Region-specific neuron and synapse loss in the hippocampus of APP SL/PS1 knock-in mice

Translational Neuroscience

Volumn 4, Issue 1, 2013, Pages 8-19

  Brasnjevic, Ivona ^a,b   Lardenoije, Roy ^a   Schmitz, Christoph ^c   Van Der Kolk, Nicolien ^a,b   Dickstein, Dara L ^d   Takahashi, Hisaaki ^e   Hof, Patrick R ^d   Steinbusch, Harry W M ^a,b   Rutten, Bart P F ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b European Graduate School of Neuroscience   (Netherlands)

^c UNIVERSITY OF MUNICH   (Germany)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Hippocampus; Image analysis; Neuron loss; Presenilin 1; Stereology; Synapse loss

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; PRESENILIN 1; SYNAPTOPHYSIN;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN REGION; CELL COUNT; CELL GRANULE; CELL LOSS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENTATE GYRUS; FEMALE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; KNOCKOUT MOUSE; MALE; MOLECULAR PATHOLOGY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION;

EID: 84874918831     PISSN: 20813856     EISSN: 20816936     Source Type: Journal    
DOI: 10.2478/s13380-013-0111-8     Document Type: Article

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