메뉴 건너뛰기




Volumn 17, Issue 3, 2013, Pages 119-129

Omics of HER2-positive breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 7; LAPATINIB; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; TRASTUZUMAB;

EID: 84875137889     PISSN: 15362310     EISSN: 15578100     Source Type: Journal    
DOI: 10.1089/omi.2012.0099     Document Type: Review
Times cited : (26)

References (84)
  • 1
    • 40949086031 scopus 로고    scopus 로고
    • GRB-7 facilitates HER-2/Neu-mediated signal transduction and tumor formation
    • Bai T, and Luoh SW. (2008). GRB-7 facilitates HER-2/Neu-mediated signal transduction and tumor formation. Carcinogenesis 29, 473-479.
    • (2008) Carcinogenesis , vol.29 , pp. 473-479
    • Bai, T.1    Luoh, S.W.2
  • 2
    • 84877302244 scopus 로고    scopus 로고
    • Trastuzumab-DM1: A clinical update of the novel antibody-drug conjugate for HER2-overexpressing breast cancer
    • doi:10.2119/molmed.2012.00302
    • Barginear MF, John V, and Budman DR. (2012). Trastuzumab-DM1: A clinical update of the novel antibody-drug conjugate for HER2-overexpressing breast cancer. Mol Med doi:10.2119/molmed.2012.00302.
    • (2012) Mol Med
    • Barginear, M.F.1    John, V.2    Budman, D.R.3
  • 3
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer mechanism for early oncogenic pathway addiction?
    • Baylin SB, and Ohm JE. (2006). Epigenetic gene silencing in cancer mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6,107-116.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 4
    • 78650877915 scopus 로고    scopus 로고
    • DNA methylation epigenotypes in breast cancer molecular subtypes
    • Bediaga NG, Acha-Sagredo A, Guerra I, et al. (2010). DNA methylation epigenotypes in breast cancer molecular subtypes. Breast Cancer Res 12, R77.
    • (2010) Breast Cancer Res , vol.12
    • Bediaga, N.G.1    Acha-Sagredo, A.2    Guerra, I.3
  • 5
    • 22844440427 scopus 로고    scopus 로고
    • Identification of hundreds of conserved and nonconserved human micro-RNAs
    • Bentwich I, Avniel A, Karov Y, et al. (2005). Identification of hundreds of conserved and nonconserved human micro-RNAs. Nat Genet 37, 766-770.
    • (2005) Nat Genet , vol.37 , pp. 766-770
    • Bentwich, I.1    Avniel, A.2    Karov, Y.3
  • 6
    • 33846563430 scopus 로고    scopus 로고
    • Elucidation of a protein signature discriminating six common types of adenocarcinoma
    • Bloom GC, Eschrich S, Zhou JX, Coppola D, and Yeatman T. (2007). Elucidation of a protein signature discriminating six common types of adenocarcinoma. Int J Cancer 120, 769-775.
    • (2007) Int J Cancer , vol.120 , pp. 769-775
    • Bloom, G.C.1    Eschrich, S.2    Zhou, J.X.3    Coppola, D.4    Yeatman, T.5
  • 7
    • 70949095656 scopus 로고    scopus 로고
    • Involvement of the HER2 pathway in repair of DNA damage produced by chemotherapeutic agents
    • Boone JJ, Bhosle J, Tilby MJ, Hartley JA, and Hochhauser D. (2009). Involvement of the HER2 pathway in repair of DNA damage produced by chemotherapeutic agents. Mol. Cancer Ther 9, 3015-3023.
    • (2009) Mol. Cancer Ther , vol.9 , pp. 3015-3023
    • Boone, J.J.1    Bhosle, J.2    Tilby, M.J.3    Hartley, J.A.4    Hochhauser, D.5
  • 8
    • 57749120767 scopus 로고    scopus 로고
    • Proteomic analysis of breast cancer molecular subtypes and biomarkers of response to targeted kinase inhibitors using reverse-phase protein microarrays
    • Boyd ZS, Wu QJ, O'Brien C, et al. (2008). Proteomic analysis of breast cancer molecular subtypes and biomarkers of response to targeted kinase inhibitors using reverse-phase protein microarrays. Mol Cancer Ther 7, 3695-3706.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3695-3706
    • Boyd, Z.S.1    Wu, Q.J.2    O'Brien, C.3
  • 9
    • 39649089387 scopus 로고    scopus 로고
    • Contribution of proteomics to the study of the role of cytokeratins in disease and physiopathology
    • Brouillard F, Fritsch J, Edelman A, and Ollero M. (2008). Contribution of proteomics to the study of the role of cytokeratins in disease and physiopathology. Proteomics Clin Appl 2, 264-285.
    • (2008) Proteomics Clin Appl , vol.2 , pp. 264-285
    • Brouillard, F.1    Fritsch, J.2    Edelman, A.3    Ollero, M.4
  • 10
    • 84868100929 scopus 로고    scopus 로고
    • MicroRNA-200 family modulation in distinct breast cancer phenotypes
    • Castilla MÁ, Díaz-Martín J, Sarrió D, et al. (2012). MicroRNA-200 family modulation in distinct breast cancer phenotypes. PLoS One 7: e47709.
    • (2012) PLoS One , vol.7
    • Má, C.1    Díaz-Martín, J.2    Sarrió, D.3
  • 11
    • 33750285970 scopus 로고    scopus 로고
    • Identification of alpha-enolase as an autoantigen in lung cancer: Its overexpression is associated with clinical outcomes
    • Chang GC, Liu KJ, Hsieh CL, et al. (2006). Identification of alpha-enolase as an autoantigen in lung cancer: Its overexpression is associated with clinical outcomes. Clin Cancer Res 12, 5746-5754.
    • (2006) Clin Cancer Res , vol.12 , pp. 5746-5754
    • Chang, G.C.1    Liu, K.J.2    Hsieh, C.L.3
  • 13
    • 84859771372 scopus 로고    scopus 로고
    • Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer
    • Cheng Q, Chang JT, Geradts J, et al. (2012). Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer. Breast Cancer Res 14, R62.
    • (2012) Breast Cancer Res , vol.14
    • Cheng, Q.1    Chang, J.T.2    Geradts, J.3
  • 14
    • 33845191779 scopus 로고    scopus 로고
    • Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
    • Chin K, DeVries S, Fridlyand J, et al. (2006). Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 10, 529-541.
    • (2006) Cancer Cell , vol.10 , pp. 529-541
    • Chin, K.1    Devries, S.2    Fridlyand, J.3
  • 15
    • 57749089646 scopus 로고    scopus 로고
    • Genomewide allelic state analysis on flow-sorted tumor fractions provides an accurate measure of chromosomal aberrations
    • Corver WE, Middeldorp A, ter Haar NT, et al. (2008). Genomewide allelic state analysis on flow-sorted tumor fractions provides an accurate measure of chromosomal aberrations. Cancer Res 68, 10333-10340.
    • (2008) Cancer Res , vol.68 , pp. 10333-10340
    • Corver, W.E.1    Middeldorp, A.2    Ter Haar, N.T.3
  • 16
    • 34247890015 scopus 로고    scopus 로고
    • Assessing serum cytokine profiles in breast cancer patients receiving a HER2/neu vaccine using Luminex technology
    • Dehqanzada ZA, Storrer CE, Hueman MT, et al. (2007). Assessing serum cytokine profiles in breast cancer patients receiving a HER2/neu vaccine using Luminex technology. Oncol Rep 17, 687-694.
    • (2007) Oncol Rep , vol.17 , pp. 687-694
    • Dehqanzada, Z.A.1    Storrer, C.E.2    Hueman, M.T.3
  • 17
    • 80054061796 scopus 로고    scopus 로고
    • Hormone receptor and ERBB2 status in gene expression profiles of human breast tumor samples
    • Dvorkin-Gheva A, and Hassell JA. (2011). Hormone receptor and ERBB2 status in gene expression profiles of human breast tumor samples. PLoS One 6, e26023.
    • (2011) PLoS One , vol.6
    • Dvorkin-Gheva, A.1    Hassell, J.A.2
  • 18
    • 56449111358 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase hyperactivation results in lapatinib resistance that is reversed by the mTOR/phosphatidylinositol 3-kinase inhibitor NVP-BEZ235
    • Eichhorn PJ, Gili M, Scaltriti M, et al. (2008). Phosphatidylinositol 3-kinase hyperactivation results in lapatinib resistance that is reversed by the mTOR/phosphatidylinositol 3-kinase inhibitor NVP-BEZ235. Cancer Res 68, 9221-9230.
    • (2008) Cancer Res , vol.68 , pp. 9221-9230
    • Eichhorn, P.J.1    Gili, M.2    Scaltriti, M.3
  • 19
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs-microRNAs with a role in cancer
    • Esquela-Kerscher A, and Slack FJ. (2006). Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 6, 259-269.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 20
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone modification maps
    • Esteller M. (2007). Cancer epigenomics: DNA methylomes and histone modification maps. Nat Rev Genet 8, 286-298.
    • (2007) Nat Rev Genet , vol.8 , pp. 286-298
    • Esteller, M.1
  • 21
    • 77957352037 scopus 로고    scopus 로고
    • PTEN, PIK3CA, p-AKT, and p-p70S6K status: Association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer
    • Esteva FJ, Guo H, Zhang S, et al. (2010). PTEN, PIK3CA, p-AKT, and p-p70S6K status: Association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer. Am J Pathol 177, 1647-1656.
    • (2010) Am J Pathol , vol.177 , pp. 1647-1656
    • Esteva, F.J.1    Guo, H.2    Zhang, S.3
  • 22
    • 11144348206 scopus 로고    scopus 로고
    • Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells
    • Faltus T, Yuan J, Zimmer B, et al. (2004). Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu- overexpressing breast cancer cells. Neoplasia 6, 786-795.
    • (2004) Neoplasia , vol.6 , pp. 786-795
    • Faltus, T.1    Yuan, J.2    Zimmer, B.3
  • 23
    • 31544435739 scopus 로고    scopus 로고
    • Breast cancer DNA methylation profiles in cancer cells and tumor stroma: Association with HER-2/neu status in primary breast cancer
    • Fiegl H, Millinger S, Goebel G, et al. (2006). Breast cancer DNA methylation profiles in cancer cells and tumor stroma: Association with HER-2/neu status in primary breast cancer. Cancer Res 66, 29-33.
    • (2006) Cancer Res , vol.66 , pp. 29-33
    • Fiegl, H.1    Millinger, S.2    Goebel, G.3
  • 24
    • 84855568731 scopus 로고    scopus 로고
    • HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicin-based dose-dense sequential chemotherapy
    • Fountzilas G, Valavanis C, Kotoula V, et al. (2012). HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicin-based dose-dense sequential chemotherapy. J Transl Med 10, 10.
    • (2012) J Transl Med , vol.10 , pp. 10
    • Fountzilas, G.1    Valavanis, C.2    Kotoula, V.3
  • 25
    • 27744484362 scopus 로고    scopus 로고
    • Mammary carcinoma provides highly tumorigenic and invasive reactive stromal cells
    • Galiè M, Sorrentino C, Montani M, et al. (2005). Mammary carcinoma provides highly tumorigenic and invasive reactive stromal cells. Carcinogenesis 26, 1868-1878.
    • (2005) Carcinogenesis , vol.26 , pp. 1868-1878
    • Galiè, M.1    Sorrentino, C.2    Montani, M.3
  • 26
    • 0242584449 scopus 로고    scopus 로고
    • Induction of tumors in mice by genomic hypomethylation
    • Gaudet F, Hodgson JG, Eden A, et al. (2003). Induction of tumors in mice by genomic hypomethylation. Science 300, 489-492.
    • (2003) Science , vol.300 , pp. 489-492
    • Gaudet, F.1    Hodgson, J.G.2    Eden, A.3
  • 27
    • 84872347005 scopus 로고    scopus 로고
    • Utilization of HER2 genetic testing in a multiinstitutional observational study
    • Goddard KA, Aiello Bowles EJ, Spencer Feigelson H, et al. (2012). Utilization of HER2 genetic testing in a multiinstitutional observational study. Am J Manag Care 18, 704-712.
    • (2012) Am J Manag Care , vol.18 , pp. 704-712
    • Goddard, K.A.1    Aiello Bowles, E.J.2    Spencer Feigelson, H.3
  • 28
    • 78650486082 scopus 로고    scopus 로고
    • Clinical application of proteomics in breast cancer: State of the art and perspectives
    • Goncalves A, and Bertucci F. (2011). Clinical application of proteomics in breast cancer: State of the art and perspectives. Med Princ Pract 20, 4-18.
    • (2011) Med Princ Pract , vol.20 , pp. 4-18
    • Goncalves, A.1    Bertucci, F.2
  • 29
    • 42549116694 scopus 로고    scopus 로고
    • Current issues in ER and HER2 testing by IHC in breast cancer
    • Gown AM. (2008). Current issues in ER and HER2 testing by IHC in breast cancer. Mod Pathol 21, S8-15.
    • (2008) Mod Pathol , vol.21
    • Gown, A.M.1
  • 30
    • 79956372637 scopus 로고    scopus 로고
    • Molecular pathology of breast cancer: The journey from traditional practice toward embracing the complexity of a molecular classification
    • Gruver AM. (2011). Molecular pathology of breast cancer: The journey from traditional practice toward embracing the complexity of a molecular classification. Arch Pathol Lab Med 135, 546-557.
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 546-557
    • Gruver, A.M.1
  • 31
    • 44449130082 scopus 로고    scopus 로고
    • Identification of tumor antigens that elicit a humoral immune response in breast cancer patients' sera by serological proteome analysis (SERPA
    • Hamrita B, Chahed K, Kabbage M, et al. (2008). Identification of tumor antigens that elicit a humoral immune response in breast cancer patients' sera by serological proteome analysis (SERPA). Clin Chim Acta 393, 95-102.
    • (2008) Clin Chim Acta , vol.393 , pp. 95-102
    • Hamrita, B.1    Chahed, K.2    Kabbage, M.3
  • 32
    • 77958540564 scopus 로고    scopus 로고
    • Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
    • Holm K, Hegardt C, Staaf J, et al. (2010). Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns. Breast Cancer Res 12, R36.
    • (2010) Breast Cancer Res , vol.12
    • Holm, K.1    Hegardt, C.2    Staaf, J.3
  • 33
    • 65549165975 scopus 로고    scopus 로고
    • Genetic alterations and oncogenic pathways associated with breast cancer subtypes
    • Hu X, Stern HM, Ge L, et al. (2009). Genetic alterations and oncogenic pathways associated with breast cancer subtypes. Mol Cancer Res 7, 511-522.
    • (2009) Mol Cancer Res , vol.7 , pp. 511-522
    • Hu, X.1    Stern, H.M.2    Ge, L.3
  • 34
    • 33646874546 scopus 로고    scopus 로고
    • The molecular portraits of breast tumors are conserved across microarray platforms
    • Hu Z, Fan C, Oh DS, et al. (2006). The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genom 7, 96.
    • (2006) BMC Genom , vol.7 , pp. 96
    • Hu, Z.1    Fan, C.2    Oh, D.S.3
  • 35
    • 78650967232 scopus 로고    scopus 로고
    • Phase i trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pretreated patients with HER2-overexpressing metastatic breast cancer
    • Jerusalem G, Fasolo A, Dieras V, et al. (2011). Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pretreated patients with HER2-overexpressing metastatic breast cancer. Breast Cancer Res Treat 125, 447-455.
    • (2011) Breast Cancer Res Treat , vol.125 , pp. 447-455
    • Jerusalem, G.1    Fasolo, A.2    Dieras, V.3
  • 36
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, and Baylin SB. (2007). The epigenomics of cancer. Cell 128, 683-692.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 37
    • 77954740501 scopus 로고    scopus 로고
    • Metastatic behavior of breast cancer subtypes
    • Kennecke H, Yerushalmi R, Woods R, et al. (2010). Metastatic behavior of breast cancer subtypes. J Clin Oncol 28, 3271-3277.
    • (2010) J Clin Oncol , vol.28 , pp. 3271-3277
    • Kennecke, H.1    Yerushalmi, R.2    Woods, R.3
  • 38
    • 54049096261 scopus 로고    scopus 로고
    • HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
    • Korkaya H, Paulson A, Iovino F, and Wicha MS. (2008). HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 27, 6120-6130.
    • (2008) Oncogene , vol.27 , pp. 6120-6130
    • Korkaya, H.1    Paulson, A.2    Iovino, F.3    Wicha, M.S.4
  • 39
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. (2007). Chromatin modifications and their function. Cell 128, 693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 40
    • 84875169412 scopus 로고    scopus 로고
    • Activation of the unfolded protein response bypasses trastuzumab-mediated inhibition of the PI-3K pathway
    • Kumandan S, Mahadevan NR, Chiu K, Delaney A, and Zanetti M. (2012). Activation of the unfolded protein response bypasses trastuzumab-mediated inhibition of the PI-3K pathway. Cancer Lett 11, 014.
    • (2012) Cancer Lett , vol.11 , pp. 014
    • Kumandan, S.1    Mahadevan, N.R.2    Chiu, K.3    Delaney, A.4    Zanetti, M.5
  • 41
    • 55849099654 scopus 로고    scopus 로고
    • Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers
    • Leary RJ, Lin JC, Cummins J, et al. (2008). Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers. Proc Natl Acad Sci USA 105, 16224-16229.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16224-16229
    • Leary, R.J.1    Lin, J.C.2    Cummins, J.3
  • 42
    • 84859567448 scopus 로고    scopus 로고
    • Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER21:ERa2 breast cancer
    • Liu JC, Voisin V, Bader GD, et al. (2012). Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER21:ERa2 breast cancer. Proc Natl Acad Sci USA 109, 5832-5837.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 5832-5837
    • Liu, J.C.1    Voisin, V.2    Bader, G.D.3
  • 43
    • 38949111440 scopus 로고    scopus 로고
    • MicroRNAs as prognostic indicators and therapeutic targets: Potential effect on breast cancer management
    • Lowery AJ, Miller N, Re M, and Kerin MJ. (2008). MicroRNAs as prognostic indicators and therapeutic targets: Potential effect on breast cancer management. Clin Cancer Res 14, 360-365.
    • (2008) Clin Cancer Res , vol.14 , pp. 360-365
    • Lowery, A.J.1    Miller, N.2    Re, M.3    Kerin, M.J.4
  • 44
    • 84863555312 scopus 로고    scopus 로고
    • Impact of microRNA regulation on variation in human gene expression
    • Lu J, and Clark AG (2012). Impact of microRNA regulation on variation in human gene expression. Genome Res. 22, 1243-1254.
    • (2012) Genome Res , vol.22 , pp. 1243-1254
    • Lu, J.1    Clark, A.G.2
  • 45
    • 84872287335 scopus 로고    scopus 로고
    • Relationship between serum HER2 extracellular domain levels, tissue HER2 expression, and clinico-pathological parameters in early stage breast cancer
    • Ma L, Yang HY, Han XH, et al. (2012). Relationship between serum HER2 extracellular domain levels, tissue HER2 expression, and clinico-pathological parameters in early stage breast cancer. Chin Med J 125, 4104-4110.
    • (2012) Chin Med J , vol.125 , pp. 4104-4110
    • Ma, L.1    Yang, H.Y.2    Han, X.H.3
  • 46
    • 55249092391 scopus 로고    scopus 로고
    • The genomic profile of HER2-amplified breast cancers: The influence of ER status
    • Marchiò C, Natrajan R, Shiu KK, et al. (2008). The genomic profile of HER2-amplified breast cancers: The influence of ER status. J Pathol 216, 399-407.
    • (2008) J Pathol , vol.216 , pp. 399-407
    • Marchiò, C.1    Natrajan, R.2    Shiu, K.K.3
  • 47
    • 79952239863 scopus 로고    scopus 로고
    • Molecular characterization of circulating tumor cells in breast cancer by a liquid bead array hybridization assay
    • Markou A, Strati A, Malamos N, Georgoulias V, and Lianidou ES. (2011). Molecular characterization of circulating tumor cells in breast cancer by a liquid bead array hybridization assay. Clin Chem 57, 421-430.
    • (2011) Clin Chem , vol.57 , pp. 421-430
    • Markou, A.1    Strati, A.2    Malamos, N.3    Georgoulias, V.4    Lianidou, E.S.5
  • 48
    • 33748624597 scopus 로고    scopus 로고
    • Optimized highthroughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies
    • Mattie MD, Benz CC, Bowers J, et al. (2006). Optimized highthroughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol Cancer 19, 5-24.
    • (2006) Mol Cancer , vol.19 , pp. 5-24
    • Mattie, M.D.1    Benz, C.C.2    Bowers, J.3
  • 49
    • 77957198343 scopus 로고    scopus 로고
    • Evaluation of changes in serum protein profiles during neoadjuvant chemotherapy in HER2-positive breast cancer using an LCMALDI-TOF/MS procedure
    • Mazouni C, Baggerly K, Hawke D, et al. (2010). Evaluation of changes in serum protein profiles during neoadjuvant chemotherapy in HER2-positive breast cancer using an LCMALDI-TOF/MS procedure. Proteomics 10, 3525-3532.
    • (2010) Proteomics , vol.10 , pp. 3525-3532
    • Mazouni, C.1    Baggerly, K.2    Hawke, D.3
  • 50
    • 84863221222 scopus 로고    scopus 로고
    • Unmasking epithelial-mesenchymal transition in a breast cancer primary culture: A study report
    • Minafra L, Norata R, Bravatà V, et al. (2012). Unmasking epithelial-mesenchymal transition in a breast cancer primary culture: A study report. BMC Res. Notes 5, 343.
    • (2012) BMC Res. Notes , vol.5 , pp. 343
    • Minafra, L.1    Norata, R.2    Bravatà, V.3
  • 51
    • 79960985354 scopus 로고    scopus 로고
    • HSP90 inhibition is effective in breast cancer: A phase II trial of tanespimycin (17-AAG) plus trastuzumab in patients with HER2-positive metastatic breast cancer progressing on tastuzumab
    • Modi S, Stopeck A, Linden H, et al. (2011). HSP90 inhibition is effective in breast cancer: A phase II trial of tanespimycin (17-AAG) plus trastuzumab in patients with HER2-positive metastatic breast cancer progressing on tastuzumab. Clin Cancer Res 17, 5132-5139.
    • (2011) Clin Cancer Res , vol.17 , pp. 5132-5139
    • Modi, S.1    Stopeck, A.2    Linden, H.3
  • 52
    • 79958706584 scopus 로고    scopus 로고
    • Immunoproteomics of HER2-positive and HER2-negative breast cancer patients with positive lymph nodes
    • Mojtahedi Z, Safaei A, Yousefi Z, and Ghaderi A. (2011). Immunoproteomics of HER2-positive and HER2-negative breast cancer patients with positive lymph nodes. OMICS 15, 409-418.
    • (2011) OMICS , vol.15 , pp. 409-418
    • Mojtahedi, Z.1    Safaei, A.2    Yousefi, Z.3    Ghaderi, A.4
  • 53
    • 77956519036 scopus 로고    scopus 로고
    • Pathway-focused proteomic signatures in HER2-overexpressing breast cancer with a basal-like phenotype: New insights into de novo resistance to trastuzumab (Herceptin
    • Oliveras-Ferraros C, Vazquez-Martin A, Martin-Castilló B, et al. (2010). Pathway-focused proteomic signatures in HER2-overexpressing breast cancer with a basal-like phenotype: New insights into de novo resistance to trastuzumab (Herceptin). Int J Oncol 37, 669-678.
    • (2010) Int J Oncol , vol.37 , pp. 669-678
    • Oliveras-Ferraros, C.1    Vazquez-Martin, A.2    Martin-Castilló, B.3
  • 54
    • 0029884715 scopus 로고    scopus 로고
    • Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization
    • Pauletti G, Godolphin W, Press MF, and Slamon DJ (1996). Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization. Oncogene 13, 63-72.
    • (1996) Oncogene , vol.13 , pp. 63-72
    • Pauletti, G.1    Godolphin, W.2    Press, M.F.3    Slamon, D.J.4
  • 55
    • 79952178148 scopus 로고    scopus 로고
    • C-MYC alterations and association with patient outcome in early-stage HER2-positive breast cancer from the north central cancer treatment group N9831 adjuvant trastuzumab trial
    • Perez EA, Jenkins RB, Dueck AC, et al. (2011). C-MYC alterations and association with patient outcome in early-stage HER2-positive breast cancer from the north central cancer treatment group N9831 adjuvant trastuzumab trial. J Clin Oncol 29, 651-659.
    • (2011) J Clin Oncol , vol.29 , pp. 651-659
    • Perez, E.A.1    Jenkins, R.B.2    Dueck, A.C.3
  • 56
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumors
    • Perou CM, Sørlie T, Eisen MB, et al. (2000). Molecular portraits of human breast tumors. Nature 406, 747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sørlie, T.2    Eisen, M.B.3
  • 57
    • 33846266252 scopus 로고    scopus 로고
    • Prognostic markers in triple-negative breast cancer
    • Rakha EA, El-Sayed ME, Green AR, and Lee AH. (2007). Prognostic markers in triple-negative breast cancer. Cancer 109, 25-32.
    • (2007) Cancer , vol.109 , pp. 25-32
    • Rakha, E.A.1    El-Sayed, M.E.2    Green, A.R.3    Lee, A.H.4
  • 58
    • 81555216077 scopus 로고    scopus 로고
    • Gene expression profiling in breast cancer: Classification, prognostication, and prediction
    • Reis-Filho JS, and Pusztai L. (2011). Gene expression profiling in breast cancer: Classification, prognostication, and prediction. Lancet 378, 1812-1823.
    • (2011) Lancet , vol.378 , pp. 1812-1823
    • Reis-Filho, J.S.1    Pusztai, L.2
  • 59
    • 33749037187 scopus 로고    scopus 로고
    • Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers
    • Rodriguez J, Frigola J, Vendrell E, et al. (2006). Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers. Cancer Res 66, 8462-8468.
    • (2006) Cancer Res , vol.66 , pp. 8462-8468
    • Rodriguez, J.1    Frigola, J.2    Vendrell, E.3
  • 60
    • 67650388533 scopus 로고    scopus 로고
    • Identification of differentially expressed proteins in triple-negative breast carcinomas using DIGE and mass spectrometry
    • Schulz DM, Böllner C, Thomas G, et al. (2009). Identification of differentially expressed proteins in triple-negative breast carcinomas using DIGE and mass spectrometry. Proteome Res 8, 3430-3438.
    • (2009) Proteome Res , vol.8 , pp. 3430-3438
    • Schulz, D.M.1    Böllner, C.2    Thomas, G.3
  • 61
    • 33847738628 scopus 로고    scopus 로고
    • Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
    • Scott GK, Goga A, Bhaumik D, Berger CE, Sullivan CS, and Benz CC. (2007). Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J Biol Chem 282, 1479-1486.
    • (2007) J Biol Chem , vol.282 , pp. 1479-1486
    • Scott, G.K.1    Goga, A.2    Bhaumik, D.3    Berger, C.E.4    Sullivan, C.S.5    Benz, C.C.6
  • 62
    • 33750998490 scopus 로고    scopus 로고
    • A declining plasma fibrinogen alpha fragment identifies HER2-positive breast cancer patients and reverts to normal levels after surgery
    • Shi Q, Harris LN, Lu X, et al. (2006). A declining plasma fibrinogen alpha fragment identifies HER2-positive breast cancer patients and reverts to normal levels after surgery. J Proteome Res 5, 2947-2955.
    • (2006) J Proteome Res , vol.5 , pp. 2947-2955
    • Shi, Q.1    Harris, L.N.2    Lu, X.3
  • 63
    • 77957555408 scopus 로고    scopus 로고
    • Genome profiling of ERBB2-amplified breast cancers
    • Sircoulomb F, Bekhouche I, Finetti P, et al. (2010). Genome profiling of ERBB2-amplified breast cancers. BMC Cancer 10, 539.
    • (2010) BMC Cancer , vol.10 , pp. 539
    • Sircoulomb, F.1    Bekhouche, I.2    Finetti, P.3
  • 64
    • 65549112480 scopus 로고    scopus 로고
    • Alterations in the TOP2A and HER2 genes: Association with adjuvant anthracycline sensitivity in human breast cancers
    • Slamon DJ, and Press MF. (2009). Alterations in the TOP2A and HER2 genes: Association with adjuvant anthracycline sensitivity in human breast cancers. J Natl Cancer Inst 101, 615-618.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 615-618
    • Slamon, D.J.1    Press, M.F.2
  • 65
    • 84870194454 scopus 로고    scopus 로고
    • Pertuzumab for the treatment of patients with previously untreated HER2-positive metastatic breast cancer
    • Smith MB, Reardon J, and Olson EM. (2012). Pertuzumab for the treatment of patients with previously untreated HER2-positive metastatic breast cancer. Drugs Today (Barc) 48, 713-722.
    • (2012) Drugs Today (Barc , vol.48 , pp. 713-722
    • Smith, M.B.1    Reardon, J.2    Olson, E.M.3
  • 66
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sørlie T, Perou CM, Tibshirani R, et al. (2001). Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98, 10869-10874.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10869-10874
    • Sørlie, T.1    Perou, C.M.2    Tibshirani, R.3
  • 67
    • 34250887474 scopus 로고    scopus 로고
    • Taking gene-expression profiling to the clinic: When will molecular signatures become relevant to patient care?
    • Sotiriou C, and Piccart MJ. (2007). Taking gene-expression profiling to the clinic: When will molecular signatures become relevant to patient care? Nat Rev Cancer 7, 545-553.
    • (2007) Nat Rev Cancer , vol.7 , pp. 545-553
    • Sotiriou, C.1    Piccart, M.J.2
  • 68
    • 83355161415 scopus 로고    scopus 로고
    • Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer
    • Staaf J, Jönsson G, Ringnér M, Baldetorp B, and Borg A. (2011). Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer. Breast Cancer Res 13, R129.
    • (2011) Breast Cancer Res , vol.13
    • Staaf, J.1    Jönsson, G.2    Ringnér, M.3    Baldetorp, B.4    Borg, A.5
  • 69
    • 77957940993 scopus 로고    scopus 로고
    • High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer
    • Staaf J, Jönsson G, Ringnér M, et al. (2010). High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer. Breast Cancer Res 12, R25.
    • (2010) Breast Cancer Res , vol.12
    • Staaf, J.1    Jönsson, G.2    Ringnér, M.3
  • 70
    • 2942568164 scopus 로고    scopus 로고
    • Regulation of COX-2 protein expression by Akt in endometrial cancer cells is mediated through NFjB/IjB pathway
    • St-Germain ME, Gagnon V, Parent S, and Asselin E. (2004). Regulation of COX-2 protein expression by Akt in endometrial cancer cells is mediated through NFjB/IjB pathway. Mol Cancer 3, 7.
    • (2004) Mol Cancer , vol.3 , pp. 7
    • St-Germain, M.E.1    Gagnon, V.2    Parent, S.3    Asselin, E.4
  • 71
    • 84861014955 scopus 로고    scopus 로고
    • Salivary protein profiles among HER2/neu-receptor-positive and-negative breast cancer patients: Support for using salivary protein profiles for modeling breast cancer progression
    • Streckfus CF, Arreola D, Edwards C, and Bigler L. (2012). Salivary protein profiles among HER2/neu-receptor-positive and-negative breast cancer patients: Support for using salivary protein profiles for modeling breast cancer progression. J Oncol 2012, 413256.
    • (2012) J Oncol , vol.2012 , pp. 413256
    • Streckfus, C.F.1    Arreola, D.2    Edwards, C.3    Bigler, L.4
  • 72
    • 33847076246 scopus 로고    scopus 로고
    • Genetic and epigenetic regulators of pluripotency
    • Surani MA, Hayashi K, and Hajkova P. (2007). Genetic and epigenetic regulators of pluripotency. Cell 128, 747-762.
    • (2007) Cell , vol.128 , pp. 747-762
    • Surani, M.A.1    Hayashi, K.2    Hajkova, P.3
  • 73
    • 78651324347 scopus 로고    scopus 로고
    • The STRING database in 2011: Functional interaction networks of proteins, globally integrated and scored
    • Szklarczyk D, Franceschini A, Kuhn M, et al. (2011). The STRING database in 2011: Functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res 39, D561-568.
    • (2011) Nucleic Acids Res , vol.39
    • Szklarczyk, D.1    Franceschini, A.2    Kuhn, M.3
  • 74
    • 62349087940 scopus 로고    scopus 로고
    • Association between frequent CpG island methylation and HER2 amplification in human breast cancers
    • Terada K, Okochi-Takada E, Akashi-Tanaka S, et al. (2009). Association between frequent CpG island methylation and HER2 amplification in human breast cancers. Carcinogenesis 30, 466-479.
    • (2009) Carcinogenesis , vol.30 , pp. 466-479
    • Terada, K.1    Okochi-Takada, E.2    Akashi-Tanaka, S.3
  • 75
    • 78149478929 scopus 로고    scopus 로고
    • What do we learn from HER2-positive breast cancer genomic profiles?
    • Theillet C. (2010). What do we learn from HER2-positive breast cancer genomic profiles? Breast Cancer Res 12, 107.
    • (2010) Breast Cancer Res , vol.12 , pp. 107
    • Theillet, C.1
  • 76
    • 0035873962 scopus 로고    scopus 로고
    • Discrepancies in clinical laboratory testing of eligibility for trastuzumab therapy: Apparent immunohistochemical false-positives do not get the message
    • Tubbs RR, Pettay JD, Roche PC, Stoler MH, Jenkins RB, and Grogan TM. (2001). Discrepancies in clinical laboratory testing of eligibility for trastuzumab therapy: Apparent immunohistochemical false-positives do not get the message. J Clin Oncol 19, 2714-2721.
    • (2001) J Clin Oncol , vol.19 , pp. 2714-2721
    • Tubbs, R.R.1    Pettay, J.D.2    Roche, P.C.3    Stoler, M.H.4    Jenkins, R.B.5    Grogan, T.M.6
  • 77
    • 46749150647 scopus 로고    scopus 로고
    • Her-2/neu-induced "cytokine signature" in breast cancer
    • Vazquez-Martin A, Colomer R, Menendez JA. (2008). Her-2/neu-induced "cytokine signature" in breast cancer. Adv Exp Med Biol 617, 311-319.
    • (2008) Adv Exp Med Biol , vol.617 , pp. 311-319
    • Vazquez-Martin, A.1    Colomer, R.2    Menendez, J.A.3
  • 79
    • 0036183416 scopus 로고    scopus 로고
    • Aneusomy 17 in breast cancer: Its role in HER-2/neu protein expression and implication for clinical assessment of HER-2/neu status
    • Wang S, Hossein Saboorian M, Frenkel EP, et al. (2002). Aneusomy 17 in breast cancer: Its role in HER-2/neu protein expression and implication for clinical assessment of HER-2/neu status. Mod Pathol 15, 137-145.
    • (2002) Mod Pathol , vol.15 , pp. 137-145
    • Wang, S.1    Hossein Saboorian, M.2    Frenkel, E.P.3
  • 80
    • 84875137037 scopus 로고    scopus 로고
    • Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast
    • Wee EJH, Peters K, Nair SS, et al. (2012). Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast. Oncogene 20, 82-95.
    • (2012) Oncogene , vol.20 , pp. 82-95
    • Wee, E.J.H.1    Peters, K.2    Nair, S.S.3
  • 81
    • 58149330982 scopus 로고    scopus 로고
    • Meta-analysis of gene expression profiles in breast cancer: Toward a unified understanding of breast cancer subtyping and prognosis signatures
    • Wirapati P, Sotiriou C, Kunkel S, et al. (2008). Meta-analysis of gene expression profiles in breast cancer: Toward a unified understanding of breast cancer subtyping and prognosis signatures. Breast Cancer Res 10, R65.
    • (2008) Breast Cancer Res , vol.10
    • Wirapati, P.1    Sotiriou, C.2    Kunkel, S.3
  • 82
    • 33846568336 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists Guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • Wolff AC, Hammond ME, Schwartz JN, et al. (2007). American Society of Clinical Oncology/College of American Pathologists Guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Arch Pathol Lab Med 131, 18-43.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 18-43
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3
  • 83
    • 77954372744 scopus 로고    scopus 로고
    • FOXO1A is a target for HER2-overexpressing breast tumors
    • Wu Y, Shang X, Sarkissyan M, Slamon D, and Vadgama JV. (2010). FOXO1A is a target for HER2-overexpressing breast tumors. Cancer Res 70, 5475-5485.
    • (2010) Cancer Res , vol.70 , pp. 5475-5485
    • Wu, Y.1    Shang, X.2    Sarkissyan, M.3    Slamon, D.4    Vadgama, J.V.5
  • 84
    • 28644439593 scopus 로고    scopus 로고
    • Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer
    • Zhang D, Tai LK, Wong LL, Chiu LL, Sethi SK, and Koay ES. (2005). Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer. Mol Cell Proteomics 4, 1686-1696.
    • (2005) Mol Cell Proteomics , vol.4 , pp. 1686-1696
    • Zhang, D.1    Tai, L.K.2    Wong, L.L.3    Chiu, L.L.4    Sethi, S.K.5    Koay, E.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.