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Volumn 368, Issue 1-2, 2013, Pages 120-128

Nuclear receptors, bile acids and cholesterol homeostasis series - Bile acids and pregnancy

Author keywords

Bile acid; Fetoplacental unit; Intrahepatic cholestasis of pregnancy; Pregnancy

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; CHOLESTEROL; FARNESOID X RECEPTOR; PLACEBO; URSODEOXYCHOLIC ACID;

EID: 84875241809     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.10.027     Document Type: Review
Times cited : (19)

References (132)
  • 7
    • 27644526115 scopus 로고    scopus 로고
    • Biology of a novel organic solute and steroid transporter, OSTalpha-OSTbeta
    • Ballatori N. Biology of a novel organic solute and steroid transporter, OSTalpha-OSTbeta. Exp. Biol. Med. (Maywood.) 2005, 230:689-698.
    • (2005) Exp. Biol. Med. (Maywood.) , vol.230 , pp. 689-698
    • Ballatori, N.1
  • 8
    • 33744920572 scopus 로고    scopus 로고
    • Drug insight: mechanisms and sites of action of ursodeoxycholic acid in cholestasis
    • Beuers U. Drug insight: mechanisms and sites of action of ursodeoxycholic acid in cholestasis. Nat. Clin. Pract. Gastroenterol. Hepatol. 2006, 3:318-328.
    • (2006) Nat. Clin. Pract. Gastroenterol. Hepatol. , vol.3 , pp. 318-328
    • Beuers, U.1
  • 10
    • 77957949650 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17beta-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C
    • Boaglio A.C., Zucchetti A.E., Sanchez Pozzi E.J., Pellegrino J.M., Ochoa J.E., Mottino A.D., Vore M., Crocenzi F.A., Roma M.G. Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17beta-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C. Hepatology 2010, 52:1465-1476.
    • (2010) Hepatology , vol.52 , pp. 1465-1476
    • Boaglio, A.C.1    Zucchetti, A.E.2    Sanchez Pozzi, E.J.3    Pellegrino, J.M.4    Ochoa, J.E.5    Mottino, A.D.6    Vore, M.7    Crocenzi, F.A.8    Roma, M.G.9
  • 11
    • 13644266845 scopus 로고    scopus 로고
    • Novel pathways of bile acid metabolism involving CYP3A4
    • Bodin K., Lindbom U., Diczfalusy U. Novel pathways of bile acid metabolism involving CYP3A4. Biochim. Biophys. Acta 2005, 1687:84-93.
    • (2005) Biochim. Biophys. Acta , vol.1687 , pp. 84-93
    • Bodin, K.1    Lindbom, U.2    Diczfalusy, U.3
  • 12
    • 0344133016 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy: changes in maternal-fetal bile acid balance and improvement by ursodeoxycholic acid
    • Brites D. Intrahepatic cholestasis of pregnancy: changes in maternal-fetal bile acid balance and improvement by ursodeoxycholic acid. Ann. Hepatol. 2002, 1:20-28.
    • (2002) Ann. Hepatol. , vol.1 , pp. 20-28
    • Brites, D.1
  • 13
    • 0031952407 scopus 로고    scopus 로고
    • Correction of maternal serum bile acid profile during ursodeoxycholic acid therapy in cholestasis of pregnancy
    • Brites D., Rodrigues C.M., Oliveira N., Cardoso M., Graca L.M. Correction of maternal serum bile acid profile during ursodeoxycholic acid therapy in cholestasis of pregnancy. J. Hepatol. 1998, 28:91-98.
    • (1998) J. Hepatol. , vol.28 , pp. 91-98
    • Brites, D.1    Rodrigues, C.M.2    Oliveira, N.3    Cardoso, M.4    Graca, L.M.5
  • 16
    • 75749126926 scopus 로고    scopus 로고
    • The influence of common gene variants of the xenobiotic receptor (PXR) in genetic susceptibility to intrahepatic cholestasis of pregnancy
    • Castano G., Burgueno A., Fernandez G.T., Pirola C.J., Sookoian S. The influence of common gene variants of the xenobiotic receptor (PXR) in genetic susceptibility to intrahepatic cholestasis of pregnancy. Aliment. Pharmacol. Ther. 2010, 31:583-592.
    • (2010) Aliment. Pharmacol. Ther. , vol.31 , pp. 583-592
    • Castano, G.1    Burgueno, A.2    Fernandez, G.T.3    Pirola, C.J.4    Sookoian, S.5
  • 18
    • 33645068867 scopus 로고    scopus 로고
    • Expression and functional activity of breast cancer resistance protein (BCRP, ABCG2) transporter in the human choriocarcinoma cell line BeWo
    • Ceckova M., Libra A., Pavek P., Nachtigal P., Brabec M., Fuchs R., Staud F. Expression and functional activity of breast cancer resistance protein (BCRP, ABCG2) transporter in the human choriocarcinoma cell line BeWo. Clin. Exp. Pharmacol. Physiol. 2006, 33:58-65.
    • (2006) Clin. Exp. Pharmacol. Physiol. , vol.33 , pp. 58-65
    • Ceckova, M.1    Libra, A.2    Pavek, P.3    Nachtigal, P.4    Brabec, M.5    Fuchs, R.6    Staud, F.7
  • 19
    • 84862665365 scopus 로고    scopus 로고
    • Ursodeoxycholic acid versus placebo, and early term delivery versus expectant management, in women with intrahepatic cholestasis of pregnancy: semifactorial randomised clinical trial
    • Chappell L.C., Gurung V., Seed P.T., Chambers J., Williamson C., Thornton J.G. Ursodeoxycholic acid versus placebo, and early term delivery versus expectant management, in women with intrahepatic cholestasis of pregnancy: semifactorial randomised clinical trial. BMJ 2012, 344:e3799.
    • (2012) BMJ , vol.344
    • Chappell, L.C.1    Gurung, V.2    Seed, P.T.3    Chambers, J.4    Williamson, C.5    Thornton, J.G.6
  • 20
    • 70349430938 scopus 로고    scopus 로고
    • Bile acids: regulation of synthesis
    • Chiang J.Y. Bile acids: regulation of synthesis. J. Lipid Res. 2009, 50:1955-1966.
    • (2009) J. Lipid Res. , vol.50 , pp. 1955-1966
    • Chiang, J.Y.1
  • 21
    • 0036799064 scopus 로고    scopus 로고
    • Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption
    • Collier A.C., Tingle M.D., Paxton J.W., Mitchell M.D., Keelan J.A. Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption. Hum. Reprod. 2002, 17:2564-2572.
    • (2002) Hum. Reprod. , vol.17 , pp. 2564-2572
    • Collier, A.C.1    Tingle, M.D.2    Paxton, J.W.3    Mitchell, M.D.4    Keelan, J.A.5
  • 23
    • 0019151066 scopus 로고
    • Morphological study of placental terminal villi in intrahepatic cholestasis of pregnancy: histochemistry, light and electron microscopy
    • Costoya A.L., Leontic E.A., Rosenberg H.G., Delgado M.A. Morphological study of placental terminal villi in intrahepatic cholestasis of pregnancy: histochemistry, light and electron microscopy. Placenta 1980, 1:361-368.
    • (1980) Placenta , vol.1 , pp. 361-368
    • Costoya, A.L.1    Leontic, E.A.2    Rosenberg, H.G.3    Delgado, M.A.4
  • 28
    • 67651191461 scopus 로고    scopus 로고
    • The molecular genetics of intrahepatic cholestasis of pregnancy
    • Dixon P.H., Williamson C. The molecular genetics of intrahepatic cholestasis of pregnancy. Obstet. Med. 2008, 1:65-71.
    • (2008) Obstet. Med. , vol.1 , pp. 65-71
    • Dixon, P.H.1    Williamson, C.2
  • 30
    • 0027515236 scopus 로고
    • +/taurocholate cotransport in isolated hepatocytes from postpartum rats and ovariectomized rats
    • +/taurocholate cotransport in isolated hepatocytes from postpartum rats and ovariectomized rats. J. Pharmacol. Exp. Ther. 1993, 267:82-87.
    • (1993) J. Pharmacol. Exp. Ther. , vol.267 , pp. 82-87
    • Ganguly, T.1    Hyde, J.F.2    Vore, M.3
  • 31
  • 33
    • 0035914079 scopus 로고    scopus 로고
    • Biochemical characterization and tissue distribution of human SULT2B1
    • Geese W.J., Raftogianis R.B. Biochemical characterization and tissue distribution of human SULT2B1. Biochem. Biophys. Res. Commun. 2001, 288:280-289.
    • (2001) Biochem. Biophys. Res. Commun. , vol.288 , pp. 280-289
    • Geese, W.J.1    Raftogianis, R.B.2
  • 36
    • 32944463445 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy: a randomized controlled trial comparing dexamethasone and ursodeoxycholic acid
    • Glantz A., Marschall H.U., Lammert F., Mattsson L.A. Intrahepatic cholestasis of pregnancy: a randomized controlled trial comparing dexamethasone and ursodeoxycholic acid. Hepatology 2005, 42:1399-1405.
    • (2005) Hepatology , vol.42 , pp. 1399-1405
    • Glantz, A.1    Marschall, H.U.2    Lammert, F.3    Mattsson, L.A.4
  • 37
    • 4043111379 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy: relationships between bile acid levels and fetal complication rates
    • Glantz A., Marschall H.U., Mattsson L.A. Intrahepatic cholestasis of pregnancy: relationships between bile acid levels and fetal complication rates. Hepatology 2004, 40:467-474.
    • (2004) Hepatology , vol.40 , pp. 467-474
    • Glantz, A.1    Marschall, H.U.2    Mattsson, L.A.3
  • 38
    • 39549090422 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy: amelioration of pruritus by UDCA is associated with decreased progesterone disulphates in urine
    • Glantz A., Reilly S.J., Benthin L., Lammert F., Mattsson L.A., Marschall H.U. Intrahepatic cholestasis of pregnancy: amelioration of pruritus by UDCA is associated with decreased progesterone disulphates in urine. Hepatology 2008, 47:544-551.
    • (2008) Hepatology , vol.47 , pp. 544-551
    • Glantz, A.1    Reilly, S.J.2    Benthin, L.3    Lammert, F.4    Mattsson, L.A.5    Marschall, H.U.6
  • 39
    • 1242317691 scopus 로고    scopus 로고
    • The sodium bile salt cotransport family SLC10
    • Hagenbuch B., Dawson P. The sodium bile salt cotransport family SLC10. Pflugers Arch. 2004, 447:566-570.
    • (2004) Pflugers Arch. , vol.447 , pp. 566-570
    • Hagenbuch, B.1    Dawson, P.2
  • 40
    • 1242272736 scopus 로고    scopus 로고
    • Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties
    • Hagenbuch B., Meier P.J. Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch. 2004, 447:653-665.
    • (2004) Pflugers Arch. , vol.447 , pp. 653-665
    • Hagenbuch, B.1    Meier, P.J.2
  • 42
    • 2542597642 scopus 로고    scopus 로고
    • Different subcellular localization of sulphotransferase 2B1b in human placenta and prostate
    • He D., Meloche C.A., Dumas N.A., Frost A.R., Falany C.N. Different subcellular localization of sulphotransferase 2B1b in human placenta and prostate. Biochem. J. 2004, 379:533-540.
    • (2004) Biochem. J. , vol.379 , pp. 533-540
    • He, D.1    Meloche, C.A.2    Dumas, N.A.3    Frost, A.R.4    Falany, C.N.5
  • 43
    • 0020586927 scopus 로고
    • Serum bile acids in the early diagnosis of intrahepatic cholestasis of pregnancy
    • Heikkinen J. Serum bile acids in the early diagnosis of intrahepatic cholestasis of pregnancy. Obstet. Gynecol. 1983, 61:581-587.
    • (1983) Obstet. Gynecol. , vol.61 , pp. 581-587
    • Heikkinen, J.1
  • 44
    • 0019424706 scopus 로고
    • Changes in serum bile acid concentrations during normal pregnancy, in patients with intrahepatic cholestasis of pregnancy and in pregnant women with itching
    • Heikkinen J., Maentausta O., Ylostalo P., Janne O. Changes in serum bile acid concentrations during normal pregnancy, in patients with intrahepatic cholestasis of pregnancy and in pregnant women with itching. Br. J. Obstet. Gynaecol. 1981, 88:240-245.
    • (1981) Br. J. Obstet. Gynaecol. , vol.88 , pp. 240-245
    • Heikkinen, J.1    Maentausta, O.2    Ylostalo, P.3    Janne, O.4
  • 45
    • 0023024949 scopus 로고
    • Maximal response to oxytocin of the isolated myometrium from pregnant patients with intrahepatic cholestasis
    • Israel E.J., Guzman M.L., Campos G.A. Maximal response to oxytocin of the isolated myometrium from pregnant patients with intrahepatic cholestasis. Acta Obstet. Gynecol. Scand. 1986, 65:581-582.
    • (1986) Acta Obstet. Gynecol. Scand. , vol.65 , pp. 581-582
    • Israel, E.J.1    Guzman, M.L.2    Campos, G.A.3
  • 47
    • 33645983221 scopus 로고    scopus 로고
    • LXRS and FXR: the yin and yang of cholesterol and fat metabolism
    • Kalaany N.Y., Mangelsdorf D.J. LXRS and FXR: the yin and yang of cholesterol and fat metabolism. Annu. Rev. Physiol. 2006, 68:159-191.
    • (2006) Annu. Rev. Physiol. , vol.68 , pp. 159-191
    • Kalaany, N.Y.1    Mangelsdorf, D.J.2
  • 48
    • 13844299425 scopus 로고    scopus 로고
    • Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1
    • Katsuma S., Hirasawa A., Tsujimoto G. Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1. Biochem. Biophys. Res. Commun. 2005, 329:386-390.
    • (2005) Biochem. Biophys. Res. Commun. , vol.329 , pp. 386-390
    • Katsuma, S.1    Hirasawa, A.2    Tsujimoto, G.3
  • 49
    • 0023136921 scopus 로고
    • Low serum selenium concentration and glutathione peroxidase activity in intrahepatic cholestasis of pregnancy
    • Kauppila A., Korpela H., Makila U.M., Yrjanheikki E. Low serum selenium concentration and glutathione peroxidase activity in intrahepatic cholestasis of pregnancy. Br. Med. J. (Clin. Res. Ed.) 1987, 294:150-152.
    • (1987) Br. Med. J. (Clin. Res. Ed.) , vol.294 , pp. 150-152
    • Kauppila, A.1    Korpela, H.2    Makila, U.M.3    Yrjanheikki, E.4
  • 50
    • 33746537974 scopus 로고    scopus 로고
    • Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy
    • Keitel V., Vogt C., Haussinger D., Kubitz R. Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy. Gastroenterology 2006, 131:624-629.
    • (2006) Gastroenterology , vol.131 , pp. 624-629
    • Keitel, V.1    Vogt, C.2    Haussinger, D.3    Kubitz, R.4
  • 54
    • 77950678813 scopus 로고    scopus 로고
    • The c.504T>C (p.Asn168Asn) polymorphism in the ABCB4 gene as a predisposing factor for intrahepatic cholestasis of pregnancy in Greece
    • Kitsiou-Tzeli S., Traeger-Synodinos J., Giannatou E., Kaminopetros P., Roma E., Makrythanasis P., Tsezou A. The c.504T>C (p.Asn168Asn) polymorphism in the ABCB4 gene as a predisposing factor for intrahepatic cholestasis of pregnancy in Greece. Liver Int. 2010, 30:489-491.
    • (2010) Liver Int. , vol.30 , pp. 489-491
    • Kitsiou-Tzeli, S.1    Traeger-Synodinos, J.2    Giannatou, E.3    Kaminopetros, P.4    Roma, E.5    Makrythanasis, P.6    Tsezou, A.7
  • 55
    • 1242295185 scopus 로고    scopus 로고
    • The SLC22 drug transporter family
    • Koepsell H., Endou H. The SLC22 drug transporter family. Pflugers Arch. 2004, 447:666-676.
    • (2004) Pflugers Arch. , vol.447 , pp. 666-676
    • Koepsell, H.1    Endou, H.2
  • 56
    • 24144477934 scopus 로고    scopus 로고
    • Efficacy and safety of ursodeoxycholic acid versus cholestyramine in intrahepatic cholestasis of pregnancy
    • Kondrackiene J., Beuers U., Kupcinskas L. Efficacy and safety of ursodeoxycholic acid versus cholestyramine in intrahepatic cholestasis of pregnancy. Gastroenterology 2005, 129:894-901.
    • (2005) Gastroenterology , vol.129 , pp. 894-901
    • Kondrackiene, J.1    Beuers, U.2    Kupcinskas, L.3
  • 59
    • 0016716534 scopus 로고
    • Determination of serum bile acids by glass capillary gas-liquid chromatography
    • Laatikainen T., Hesso A. Determination of serum bile acids by glass capillary gas-liquid chromatography. Clin. Chim. Acta 1975, 64:63-68.
    • (1975) Clin. Chim. Acta , vol.64 , pp. 63-68
    • Laatikainen, T.1    Hesso, A.2
  • 60
    • 0017707182 scopus 로고
    • Serum bile acids in cholestasis of pregnancy
    • Laatikainen T., Ikonen E. Serum bile acids in cholestasis of pregnancy. Obstet. Gynecol. 1977, 50:313-318.
    • (1977) Obstet. Gynecol. , vol.50 , pp. 313-318
    • Laatikainen, T.1    Ikonen, E.2
  • 61
    • 0015693101 scopus 로고
    • Excertion of progesterone metabolites in urine and bile of pregnant women with intrahepatic cholestasis
    • Laatikainen T., Karjalainen O. Excertion of progesterone metabolites in urine and bile of pregnant women with intrahepatic cholestasis. J. Steroid Biochem. 1973, 4:641-648.
    • (1973) J. Steroid Biochem. , vol.4 , pp. 641-648
    • Laatikainen, T.1    Karjalainen, O.2
  • 62
    • 0017883294 scopus 로고
    • Biliary bile acids in uncomplicated pregnancy and in cholestasis of pregnancy
    • Laatikainen T., Lehtonen P., Hesso A. Biliary bile acids in uncomplicated pregnancy and in cholestasis of pregnancy. Clin. Chim. Acta 1978, 85:145-150.
    • (1978) Clin. Chim. Acta , vol.85 , pp. 145-150
    • Laatikainen, T.1    Lehtonen, P.2    Hesso, A.3
  • 63
    • 0021359851 scopus 로고
    • Maternal serum bile acid levels and fetal distress in cholestasis of pregnancy
    • Laatikainen T., Tulenheimo A. Maternal serum bile acid levels and fetal distress in cholestasis of pregnancy. Int. J. Gynaecol. Obstet. 1984, 22:91-94.
    • (1984) Int. J. Gynaecol. Obstet. , vol.22 , pp. 91-94
    • Laatikainen, T.1    Tulenheimo, A.2
  • 64
    • 0016785579 scopus 로고
    • Fetal bile acid levels in pregnancies complicated by maternal intrahepatic cholestasis
    • Laatikainen T.J. Fetal bile acid levels in pregnancies complicated by maternal intrahepatic cholestasis. Am. J. Obstet. Gynecol. 1975, 122:852-856.
    • (1975) Am. J. Obstet. Gynecol. , vol.122 , pp. 852-856
    • Laatikainen, T.J.1
  • 68
    • 0022450213 scopus 로고
    • Serum bile acid concentrations during pregnancy and their relationship to obstetric cholestasis
    • Lunzer M., Barnes P., Byth K., O'Halloran M. Serum bile acid concentrations during pregnancy and their relationship to obstetric cholestasis. Gastroenterology 1986, 91:825-829.
    • (1986) Gastroenterology , vol.91 , pp. 825-829
    • Lunzer, M.1    Barnes, P.2    Byth, K.3    O'Halloran, M.4
  • 71
    • 40949141985 scopus 로고    scopus 로고
    • Molecular bases of the fetal liver-placenta-maternal liver excretory pathway for cholephilic compounds
    • Marin J.J., Macias R.I., Briz O., Perez M.J., Blazquez A.G., Arrese M., Serrano M.A. Molecular bases of the fetal liver-placenta-maternal liver excretory pathway for cholephilic compounds. Liver Int. 2008, 28:435-454.
    • (2008) Liver Int. , vol.28 , pp. 435-454
    • Marin, J.J.1    Macias, R.I.2    Briz, O.3    Perez, M.J.4    Blazquez, A.G.5    Arrese, M.6    Serrano, M.A.7
  • 72
    • 0025052230 scopus 로고
    • Bile acid transport by basal membrane vesicles of human term placental trophoblast
    • Marin J.J., Serrano M.A., El-Mir M.Y., Eleno N., Boyd C.A. Bile acid transport by basal membrane vesicles of human term placental trophoblast. Gastroenterology 1990, 99:1431-1438.
    • (1990) Gastroenterology , vol.99 , pp. 1431-1438
    • Marin, J.J.1    Serrano, M.A.2    El-Mir, M.Y.3    Eleno, N.4    Boyd, C.A.5
  • 73
    • 79953317272 scopus 로고    scopus 로고
    • ABC multidrug transporters: target for modulation of drug pharmacokinetics and drug-drug interactions
    • Marquez B., Van B.F. ABC multidrug transporters: target for modulation of drug pharmacokinetics and drug-drug interactions. Curr. Drug Targets 2011, 12:600-620.
    • (2011) Curr. Drug Targets , vol.12 , pp. 600-620
    • Marquez, B.1    Van, B.F.2
  • 76
    • 39849096025 scopus 로고    scopus 로고
    • Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump
    • Meier Y., Zodan T., Lang C., Zimmermann R., Kullak-Ublick G.A., Meier P.J., Stieger B., Pauli-Magnus C. Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump. World J. Gastroenterol. 2008, 14:38-45.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 38-45
    • Meier, Y.1    Zodan, T.2    Lang, C.3    Zimmermann, R.4    Kullak-Ublick, G.A.5    Meier, P.J.6    Stieger, B.7    Pauli-Magnus, C.8
  • 77
    • 0030663220 scopus 로고    scopus 로고
    • Progesterone metabolites and bile acids in serum of patients with intrahepatic cholestasis of pregnancy: effect of ursodeoxycholic acid therapy
    • Meng L.J., Reyes H., Axelson M., Palma J., Hernandez I., Ribalta J., Sjovall J. Progesterone metabolites and bile acids in serum of patients with intrahepatic cholestasis of pregnancy: effect of ursodeoxycholic acid therapy. Hepatology 1997, 26:1573-1579.
    • (1997) Hepatology , vol.26 , pp. 1573-1579
    • Meng, L.J.1    Reyes, H.2    Axelson, M.3    Palma, J.4    Hernandez, I.5    Ribalta, J.6    Sjovall, J.7
  • 78
    • 0030734641 scopus 로고    scopus 로고
    • Effects of ursodeoxycholic acid on conjugated bile acids and progesterone metabolites in serum and urine of patients with intrahepatic cholestasis of pregnancy
    • Meng L.J., Reyes H., Palma J., Hernandez I., Ribalta J., Sjovall J. Effects of ursodeoxycholic acid on conjugated bile acids and progesterone metabolites in serum and urine of patients with intrahepatic cholestasis of pregnancy. J. Hepatol. 1997, 27:1029-1040.
    • (1997) J. Hepatol. , vol.27 , pp. 1029-1040
    • Meng, L.J.1    Reyes, H.2    Palma, J.3    Hernandez, I.4    Ribalta, J.5    Sjovall, J.6
  • 79
    • 0030759322 scopus 로고    scopus 로고
    • Profiles of bile acids and progesterone metabolites in the urine and serum of women with intrahepatic cholestasis of pregnancy
    • Meng L.J., Reyes H., Palma J., Hernandez I., Ribalta J., Sjovall J. Profiles of bile acids and progesterone metabolites in the urine and serum of women with intrahepatic cholestasis of pregnancy. J. Hepatol. 1997, 27:346-357.
    • (1997) J. Hepatol. , vol.27 , pp. 346-357
    • Meng, L.J.1    Reyes, H.2    Palma, J.3    Hernandez, I.4    Ribalta, J.5    Sjovall, J.6
  • 86
    • 0031758184 scopus 로고    scopus 로고
    • A randomised placebo-controlled trial of ursodeoxycholic acid and S-adenosylmethionine in the treatment of intrahepatic cholestasis of pregnancy
    • Nicastri P.L., Diaferia A., Tartagni M., Loizzi P., Fanelli M. A randomised placebo-controlled trial of ursodeoxycholic acid and S-adenosylmethionine in the treatment of intrahepatic cholestasis of pregnancy. Br. J. Obstet. Gynaecol. 1998, 105:1205-1207.
    • (1998) Br. J. Obstet. Gynaecol. , vol.105 , pp. 1205-1207
    • Nicastri, P.L.1    Diaferia, A.2    Tartagni, M.3    Loizzi, P.4    Fanelli, M.5
  • 87
    • 33846706434 scopus 로고    scopus 로고
    • The apical conjugate efflux pump ABCC2 (MRP2)
    • Nies A.T., Keppler D. The apical conjugate efflux pump ABCC2 (MRP2). Pflugers Arch. 2007, 453:643-659.
    • (2007) Pflugers Arch. , vol.453 , pp. 643-659
    • Nies, A.T.1    Keppler, D.2
  • 92
    • 84875257666 scopus 로고    scopus 로고
    • Nuclear receptor-driven alterations in bile acid and lipid metabolic pathways during gestation
    • Papacleovoulou G., Abu-Hayyeh S., Williamson C. Nuclear receptor-driven alterations in bile acid and lipid metabolic pathways during gestation. Biochim. Biophys. Acta 2010.
    • (2010) Biochim. Biophys. Acta
    • Papacleovoulou, G.1    Abu-Hayyeh, S.2    Williamson, C.3
  • 97
    • 1642338852 scopus 로고    scopus 로고
    • Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease
    • (vi)
    • Paumgartner G., Beuers U. Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease. Clin. Liver Dis. 2004, 8:67-81. (vi).
    • (2004) Clin. Liver Dis. , vol.8 , pp. 67-81
    • Paumgartner, G.1    Beuers, U.2
  • 98
    • 27944467436 scopus 로고    scopus 로고
    • Maternal cholestasis induces placental oxidative stress and apoptosis. Protective effect ursodeoxycholic acid
    • Perez M.J., Macias R.I., Marin J.J. Maternal cholestasis induces placental oxidative stress and apoptosis. Protective effect ursodeoxycholic acid. Placenta 2006, 27:34-41.
    • (2006) Placenta , vol.27 , pp. 34-41
    • Perez, M.J.1    Macias, R.I.2    Marin, J.J.3
  • 99
    • 39649093658 scopus 로고    scopus 로고
    • Sex hormones and bile acids in intrahepatic cholestasis of pregnancy
    • Reyes H. Sex hormones and bile acids in intrahepatic cholestasis of pregnancy. Hepatology 2008, 47:376-379.
    • (2008) Hepatology , vol.47 , pp. 376-379
    • Reyes, H.1
  • 100
    • 0342803591 scopus 로고    scopus 로고
    • Selenium, zinc and copper plasma levels in intrahepatic cholestasis of pregnancy, in normal pregnancies and in healthy individuals, in Chile
    • Reyes H., Baez M.E., Gonzalez M.C., Hernandez I., Palma J., Ribalta J., Sandoval L., Zapata R. Selenium, zinc and copper plasma levels in intrahepatic cholestasis of pregnancy, in normal pregnancies and in healthy individuals, in Chile. J. Hepatol. 2000, 32:542-549.
    • (2000) J. Hepatol. , vol.32 , pp. 542-549
    • Reyes, H.1    Baez, M.E.2    Gonzalez, M.C.3    Hernandez, I.4    Palma, J.5    Ribalta, J.6    Sandoval, L.7    Zapata, R.8
  • 101
    • 0027366353 scopus 로고
    • Intrahepatic cholestasis of pregnancy: an estrogen-related disease
    • Reyes H., Simon F.R. Intrahepatic cholestasis of pregnancy: an estrogen-related disease. Semin. Liver Dis. 1993, 13:289-301.
    • (1993) Semin. Liver Dis. , vol.13 , pp. 289-301
    • Reyes, H.1    Simon, F.R.2
  • 102
    • 1642586761 scopus 로고    scopus 로고
    • Bile acids and progesterone metabolites in intrahepatic cholestasis of pregnancy
    • Reyes H., Sjovall J. Bile acids and progesterone metabolites in intrahepatic cholestasis of pregnancy. Ann. Med. 2000, 32:94-106.
    • (2000) Ann. Med. , vol.32 , pp. 94-106
    • Reyes, H.1    Sjovall, J.2
  • 103
    • 0031950282 scopus 로고    scopus 로고
    • Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production
    • Rodrigues C.M., Fan G., Wong P.Y., Kren B.T., Steer C.J. Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production. Mol. Med. 1998, 4:165-178.
    • (1998) Mol. Med. , vol.4 , pp. 165-178
    • Rodrigues, C.M.1    Fan, G.2    Wong, P.Y.3    Kren, B.T.4    Steer, C.J.5
  • 104
    • 33645982862 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy as an indicator of liver and biliary diseases: a population-based study
    • Ropponen A., Sund R., Riikonen S., Ylikorkala O., Aittomaki K. Intrahepatic cholestasis of pregnancy as an indicator of liver and biliary diseases: a population-based study. Hepatology 2006, 43:723-728.
    • (2006) Hepatology , vol.43 , pp. 723-728
    • Ropponen, A.1    Sund, R.2    Riikonen, S.3    Ylikorkala, O.4    Aittomaki, K.5
  • 106
    • 0032079866 scopus 로고    scopus 로고
    • Beneficial effect of ursodeoxycholic acid on alterations induced by cholestasis of pregnancy in bile acid transport across the human placenta
    • Serrano M.A., Brites D., Larena M.G., Monte M.J., Bravo M.P., Oliveira N., Marin J.J. Beneficial effect of ursodeoxycholic acid on alterations induced by cholestasis of pregnancy in bile acid transport across the human placenta. J. Hepatol. 1998, 28:829-839.
    • (1998) J. Hepatol. , vol.28 , pp. 829-839
    • Serrano, M.A.1    Brites, D.2    Larena, M.G.3    Monte, M.J.4    Bravo, M.P.5    Oliveira, N.6    Marin, J.J.7
  • 108
    • 0023744184 scopus 로고
    • Hepatic bile acid metabolism during early development revealed from the analysis of human fetal gallbladder bile
    • Setchell K.D., Dumaswala R., Colombo C., Ronchi M. Hepatic bile acid metabolism during early development revealed from the analysis of human fetal gallbladder bile. J. Biol. Chem. 1988, 263:16637-16644.
    • (1988) J. Biol. Chem. , vol.263 , pp. 16637-16644
    • Setchell, K.D.1    Dumaswala, R.2    Colombo, C.3    Ronchi, M.4
  • 112
    • 0014899033 scopus 로고
    • Steroid sulphates in plasma from pregnant women with pruritus and elevated plasma bile acid levels
    • Sjovall J., Sjovall K. Steroid sulphates in plasma from pregnant women with pruritus and elevated plasma bile acid levels. Ann. Clin. Res. 1970, 2:321-337.
    • (1970) Ann. Clin. Res. , vol.2 , pp. 321-337
    • Sjovall, J.1    Sjovall, K.2
  • 113
    • 0013882594 scopus 로고
    • Serum bile acid levels in pregnancy with pruritus (bile acids and steroids 158)
    • Sjovall K., Sjovall J. Serum bile acid levels in pregnancy with pruritus (bile acids and steroids 158). Clin. Chim. Acta 1966, 13:207-211.
    • (1966) Clin. Chim. Acta , vol.13 , pp. 207-211
    • Sjovall, K.1    Sjovall, J.2
  • 114
    • 36549054059 scopus 로고    scopus 로고
    • Association of the multidrug-resistance-associated protein gene (ABCC2) variants with intrahepatic cholestasis of pregnancy
    • Sookoian S., Castano G., Burgueno A., Gianotti T.F., Pirola C.J. Association of the multidrug-resistance-associated protein gene (ABCC2) variants with intrahepatic cholestasis of pregnancy. J. Hepatol. 2008, 48:125-132.
    • (2008) J. Hepatol. , vol.48 , pp. 125-132
    • Sookoian, S.1    Castano, G.2    Burgueno, A.3    Gianotti, T.F.4    Pirola, C.J.5
  • 117
    • 79957629733 scopus 로고    scopus 로고
    • Pharmacogenetics of drug transporters in the enterohepatic circulation
    • Stieger B., Meier P.J. Pharmacogenetics of drug transporters in the enterohepatic circulation. Pharmacogenomics 2011, 12:611-631.
    • (2011) Pharmacogenomics , vol.12 , pp. 611-631
    • Stieger, B.1    Meier, P.J.2
  • 119
    • 0019522805 scopus 로고
    • Physiologic cholestasis: elevation of the primary serum bile acid concentrations in normal infants
    • Suchy F.J., Balistreri W.F., Heubi J.E., Searcy J.E., Levin R.S. Physiologic cholestasis: elevation of the primary serum bile acid concentrations in normal infants. Gastroenterology 1981, 80:1037-1041.
    • (1981) Gastroenterology , vol.80 , pp. 1037-1041
    • Suchy, F.J.1    Balistreri, W.F.2    Heubi, J.E.3    Searcy, J.E.4    Levin, R.S.5
  • 121
    • 33847064667 scopus 로고    scopus 로고
    • MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes
    • Trauner M., Fickert P., Wagner M. MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes. Semin. Liver Dis. 2007, 27:77-98.
    • (2007) Semin. Liver Dis. , vol.27 , pp. 77-98
    • Trauner, M.1    Fickert, P.2    Wagner, M.3
  • 122
    • 33646141823 scopus 로고    scopus 로고
    • Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy
    • Vallejo M., Briz O., Serrano M.A., Monte M.J., Marin J.J. Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy. J. Hepatol. 2006, 44:1150-1157.
    • (2006) J. Hepatol. , vol.44 , pp. 1150-1157
    • Vallejo, M.1    Briz, O.2    Serrano, M.A.3    Monte, M.J.4    Marin, J.J.5
  • 126
    • 0033026760 scopus 로고    scopus 로고
    • Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
    • Wang H., Chen J., Hollister K., Sowers L.C., Forman B.M. Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol. Cell 1999, 3:543-553.
    • (1999) Mol. Cell , vol.3 , pp. 543-553
    • Wang, H.1    Chen, J.2    Hollister, K.3    Sowers, L.C.4    Forman, B.M.5
  • 127
    • 33847005118 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy: the severe form is associated with common variants of the hepatobiliary phospholipid transporter ABCB4 gene
    • Wasmuth H.E., Glantz A., Keppeler H., Simon E., Bartz C., Rath W., Mattsson L.A., Marschall H.U., Lammert F. Intrahepatic cholestasis of pregnancy: the severe form is associated with common variants of the hepatobiliary phospholipid transporter ABCB4 gene. Gut 2007, 56:265-270.
    • (2007) Gut , vol.56 , pp. 265-270
    • Wasmuth, H.E.1    Glantz, A.2    Keppeler, H.3    Simon, E.4    Bartz, C.5    Rath, W.6    Mattsson, L.A.7    Marschall, H.U.8    Lammert, F.9
  • 129
    • 0035054627 scopus 로고    scopus 로고
    • The bile acid taurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis
    • Williamson C., Gorelik J., Eaton B.M., Lab M., de S.M., Korchev Y. The bile acid taurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis. Clin. Sci. (Lond.) 2001, 100:363-369.
    • (2001) Clin. Sci. (Lond.) , vol.100 , pp. 363-369
    • Williamson, C.1    Gorelik, J.2    Eaton, B.M.3    Lab, M.4    de, S.M.5    Korchev, Y.6
  • 132
    • 10344224570 scopus 로고    scopus 로고
    • The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity
    • Zhang J., Huang W., Qatanani M., Evans R.M., Moore D.D. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity. J. Biol. Chem. 2004, 279:49517-49522.
    • (2004) J. Biol. Chem. , vol.279 , pp. 49517-49522
    • Zhang, J.1    Huang, W.2    Qatanani, M.3    Evans, R.M.4    Moore, D.D.5


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