Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury

Pharmacogenetics and Genomics

Volumn 17, Issue 1, 2007, Pages 47-60

  Lang, Carmen ^a   Meier, Yvonne ^a   Stieger, Bruno ^a   Beuers, Ulrich ^b   Lang, Thomas ^c   Kerb, Reinhold ^c   Kullak Ublick, Gerd A ^a   Meier, Peter J ^a   Pauli Magnus, Christiane ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c Epidauros Biotechnologie AG   (Germany)

Author keywords

BSEP; Drug induced liver injury; Hepatocellular transporters; MDR3; Pharmacogenetics

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; ATORVASTATIN; AZITHROMYCIN; BILE SALT; CEFTRIAXONE; CELECOXIB; CYCLOSPORIN A; DIANE; ESOMEPRAZOLE; ETHINYLESTRADIOL PLUS LEVONORGESTREL; FLUCLOXACILLIN; FLUINDOSTATIN; MIANSERIN; MULTIDRUG RESISTANCE PROTEIN 3; NORFLOXACIN; PHENPROCOUMON; PIPERACILLIN PLUS TAZOBACTAM; RISPERIDONE; TAUROCHOLIC ACID; THIAMAZOLE; TRITIUM; VENLAFAXINE;

ABCB11 GENE; ABCB4 GENE; ADULT; AGED; ARTICLE; CAUCASIAN; CHOLESTASIS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; EXON; FEMALE; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC VARIABILITY; HUMAN; IN VITRO STUDY; LIVER CELL DAMAGE; LIVER INJURY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTASIS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LIVER DISEASES; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; P-GLYCOPROTEINS; POLYMORPHISM, GENETIC; PROTEIN STRUCTURE, SECONDARY; TAUROCHOLIC ACID;

EID: 33846589652     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/01.fpc.0000230418.28091.76     Document Type: Article

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