-
2
-
-
0034725724
-
Phagocytes and oxidative stress
-
Babior BM. Phagocytes and oxidative stress. Am J Med 2000;109:33-44.
-
(2000)
Am J Med
, vol.109
, pp. 33-44
-
-
Babior, B.M.1
-
3
-
-
0019365286
-
Altered oxidative metabolic responses in vitro of alveolar macrophages from asymptomatic cigarette smokers
-
Hoidal JR, Fox RB, LeMarbe PA, Perri R, Repine JE. Altered oxidative metabolic responses in vitro of alveolar macrophages from asymptomatic cigarette smokers. Am Rev Respir Dis 1981;123:85-89.
-
(1981)
Am Rev Respir Dis
, vol.123
, pp. 85-89
-
-
Hoidal, J.R.1
Fox, R.B.2
LeMarbe, P.A.3
Perri, R.4
Repine, J.E.5
-
4
-
-
0018611004
-
Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans
-
Gadek JE, Fells GA, Crystal RG. Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans. Science 1979;206:1315-1316.
-
(1979)
Science
, vol.206
, pp. 1315-1316
-
-
Gadek, J.E.1
Fells, G.A.2
Crystal, R.G.3
-
5
-
-
0023571643
-
Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of a1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase
-
Hubbard RC, Ogushi F, Fells GA, Cantin AM, Jallat S, Courtney M, Crystal RG. Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of a1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase. J Clin Invest 1987;80:1289-1295.
-
(1987)
J Clin Invest
, vol.80
, pp. 1289-1295
-
-
Hubbard, R.C.1
Ogushi, F.2
Fells, G.A.3
Cantin, A.M.4
Jallat, S.5
Courtney, M.6
Crystal, R.G.7
-
6
-
-
43449087654
-
Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice
-
Yao H, Edirisinghe I, Yang SR, Rajendrasozhan S, Kode A, Caito S, Adenuga D, Rahman I. Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice. Am J Pathol 2008;172:1222-1237.
-
(2008)
Am J Pathol
, vol.172
, pp. 1222-1237
-
-
Yao, H.1
Edirisinghe, I.2
Yang, S.R.3
Rajendrasozhan, S.4
Kode, A.5
Caito, S.6
Adenuga, D.7
Rahman, I.8
-
7
-
-
0019488694
-
Hydrogen peroxide kills Staphylococcus aureus by reacting with staphylococcal iron to form hydroxyl radical
-
Repine JE, Fox RB, Berger EM. Hydrogen peroxide kills Staphylococcus aureus by reacting with staphylococcal iron to form hydroxyl radical. J Biol Chem 1981;256:7094-7096.
-
(1981)
J Biol Chem
, vol.256
, pp. 7094-7096
-
-
Repine, J.E.1
Fox, R.B.2
Berger, E.M.3
-
8
-
-
0036400025
-
Ceruloplasmin metabolism and function
-
Hellman NE, Gitlin JD. Ceruloplasmin metabolism and function. Annu Rev Nutr 2002;22:439-458.
-
(2002)
Annu Rev Nutr
, vol.22
, pp. 439-458
-
-
Hellman, N.E.1
Gitlin, J.D.2
-
9
-
-
0027989345
-
Increased release of ferritin and iron by iron-loaded alveolar macrophages in cigarette smokers
-
Wesselius LJ, Nelson ME, Skikne BS. Increased release of ferritin and iron by iron-loaded alveolar macrophages in cigarette smokers. Am J Respir Crit Care Med 1994;150:690-695.
-
(1994)
Am J Respir Crit Care Med
, vol.150
, pp. 690-695
-
-
Wesselius, L.J.1
Nelson, M.E.2
Skikne, B.S.3
-
10
-
-
0026464982
-
Biological effects of cigarette smoke, wood smoke, and the smoke from plastics: The use of electron spin resonance
-
Pryor WA. Biological effects of cigarette smoke, wood smoke, and the smoke from plastics: the use of electron spin resonance. Free Radic Biol Med 1992;13:659-676.
-
(1992)
Free Radic Biol Med
, vol.13
, pp. 659-676
-
-
Pryor, W.A.1
-
11
-
-
0017097079
-
Electron spin resonance (ESR) study of cigarette smoke by use of spin trapping techniques
-
Pryor WA, Terauchi K, Davis WH Jr. Electron spin resonance (ESR) study of cigarette smoke by use of spin trapping techniques. Environ Health Perspect 1976;16:161-176.
-
(1976)
Environ Health Perspect
, vol.16
, pp. 161-176
-
-
Pryor, W.A.1
Terauchi, K.2
Davis, W.H.3
-
12
-
-
0001590580
-
Free radicals, ''reactive species'' and toxicology
-
In: Halliwell B, Gutteridge JMC, editors., 3rd ed. Oxford: Oxford University Press
-
Halliwell B, Gutteridge JMC. Free radicals, ''reactive species'' and toxicology. In: Halliwell B, Gutteridge JMC, editors. Free radicals in biology and medicine, 3rd ed. Oxford: Oxford University Press; 2000. pp. 544-616.
-
(2000)
Free Radicals in Biology and Medicine
, pp. 544-616
-
-
Halliwell, B.1
Gutteridge, J.M.C.2
-
13
-
-
0017755314
-
Possible mechanisms of emphysema in smokers: Cigarette smoke condensate suppresses protease inhibition in vitro
-
Janoff A, Carp H. Possible mechanisms of emphysema in smokers: cigarette smoke condensate suppresses protease inhibition in vitro. Am Rev Respir Dis 1977;116:65-72.
-
(1977)
Am Rev Respir Dis
, vol.116
, pp. 65-72
-
-
Janoff, A.1
Carp, H.2
-
14
-
-
0031428463
-
Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung
-
Asami S, Manabe H, Miyake J, Tsurudome Y, Hirano T, Yamaguchi R, Itoh H, Kasai H. Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung. Carcinogenesis 1997;18:1763-1766.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1763-1766
-
-
Asami, S.1
Manabe, H.2
Miyake, J.3
Tsurudome, Y.4
Hirano, T.5
Yamaguchi, R.6
Itoh, H.7
Kasai, H.8
-
15
-
-
18844434417
-
Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice
-
Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM. Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat Med 2005;11:491-498.
-
(2005)
Nat Med
, vol.11
, pp. 491-498
-
-
Petrache, I.1
Natarajan, V.2
Zhen, L.3
Medler, T.R.4
Richter, A.T.5
Cho, C.6
Hubbard, W.C.7
Berdyshev, E.V.8
Tuder, R.M.9
-
16
-
-
49049112707
-
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide
-
Petrache I, Medler TR, Richter AT, Kamocki K, Chukwueke U, Zhen L, Gu Y, Adamowicz J, Schweitzer KS, Hubbard WC, et al. Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. Am J Physiol Lung Cell Mol Physiol 2008;295:L44-L53.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
, pp. L44-L53
-
-
Petrache, I.1
Medler, T.R.2
Richter, A.T.3
Kamocki, K.4
Chukwueke, U.5
Zhen, L.6
Gu, Y.7
Adamowicz, J.8
Schweitzer, K.S.9
Hubbard, W.C.10
-
17
-
-
0029007943
-
Glutathione metabolism
-
Meister A. Glutathione metabolism. Methods Enzymol 1995;251:3-7.
-
(1995)
Methods Enzymol
, vol.251
, pp. 3-7
-
-
Meister, A.1
-
18
-
-
0029197657
-
Glutathione biosynthesis and its inhibition
-
Meister A. Glutathione biosynthesis and its inhibition. Methods Enzymol 1995;252:26-30.
-
(1995)
Methods Enzymol
, vol.252
, pp. 26-30
-
-
Meister, A.1
-
19
-
-
65049089113
-
Regulation of glutathione synthesis
-
Lu SC. Regulation of glutathione synthesis. Mol Aspects Med 2009;30: 42-59.
-
(2009)
Mol Aspects Med
, vol.30
, pp. 42-59
-
-
Lu, S.C.1
-
20
-
-
0030600535
-
Transcriptional regulation of g-glutamylcysteine synthetase-heavy subunit by oxidants in human alveolar epithelial cells
-
Rahman I, Bel A, Mulier B, Lawson MF, Harrison DJ, Macnee W, Smith CA. Transcriptional regulation of g-glutamylcysteine synthetase-heavy subunit by oxidants in human alveolar epithelial cells. Biochem Biophys Res Commun 1996;229:832-837.
-
(1996)
Biochem Biophys Res Commun
, vol.229
, pp. 832-837
-
-
Rahman, I.1
Bel, A.2
Mulier, B.3
Lawson, M.F.4
Harrison, D.J.5
Macnee, W.6
Smith, C.A.7
-
21
-
-
0030605012
-
Induction of g-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells
-
Rahman I, Smith CA, Lawson MF, Harrison DJ, MacNee W. Induction of g-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells. FEBS Lett 1996;396:21-25.
-
(1996)
FEBS Lett
, vol.396
, pp. 21-25
-
-
Rahman, I.1
Smith, C.A.2
Lawson, M.F.3
Harrison, D.J.4
MacNee, W.5
-
22
-
-
25144440916
-
Cloning and characterization of the human glutathione synthetase 59-flanking region
-
Lee TD, Yang H, Whang J, Lu SC. Cloning and characterization of the human glutathione synthetase 59-flanking region. Biochem J 2005; 390:521-528.
-
(2005)
Biochem J
, vol.390
, pp. 521-528
-
-
Lee, T.D.1
Yang, H.2
Whang, J.3
Lu, S.C.4
-
23
-
-
0033956744
-
The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin
-
Hayes JD, Chanas SA, Henderson CJ, McMahon M, Sun C, Moffat GJ, Wolf CR, Yamamoto M. The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin. Biochem Soc Trans 2000;28:33-41.
-
(2000)
Biochem Soc Trans
, vol.28
, pp. 33-41
-
-
Hayes, J.D.1
Chanas, S.A.2
Henderson, C.J.3
McMahon, M.4
Sun, C.5
Moffat, G.J.6
Wolf, C.R.7
Yamamoto, M.8
-
24
-
-
0142107445
-
Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate
-
Homolya L, Varadi A, Sarkadi B. Multidrug resistance-associated proteins: export pumps for conjugates with glutathione, glucuronate or sulfate. Biofactors 2003;17:103-114.
-
(2003)
Biofactors
, vol.17
, pp. 103-114
-
-
Homolya, L.1
Varadi, A.2
Sarkadi, B.3
-
25
-
-
36349015332
-
Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway
-
Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, Scheffer GL, Chan JY, Manautou JE, Chen Y, et al. Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology 2007;46:1597-1610.
-
(2007)
Hepatology
, vol.46
, pp. 1597-1610
-
-
Maher, J.M.1
Dieter, M.Z.2
Aleksunes, L.M.3
Slitt, A.L.4
Guo, G.5
Tanaka, Y.6
Scheffer, G.L.7
Chan, J.Y.8
Manautou, J.E.9
Chen, Y.10
-
26
-
-
0035885249
-
Oxidant-mediated lung epithelial cell tolerance: The role of intracellular glutathione and nuclear factor-kB
-
Rahman I, Mulier B, Gilmour PS, Watchorn T, Donaldson K, Jeffery PK, MacNee W. Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kB. Biochem Pharmacol 2001;62:787-794.
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 787-794
-
-
Rahman, I.1
Mulier, B.2
Gilmour, P.S.3
Watchorn, T.4
Donaldson, K.5
Jeffery, P.K.6
MacNee, W.7
-
27
-
-
0025457975
-
Extracellular glutathione suppresses human lung fibroblast proliferation
-
Cantin AM, Larivee P, Begin RO. Extracellular glutathione suppresses human lung fibroblast proliferation. Am J Respir Cell Mol Biol 1990; 3:79-85.
-
(1990)
Am J Respir Cell Mol Biol
, vol.3
, pp. 79-85
-
-
Cantin, A.M.1
Larivee, P.2
Begin, R.O.3
-
28
-
-
16844364420
-
Oxidative stress and airway inflammation in severe exacerbations of COPD
-
Drost EM, Skwarski KM, Sauleda J, Soler N, Roca J, Agusti A, MacNee W. Oxidative stress and airway inflammation in severe exacerbations of COPD. Thorax 2005;60:293-300.
-
(2005)
Thorax
, vol.60
, pp. 293-300
-
-
Drost, E.M.1
Skwarski, K.M.2
Sauleda, J.3
Soler, N.4
Roca, J.5
Agusti, A.6
MacNee, W.7
-
29
-
-
77954603744
-
Loss of cystic fibrosis transmembrane conductance regulator (CFTR) function enhances p38 and ERK MAPKs activation increasing IL-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa
-
Berube J, Roussel L, Nattagh L, Rousseau S. Loss of cystic fibrosis transmembrane conductance regulator (CFTR) function enhances p38 and ERK MAPKs activation increasing IL-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa. J Biol Chem 2010;285:22299-22307.
-
(2010)
J Biol Chem
, vol.285
, pp. 22299-22307
-
-
Berube, J.1
Roussel, L.2
Nattagh, L.3
Rousseau, S.4
-
30
-
-
0021842504
-
Transient depletion of lung glutathione by diethylmaleate enhances oxygen toxicity
-
Deneke SM, Lynch BA, Fanburg BL. Transient depletion of lung glutathione by diethylmaleate enhances oxygen toxicity. J Appl Physiol 1985;58:571-574.
-
(1985)
J Appl Physiol
, vol.58
, pp. 571-574
-
-
Deneke, S.M.1
Lynch, B.A.2
Fanburg, B.L.3
-
31
-
-
0034977190
-
TGF-b is a critical mediator of acute lung injury
-
Pittet JF, Griffiths MJ, Geiser T, Kaminski N, Dalton SL, Huang X, Brown LA, Gotwals PJ, Koteliansky VE, Matthay MA, et al. TGF-b is a critical mediator of acute lung injury. J Clin Invest 2001;107: 1537-1544.
-
(2001)
J Clin Invest
, vol.107
, pp. 1537-1544
-
-
Pittet, J.F.1
Griffiths, M.J.2
Geiser, T.3
Kaminski, N.4
Dalton, S.L.5
Huang, X.6
Brown, L.A.7
Gotwals, P.J.8
Koteliansky, V.E.9
Matthay, M.A.10
-
32
-
-
0033369168
-
Lung glutathione and oxidative stress: Implications in cigarette smoke-induced airway disease
-
Rahman I, MacNee W. Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease. Am J Physiol 1999;277:L1067-L1088.
-
(1999)
Am J Physiol
, vol.277
, pp. L1067-L1088
-
-
Rahman, I.1
MacNee, W.2
-
33
-
-
36348987864
-
Cigarette smoke irreversibly modifies glutathione in airway epithelial cells
-
van der Toorn M, Smit-de Vries MP, Slebos DJ, de Bruin HG, Abello N, van Oosterhout AJ, Bischoff R, Kauffman HF. Cigarette smoke irreversibly modifies glutathione in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 2007;293:L1156-L1162.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
, pp. L1156-L1162
-
-
Van Der Toorn, M.1
Smit-De Vries, M.P.2
Slebos, D.J.3
De Bruin, H.G.4
Abello, N.5
Van Oosterhout, A.J.6
Bischoff, R.7
Kauffman, H.F.8
-
34
-
-
0023263523
-
Normal alveolar epithelial lining fluid contains high levels of glutathione
-
Cantin AM, North SL, Hubbard RC, Crystal RG. Normal alveolar epithelial lining fluid contains high levels of glutathione. J Appl Physiol 1987;63:152-157.
-
(1987)
J Appl Physiol
, vol.63
, pp. 152-157
-
-
Cantin, A.M.1
North, S.L.2
Hubbard, R.C.3
Crystal, R.G.4
-
35
-
-
73949085683
-
Disparate oxidant gene expression of airway epithelium compared to alveolar macrophages in smokers
-
Carolan BJ, Harvey BG, Hackett NR, O'Connor TP, Cassano PA, Crystal RG. Disparate oxidant gene expression of airway epithelium compared to alveolar macrophages in smokers. Respir Res 2009;10: 111.
-
(2009)
Respir Res
, vol.10
, pp. 111
-
-
Carolan, B.J.1
Harvey, B.G.2
Hackett, N.R.3
O'Connor, T.P.4
Cassano, P.A.5
Crystal, R.G.6
-
36
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, YamamotoM, Petrache I, Tuder RM, Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 2004;114:1248-1259.
-
(2004)
J Clin Invest
, vol.114
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
Yamamoto, M.7
Petrache, I.8
Tuder, R.M.9
Biswal, S.10
-
37
-
-
14044254798
-
Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation
-
Kobayashi M, Yamamoto M. Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal 2005;7:385-394.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 385-394
-
-
Kobayashi, M.1
Yamamoto, M.2
-
38
-
-
53649099660
-
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema
-
Goven D, Boutten A, Lecon-Malas V, Marchal-Somme J, Amara N, Crestani B, Fournier M, Leseche G, Soler P, Boczkowski J, et al. Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema. Thorax 2008;63:916-924.
-
(2008)
Thorax
, vol.63
, pp. 916-924
-
-
Goven, D.1
Boutten, A.2
Lecon-Malas, V.3
Marchal-Somme, J.4
Amara, N.5
Crestani, B.6
Fournier, M.7
Leseche, G.8
Soler, P.9
Boczkowski, J.10
-
39
-
-
57349151482
-
Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease
-
Suzuki M, Betsuyaku T, Ito Y, Nagai K, Nasuhara Y, Kaga K, Kondo S, Nishimura M. Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2008;39:673-682.
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 673-682
-
-
Suzuki, M.1
Betsuyaku, T.2
Ito, Y.3
Nagai, K.4
Nasuhara, Y.5
Kaga, K.6
Kondo, S.7
Nishimura, M.8
-
40
-
-
51849129227
-
Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1
-
Malhotra D, Thimmulappa R, Navas-Acien A, Sandford A, Elliott M, Singh A, Chen L, Zhuang X, Hogg J, Pare P, et al. Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. Am J Respir Crit Care Med 2008;178:592-604.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 592-604
-
-
Malhotra, D.1
Thimmulappa, R.2
Navas-Acien, A.3
Sandford, A.4
Elliott, M.5
Singh, A.6
Chen, L.7
Zhuang, X.8
Hogg, J.9
Pare, P.10
-
41
-
-
77951642473
-
Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation
-
Blake DJ, Singh A, Kombairaju P, Malhotra D, Mariani TJ, Tuder RM, Gabrielson E, Biswal S. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. Am J Respir Cell Mol Biol 2010;42:524-536.
-
(2010)
Am J Respir Cell Mol Biol
, vol.42
, pp. 524-536
-
-
Blake, D.J.1
Singh, A.2
Kombairaju, P.3
Malhotra, D.4
Mariani, T.J.5
Tuder, R.M.6
Gabrielson, E.7
Biswal, S.8
-
42
-
-
20144383831
-
Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress
-
Dinkova-Kostova AT, Liby KT, Stephenson KK, Holtzclaw WD, Gao X, Suh N, Williams C, Risingsong R, Honda T, Gribble GW, et al. Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress. Proc Natl Acad Sci USA 2005;102:4584-4589.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4584-4589
-
-
Dinkova-Kostova, A.T.1
Liby, K.T.2
Stephenson, K.K.3
Holtzclaw, W.D.4
Gao, X.5
Suh, N.6
Williams, C.7
Risingsong, R.8
Honda, T.9
Gribble, G.W.10
-
43
-
-
62549160588
-
First-in-class, first-in-human phase i results of targeted agents: Highlights of the 2008 American Society of Clinical Oncology meeting
-
Molckovsky A, Siu LL. First-in-class, first-in-human phase i results of targeted agents: highlights of the 2008 American Society of Clinical Oncology meeting. J Hematol Oncol 2008;1:20.
-
(2008)
J Hematol Oncol
, vol.1
, pp. 20
-
-
Molckovsky, A.1
Siu, L.L.2
-
44
-
-
58549105575
-
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
-
Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, et al. Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proc Natl Acad Sci USA 2009;106:250-255.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 250-255
-
-
Sussan, T.E.1
Rangasamy, T.2
Blake, D.J.3
Malhotra, D.4
El-Haddad, H.5
Bedja, D.6
Yates, M.S.7
Kombairaju, P.8
Yamamoto, M.9
Liby, K.T.10
-
45
-
-
0037102347
-
4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease
-
Rahman I, van Schadewijk AA, Crowther AJ, Hiemstra PS, Stolk J, MacNee W, De Boer WI. 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002;166:490-495.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 490-495
-
-
Rahman, I.1
Van Schadewijk, A.A.2
Crowther, A.J.3
Hiemstra, P.S.4
Stolk, J.5
MacNee, W.6
De Boer, W.I.7
-
46
-
-
34447556991
-
Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease
-
Yoshida T, Tuder RM. Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiol Rev 2007;87:1047-1082.
-
(2007)
Physiol Rev
, vol.87
, pp. 1047-1082
-
-
Yoshida, T.1
Tuder, R.M.2
-
47
-
-
36249014327
-
Functional significance of apoptosis in chronic obstructive pulmonary disease
-
Park JW, Ryter SW, Choi AM. Functional significance of apoptosis in chronic obstructive pulmonary disease. COPD 2007;4:347-353.
-
(2007)
COPD
, vol.4
, pp. 347-353
-
-
Park, J.W.1
Ryter, S.W.2
Choi, A.M.3
-
48
-
-
33646561254
-
Immunohistochemical detection of apoptotic proteins, p53/Bax and JNK/FasL cascade, in the lung of rats exposed to cigarette smoke
-
Wu CH, Lin HH, Yan FP, Wang CJ. Immunohistochemical detection of apoptotic proteins, p53/Bax and JNK/FasL cascade, in the lung of rats exposed to cigarette smoke. Arch Toxicol 2006;80:328-336.
-
(2006)
Arch Toxicol
, vol.80
, pp. 328-336
-
-
Wu, C.H.1
Lin, H.H.2
Yan, F.P.3
Wang, C.J.4
-
49
-
-
0343484967
-
Tobacco smoke induces mitochondrial depolarization along with cell death: Effects of antioxidants
-
Banzet N, Francois D, Polla BS. Tobacco smoke induces mitochondrial depolarization along with cell death: effects of antioxidants. Redox Rep 1999;4:229-236.
-
(1999)
Redox Rep
, vol.4
, pp. 229-236
-
-
Banzet, N.1
Francois, D.2
Polla, B.S.3
-
50
-
-
0035077330
-
Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema
-
Kasahara Y, Tuder RM, Cool CD, Lynch DA, Flores SC, Voelkel NF. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med 2001;163:737-744.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 737-744
-
-
Kasahara, Y.1
Tuder, R.M.2
Cool, C.D.3
Lynch, D.A.4
Flores, S.C.5
Voelkel, N.F.6
-
51
-
-
0038465920
-
Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade
-
Tuder RM, Zhen L, Cho CY, Taraseviciene-Stewart L, Kasahara Y, Salvemini D, Voelkel NF, Flores SC. Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. Am J Respir Cell Mol Biol 2003;29:88-97.
-
(2003)
Am J Respir Cell Mol Biol
, vol.29
, pp. 88-97
-
-
Tuder, R.M.1
Zhen, L.2
Cho, C.Y.3
Taraseviciene-Stewart, L.4
Kasahara, Y.5
Salvemini, D.6
Voelkel, N.F.7
Flores, S.C.8
-
52
-
-
76149139431
-
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
-
Diab KJ, Adamowicz JJ, Kamocki K, Rush NI, Garrison J, Gu Y, Schweitzer KS, Skobeleva A, Rajashekhar G, Hubbard WC, et al. Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema. Am J Respir Crit Care Med 2010; 181:344-352.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 344-352
-
-
Diab, K.J.1
Adamowicz, J.J.2
Kamocki, K.3
Rush, N.I.4
Garrison, J.5
Gu, Y.6
Schweitzer, K.S.7
Skobeleva, A.8
Rajashekhar, G.9
Hubbard, W.C.10
-
53
-
-
66249127897
-
Cigarette smoke impairs clearance of apoptotic cells through oxidantdependent activation of rhoa
-
Richens TR, Linderman DJ, Horstmann SA, Lambert C, Xiao YQ, Keith RL, Boe DM, Morimoto K, Bowler RP, Day BJ, et al. Cigarette smoke impairs clearance of apoptotic cells through oxidantdependent activation of rhoa. Am J Respir Crit Care Med 2009;179: 1011-1021.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 1011-1021
-
-
Richens, T.R.1
Linderman, D.J.2
Horstmann, S.A.3
Lambert, C.4
Xiao, Y.Q.5
Keith, R.L.6
Boe, D.M.7
Morimoto, K.8
Bowler, R.P.9
Day, B.J.10
-
54
-
-
79955486468
-
Cigarette smoke-induced changes to alveolar macrophage phenotype and function is improved by treatment with procysteine
-
Jul 1. [Epub ahead of print
-
Hodge S, Matthews G, Mukaro V, Ahern J, Shivam A, Hodge G, Holmes M, Jersmann H, Reynolds PN. Cigarette smoke-induced changes to alveolar macrophage phenotype and function is improved by treatment with procysteine. Am J Respir Cell Mol Biol 2010. Jul 1. [Epub ahead of print].
-
(2010)
Am J Respir Cell Mol Biol
-
-
Hodge, S.1
Matthews, G.2
Mukaro, V.3
Ahern, J.4
Shivam, A.5
Hodge, G.6
Holmes, M.7
Jersmann, H.8
Reynolds, P.N.9
-
55
-
-
0036118562
-
Identification of a novel hypoxia-inducible factor 1-responsive gene RTP801 involved in apoptosis
-
Shoshani T, Faerman A, Mett I, Zelin E, Tenne T, Gorodin S, Moshel Y, Elbaz S, Budanov A, Chajut A, et al. Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. Mol Cell Biol 2002;22:2283-2293.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2283-2293
-
-
Shoshani, T.1
Faerman, A.2
Mett, I.3
Zelin, E.4
Tenne, T.5
Gorodin, S.6
Moshel, Y.7
Elbaz, S.8
Budanov, A.9
Chajut, A.10
-
56
-
-
0036863624
-
REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species
-
Ellisen LW, Ramsayer KD, Johannessen CM, Yang A, Beppu H, Minda K, Oliner JD, McKeon F, Haber DA. REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species. Mol Cell 2002;10:995-1005.
-
(2002)
Mol Cell
, vol.10
, pp. 995-1005
-
-
Ellisen, L.W.1
Ramsayer, K.D.2
Johannessen, C.M.3
Yang, A.4
Beppu, H.5
Minda, K.6
Oliner, J.D.7
McKeon, F.8
Haber, D.A.9
-
57
-
-
77954470662
-
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
-
Yoshida T, Mett I, Bhunia AK, Bowman J, Perez M, Zhang L, Gandjeva A, Zhen L, Chukwueke U, Mao T, et al. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nat Med 2010;16:767-773.
-
(2010)
Nat Med
, vol.16
, pp. 767-773
-
-
Yoshida, T.1
Mett, I.2
Bhunia, A.K.3
Bowman, J.4
Perez, M.5
Zhang, L.6
Gandjeva, A.7
Zhen, L.8
Chukwueke, U.9
Mao, T.10
-
58
-
-
0018579538
-
Cigarette smoke inhalation decreases a1-antitrypsin activity in rat lung
-
Janoff A, Carp H, Lee DK, Drew RT. Cigarette smoke inhalation decreases a1-antitrypsin activity in rat lung. Science 1979;206:1313-1314.
-
(1979)
Science
, vol.206
, pp. 1313-1314
-
-
Janoff, A.1
Carp, H.2
Lee, D.K.3
Drew, R.T.4
-
59
-
-
4444322565
-
Tumor necrosis factor-A drives 70% of cigarette smoke-induced emphysema in the mouse
-
Churg A,Wang RD, Tai H,Wang X, Xie C, Wright JL. Tumor necrosis factor-a drives 70% of cigarette smoke-induced emphysema in the mouse. Am J Respir Crit Care Med 2004;170:492-498.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 492-498
-
-
Churg, A.1
Wang, R.D.2
Tai, H.3
Wang, X.4
Xie, C.5
Wright, J.L.6
-
60
-
-
33846505023
-
IL-18 is induced and IL-18 receptor a plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation
-
Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, et al. IL-18 is induced and IL-18 receptor a plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation. J Immunol 2007;178:1948-1959.
-
(2007)
J Immunol
, vol.178
, pp. 1948-1959
-
-
Kang, M.J.1
Homer, R.J.2
Gallo, A.3
Lee, C.G.4
Crothers, K.A.5
Cho, S.J.6
Rochester, C.7
Cain, H.8
Chupp, G.9
Yoon, H.J.10
-
61
-
-
42049101172
-
Mechanisms of cigarette smoke-induced COPD: Insights from animal models
-
Churg A, Cosio M, Wright JL. Mechanisms of cigarette smoke-induced COPD: insights from animal models. Am J Physiol Lung Cell Mol Physiol 2008;294:L612-L631.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
, pp. L612-L631
-
-
Churg, A.1
Cosio, M.2
Wright, J.L.3
-
62
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997;277:2002-2004.
-
(1997)
Science
, vol.277
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, S.D.4
-
63
-
-
30344464994
-
A distinctive alveolar macrophage activation state induced by cigarette smoking
-
Woodruff PG, Koth LL, Yang YH, Rodriguez MW, Favoreto S, Dolganov GM, Paquet AC, Erle DJ. A distinctive alveolar macrophage activation state induced by cigarette smoking. Am J Respir Crit Care Med 2005;172:1383-1392.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 1383-1392
-
-
Woodruff, P.G.1
Koth, L.L.2
Yang, Y.H.3
Rodriguez, M.W.4
Favoreto, S.5
Dolganov, G.M.6
Paquet, A.C.7
Erle, D.J.8
-
64
-
-
74049134939
-
MMP12, lung function, and COPD in high-risk populations
-
Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melen E, Soderhall C, Hallberg J, et al. MMP12, lung function, and COPD in high-risk populations. N Engl J Med 2009;361:2599-2608.
-
(2009)
N Engl J Med
, vol.361
, pp. 2599-2608
-
-
Hunninghake, G.M.1
Cho, M.H.2
Tesfaigzi, Y.3
Soto-Quiros, M.E.4
Avila, L.5
Lasky-Su, J.6
Stidley, C.7
Melen, E.8
Soderhall, C.9
Hallberg, J.10
-
65
-
-
55549111247
-
Superoxide dismutase 3 polymorphism associated with reduced lung function in two large populations
-
Dahl M, Bowler RP, Juul K, Crapo JD, Levy S, Nordestgaard BG. Superoxide dismutase 3 polymorphism associated with reduced lung function in two large populations. Am J Respir Crit Care Med 2008; 178:906-912.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 906-912
-
-
Dahl, M.1
Bowler, R.P.2
Juul, K.3
Crapo, J.D.4
Levy, S.5
Nordestgaard, B.G.6
-
66
-
-
33749439171
-
Genetics of chronic obstructive pulmonary disease, beyond a1-antitrypsin deficiency
-
Sampsonas F, Karkoulias K, Kaparianos A, Spiropoulos K. Genetics of chronic obstructive pulmonary disease, beyond a1-antitrypsin deficiency. Curr Med Chem 2006;13:2857-2873.
-
(2006)
Curr Med Chem
, vol.13
, pp. 2857-2873
-
-
Sampsonas, F.1
Karkoulias, K.2
Kaparianos, A.3
Spiropoulos, K.4
-
67
-
-
43549093774
-
Structure and function of the polymeric mucins in airways mucus
-
Thornton DJ, Rousseau K, McGuckin MA. Structure and function of the polymeric mucins in airways mucus. Annu Rev Physiol 2008;70: 459-486.
-
(2008)
Annu Rev Physiol
, vol.70
, pp. 459-486
-
-
Thornton, D.J.1
Rousseau, K.2
McGuckin, M.A.3
-
68
-
-
3242706027
-
Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-A converting enzyme in human airway epithelial (NCI-H292) cells
-
Shao MX, Nakanaga T, Nadel JA. Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-a converting enzyme in human airway epithelial (NCI-H292) cells. Am J Physiol Lung Cell Mol Physiol 2004;287:L420-L427.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
, pp. L420-L427
-
-
Shao, M.X.1
Nakanaga, T.2
Nadel, J.A.3
-
69
-
-
0034141938
-
Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: Role of neutrophils
-
Takeyama K, Dabbagh K, Jeong Shim J, Dao-Pick T, Ueki IF, Nadel JA. Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. J Immunol 2000;164:1546-1552.
-
(2000)
J Immunol
, vol.164
, pp. 1546-1552
-
-
Takeyama, K.1
Dabbagh, K.2
Jeong Shim, J.3
Dao-Pick, T.4
Ueki, I.F.5
Nadel, J.A.6
-
70
-
-
17144457047
-
Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation
-
Saetta M, Turato G, Baraldo S, Zanin A, Braccioni F, Mapp CE, Maestrelli P, Cavallesco G, Papi A, Fabbri LM. Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation. Am J Respir Crit Care Med 2000;161:1016-1021.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 1016-1021
-
-
Saetta, M.1
Turato, G.2
Baraldo, S.3
Zanin, A.4
Braccioni, F.5
Mapp, C.E.6
Maestrelli, P.7
Cavallesco, G.8
Papi, A.9
Fabbri, L.M.10
-
71
-
-
33947492517
-
Regulation of MUC5AC expression by NAD(P)H:quinone oxidoreductase 1
-
Zheng S, Byrd AS, Fischer BM, Grover AR, Ghio AJ, Voynow JA. Regulation of MUC5AC expression by NAD(P)H:quinone oxidoreductase 1. Free Radic Biol Med 2007;42:1398-1408.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 1398-1408
-
-
Zheng, S.1
Byrd, A.S.2
Fischer, B.M.3
Grover, A.R.4
Ghio, A.J.5
Voynow, J.A.6
-
72
-
-
7444252099
-
Potential for antioxidant therapy of cystic fibrosis
-
Cantin AM. Potential for antioxidant therapy of cystic fibrosis. Curr Opin Pulm Med 2004;10:531-536.
-
(2004)
Curr Opin Pulm Med
, vol.10
, pp. 531-536
-
-
Cantin, A.M.1
-
73
-
-
0034190297
-
Protein kinase C signaling and oxidative stress
-
Gopalakrishna R, Jaken S. Protein kinase C signaling and oxidative stress. Free Radic Biol Med 2000;28:1349-1361.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 1349-1361
-
-
Gopalakrishna, R.1
Jaken, S.2
-
74
-
-
0035798685
-
MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro
-
Li Y, Martin LD, Spizz G, Adler KB. MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro. J Biol Chem 2001;276:40982-40990.
-
(2001)
J Biol Chem
, vol.276
, pp. 40982-40990
-
-
Li, Y.1
Martin, L.D.2
Spizz, G.3
Adler, K.B.4
-
75
-
-
1242271091
-
A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma
-
Singer M, Martin LD, Vargaftig BB, Park J, Gruber AD, Li Y, Adler KB. A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma. Nat Med 2004;10:193-196.
-
(2004)
Nat Med
, vol.10
, pp. 193-196
-
-
Singer, M.1
Martin, L.D.2
Vargaftig, B.B.3
Park, J.4
Gruber, A.D.5
Li, Y.6
Adler, K.B.7
-
76
-
-
0023186626
-
Interaction between oxygen radicals and gastric mucin
-
Grisham MB, Von Ritter C, Smith BF, Lamont JT, Granger DN. Interaction between oxygen radicals and gastric mucin. Am J Physiol 1987;253:G93-G96.
-
(1987)
Am J Physiol
, vol.253
, pp. G93-G96
-
-
Grisham, M.B.1
Von Ritter, C.2
Smith, B.F.3
Lamont, J.T.4
Granger, D.N.5
-
77
-
-
0021272862
-
Antioxidant protection: A function of tracheobronchial and gastrointestinal mucus
-
Cross CE, Halliwell B, Allen A. Antioxidant protection: a function of tracheobronchial and gastrointestinal mucus. Lancet 1984;1:1328-1330.
-
(1984)
Lancet
, vol.1
, pp. 1328-1330
-
-
Cross, C.E.1
Halliwell, B.2
Allen, A.3
-
78
-
-
0028558599
-
Oxidants, antioxidants, and respiratory tract lining fluids
-
Cross CE, van der Vliet A, O'Neill CA, Louie S, Halliwell B. Oxidants, antioxidants, and respiratory tract lining fluids. Environ Health Perspect 1994;102:185-191.
-
(1994)
Environ Health Perspect
, vol.102
, pp. 185-191
-
-
Cross, C.E.1
Van Der Vliet, A.2
O'Neill, C.A.3
Louie, S.4
Halliwell, B.5
-
79
-
-
0033773964
-
Albumin-mediated regulation of cellular glutathione and nuclear factor kB activation
-
Cantin AM, Paquette B, Richter M, Larivee P. Albumin-mediated regulation of cellular glutathione and nuclear factor kB activation. Am J Respir Crit Care Med 2000;162:1539-1546.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1539-1546
-
-
Cantin, A.M.1
Paquette, B.2
Richter, M.3
Larivee, P.4
-
80
-
-
33744748625
-
Regulation of mucin genes in chronic inflammatory airway diseases
-
Voynow JA, Gendler SJ, Rose MC. Regulation of mucin genes in chronic inflammatory airway diseases. Am J Respir Cell Mol Biol 2006;34:661-665.
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, pp. 661-665
-
-
Voynow, J.A.1
Gendler, S.J.2
Rose, M.C.3
-
81
-
-
70349223856
-
Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion
-
Garcia MA, Yang N, Quinton PM. Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion. J Clin Invest 2009;119:2613-2622.
-
(2009)
J Clin Invest
, vol.119
, pp. 2613-2622
-
-
Garcia, M.A.1
Yang, N.2
Quinton, P.M.3
-
82
-
-
0035988475
-
Acidic pH and increasing [Ca21] reduce the swelling of mucins in primary cultures of human cervical cells
-
Espinosa M, Noe G, Troncoso C, Ho SB, Villalon M. Acidic pH and increasing [Ca21] reduce the swelling of mucins in primary cultures of human cervical cells. Hum Reprod 2002;17:1964-1972.
-
(2002)
Hum Reprod
, vol.17
, pp. 1964-1972
-
-
Espinosa, M.1
Noe, G.2
Troncoso, C.3
Ho, S.B.4
Villalon, M.5
-
83
-
-
7044270542
-
From mucins to mucus: Toward a more coherent understanding of this essential barrier
-
Thornton DJ, Sheehan JK. From mucins to mucus: toward a more coherent understanding of this essential barrier. Proc Am Thorac Soc 2004;1:54-61.
-
(2004)
Proc Am Thorac Soc
, vol.1
, pp. 54-61
-
-
Thornton, D.J.1
Sheehan, J.K.2
-
85
-
-
0037027912
-
An overview of the pathogenesis of cystic fibrosis lung disease
-
Boucher RC. An overview of the pathogenesis of cystic fibrosis lung disease. Adv Drug Deliv Rev 2002;54:1359-1371.
-
(2002)
Adv Drug Deliv Rev
, vol.54
, pp. 1359-1371
-
-
Boucher, R.C.1
-
86
-
-
0037101920
-
Oxidant stress stimulates anion secretion from the human airway epithelial cell line Calu-3: Implications for cystic fibrosis lung disease
-
Cowley EA, Linsdell P. Oxidant stress stimulates anion secretion from the human airway epithelial cell line Calu-3: Implications for cystic fibrosis lung disease. J Physiol 2002;543:201-209.
-
(2002)
J Physiol
, vol.543
, pp. 201-209
-
-
Cowley, E.A.1
Linsdell, P.2
-
87
-
-
7144257864
-
Effect of t-butylhydroperoxide on chloride secretion in rat tracheal epithelia
-
Jung JS, Lee JY, Oh SO, Jang PG, Bae HR, Kim YK, Lee SH. Effect of t-butylhydroperoxide on chloride secretion in rat tracheal epithelia. Pharmacol Toxicol 1998;82:236-242.
-
(1998)
Pharmacol Toxicol
, vol.82
, pp. 236-242
-
-
Jung, J.S.1
Lee, J.Y.2
Oh, S.O.3
Jang, P.G.4
Bae, H.R.5
Kim, Y.K.6
Lee, S.H.7
-
88
-
-
0028123278
-
Modulation of human colonic T84 cell secretion by hydrogen peroxide
-
Nguyen TD, Canada AT. Modulation of human colonic T84 cell secretion by hydrogen peroxide. Biochem Pharmacol 1994;47:403-410.
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 403-410
-
-
Nguyen, T.D.1
Canada, A.T.2
-
89
-
-
0025785755
-
Monochloramine, a neutrophil-derived oxidant, stimulates rat colonic secretion
-
Tamai H, Kachur JF, Baron DA, Grisham MB, Gaginella TS. Monochloramine, a neutrophil-derived oxidant, stimulates rat colonic secretion. J Pharmacol Exp Ther 1991;257:887-894.
-
(1991)
J Pharmacol Exp Ther
, vol.257
, pp. 887-894
-
-
Tamai, H.1
Kachur, J.F.2
Baron, D.A.3
Grisham, M.B.4
Gaginella, T.S.5
-
90
-
-
33644833034
-
Oxidant stress suppresses CFTR expression
-
Cantin AM, Bilodeau G, Ouellet C, Liao J, Hanrahan JW. Oxidant stress suppresses CFTR expression. Am J Physiol Cell Physiol 2006; 290:C262-C270.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
, pp. C262-C270
-
-
Cantin, A.M.1
Bilodeau, G.2
Ouellet, C.3
Liao, J.4
Hanrahan, J.W.5
-
91
-
-
33646540731
-
Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers
-
Cantin AM, Hanrahan JW, Bilodeau G, Ellis L, Dupuis A, Liao J, Zielenski J, Durie P. Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers. Am J Respir Crit Care Med 2006;173:1139-1144.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 1139-1144
-
-
Cantin, A.M.1
Hanrahan, J.W.2
Bilodeau, G.3
Ellis, L.4
Dupuis, A.5
Liao, J.6
Zielenski, J.7
Durie, P.8
-
92
-
-
77954382291
-
Cadmium regulates the expression of the CFTR chloride channel in human airway epithelial cells
-
Rennolds J, Butler S, Maloney K, Boyaka PN, Davis IC, Knoell DL, Parinandi NL, Cormet-Boyaka E. Cadmium regulates the expression of the CFTR chloride channel in human airway epithelial cells. Toxicol Sci 2010;116:349-358.
-
(2010)
Toxicol Sci
, vol.116
, pp. 349-358
-
-
Rennolds, J.1
Butler, S.2
Maloney, K.3
Boyaka, P.N.4
Davis, I.C.5
Knoell, D.L.6
Parinandi, N.L.7
Cormet-Boyaka, E.8
-
93
-
-
45549093249
-
The mechanism of cystic fibrosis transmembrane conductance regulator transcriptional repression during the unfolded protein response
-
Bartoszewski R, Rab A, Twitty G, Stevenson L, Fortenberry J, Piotrowski A, Dumanski JP, Bebok Z. The mechanism of cystic fibrosis transmembrane conductance regulator transcriptional repression during the unfolded protein response. J Biol Chem 2008;283:12154-12165.
-
(2008)
J Biol Chem
, vol.283
, pp. 12154-12165
-
-
Bartoszewski, R.1
Rab, A.2
Twitty, G.3
Stevenson, L.4
Fortenberry, J.5
Piotrowski, A.6
Dumanski, J.P.7
Bebok, Z.8
-
94
-
-
0036198469
-
Cysteine residues in the nucleotide binding domains regulate the conductance state of CFTR channels
-
Harrington MA, Kopito RR. Cysteine residues in the nucleotide binding domains regulate the conductance state of CFTR channels. Biophys J 2002;82:1278-1292.
-
(2002)
Biophys J
, vol.82
, pp. 1278-1292
-
-
Harrington, M.A.1
Kopito, R.R.2
-
95
-
-
0031954680
-
Uncertainty in the diagnosis of cystic fibrosis: Possible role of in vivo nasal potential difference measurements
-
Wilson DC, Ellis L, Zielenski J, Corey M, Ip WF, Tsui LC, Tullis E, Knowles MR, Durie PR. Uncertainty in the diagnosis of cystic fibrosis: possible role of in vivo nasal potential difference measurements. J Pediatr 1998;132:596-599.
-
(1998)
J Pediatr
, vol.132
, pp. 596-599
-
-
Wilson, D.C.1
Ellis, L.2
Zielenski, J.3
Corey, M.4
Ip, W.F.5
Tsui, L.C.6
Tullis, E.7
Knowles, M.R.8
Durie, P.R.9
-
96
-
-
33645130994
-
Cystic fibrosis since 1938
-
Davis PB. Cystic fibrosis since 1938. Am J Respir Crit Care Med 2006; 173:475-482.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 475-482
-
-
Davis, P.B.1
-
97
-
-
0032433707
-
Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
-
Matsui H, Grubb BR, Tarran R, Randell SH, Gatzy JT, Davis CW, Boucher RC. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell 1998;95:1005-1015.
-
(1998)
Cell
, vol.95
, pp. 1005-1015
-
-
Matsui, H.1
Grubb, B.R.2
Tarran, R.3
Randell, S.H.4
Gatzy, J.T.5
Davis, C.W.6
Boucher, R.C.7
-
98
-
-
42949118737
-
Cigarette smoke induces an unfolded protein response in the human lung: A proteomic approach
-
Kelsen SG, Duan X, Ji R, Perez O, Liu C, Merali S. Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach. Am J Respir Cell Mol Biol 2008;38:541-550.
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 541-550
-
-
Kelsen, S.G.1
Duan, X.2
Ji, R.3
Perez, O.4
Liu, C.5
Merali, S.6
-
99
-
-
22244446505
-
The mammalian unfolded protein response
-
Schroder M, Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem 2005;74:739-789.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
100
-
-
23644436847
-
Endoplasmic reticulum quality control and apoptosis
-
Groenendyk J, Michalak M. Endoplasmic reticulum quality control and apoptosis. Acta Biochim Pol 2005;52:381-395.
-
(2005)
Acta Biochim Pol
, vol.52
, pp. 381-395
-
-
Groenendyk, J.1
Michalak, M.2
-
101
-
-
0033634641
-
Perk is essential for translational regulation and cell survival during the unfolded protein response
-
Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 2000;5:897-904.
-
(2000)
Mol Cell
, vol.5
, pp. 897-904
-
-
Harding, H.P.1
Zhang, Y.2
Bertolotti, A.3
Zeng, H.4
Ron, D.5
-
102
-
-
29244462498
-
Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway
-
Cullinan SB, Diehl JA. Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway. Int J Biochem Cell Biol 2006;38:317-332.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 317-332
-
-
Cullinan, S.B.1
Diehl, J.A.2
|