera, S.1    Garcia-Rubio, M.2    Aguilera, A.3
  • 84
    • 37549026516 scopus 로고    scopus 로고
    • Transcriptionassociated recombination is dependent on replication in Mammalian cells
    • Gottipati P, Cassel TN, Savolainen L, Helleday T (2008) Transcriptionassociated recombination is dependent on replication in Mammalian cells. Mol Cell Biol 28: 154-164.
    • (2008) Mol Cell Biol , vol.28 , pp. 154-164
    • Gottipati, P.1    Cassel, T.N.2    Savolainen, L.3    Helleday, T.4
  • 85
    • 17144426028 scopus 로고    scopus 로고
    • Impairment of replication fork progression mediates RNA polII transcription-associated recombination
    • Prado F, Aguilera A (2005) Impairment of replication fork progression mediates RNA polII transcription-associated recombination. EMBO J 24: 1267-1276.
    • (2005) EMBO J , vol.24 , pp. 1267-1276
    • Prado, F.1    Aguilera, A.2
  • 86
    • 34547962985 scopus 로고    scopus 로고
    • Gene conversion is a convergent strategy for pathogen antigenic variation
    • Palmer GH, Brayton KA (2007) Gene conversion is a convergent strategy for pathogen antigenic variation. Trends Parasitol 23: 408-413.
    • (2007) Trends Parasitol , vol.23 , pp. 408-413
    • Palmer, G.H.1    Brayton, K.A.2
  • 87
    • 0033525524 scopus 로고    scopus 로고
    • A tightly regulated inducible expression system for dominant negative approaches in Trypanosoma brucei
    • Wirtz E, Leal S, Ochatt C, Cross GAM (1999) A tightly regulated inducible expression system for dominant negative approaches in Trypanosoma brucei. Mol Biochem Parasitol 99: 89-101.
    • (1999) Mol Biochem Parasitol , vol.99 , pp. 89-101
    • Wirtz, E.1    Leal, S.2    Ochatt, C.3    Cross, G.A.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.