-
1
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman,J.G. et al. (2003) Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med., 349, 2042-2054.
-
(2003)
N. Engl. J. Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
-
2
-
-
33644846509
-
Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
-
Baylin,S.B. et al. (2006) Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat. Rev. Cancer, 6, 107-116.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 107-116
-
-
Baylin, S.B.1
-
3
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histonemodification maps
-
Esteller,M. (2007) Cancer epigenomics: DNA methylomes and histonemodification maps. Nat. Rev. Genet., 8, 286-298.
-
(2007)
Nat. Rev. Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
4
-
-
33847065486
-
The epigenomics of cancer
-
Jones,P.A. et al. (2007) The epigenomics of cancer. Cell, 128, 683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
-
5
-
-
0032480226
-
DNA hypomethylation leads to elevated mutation rates
-
Chen,R.Z. et al. (1998) DNA hypomethylation leads to elevated mutation rates. Nature, 395, 89-93.
-
(1998)
Nature
, vol.395
, pp. 89-93
-
-
Chen, R.Z.1
-
6
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet,F. et al. (2003) Induction of tumors in mice by genomic hypomethylation. Science, 300, 489-492.
-
(2003)
Science
, vol.300
, pp. 489-492
-
-
Gaudet, F.1
-
7
-
-
10344263962
-
DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas
-
Nakagawa,T. et al. (2005) DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas. J. Urol., 173, 243-246.
-
(2005)
J. Urol
, vol.173
, pp. 243-246
-
-
Nakagawa, T.1
-
8
-
-
33749037187
-
Chromosomal instability correlates with genomewide DNA demethylation in human primary colorectal cancers
-
Rodriguez,J. et al. (2006) Chromosomal instability correlates with genomewide DNA demethylation in human primary colorectal cancers. Cancer Res., 66, 8462-9468.
-
(2006)
Cancer Res
, vol.66
, pp. 8462-9468
-
-
Rodriguez, J.1
-
9
-
-
0033765496
-
Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis - a comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma
-
Kondo,Y. et al. (2000) Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis - a comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma. Hepatology, 32, 970-979.
-
(2000)
Hepatology
, vol.32
, pp. 970-979
-
-
Kondo, Y.1
-
10
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
Toyota,M. et al. (1999) CpG island methylator phenotype in colorectal cancer. Proc. Natl Acad. Sci. USA, 96, 8681-8686.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
-
11
-
-
33745541234
-
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
-
Weisenberger,D.J. et al. (2006) CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat. Genet., 38, 787-793.
-
(2006)
Nat. Genet
, vol.38
, pp. 787-793
-
-
Weisenberger, D.J.1
-
12
-
-
13444270332
-
CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas
-
Abe,M. et al. (2005) CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas. Cancer Res., 65, 828-834.
-
(2005)
Cancer Res
, vol.65
, pp. 828-834
-
-
Abe, M.1
-
13
-
-
33846922849
-
Marked and independent prognostic significance of the CpG island methylator phenotype in neuroblastomas
-
Abe,M. et al. (2007) Marked and independent prognostic significance of the CpG island methylator phenotype in neuroblastomas. Cancer Lett., 247, 253-258.
-
(2007)
Cancer Lett
, vol.247
, pp. 253-258
-
-
Abe, M.1
-
14
-
-
0022406444
-
Amplification of a novel v-erb -related gene in a human mammary carcinoma
-
King,C.R. et al. (1985) Amplification of a novel v-erb -related gene in a human mammary carcinoma. Science, 229, 974-976.
-
(1985)
Science
, vol.229
, pp. 974-976
-
-
King, C.R.1
-
15
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon,D.J. et al. (1987) Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science, 235, 177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
-
16
-
-
0037233233
-
Trastuzumab, an appropriate first-line single-agent therapy for HER2-overexpressing metastatic breast cancer
-
Arteaga,C.L. (2003) Trastuzumab, an appropriate first-line single-agent therapy for HER2-overexpressing metastatic breast cancer. Breast Cancer Res., 5, 96-100.
-
(2003)
Breast Cancer Res
, vol.5
, pp. 96-100
-
-
Arteaga, C.L.1
-
17
-
-
34347395733
-
Trastuzumab - mechanism of action and use in clinical practice
-
Hudis,C.A. (2007) Trastuzumab - mechanism of action and use in clinical practice. N. Engl. J. Med., 357, 39-51.
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 39-51
-
-
Hudis, C.A.1
-
18
-
-
22244479985
-
Identification of 20 genes aberrantly methylated in human breast cancers
-
Miyamoto,K. et al. (2005) Identification of 20 genes aberrantly methylated in human breast cancers. Int. J. Cancer, 116, 407-414.
-
(2005)
Int. J. Cancer
, vol.116
, pp. 407-414
-
-
Miyamoto, K.1
-
19
-
-
35548974227
-
Lack of association between CpG island methylator phenotype in human gastric cancers and methylation in their background non-cancerous gastric mucosae
-
Enomoto,S. et al. (2007) Lack of association between CpG island methylator phenotype in human gastric cancers and methylation in their background non-cancerous gastric mucosae. Cancer Sci., 98, 1853-1861.
-
(2007)
Cancer Sci
, vol.98
, pp. 1853-1861
-
-
Enomoto, S.1
-
20
-
-
33847070442
-
The role of chromatin during transcription
-
Li,B. et al. (2007) The role of chromatin during transcription. Cell, 128, 707-719.
-
(2007)
Cell
, vol.128
, pp. 707-719
-
-
Li, B.1
-
21
-
-
14644396228
-
Detection and interpretation of altered methylation patterns in cancer cells
-
Ushijima,T. (2005) Detection and interpretation of altered methylation patterns in cancer cells. Nat. Rev. Cancer, 5, 223-231.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 223-231
-
-
Ushijima, T.1
-
22
-
-
33645529696
-
General rules for clinical and pathological recording of breast cancer 2005
-
Sakamoto,G. et al. (2005) General rules for clinical and pathological recording of breast cancer 2005. Breast Cancer, 12 (suppl.), S1-S27.
-
(2005)
Breast Cancer
, vol.12
, Issue.SUPPL.
-
-
Sakamoto, G.1
-
23
-
-
3242885344
-
Decreased expression of the seven ARP2/ 3 complex genes in human gastric cancers
-
Kaneda,A. et al. (2004) Decreased expression of the seven ARP2/ 3 complex genes in human gastric cancers. Cancer Lett., 212 203-210.
-
(2004)
Cancer Lett
, vol.212
, pp. 203-210
-
-
Kaneda, A.1
-
24
-
-
59149086374
-
Tyrosine1248-phosphorylated HER2 expression and HER2 gene amplification in female invasive ductal carcinomas
-
Taniyama,K. et al. (2008) Tyrosine1248-phosphorylated HER2 expression and HER2 gene amplification in female invasive ductal carcinomas. Breast Cancer, 15, 231-240.
-
(2008)
Breast Cancer
, vol.15
, pp. 231-240
-
-
Taniyama, K.1
-
25
-
-
0033561360
-
Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein
-
Van Rompay,A.R. et al. (1999) Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein. Eur. J. Biochem., 261, 509-517.
-
(1999)
Eur. J. Biochem
, vol.261
, pp. 509-517
-
-
Van Rompay, A.R.1
-
27
-
-
33745500432
-
CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies
-
Ogino,S. et al. (2006) CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies. Gut, 55, 1000-1006.
-
(2006)
Gut
, vol.55
, pp. 1000-1006
-
-
Ogino, S.1
-
28
-
-
31544435739
-
Breast cancer DNA methylation profiles in cancer cells and tumor stroma: Association with HER-2/neu status in primary breast cancer
-
Fiegl,H. et al. (2006) Breast cancer DNA methylation profiles in cancer cells and tumor stroma: Association with HER-2/neu status in primary breast cancer. Cancer Res., 66, 29-33.
-
(2006)
Cancer Res
, vol.66
, pp. 29-33
-
-
Fiegl, H.1
-
29
-
-
0035421454
-
Patterns of her-2/neu amplification and overexpression in primary and metastatic breast cancer
-
Simon,R. et al. (2001) Patterns of her-2/neu amplification and overexpression in primary and metastatic breast cancer. J. Natl Cancer Inst., 93, 1141-1146.
-
(2001)
J. Natl Cancer Inst
, vol.93
, pp. 1141-1146
-
-
Simon, R.1
-
30
-
-
33646949481
-
DNA hypermethylation in breast cancer and its association with clinicopathological features
-
Li,S. et al. (2006) DNA hypermethylation in breast cancer and its association with clinicopathological features. Cancer Lett., 237, 272-280.
-
(2006)
Cancer Lett
, vol.237
, pp. 272-280
-
-
Li, S.1
-
31
-
-
2542629617
-
Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen
-
Widschwendter,M. et al. (2004) Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen. Cancer Res., 64, 3807-3813.
-
(2004)
Cancer Res
, vol.64
, pp. 3807-3813
-
-
Widschwendter, M.1
-
32
-
-
36549029229
-
Correlation between CpG methylation profiles and hormone receptor status in breast cancers
-
Feng,W. et al. (2007) Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast Cancer Res., 9, R57.
-
(2007)
Breast Cancer Res
, vol.9
-
-
Feng, W.1
|