HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicin-based dose-dense sequential chemotherapy

Journal of Translational Medicine

Volumn 10, Issue 1, 2012, Pages

  Fountzilas, George ^a   Valavanis, Christos ^b   Kotoula, Vassiliki ^a   Eleftheraki, Anastasia G ^c   Kalogeras, Konstantine T ^a,c   Tzaida, Olympia ^b   Batistatou, Anna ^d   Kronenwett, Ralf ^e,k   Wirtz, Ralph M ^e,l   Bobos, Mattheos ^a   Timotheadou, Eleni ^a   Soupos, Nikolaos ^f   Pentheroudakis, George ^d   Gogas, Helen ^f   Vlachodimitropoulos, Dimitrios ^f   Polychronidou, Genovefa ^a   Aravantinos, Gerasimos ^g   Koutras, Angelos ^h   Christodoulou, Christos ⁱ   Pectasides, Dimitrios ^j   Arapantoni, Petroula ^b   more..

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b METAXA CANCER HOSPITAL   (Greece)

^c Hellenic Cooperative Oncology Group   (Greece)

^d UNIVERSITY HOSPITAL OF IOANNINA   (Greece)

^e SIEMENS AG   (Germany)

^f UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^g AGII ANARGIRI CANCER HOSPITAL   (Greece)

^h UNIVERSITY OF PATRAS   (Greece)

ⁱ METROPOLITAN HOSPITAL   (Greece)

^j HIPPOKRATION HOSPITAL   (Greece)

^k Sividon Diagnostics GmbH   (Germany)

^l STRATIFYER Molecular Pathology GmbH   (Germany)

more..

Author keywords

Anthracyclines; Cish; Early breast cancer; Gene amplification; Her2; Mrna expression; Randomized study; Taxanes; Top2a

Indexed keywords

CYCLOPHOSPHAMIDE; DNA TOPOISOMERASE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIRUBICIN; FLUOROURACIL; GRANULOCYTE COLONY STIMULATING FACTOR; KI 67 ANTIGEN; MESSENGER RNA; METHOTREXATE; PACLITAXEL; PROTEIN; TOPOISOMERASE II ALPHA; TOPOLLA PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; DNA BINDING PROTEIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE II ALPHA; ESTROGEN RECEPTOR; HER2 PROTEIN, HUMAN; PARAFFIN; PROGESTERONE RECEPTOR; TUMOR ANTIGEN;

ADJUVANT THERAPY; ARTICLE; BREAST CARCINOMA; CANCER ADJUVANT THERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER PATIENT; CANCER SURVIVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DRUG DOSE SEQUENCE; FEMALE; GENE; GENE AMPLIFICATION; GENE EXPRESSION; HER2 GENE; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MAJOR CLINICAL STUDY; MULTIPLE CYCLE TREATMENT; NUCLEOTIDE SEQUENCE; OVERALL SURVIVAL; PHASE 3 CLINICAL TRIAL; POSTOPERATIVE CARE; PROGNOSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOP2A GENE; TREATMENT RESPONSE; ADJUVANT CHEMOTHERAPY; ADULT; AGED; BREAST TUMOR; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; TISSUE FIXATION; TREATMENT OUTCOME; TUMOR GENE;

ADULT; AGED; ANTIBIOTICS, ANTINEOPLASTIC; ANTIGENS, NEOPLASM; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIRUBICIN; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEOPLASM; HUMANS; KI-67 ANTIGEN; MIDDLE AGED; MULTIVARIATE ANALYSIS; PARAFFIN EMBEDDING; PROPORTIONAL HAZARDS MODELS; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; RISK FACTORS; RNA, MESSENGER; TISSUE FIXATION; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84855568731     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-10-10     Document Type: Article

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