Characterization of the Trypanosoma cruzi Rad51 gene and its role in recombination events associated with the parasite resistance to ionizing radiation

Molecular and Biochemical Parasitology

Volumn 149, Issue 2, 2006, Pages 191-200

  Regis da Silva, Carlos Gustavo ^a   Freitas, Jorge Marcelo ^a   Passos Silva, Danielle Gomes ^a   Furtado, Carolina ^a   Augusto Pinto, Luiz ^a   Pereira, Márcio Tadeu ^a   DaRocha, Wanderson Duarte ^a   Franco, Glória Regina ^a   Macedo, Andréa Mara ^a   Hoffmann, Jean Sebastien ^b   Cazaux, Christophe ^b   Pena, Sérgio Danilo Junho ^a   Teixeira, Santuza Maria Ribeiro ^a   Machado, Carlos Renato ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

Ionizing radiation; RAD51; Recombination; Trypanosoma cruzi

Indexed keywords

GENE PRODUCT; NEOMYCIN; RAD51 PROTEIN; RECOMBINASE;

AMASTIGOTE; ARTICLE; CHROMOSOME BAND; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GAMMA IRRADIATION; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC RECOMBINATION; GENETIC TRANSFECTION; IONIZING RADIATION; KINETICS; MAMMAL CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRYPANOSOMA CRUZI; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHO CELLS; CRICETINAE; DNA, PROTOZOAN; GAMMA RAYS; GENES, PROTOZOAN; HUMANS; MOLECULAR SEQUENCE DATA; PROTOZOAN PROTEINS; RAD51 RECOMBINASE; RADIATION TOLERANCE; RECOMBINATION, GENETIC; RNA, MESSENGER; RNA, PROTOZOAN; SEQUENCE HOMOLOGY, AMINO ACID; TRYPANOSOMA CRUZI;

MAMMALIA; PROTOZOA; TRYPANOSOMA CRUZI;

EID: 33748792822     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2006.05.012     Document Type: Article

References (34)

1. Laurent J.P., Barnabe C., Quesney V., Noel S., and Tibayrenc M. Impact of clonal evolution on the biological diversity of Trypanosoma cruzi. Parasitology 114 (1997) 213-218
2. Gaunt M.W., Yeo M., Frame I.A., et al. Mechanism of genetic exchange in American trypanosomes. Nature 421 (2003) 936-939
3. Welch D.M., and Meselson M. Evidence for the evolution of Bdelloid rotifers without sexual reproduction or genetic exchange. Science 288 (2000) 1211-1215
4. Oliveira R.P., Melo A.I., Macedo A.M., Chiari E., and Pena S.D. The population structure of Trypanosoma cruzi: expanded analysis of 54 strains using eight polymorphic CA-repeat microsatellites. Mem Inst Oswaldo Cruz 94 (1999) 65-70
5. Machado C.A., and Ayala F.J. Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi. Proc Natl Acad Sci USA 98 (2001) 7396-7401
6. El-Sayed N.M., Myler P.J., Bartholomeu D.C., et al. The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science 309 5733 (2005) 409-415
7. Kanaar R., Hoeijmakers J.H., and van Gent D.C. Molecular mechanisms of DNA double strand break repair. Trends Cell Biol 8 (1998) 483-488
8. Bhattacharyya M.K., Norris D.E., and Kumar N. Molecular players of homologous recombination in protozoan parasites: implications for generating antigenic variation. Infect Genet Evol 4 2 (2004) 91-98
9. McCulloch R., and Barry J.D. A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variation. Genes Dev 13 21 (1999) 2875-2888
10. McKean P.G., Keen J.K., Smith D.F., and Benson F.E. Identification and characterisation of a RAD51 gene from Leishmania major. Mol Biochem Parasitol 115 2 (2001) 209-216
11. Teixeira S.M., Russell D.G., Kirchhoff L.V., and Donelson J.E. A differentially expressed gene family encoding "amastin", a surface protein for Trypanosoma cruzi amastigotes. J Biol Chem 269 32 (1994) 20509-20516
12. Altschul S.F., Gish W., Miller W., Myers E.W., and Lipman D. Basic local alignment search tool. J Mol Biol 215 (1990) 403-410
13. Corpet F. Multiple sequence alignment with hierarchical clustering. Nucl Acids Res 16 (1988) 10881-10890
14. Ingham D.J., Beer S., Money S., and Hansen G. Quantitative real-time PCR assay for determining transgene copy number in transformed plants. Biotechniques 31 (2001) 132-140
15. Engman D.M., Reddy L.V., Donelson J.E., and Kirchhoff L.V. Mol Biochem Parasitol 22 2-3 (1987) 115-123
16. Cano M.I., Gruber A., Vazquez M., et al. Molecular karyotype of clone CL Brener chosen for the Trypanosoma cruzi genome project. Mol Biochem Parasitol 71 (1995) 273-278
17. DaRocha W.D., Silva R.A., Bartholomeu D.C., et al. Expression of exogenous genes in Trypanosoma cruzi: improving vectors and electroporation protocols. Parasitol Res 92 2 (2004) 113-120
18. Liang F., Han M., Romanienko P., and Jasin M. Homology-directed repair is a major double-strand break repair pathway in mammalian cells. Proc Natl Acad Sci USA 95 (1998) 5172-5177
19. Berdy J. Bleomycin-type antibiotics. In: Berdy J. (Ed). Amino acid and Peptide antibiotics (1980), CRC Press 459-497
20. Schon I., and Martens K. No slave to sex. Proc R Soc Lond B: Biol Sci 270 (2003) 827-833
21. Thayer M.M., Ahern H., Xing D., Cunningham R.P., and Tainer J.A. Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure. EMBO J 14 (1995) 4108-4120
22. Aravind L., Walker D.R., and Koonin E.V. Conserved domains in DNA repair proteins and evolution of repair systems. Nucl Acids Res 27 (1999) 1223-1242
23. Iyer L.M., Leipe D.D., Koonin E.V., and Aravind L. Evolutionary history and higher order classification of AAA+ ATPases. J Struct Biol 146 (2004) 11-31
24. Machado C.R., Augusto-Pinto L., McCulloch R., and Teixeira S.M. DNA metabolism and genetic diversity in trypanosomes. Mutat Res 612 (2006) 40-57
25. Takeda G.K., Campos R., Kieffer J., et al. Effect of gamma rays on blood forms of Trypanosoma cruzi. Experimental study in mice. Rev Inst Med Trop Sao Paulo 28 (1986) 15-18
26. Bennett C.B., Lewis L.K., Karthikeyan G., et al. Genes required for ionizing radiation resistance in yeast. Nat Genet 29 4 (2001) 426-434
27. Quint R.M., Solar S., and Stan-Lotter H. Radiation sensitivity of N. pharaonis in comparison with E. coli K12 strains. Radiat Environ Biophys 41 2 (2002) 145-148
28. Jiang C.Z., Yen C.N., Cronin K., Mitchellt D., and Britt A.B. UV- and gamma-radiation sensitive mutants of Arabidopsis thaliana. Genetics 147 3 (1997) 1401-1409
29. Geoghegan D.S., Skinner-Adams T., and Davis T.M. Plasmodium falciparum: isolate-specific radiosensitivity. Exp Parasitol 99 2 (2001) 108-110
30. Yonetani Y., Hochegger H., Sonoda E., et al. Differential and collaborative actions of Rad51 paralog proteins in cellular response to DNA damage. Nucl Acids Res 33 14 (2005) 4544-4552
31. Takata M., Sasaki M.S., Tachiiri S., et al. Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs. Mol Cell Biol 21 8 (2001) 2858-2866
32. Liu Y., Zhou J., Omelchenko M.V., et al. Transcriptome dynamics of Deinococcus radiodurans recovering from ionizing radiation. Proc Natl Acad Sci USA 100 7 (2003) 4191-4196
33. Proudfoot C., and McCulloch R. Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation. Nucl Acids Res 33 21 (2005) 6906-6919
34. Kawabata M., Kawabata T., and Nishibori M. Role of recA/RAD51 family proteins in mammals. Acta Med Okayama 59 1 (2005) 1-9