Assessing serum cytokine profiles in breast cancer patients receiving a HER2/neu vaccine using Luminex® technology

Oncology Reports

Volumn 17, Issue 3, 2007, Pages 687-694

  Dehqanzada, Zia A ^a,b   Storrer, Catherine E ^a   Hueman, Matthew T ^a,b   Foley, Rebecca J ^a   Harris, Katie A ^a   Jama, Yusuf H ^a   Shriver, Craig D ^b   Ponniah, Sathibalan ^a   Peoples, George E ^a,b  

^a HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE   (United States)

^b WALTER REED ARMY MEDICAL CENTER   (United States)

Author keywords

HER2 neu E75 peptide vaccine; Luminex multiplex assay; Serum cytokines

Indexed keywords

CANCER VACCINE; CYTOKINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ARTICLE; BLOOD; BREAST TUMOR; CLINICAL TRIAL; COMPARATIVE STUDY; FEMALE; HUMAN; IMMUNOLOGY; LYMPH NODE METASTASIS; MIDDLE AGED; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; TUMOR RECURRENCE;

BREAST NEOPLASMS; CANCER VACCINES; CYTOKINES; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; RECEPTOR, ERBB-2;

EID: 34247890015     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.17.3.687     Document Type: Article

References (23)

1. Bast RC Jr, Ravdin P, Hayes DF, Bates S, Fritsche H, Jessup JM, Kemeny N, Locker GY, Mennel RG and Somerfield MR: 2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 19: 1865-1878, 2001. (Pubitemid 32230890)
2. Petricoin EF, Ardekani AM, Hitt BA, Levine PJ, Fusaro VA, Steinberg SM, Mills GB, Simone C, Fishman DA, Kohn EC and Liotta LA: Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359: 572-577, 2002. (Pubitemid 34178440)
3. Alexe G, Alexe S, Liotta LA, Petricoin E, Reiss M and Hammer PL: Ovarian cancer detection by logical analysis of proteomic data. Proteomics 4: 766-783, 2004. (Pubitemid 38339155)
4. Bellisario R, Colinas RJ and Pass KA: Simultaneous measurement of thyroxine and thyrotropin from newborn dried blood-spot specimens using a multiplexed fluorescent microsphere immunoassay. Clin Chem 46: 1422-1424, 2000.
5. Bellisario R, Colinas RJ and Pass KA: Simultaneous measurement of antibodies to three HIV-1 antigens in newborn dried bloodspot specimens using a multiplexed microsphere-based immunoassay. Early Hum Dev 64: 21-25, 2001. (Pubitemid 32530068)
6. Carson RT and Vignali DA: Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay. J Immunol Methods 227: 41-52, 1999. (Pubitemid 29408703)
7. Chen J, Iannone MA, Li M-S, Taylor JD, Rivers P, Nelsen AJ, Slentz-Kesler KA, Roses A and Weiner MP: A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension. Genome Res 10: 549-557, 2000. (Pubitemid 30259430)
8. Taylor JD, Briley D, Nguyen Q, Long K, Iannone MA, Li M-S, Ye F, Afshari A, Lai E, Wagner M, Chen J and Weiner MP: Flow cytometric platform for high-throughput single nucleotide polymorphism analysis. Biotechniques 30: 661-669, 2001. (Pubitemid 32202872)
9. Peoples GE, Gurney JM, Heuman MT, Woll MM, Ryan GB, Storrer CE, Fisher C, Shriver CD, Ioannides CG and Ponniah S: Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients. J Clin Oncol 23: 7536-7545, 2005. (Pubitemid 46291817)
10. Hueman MT, Dehqanzada ZA, Novak TE, Gurney JM, Woll MM, Ryan GB, Storrer CE, Fisher C, McLeod DG, Ioannides CG, Ponniah S and Peoples GE: Clinical trial results of a HER2/neu peptide (E75) vaccine for the prevention of PSA recurrence in high-risk prostate cancer patients. Clin Cancer Res 11: 7470-7479, 2005. (Pubitemid 41507708)
11. Lee TD: Distribution of HLA antigens in North American Caucasians, North American Blacks and Orientals. In: The HLA System. Lee TD (ed). Springer-Verlag, New York, pp141-178, 1990.
12. Woll MM, Fisher CM, Ryan GB, Gurney JM, Storrer CE, Ioannides CG, Shriver CD, Moul JW, McLeod DG, Ponniah S and Peoples GE: Direct measurement of peptide-specific CD8+ T cells using HLA-A2:Ig dimer for monitoring the in vivo immune response to a HER2/neu vaccine in breast and prostate cancer patients. J Clin Immunol 24: 449-461, 2004. (Pubitemid 39005578)
13. Halak BK, Maguire HC and Lattime EC: Tumor-induced interleukin-10 inhibits type 1 immune responses directed at a tumor antigen as well as a non-tumor antigen present at the tumor site. Cancer Res 59: 911-917, 1999. (Pubitemid 29086748)
14. Staveley-O'Carroll K, Sotomayor E, Montgomery J, Borrello I, Hwang L, Fein S, Pardoll D and Levitsky H: Induction of antigen-specific T cell anergy: an early event in the course of tumor progression. Proc Natl Acad Sci USA 95: 1178-1183, 1998. (Pubitemid 28124932)
15. Melchionda F, McKirdy MK, Medeiros F, Fry TJ and Mackall CL: Escape from immune surveillance does not result in tolerance to tumor-associated antigens. J Immunother 27: 329-338, 2004. (Pubitemid 39121921)
16. Lebrecht A, Grimm C, Lantzsch T, Ludwig E, Hefler L, Ulbrich E and Koelbl H: Monocyte chemoattractant protein-1 serum levels in patients with breast cancer. Tumor Biol 25: 14-17, 2004. (Pubitemid 38822766)
17. Hefler L, Tempfer C, Heinze G, Mayerhofer K, Breitenecker G, Leodolter S, Reinthaller A and Kainz C: Monocyte chemoattractant protein-1 serum levels in ovarian cancer patients. Br J Cancer 81: 855-859, 1999. (Pubitemid 29504697)
18. Jose PJ, Griffiths-Johnson DA, Collins PD, Walsh DT, Moqbel R, Totty NF, Truong O, Hsuan JJ and Williams TJ: Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. J Exp Med 179: 881-887, 1994. (Pubitemid 24065646)
19. Leonard EJ and Yoshimura T: Human monocyte chemoattractant protein-1 (MCP-1). Immunol Today 11: 97-101, 1990. (Pubitemid 20062717)
20. Ogilvie P, Bardi G, Clark-Lewis I, Baggiolini M and Uguccioni M: Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5. Blood 97: 1920-1924, 2001. (Pubitemid 32239067)
21. Saji H, Koike M, Yamori T, Saji S, Seiki M, Matsushima K and Toi M: Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma. Cancer 92: 1085-1091, 2001. (Pubitemid 32861655)
22. Salcedo R, Ponce ML, Young HA, Wasserman K, Ward JM, Kleinman HK, Oppenheim JJ and Murphy WJ: Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood 96: 34-40, 2000. (Pubitemid 30456447)
23. Gouon-Evans V, Lin EY and Pollard JW: Requirement of macrophages and eosinophils and their cytokines/chemokines for mammary gland development. Breast Cancer Res 4: 155-164, 2002. (Pubitemid 35012324)