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Volumn 14, Issue 1, 2013, Pages 87-99

The vascular endothelium in diabetes - A therapeutic target?

Author keywords

Endothelin; Endothelium; Insulin; Nitric oxide; Therapy; Vasodilation

Indexed keywords

ACIPIMOX; ADVANCED GLYCATION END PRODUCT; ALPHA GLUCOSIDASE INHIBITOR; BENFOTIAMINE; CATECHOL METHYLTRANSFERASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EPIGALLOCATECHIN GALLATE; FISH OIL; GEMFIBROZIL; INSULIN SENSITIZING AGENT; METFORMIN; N(G) METHYLARGININE; N(G),N(G) DIMETHYLARGININE; NICOTINIC ACID; PIOGLITAZONE; PRASTERONE; RESVERATROL;

EID: 84874662738     PISSN: 13899155     EISSN: 15732606     Source Type: Journal    
DOI: 10.1007/s11154-013-9237-9     Document Type: Review
Times cited : (31)

References (194)
  • 1
    • 0030839740 scopus 로고    scopus 로고
    • Role of blood flow in the regulation of muscle glucose uptake
    • DOI 10.1146/annurev.nutr.17.1.487
    • Baron AD, Clark MG. Role of blood flow in the regulation of muscle glucose uptake. Annu Rev Nutr. 1997;17:487-99. (Pubitemid 27328810)
    • (1997) Annual Review of Nutrition , vol.17 , pp. 487-499
    • Baron, A.D.1    Clark, M.G.2
  • 2
    • 0034037949 scopus 로고    scopus 로고
    • Interaction between insulin sensitivity and muscle perfusion on glucose uptake in human skeletal muscle: Evidence for capillary recruitment
    • Baron AD, Tarshoby M, Hook G, Lazaridis EN, Cronin J, Johnson A, et al. Interaction between insulin sensitivity and muscle perfusion on glucose uptake in human skeletal muscle: evidence for capillary recruitment. Diabetes. 2000;49(5):768-74. (Pubitemid 30339992)
    • (2000) Diabetes , vol.49 , Issue.5 , pp. 768-774
    • Baron, A.D.1    Tarshoby, M.2    Hook, G.3    Lazaridis, E.N.4    Cronin, J.5    Johnson, A.6    Steinberg, H.O.7
  • 3
    • 0031977203 scopus 로고    scopus 로고
    • Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance. Effects of troglitazone
    • DOI 10.1007/s001250050948
    • Tack CJ, Ong MK, Lutterman JA, Smits P. Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance. Effects of troglitazone. Diabetologia. 1998;41(5):569-76. (Pubitemid 28206828)
    • (1998) Diabetologia , vol.41 , Issue.5 , pp. 569-576
    • Tack, C.J.J.1    Ong, M.K.E.2    Lutterman, J.A.3    Smits, P.4
  • 4
    • 64149117276 scopus 로고    scopus 로고
    • The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action
    • 19283361 1:CAS:528:DC%2BD1MXktVOktbY%3D 10.1007/s00125-009-1313-z
    • Barrett EJ, Eggleston EM, Inyard AC, Wang H, Li G, Chai W, et al. The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action. Diabetologia. 2009;52(5):752-64.
    • (2009) Diabetologia , vol.52 , Issue.5 , pp. 752-764
    • Barrett, E.J.1    Eggleston, E.M.2    Inyard, A.C.3    Wang, H.4    Li, G.5    Chai, W.6
  • 6
    • 0033536236 scopus 로고    scopus 로고
    • Insulin signaling in the arterial wall
    • PII S0002914999003537
    • Hsueh WA, Law RE. Insulin signaling in the arterial wall. Am J Cardiol. 1999;84(1A):21J-4J. (Pubitemid 29334856)
    • (1999) American Journal of Cardiology , vol.84 , Issue.1
    • Hsueh, W.A.1    Law, R.E.2
  • 7
    • 0036020513 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells
    • DOI 10.1210/me.2002-0074
    • Montagnani M, Ravichandran LV, Chen H, Esposito DL, Quon MJ. Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells. Mol Endocrinol. 2002;16(8):1931-42. (Pubitemid 34828099)
    • (2002) Molecular Endocrinology , vol.16 , Issue.8 , pp. 1931-1942
    • Montagnani, M.1    Ravichandran, L.V.2    Chen, H.3    Esposito, D.L.4    Quon, M.J.5
  • 8
    • 0141671792 scopus 로고    scopus 로고
    • Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium
    • Vincent MA, Montagnani M, Quon MJ. Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium. Curr Diabetes Rep. 2003;3(4):279-88. (Pubitemid 38906783)
    • (2003) Current Diabetes Reports , vol.3 , Issue.4 , pp. 279-288
    • Vincent, M.A.1    Montagnani, M.2    Quon, M.J.3
  • 9
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H, et al. Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation. 2000;101(13):1539-45. (Pubitemid 30180890)
    • (2000) Circulation , vol.101 , Issue.13 , pp. 1539-1545
    • Zeng, G.1    Nystrom, F.H.2    Ravichandran, L.V.3    Cong, L.-N.4    Kirby, M.5    Mostowski, H.6    Quon, M.J.7
  • 10
    • 0035743353 scopus 로고    scopus 로고
    • Insulin action in the vasculature: Physiology and pathophysiology
    • DOI 10.1159/000051074
    • Mather K, Anderson TJ, Verma S. Insulin action in the vasculature: physiology and pathophysiology. J Vasc Res. 2001;38(5):415-22. (Pubitemid 34701454)
    • (2001) Journal of Vascular Research , vol.38 , Issue.5 , pp. 415-422
    • Mather, K.1    Anderson, T.J.2    Verma, S.3
  • 12
    • 0042521215 scopus 로고    scopus 로고
    • Insulin-mediated capillary recruitment in skeletal muscle: Is this a mediator of insulin action on glucose metabolism?
    • Rattigan S, Barrett EJ, Clark MG. Insulin-mediated capillary recruitment in skeletal muscle: is this a mediator of insulin action on glucose metabolism? Curr Diabetes Rep. 2003;3(3):195-200. (Pubitemid 38906772)
    • (2003) Current Diabetes Reports , vol.3 , Issue.3 , pp. 195-200
    • Rattigan, S.1    Barrett, E.J.2    Clark, M.G.3
  • 16
    • 0028030813 scopus 로고
    • Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release
    • 8083357 1:CAS:528:DyaK2cXlslWjsLY%3D 10.1172/JCI117433
    • Steinberg HO, Brechtel G, Johnson A, Fineberg N, Baron AD. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Investig. 1994;94(3):1172-9.
    • (1994) J Clin Investig , vol.94 , Issue.3 , pp. 1172-1179
    • Steinberg, H.O.1    Brechtel, G.2    Johnson, A.3    Fineberg, N.4    Baron, A.D.5
  • 17
    • 0033983242 scopus 로고    scopus 로고
    • Insulin action is associated with endothelial function in hypertension and type 2 diabetes
    • Cleland SJ, Petrie JR, Small M, Elliott HL, Connell JM. Insulin action is associated with endothelial function in hypertension and type 2 diabetes. Hypertension. 2000;35(1 Pt 2):507-11. (Pubitemid 30054225)
    • (2000) Hypertension , vol.35 , Issue.1 , pp. 507-511
    • Cleland, S.J.1    Petrie, J.R.2    Small, M.3    Elliott, H.L.4    Connell, J.M.C.5
  • 18
    • 79960768692 scopus 로고    scopus 로고
    • Insulin regulates its own delivery to skeletal muscle by feed-forward actions on the vasculature
    • 21610226 1:CAS:528:DC%2BC3MXhtFSqurvF 10.1152/ajpendo.00186.2011
    • Barrett EJ, Wang H, Upchurch CT, Liu Z. Insulin regulates its own delivery to skeletal muscle by feed-forward actions on the vasculature. Am J Physiol Endocrinol Metab. 2011;301(2):E252-63.
    • (2011) Am J Physiol Endocrinol Metab , vol.301 , Issue.2
    • Barrett, E.J.1    Wang, H.2    Upchurch, C.T.3    Liu, Z.4
  • 20
    • 85027926370 scopus 로고    scopus 로고
    • Leptin potentiates endothelium-dependent relaxation by inducing endothelial expression of neuronal NO synthase
    • 22580898 1:CAS:528:DC%2BC38XpvV2mtrg%3D 10.1161/ATVBAHA.112.251140
    • Benkhoff S, Loot AE, Pierson I, Sturza A, Kohlstedt K, Fleming I, et al. Leptin potentiates endothelium-dependent relaxation by inducing endothelial expression of neuronal NO synthase. Arterioscler Thromb Vasc Biol. 2012;32(7):1605-12.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , Issue.7 , pp. 1605-1612
    • Benkhoff, S.1    Loot, A.E.2    Pierson, I.3    Sturza, A.4    Kohlstedt, K.5    Fleming, I.6
  • 21
    • 0242581695 scopus 로고    scopus 로고
    • Adiponectin Stimulates Production of Nitric Oxide in Vascular Endothelial Cells
    • DOI 10.1074/jbc.M307878200
    • Chen H, Montagnani M, Funahashi T, Shimomura I, Quon MJ. Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem. 2003;278(45):45021-6. (Pubitemid 37377262)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.45 , pp. 45021-45026
    • Chen, H.1    Montagnani, M.2    Funahashi, T.3    Shimomura, I.4    Quon, M.J.5
  • 25
    • 79956119675 scopus 로고    scopus 로고
    • The possible protective role of glucagon-like peptide 1 on endothelium during the meal and evidence for an "endothelial resistance" to glucagon-like peptide 1 in diabetes
    • 21273492 1:CAS:528:DC%2BC3MXjvFOgs7g%3D 10.2337/dc10-1949
    • Ceriello A, Esposito K, Testa R, Bonfigli AR, Marra M, Giugliano D. The possible protective role of glucagon-like peptide 1 on endothelium during the meal and evidence for an "endothelial resistance" to glucagon-like peptide 1 in diabetes. Diabetes Care. 2011;34(3):697-702.
    • (2011) Diabetes Care , vol.34 , Issue.3 , pp. 697-702
    • Ceriello, A.1    Esposito, K.2    Testa, R.3    Bonfigli, A.R.4    Marra, M.5    Giugliano, D.6
  • 26
    • 43749124472 scopus 로고    scopus 로고
    • Endothelial dysfunction in normal and abnormal glucose metabolism
    • 18230954 1:CAS:528:DC%2BD1MXhsl2jsrc%3D 10.1159/000115120
    • Esper RJ, Vilarino JO, Machado RA, Paragano A. Endothelial dysfunction in normal and abnormal glucose metabolism. Adv Cardiol. 2008;45:17-43.
    • (2008) Adv Cardiol , vol.45 , pp. 17-43
    • Esper, R.J.1    Vilarino, J.O.2    Machado, R.A.3    Paragano, A.4
  • 27
    • 79955706455 scopus 로고    scopus 로고
    • Contributions of dysglycaemia, obesity, and insulin resistance to impaired endothelium-dependent vasodilation in humans
    • 1:CAS:528:DC%2BC3MXmslWhtbs%3D 10.1002/dmrr.1183
    • Han KA, Patel Y, Lteif AA, Chisholm R, Mather KJ. Contributions of dysglycaemia, obesity, and insulin resistance to impaired endothelium-dependent vasodilation in humans. Diabetes Metabol Res Rev. 2011;27(4):354-61.
    • (2011) Diabetes Metabol Res Rev , vol.27 , Issue.4 , pp. 354-361
    • Han, K.A.1    Patel, Y.2    Lteif, A.A.3    Chisholm, R.4    Mather, K.J.5
  • 29
    • 0033165758 scopus 로고    scopus 로고
    • Hyperglycemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery
    • 10400004 1:STN:280:DyaK1MzisFGqsw%3D%3D 10.1016/S0735-1097(99)00168-0
    • Kawano H, Motoyama T, Hirashima O, Hirai N, Miyao Y, Sakamoto T, et al. Hyperglycemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery. J Am Coll Cardiol. 1999;34(1):146-54.
    • (1999) J Am Coll Cardiol , vol.34 , Issue.1 , pp. 146-154
    • Kawano, H.1    Motoyama, T.2    Hirashima, O.3    Hirai, N.4    Miyao, Y.5    Sakamoto, T.6
  • 31
    • 79955725780 scopus 로고    scopus 로고
    • Effects of insulin and oral anti-diabetic agents on glucose metabolism, vascular dysfunction and skeletal muscle inflammation in type 2 diabetic subjects
    • 1:CAS:528:DC%2BC3MXmslWhtbk%3D 10.1002/dmrr.1185
    • Joya-Galeana J, Fernandez M, Cervera A, Reyna S, Ghosh S, Triplitt C, et al. Effects of insulin and oral anti-diabetic agents on glucose metabolism, vascular dysfunction and skeletal muscle inflammation in type 2 diabetic subjects. Diabetes Metabol Res Rev. 2011;27(4):373-82.
    • (2011) Diabetes Metabol Res Rev , vol.27 , Issue.4 , pp. 373-382
    • Joya-Galeana, J.1    Fernandez, M.2    Cervera, A.3    Reyna, S.4    Ghosh, S.5    Triplitt, C.6
  • 32
    • 63649097810 scopus 로고    scopus 로고
    • Effects of the alpha glucosidase inhibitor acarbose on endothelial function after a mixed meal in newly diagnosed type 2 diabetes
    • 1:CAS:528:DC%2BD1MXktVWns7g%3D 10.1055/s-0028-1103276
    • Pistrosch F, Schaper F, Passauer J, Koehler C, Bornstein SR, Hanefeld M. Effects of the alpha glucosidase inhibitor acarbose on endothelial function after a mixed meal in newly diagnosed type 2 diabetes. Horm Metab Res Horm Stoffwechselforschung Horm Metab. 2009;41(2):104-8.
    • (2009) Horm Metab Res Horm Stoffwechselforschung Horm Metab , vol.41 , Issue.2 , pp. 104-108
    • Pistrosch, F.1    Schaper, F.2    Passauer, J.3    Koehler, C.4    Bornstein, S.R.5    Hanefeld, M.6
  • 33
    • 83555168228 scopus 로고    scopus 로고
    • Effect of 3-month repeated administration of miglitol on vascular endothelial function in patients with diabetes mellitus and coronary artery disease
    • 21944671 1:CAS:528:DC%2BC3MXhs1els7vJ 10.1016/j.amjcard.2011.08.005
    • Emoto T, Sawada T, Hashimoto M, Kageyama H, Terashita D, Mizoguchi T, et al. Effect of 3-month repeated administration of miglitol on vascular endothelial function in patients with diabetes mellitus and coronary artery disease. Am J Cardiol. 2012;109(1):42-6.
    • (2012) Am J Cardiol , vol.109 , Issue.1 , pp. 42-46
    • Emoto, T.1    Sawada, T.2    Hashimoto, M.3    Kageyama, H.4    Terashita, D.5    Mizoguchi, T.6
  • 34
    • 77954501338 scopus 로고    scopus 로고
    • Single administration of alpha-glucosidase inhibitors on endothelial function and incretin secretion in diabetic patients with coronary artery disease - Juntendo University trial: Effects of miglitol on endothelial vascular reactivity in type 2 diabetic patients with coronary heart disease (J-MACH)
    • 1:CAS:528:DC%2BC3cXpvFans7c%3D
    • Hiki M, Shimada K, Kiyanagi T, Fukao K, Hirose K, Ohsaka H, et al. Single administration of alpha-glucosidase inhibitors on endothelial function and incretin secretion in diabetic patients with coronary artery disease - Juntendo University trial: effects of miglitol on endothelial vascular reactivity in type 2 diabetic patients with coronary heart disease (J-MACH). Circ J Off J Jpn Circ Soc. 2010;74(7):1471-8.
    • (2010) Circ J off J Jpn Circ Soc , vol.74 , Issue.7 , pp. 1471-1478
    • Hiki, M.1    Shimada, K.2    Kiyanagi, T.3    Fukao, K.4    Hirose, K.5    Ohsaka, H.6
  • 35
    • 0030001931 scopus 로고    scopus 로고
    • The effect of acarbose on insulin sensitivity in subjects with impaired glucose tolerance
    • 1:STN:280:DyaK283ktl2ntw%3D%3D
    • Chiasson JL. The effect of acarbose on insulin sensitivity in subjects with impaired glucose tolerance. Diabet Med J Br Diabet Assoc. 1996;13(3 Suppl 2):S23-4.
    • (1996) Diabet Med J Br Diabet Assoc , vol.13 , Issue.3 SUPPL. 2
    • Chiasson, J.L.1
  • 36
    • 0031888120 scopus 로고    scopus 로고
    • Effects voglibose on glycemic excursions, insulin secretion, and insulin sensitivity in non-insulin-treated NIDDM patients
    • Matsumoto K, Yano M, Miyake S, Ueki Y, Yamaguchi Y, Akazawa S, et al. Effects of voglibose on glycemic excursions, insulin secretion, and insulin sensitivity in non-insulin-treated NIDDM patients. Diabetes Care. 1998;21(2):256-60. (Pubitemid 28079434)
    • (1998) Diabetes Care , vol.21 , Issue.2 , pp. 256-260
    • Matsumoto, K.1    Yano, M.2    Miyake, S.3    Ueki, Y.4    Yamaguchi, Y.5    Akazawa, S.6    Tominaga, Y.7
  • 37
    • 84855992711 scopus 로고    scopus 로고
    • SGLT-2 inhibitors in development for type 2 diabetes treatment
    • 10.1900/RDS.2011.8.348
    • Bhartia M, Tahrani AA, Barnett AH. SGLT-2 inhibitors in development for type 2 diabetes treatment. Rev Diabet Stud RDS. 2011;8(3):348-54.
    • (2011) Rev Diabet Stud RDS , vol.8 , Issue.3 , pp. 348-354
    • Bhartia, M.1    Tahrani, A.A.2    Barnett, A.H.3
  • 43
    • 33746340623 scopus 로고    scopus 로고
    • Metformin improves endothelial vascular reactivity in first-degree relatives of type 2 diabetic patients with metabolic syndrome and normal glucose tolerance
    • DOI 10.2337/diacare.2951083
    • de Aguiar LG, Bahia LR, Villela N, Laflor C, Sicuro F, Wiernsperger N, et al. Metformin improves endothelial vascular reactivity in first-degree relatives of type 2 diabetic patients with metabolic syndrome and normal glucose tolerance. Diabetes Care. 2006;29(5):1083-9. (Pubitemid 44115248)
    • (2006) Diabetes Care , vol.29 , Issue.5 , pp. 1083-1089
    • Kraemer De Aguiar, L.G.1    Bahia, L.R.2    Villela, N.3    Laflor, C.4    Sicuro, F.5    Wiernsperger, N.6    Bottino, D.7    Bouskela, E.8
  • 47
    • 0842289940 scopus 로고    scopus 로고
    • In Type 2 Diabetes, Rosiglitazone Therapy for Insulin Resistance Ameliorates Endothelial Dysfunction Independent of Glucose Control
    • DOI 10.2337/diacare.27.2.484
    • Pistrosch F, Passauer J, Fischer S, Fuecker K, Hanefeld M, Gross P. In type 2 diabetes, rosiglitazone therapy for insulin resistance ameliorates endothelial dysfunction independent of glucose control. Diabetes Care. 2004;27(2):484-90. (Pubitemid 38174076)
    • (2004) Diabetes Care , vol.27 , Issue.2 , pp. 484-490
    • Pistrosch, F.1    Passauer, J.2    Fischer, S.3    Fuecker, K.4    Hanefeld, M.5    Gross, P.6
  • 48
    • 0034577620 scopus 로고    scopus 로고
    • Troglitazone improves endothelial dysfunction in patients with insulin resistance
    • 11480457 1:CAS:528:DC%2BD3MXktlelsb4%3D
    • Watanabe Y, Sunayama S, Shimada K, Sawano M, Hoshi S, Iwama Y, et al. Troglitazone improves endothelial dysfunction in patients with insulin resistance. J Atheroscler Thromb. 2000;7(3):159-63.
    • (2000) J Atheroscler Thromb , vol.7 , Issue.3 , pp. 159-163
    • Watanabe, Y.1    Sunayama, S.2    Shimada, K.3    Sawano, M.4    Hoshi, S.5    Iwama, Y.6
  • 50
    • 0842303207 scopus 로고    scopus 로고
    • Effects of Rosiglitazone on endothelial function, C-reactive protein, and components of the metabolic syndrome in nondiabetic patients with the metabolic syndrome
    • DOI 10.1016/j.amjcard.2003.10.022
    • Wang TD, Chen WJ, Lin JW, Chen MF, Lee YT. Effects of rosiglitazone on endothelial function, C-reactive protein, and components of the metabolic syndrome in nondiabetic patients with the metabolic syndrome. Am J Cardiol. 2004;93(3):362-5. (Pubitemid 38167440)
    • (2004) American Journal of Cardiology , vol.93 , Issue.3 , pp. 362-365
    • Wang, T.-D.1    Chen, W.-J.2    Lin, J.-W.3    Chen, M.-F.4    Lee, Y.-T.5
  • 51
    • 27744546647 scopus 로고    scopus 로고
    • Influence of glucose control and improvement of insulin resistance on microvascular blood flow and endothelial function in patients with diabetes mellitus type 2
    • DOI 10.1080/10739680500253402
    • Forst T, Lubben G, Hohberg C, Kann P, Sachara C, Gottschall V, et al. Influence of glucose control and improvement of insulin resistance on microvascular blood flow and endothelial function in patients with diabetes mellitus type 2. Microcirculation. 2005;12(7):543-50. (Pubitemid 41632173)
    • (2005) Microcirculation , vol.12 , Issue.7 , pp. 543-550
    • Forst, T.1    Lubben, G.2    Hohberg, C.3    Kann, P.4    Sachara, C.5    Gottschall, V.6    Friedrich, C.7    Rosskope, R.8    Pfuutzner, A.9
  • 52
    • 33644687456 scopus 로고    scopus 로고
    • Short-term pioglitazone treatment improves vascular function irrespective of metabolic changes in patients with type 2 diabetes
    • DOI 10.1097/01.fjc.0000187176.13403.05, PII 0000534420051200000009
    • Martens FM, Visseren FL, de Koning EJ, Rabelink TJ. Short-term pioglitazone treatment improves vascular function irrespective of metabolic changes in patients with type 2 diabetes. J Cardiovasc Pharmacol. 2005;46(6):773-8. (Pubitemid 44378249)
    • (2005) Journal of Cardiovascular Pharmacology , vol.46 , Issue.6 , pp. 773-778
    • Martens, F.M.A.C.1    Visseren, F.L.J.2    De Koning, E.J.P.3    Rabelink, T.J.4
  • 53
    • 69249215302 scopus 로고    scopus 로고
    • Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes
    • 19506330 1:CAS:528:DC%2BD1MXhsVert7jN 10.1507/endocrj.K08E-308
    • Tsuchiya K, Akaza I, Yoshimoto T, Hirata Y. Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes. Endocr J. 2009;56(5):691-8.
    • (2009) Endocr J , vol.56 , Issue.5 , pp. 691-698
    • Tsuchiya, K.1    Akaza, I.2    Yoshimoto, T.3    Hirata, Y.4
  • 56
    • 33845205804 scopus 로고    scopus 로고
    • Pioglitazone increases the numbers and improves the functional capacity of endothelial progenitor cells in patients with diabetes mellitus
    • DOI 10.1016/j.ahj.2006.07.029, PII S0002870306008106
    • Wang CH, Ting MK, Verma S, Kuo LT, Yang NI, Hsieh IC, et al. Pioglitazone increases the numbers and improves the functional capacity of endothelial progenitor cells in patients with diabetes mellitus. Am Hear J. 2006;152(6):e1051-8. 1051. (Pubitemid 44854808)
    • (2006) American Heart Journal , vol.152 , Issue.6
    • Wang, C.-H.1    Ting, M.-K.2    Verma, S.3    Kuo, L.-T.4    Yang, N.-I.5    Hsieh, I.-C.6    Wang, S.-Y.7    Hung, A.8    Cherng, W.-J.9
  • 57
    • 38449122045 scopus 로고    scopus 로고
    • Rosiglitazone improves endothelial function and inflammation but not asymmetric dimethylarginine or oxidative stress in patients with type 2 diabetes mellitus
    • 18048467 10.1177/1358863X07084200
    • Kelly AS, Thelen AM, Kaiser DR, Gonzalez-Campoy JM, Bank AJ. Rosiglitazone improves endothelial function and inflammation but not asymmetric dimethylarginine or oxidative stress in patients with type 2 diabetes mellitus. Vasc Med. 2007;12(4):311-8.
    • (2007) Vasc Med , vol.12 , Issue.4 , pp. 311-318
    • Kelly, A.S.1    Thelen, A.M.2    Kaiser, D.R.3    Gonzalez-Campoy, J.M.4    Bank, A.J.5
  • 59
    • 58149125347 scopus 로고    scopus 로고
    • Pioglitazone increases adiponectin levels in nondiabetic patients with coronary artery disease
    • 18580598
    • Patel SR, Mailloux LM, Coppola JT, Mindrescu C, Staniloae CS. Pioglitazone increases adiponectin levels in nondiabetic patients with coronary artery disease. Coron Artery Dis. 2008;19(5):349-53.
    • (2008) Coron Artery Dis , vol.19 , Issue.5 , pp. 349-353
    • Patel, S.R.1    Mailloux, L.M.2    Coppola, J.T.3    Mindrescu, C.4    Staniloae, C.S.5
  • 60
    • 0029977757 scopus 로고    scopus 로고
    • Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance
    • 8647954 1:CAS:528:DyaK28XjsFKjsLY%3D 10.1172/JCI118709
    • Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Investig. 1996;97(11):2601-10.
    • (1996) J Clin Investig , vol.97 , Issue.11 , pp. 2601-2610
    • Steinberg, H.O.1    Chaker, H.2    Leaming, R.3    Johnson, A.4    Brechtel, G.5    Baron, A.D.6
  • 63
    • 7044269441 scopus 로고    scopus 로고
    • Free fatty acid levels modulate microvascular function: Relevance for obesity-associated insulin resistance, hypertension, and microangiopathy
    • DOI 10.2337/diabetes.53.11.2873
    • de Jongh RT, Serne EH, Ijzerman RG, de Vries G, Stehouwer CD. Free fatty acid levels modulate microvascular function: relevance for obesity-associated insulin resistance, hypertension, and microangiopathy. Diabetes. 2004;53(11):2873-82. (Pubitemid 39425913)
    • (2004) Diabetes , vol.53 , Issue.11 , pp. 2873-2882
    • De Jongh, R.T.1    Serne, E.H.2    Ijzerman, R.G.3    De Vries, G.4    Stehouwer, C.D.A.5
  • 64
    • 0019370336 scopus 로고
    • Pharmacological profile of a new anti-lipolytic agent: 5-Methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) (1) I. Mechanism of action
    • DOI 10.1016/S0031-6989(81)80016-1
    • Lovisolo PP, Briatico-Vangosa G, Orsini G, Ronchi R, Angelucci R, Valzelli G. Pharmacological profile of a new anti-lipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) (1) I - Mechanism of action. Pharmacol Res Commun. 1981;13(2):151-61. (Pubitemid 11183346)
    • (1981) Pharmacological Research Communications , vol.13 , Issue.2 , pp. 151-161
    • Lovisolo, P.P.1    Briatico-Vangosa, G.2    Orsini, G.3
  • 66
    • 41149175907 scopus 로고    scopus 로고
    • Mechanism of action of niacin
    • 18375237 1:CAS:528:DC%2BD1cXlslWgsbs%3D 10.1016/j.amjcard.2008.02.029
    • Kamanna VS, Kashyap ML. Mechanism of action of niacin. Am J Cardiol. 2008;101(8A):20B-6B.
    • (2008) Am J Cardiol , vol.101 , Issue.8
    • Kamanna, V.S.1    Kashyap, M.L.2
  • 67
    • 81755165942 scopus 로고    scopus 로고
    • Nicotinic acid (niacin): New lipid-independent mechanisms of action and therapeutic potentials
    • 21944259 1:CAS:528:DC%2BC3MXhsV2mu7zM 10.1016/j.tips.2011.08.002
    • Lukasova M, Hanson J, Tunaru S, Offermanns S. Nicotinic acid (niacin): new lipid-independent mechanisms of action and therapeutic potentials. Trends Pharmacol Sci. 2011;32(12):700-7.
    • (2011) Trends Pharmacol Sci , vol.32 , Issue.12 , pp. 700-707
    • Lukasova, M.1    Hanson, J.2    Tunaru, S.3    Offermanns, S.4
  • 68
    • 0030612713 scopus 로고    scopus 로고
    • Effect of gemfibrozil ± niacin ± cholestyramine on endothelial function in patients with serum low-density lipoprotein cholesterol levels < 160 mg/dl and high-density lipoprotein cholesterol levels < 40 mg/dl
    • DOI 10.1016/S0002-9149(97)00531-6, PII S0002914997005316
    • Andrews TC, Whitney EJ, Green G, Kalenian R, Personius BE. Effect of gemfibrozil +/- niacin +/- cholestyramine on endothelial function in patients with serum low-density lipoprotein cholesterol levels <160 mg/dl and high-density lipoprotein cholesterol levels <40 mg/dl. Am J Cardiol. 1997;80(7):831-5. (Pubitemid 27459153)
    • (1997) American Journal of Cardiology , vol.80 , Issue.7 , pp. 831-835
    • Andrews, T.C.1    Whitney, E.J.2    Green, G.3    Kalenian, R.4    Personius, B.E.5
  • 69
    • 67349209273 scopus 로고    scopus 로고
    • Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: Results of the randomized, double-blind, placebo-controlled INEF study
    • 18822413 1:CAS:528:DC%2BD1MXlsVKgtb0%3D 10.1016/j.atherosclerosis.2008. 08.003
    • Warnholtz A, Wild P, Ostad MA, Elsner V, Stieber F, Schinzel R, et al. Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: results of the randomized, double-blind, placebo-controlled INEF study. Atherosclerosis. 2009;204(1):216-21.
    • (2009) Atherosclerosis , vol.204 , Issue.1 , pp. 216-221
    • Warnholtz, A.1    Wild, P.2    Ostad, M.A.3    Elsner, V.4    Stieber, F.5    Schinzel, R.6
  • 70
    • 0025677464 scopus 로고
    • Acute changes in plasma non-esterified fatty acid concentration do not change hepatic glucose production in people with type 2 diabetes
    • 1:STN:280:DyaK3M7ks1antA%3D%3D 10.1111/j.1464-5491.1990.tb01321.x
    • Johnston P, Hollenbeck C, Sheu W, Chen YD, Reaven GM. Acute changes in plasma non-esterified fatty acid concentration do not change hepatic glucose production in people with type 2 diabetes. Diabet Med J Br Diabet Assoc. 1990;7(10):871-5.
    • (1990) Diabet Med J Br Diabet Assoc , vol.7 , Issue.10 , pp. 871-875
    • Johnston, P.1    Hollenbeck, C.2    Sheu, W.3    Chen, Y.D.4    Reaven, G.M.5
  • 71
    • 0029805774 scopus 로고    scopus 로고
    • Impact of nicotinic acid treatment on insulin secretion and insulin sensitivity in low and high insulin responders
    • Alvarsson M, Grill V. Impact of nicotinic acid treatment on insulin secretion and insulin sensitivity in low and high insulin responders. Scand J Clin Lab Investig. 1996;56(6):563-70. (Pubitemid 26342641)
    • (1996) Scandinavian Journal of Clinical and Laboratory Investigation , vol.56 , Issue.6 , pp. 563-570
    • Alvarsson, M.1    Grill, V.2
  • 72
    • 0033812857 scopus 로고    scopus 로고
    • Effects of nicotinic acid on insulin sensitivity and blood pressure in healthy subjects
    • 10980588 1:STN:280:DC%2BD3cvps1ygsQ%3D%3D 10.1038/sj.jhh.1001099
    • Kelly JJ, Lawson JA, Campbell LV, Storlien LH, Jenkins AB, Whitworth JA, et al. Effects of nicotinic acid on insulin sensitivity and blood pressure in healthy subjects. J Hum Hypertens. 2000;14(9):567-72.
    • (2000) J Hum Hypertens , vol.14 , Issue.9 , pp. 567-572
    • Kelly, J.J.1    Lawson, J.A.2    Campbell, L.V.3    Storlien, L.H.4    Jenkins, A.B.5    Whitworth, J.A.6
  • 73
    • 84859158042 scopus 로고    scopus 로고
    • Fish oil - How does it reduce plasma triglycerides?
    • 22041134 1:CAS:528:DC%2BC38Xkslaru7g%3D 10.1016/j.bbalip.2011.10.011
    • Shearer GC, Savinova OV, Harris WS. Fish oil - how does it reduce plasma triglycerides? Biochim Biophys Acta. 2012;1821(5):843-51.
    • (2012) Biochim Biophys Acta , vol.1821 , Issue.5 , pp. 843-851
    • Shearer, G.C.1    Savinova, O.V.2    Harris, W.S.3
  • 74
    • 0029964924 scopus 로고    scopus 로고
    • Long-term effects of fish oil on insulin resistance and plasma lipoproteins in NIDDM patients with hypertriglyceridemia
    • 8908381 1:STN:280:DyaK2s%2FmsVygsw%3D%3D 10.2337/diacare.19.11.1207
    • Rivellese AA, Maffettone A, Iovine C, Di Marino L, Annuzzi G, Mancini M, et al. Long-term effects of fish oil on insulin resistance and plasma lipoproteins in NIDDM patients with hypertriglyceridemia. Diabetes Care. 1996;19(11):1207-13.
    • (1996) Diabetes Care , vol.19 , Issue.11 , pp. 1207-1213
    • Rivellese, A.A.1    Maffettone, A.2    Iovine, C.3    Di Marino, L.4    Annuzzi, G.5    Mancini, M.6
  • 75
    • 0242661906 scopus 로고    scopus 로고
    • A Fish Oil Diet Does Not Reverse Insulin Resistance despite Decreased Adipose Tissue TNF-α Protein Concentration in ApoE-3*Leiden Mice
    • Muurling M, Mensink RP, Pijl H, Romijn JA, Havekes LM, Voshol PJ. A fish oil diet does not reverse insulin resistance despite decreased adipose tissue TNF-alpha protein concentration in ApoE-3*Leiden mice. J Nutr. 2003;133(11):3350-5. (Pubitemid 37409458)
    • (2003) Journal of Nutrition , vol.133 , Issue.11 , pp. 3350-3355
    • Muurling, M.1    Mensink, R.P.2    Pijl, H.3    Romijn, J.A.4    Havekes, L.M.5    Voshol, P.J.6
  • 76
    • 0027448328 scopus 로고
    • Dietary fish oil augments nitric oxide production or release in patients with Type 2 (non-insulin-dependent) diabetes mellitus
    • DOI 10.1007/BF00399090
    • McVeigh GE, Brennan GM, Johnston GD, McDermott BJ, McGrath LT, Henry WR, et al. Dietary fish oil augments nitric oxide production or release in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia. 1993;36(1):33-8. (Pubitemid 23018332)
    • (1993) Diabetologia , vol.36 , Issue.1 , pp. 33-38
    • McVeigh, G.E.1    Brennan, G.M.2    Johnston, G.D.3    McDermott, B.J.4    McGrath, L.T.5    Henry, W.R.6    Andrews, J.W.7    Hayes, J.R.8
  • 77
    • 0034641662 scopus 로고    scopus 로고
    • Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight men
    • 10982541 1:CAS:528:DC%2BD3cXntFCgt78%3D 10.1161/01.CIR.102.11.1264
    • Mori TA, Watts GF, Burke V, Hilme E, Puddey IB, Beilin LJ. Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight men. Circulation. 2000;102(11):1264-9.
    • (2000) Circulation , vol.102 , Issue.11 , pp. 1264-1269
    • Mori, T.A.1    Watts, G.F.2    Burke, V.3    Hilme, E.4    Puddey, I.B.5    Beilin, L.J.6
  • 78
    • 70349410386 scopus 로고    scopus 로고
    • Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes
    • 19394939 1:CAS:528:DC%2BD1MXht1aju7bJ 10.1016/j.atherosclerosis.2009.03. 006
    • Rizza S, Tesauro M, Cardillo C, Galli A, Iantorno M, Gigli F, et al. Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes. Atherosclerosis. 2009;206(2):569-74.
    • (2009) Atherosclerosis , vol.206 , Issue.2 , pp. 569-574
    • Rizza, S.1    Tesauro, M.2    Cardillo, C.3    Galli, A.4    Iantorno, M.5    Gigli, F.6
  • 79
    • 17544403857 scopus 로고    scopus 로고
    • Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group II: Pathogenesis of atherosclerosis in diabetes
    • 11994264 10.1161/01.CIR.0000013954.65303.C5
    • Eckel RH, Wassef M, Chait A, Sobel B, Barrett E, King G, et al. Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group II: pathogenesis of atherosclerosis in diabetes. Circulation. 2002;105(18):e138-43.
    • (2002) Circulation , vol.105 , Issue.18
    • Eckel, R.H.1    Wassef, M.2    Chait, A.3    Sobel, B.4    Barrett, E.5    King, G.6
  • 80
    • 33745324596 scopus 로고    scopus 로고
    • Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes
    • DOI 10.2337/diabetes.55.04.06.db05-1076
    • Natali A, Toschi E, Baldeweg S, Ciociaro D, Favilla S, Sacca L, et al. Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes. Diabetes. 2006;55(4):1133-40. (Pubitemid 44100192)
    • (2006) Diabetes , vol.55 , Issue.4 , pp. 1133-1140
    • Natali, A.1    Toschi, E.2    Baldeweg, S.3    Ciociaro, D.4    Favilla, S.5    Sacca, L.6    Ferrannini, E.7
  • 81
    • 33744917283 scopus 로고    scopus 로고
    • Increased levels of tumour necrosis factor-α (TNF-α) in patients with Type II diabetes mellitus after myocardial infarction are related to endothelial dysfunction
    • DOI 10.1042/CS20050353
    • Nystrom T, Nygren A, Sjoholm A. Increased levels of tumour necrosis factor-alpha (TNF-alpha) in patients with Type II diabetes mellitus after myocardial infarction are related to endothelial dysfunction. Clin Sci. 2006;110(6):673-81. (Pubitemid 43844737)
    • (2006) Clinical Science , vol.110 , Issue.6 , pp. 673-681
    • Nystrom, T.1    Nygren, A.2    Sjoholm, A.3
  • 82
    • 41949130341 scopus 로고    scopus 로고
    • Association of high sensitivity C-reactive protein (hsCRP) and tumour necrosis factor-alpha (TNF-alpha) with carotid intimal medial thickness in subjects with different grades of glucose intolerance-the Chennai Urban Rural Epidemiology Study (CURES-31)
    • 18328265 1:CAS:528:DC%2BD1cXks12it7g%3D 10.1016/j.clinbiochem.2008.01.030
    • Gokulakrishnan K, Deepa R, Mohan V. Association of high sensitivity C-reactive protein (hsCRP) and tumour necrosis factor-alpha (TNF-alpha) with carotid intimal medial thickness in subjects with different grades of glucose intolerance-the Chennai Urban Rural Epidemiology Study (CURES-31). Clin Biochem. 2008;41(7-8):480-5.
    • (2008) Clin Biochem , vol.41 , Issue.7-8 , pp. 480-485
    • Gokulakrishnan, K.1    Deepa, R.2    Mohan, V.3
  • 83
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259(5091):87-91. (Pubitemid 23036092)
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 84
    • 0028587742 scopus 로고
    • Tumor necrosis factor alpha: A key component of the obesity-diabetes link
    • 7926300 1:CAS:528:DyaK2cXmslOltro%3D 10.2337/diabetes.43.11.1271
    • Hotamisligil GS, Spiegelman BM. Tumor necrosis factor alpha: a key component of the obesity-diabetes link. Diabetes. 1994;43(11):1271-8.
    • (1994) Diabetes , vol.43 , Issue.11 , pp. 1271-1278
    • Hotamisligil, G.S.1    Spiegelman, B.M.2
  • 86
    • 0142053963 scopus 로고    scopus 로고
    • Tumor Necrosis Factor-α Inhibits Insulin's Stimulating Effect on Glucose Uptake and Endothelium-Dependent Vasodilation in Humans
    • DOI 10.1161/01.CIR.0000091406.72832.11
    • Rask-Madsen C, Dominguez H, Ihlemann N, Hermann T, Kober L, Torp-Pedersen C. Tumor necrosis factor-alpha inhibits insulin's stimulating effect on glucose uptake and endothelium-dependent vasodilation in humans. Circulation. 2003;108(15):1815-21. (Pubitemid 37296090)
    • (2003) Circulation , vol.108 , Issue.15 , pp. 1815-1821
    • Rask-Madsen, C.1    Dominguez, H.2    Ihlemann, N.3    Hermann, T.4    Kober, L.5    Torp-Pedersen, C.6
  • 88
    • 77955277483 scopus 로고    scopus 로고
    • Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth
    • 19926177 1:CAS:528:DC%2BC3cXpsFOqsbw%3D 10.1016/j.clnu.2009.10.008
    • Harvey KA, Walker CL, Pavlina TM, Xu Z, Zaloga GP, Siddiqui RA. Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth. Clin Nutr. 2010;29(4):492-500.
    • (2010) Clin Nutr , vol.29 , Issue.4 , pp. 492-500
    • Harvey, K.A.1    Walker, C.L.2    Pavlina, T.M.3    Xu, Z.4    Zaloga, G.P.5    Siddiqui, R.A.6
  • 89
    • 34248354782 scopus 로고    scopus 로고
    • Postprandial endothelial dysfunction: Role of glucose, lipids and insulin
    • Nitenberg A, Cosson E, Pham I. Postprandial endothelial dysfunction: role of glucose, lipids and insulin. Diabete Metab. 2006;32(Spec No2):2S28-33. (Pubitemid 47216113)
    • (2006) Diabetes and Metabolism , vol.32 , Issue.2
    • Nitenberg, A.1    Cosson, E.2    Pham, I.3
  • 90
    • 0035753437 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products, inflammation, and accelerated periodontal disease in diabetes: Mechanisms and insights into therapeutic modalities
    • 1:STN:280:DC%2BD387lsFKktw%3D%3D 10.1902/annals.2001.6.1.113
    • Lalla E, Lamster IB, Stern DM, Schmidt AM. Receptor for advanced glycation end products, inflammation, and accelerated periodontal disease in diabetes: mechanisms and insights into therapeutic modalities. Ann Periodontol Am Acad Periodontol. 2001;6(1):113-8.
    • (2001) Ann Periodontol Am Acad Periodontol , vol.6 , Issue.1 , pp. 113-118
    • Lalla, E.1    Lamster, I.B.2    Stern, D.M.3    Schmidt, A.M.4
  • 93
    • 62349142022 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor alpha inhibition with infliximab on lipid levels and insulin resistance in patients with inflammatory bowel disease
    • 19279474 1:CAS:528:DC%2BD1MXivFeqtrk%3D 10.1097/MEG.0b013e328325d42b
    • Koutroubakis IE, Oustamanolakis P, Malliaraki N, Karmiris K, Chalkiadakis I, Ganotakis E, et al. Effects of tumor necrosis factor alpha inhibition with infliximab on lipid levels and insulin resistance in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2009;21(3):283-8.
    • (2009) Eur J Gastroenterol Hepatol , vol.21 , Issue.3 , pp. 283-288
    • Koutroubakis, I.E.1    Oustamanolakis, P.2    Malliaraki, N.3    Karmiris, K.4    Chalkiadakis, I.5    Ganotakis, E.6
  • 95
    • 78650917112 scopus 로고    scopus 로고
    • TNF-alpha antagonism with etanercept decreases glucose and increases the proportion of high molecular weight adiponectin in obese subjects with features of the metabolic syndrome
    • 21047923 1:CAS:528:DC%2BC3MXhtFGmsLs%3D 10.1210/jc.2010-1170
    • Stanley TL, Zanni MV, Johnsen S, Rasheed S, Makimura H, Lee H, et al. TNF-alpha antagonism with etanercept decreases glucose and increases the proportion of high molecular weight adiponectin in obese subjects with features of the metabolic syndrome. J Clin Endocrinol Metab. 2011;96(1):E146-50.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.1
    • Stanley, T.L.1    Zanni, M.V.2    Johnsen, S.3    Rasheed, S.4    Makimura, H.5    Lee, H.6
  • 97
    • 3042725473 scopus 로고    scopus 로고
    • Lowered tumor necrosis factor receptors, but not increased insulin sensitivity, with infliximab
    • Di Rocco P, Manco M, Rosa G, Greco AV, Mingrone G. Lowered tumor necrosis factor receptors, but not increased insulin sensitivity, with infliximab. Obes Res. 2004;12(4):734-9. (Pubitemid 41132519)
    • (2004) Obesity Research , vol.12 , Issue.4 , pp. 734-739
    • Di Rocco, P.1    Manco, M.2    Rosa, G.3    Greco, A.V.4    Mingrone, G.5
  • 99
    • 35148818401 scopus 로고    scopus 로고
    • Effect of etanercept on insulin secretion and insulin sensitivity in a randomized trial with psoriatic patients at risk for developing type 2 diabetes mellitus
    • DOI 10.1007/s00403-007-0784-3
    • Martinez-Abundis E, Reynoso-von Drateln C, Hernandez-Salazar E, Gonzalez-Ortiz M. Effect of etanercept on insulin secretion and insulin sensitivity in a randomized trial with psoriatic patients at risk for developing type 2 diabetes mellitus. Arch Dermatol Res. 2007;299(9):461-5. (Pubitemid 47546924)
    • (2007) Archives of Dermatological Research , vol.299 , Issue.9 , pp. 461-465
    • Martinez-Abundis, E.1    Reynoso-Von Drateln, C.2    Hernandez-Salazar, E.3    Gonzalez-Ortiz, M.4
  • 101
    • 2642571902 scopus 로고    scopus 로고
    • Active but transient improvement of endothelial function in rheumatoid arthritis patients undergoing long-term treatment with anti-tumor necrosis factor α antibody
    • Gonzalez-Juanatey C, Testa A, Garcia-Castelo A, Garcia-Porrua C, Llorca J, Gonzalez-Gay MA. Active but transient improvement of endothelial function in rheumatoid arthritis patients undergoing long-term treatment with anti-tumor necrosis factor alpha antibody. Arthritis Rheum. 2004;51(3):447-50. (Pubitemid 38725146)
    • (2004) Arthritis Care and Research , vol.51 , Issue.3 , pp. 447-450
    • Gonzalez-Juanatey, C.1    Testa, A.2    Garcia-Castelo, A.3    Garcia-Porrua, C.4    Llorca, J.5    Gonzalez-Gay, M.A.6
  • 103
    • 45049086778 scopus 로고    scopus 로고
    • TNF-alpha blockade induces a reversible but transient effect on endothelial dysfunction in patients with long-standing severe rheumatoid arthritis
    • 18075712 10.1007/s10067-007-0803-y
    • Bosello S, Santoliquido A, Zoli A, Di Campli C, Flore R, Tondi P, et al. TNF-alpha blockade induces a reversible but transient effect on endothelial dysfunction in patients with long-standing severe rheumatoid arthritis. Clin Rheumatol. 2008;27(7):833-9.
    • (2008) Clin Rheumatol , vol.27 , Issue.7 , pp. 833-839
    • Bosello, S.1    Santoliquido, A.2    Zoli, A.3    Di Campli, C.4    Flore, R.5    Tondi, P.6
  • 104
    • 37549028415 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha antagonism improves endothelial dysfunction in patients with Crohn's disease
    • 17507924 1:CAS:528:DC%2BD2sXhsVylt7fN 10.1038/sj.clpt.6100229
    • Schinzari F, Armuzzi A, De Pascalis B, Mores N, Tesauro M, Melina D, et al. Tumor necrosis factor-alpha antagonism improves endothelial dysfunction in patients with Crohn's disease. Clin Pharmacol Ther. 2008;83(1):70-6.
    • (2008) Clin Pharmacol Ther , vol.83 , Issue.1 , pp. 70-76
    • Schinzari, F.1    Armuzzi, A.2    De Pascalis, B.3    Mores, N.4    Tesauro, M.5    Melina, D.6
  • 105
    • 79952856377 scopus 로고    scopus 로고
    • Chronic TNF-alpha neutralization does not improve insulin resistance or endothelial function in "healthy" men with metabolic syndrome
    • 21103669 1:CAS:528:DC%2BC3MXjvFWgtLw%3D
    • Wascher TC, Lindeman JH, Sourij H, Kooistra T, Pacini G, Roden M. Chronic TNF-alpha neutralization does not improve insulin resistance or endothelial function in "healthy" men with metabolic syndrome. Mol Med. 2011;17(3-4):189-93.
    • (2011) Mol Med , vol.17 , Issue.3-4 , pp. 189-193
    • Wascher, T.C.1    Lindeman, J.H.2    Sourij, H.3    Kooistra, T.4    Pacini, G.5    Roden, M.6
  • 106
    • 33745861300 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • 16823477 1:CAS:528:DC%2BD28XmvV2ltLo%3D 10.1172/JCI29069
    • Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Investig. 2006;116(7):1793-801.
    • (2006) J Clin Investig , vol.116 , Issue.7 , pp. 1793-1801
    • Shoelson, S.E.1    Lee, J.2    Goldfine, A.B.3
  • 107
    • 38949119419 scopus 로고    scopus 로고
    • Salsalate improves glycemia and inflammatory parameters in obese young adults
    • DOI 10.2337/dc07-1338
    • Fleischman A, Shoelson SE, Bernier R, Goldfine AB. Salsalate improves glycemia and inflammatory parameters in obese young adults. Diabetes Care. 2008;31(2):289-94. (Pubitemid 351213338)
    • (2008) Diabetes Care , vol.31 , Issue.2 , pp. 289-294
    • Fleischman, A.1    Shoelson, S.E.2    Bernier, R.3    Goldfine, A.B.4
  • 108
    • 64149121817 scopus 로고    scopus 로고
    • Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes
    • 19337387 1:CAS:528:DC%2BD1cXpt1Gnsbo%3D 10.1111/j.1752-8062.2008.00026.x
    • Goldfine AB, Silver R, Aldhahi W, Cai D, Tatro E, Lee J, et al. Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes. Clin Transl Sci. 2008;1(1):36-43.
    • (2008) Clin Transl Sci , vol.1 , Issue.1 , pp. 36-43
    • Goldfine, A.B.1    Silver, R.2    Aldhahi, W.3    Cai, D.4    Tatro, E.5    Lee, J.6
  • 109
    • 77950885686 scopus 로고    scopus 로고
    • The effects of salsalate on glycemic control in patients with type 2 diabetes: A randomized trial
    • 20231565
    • Goldfine AB, Fonseca V, Jablonski KA, Pyle L, Staten MA, Shoelson SE. The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial. Ann Intern Med. 2010;152(6):346-57.
    • (2010) Ann Intern Med , vol.152 , Issue.6 , pp. 346-357
    • Goldfine, A.B.1    Fonseca, V.2    Jablonski, K.A.3    Pyle, L.4    Staten, M.A.5    Shoelson, S.E.6
  • 110
    • 43149087317 scopus 로고    scopus 로고
    • Improvement in HIV-related endothelial dysfunction using the anti-inflammatory agent salsalate: A pilot study
    • DOI 10.1097/QAD.0b013e3282f470d2, PII 0000203020080312000014
    • Gupta SK, Johnson RM, Saha C, Mather KJ, Greenwald ML, Waltz JS, et al. Improvement in HIV-related endothelial dysfunction using the anti-inflammatory agent salsalate: a pilot study. AIDS. 2008;22(5):653-5. (Pubitemid 351640600)
    • (2008) AIDS , vol.22 , Issue.5 , pp. 653-655
    • Gupta, S.K.1    Johnson, R.M.2    Saha, C.3    Mather, K.J.4    Greenwald, M.L.5    Waltz, J.S.6    Rehman, J.7    Dube, M.P.8
  • 111
    • 63649097932 scopus 로고    scopus 로고
    • Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans
    • 19237660 1:CAS:528:DC%2BD1MXisFCjsLY%3D 10.1161/CIRCULATIONAHA.108.804294
    • Pierce GL, Lesniewski LA, Lawson BR, Beske SD, Seals DR. Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans. Circulation. 2009;119(9):1284-92.
    • (2009) Circulation , vol.119 , Issue.9 , pp. 1284-1292
    • Pierce, G.L.1    Lesniewski, L.A.2    Lawson, B.R.3    Beske, S.D.4    Seals, D.R.5
  • 112
    • 0034695098 scopus 로고    scopus 로고
    • The biology of the receptor for advanced glycation end products and its ligands
    • 11108954 1:CAS:528:DC%2BD3cXosFCjsrw%3D 10.1016/S0167-4889(00)00087-2
    • Schmidt AM, Yan SD, Yan SF, Stern DM. The biology of the receptor for advanced glycation end products and its ligands. Biochim Biophys Acta. 2000;1498(2-3):99-111.
    • (2000) Biochim Biophys Acta , vol.1498 , Issue.2-3 , pp. 99-111
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3    Stern, D.M.4
  • 113
    • 4344600477 scopus 로고    scopus 로고
    • Effect of advanced glycation end-products on gene expression and synthesis of TNF-α and endothelial nitric oxide synthase by endothelial cells
    • DOI 10.1111/j.1523-1755.2004.00860.x
    • Rashid G, Benchetrit S, Fishman D, Bernheim J. Effect of advanced glycation end-products on gene expression and synthesis of TNF-alpha and endothelial nitric oxide synthase by endothelial cells. Kidney Int. 2004;66(3):1099-106. (Pubitemid 39121015)
    • (2004) Kidney International , vol.66 , Issue.3 , pp. 1099-1106
    • Rashid, G.1    Benchetrit, S.2    Fishman, D.3    Bernheim, J.4
  • 114
    • 77956819409 scopus 로고    scopus 로고
    • Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase
    • 20186099 1:CAS:528:DC%2BC3cXlt1KjtLs%3D 10.1097/HJH.0b013e328335043e
    • Soro-Paavonen A, Zhang WZ, Venardos K, Coughlan MT, Harris E, Tong DC, et al. Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase. J Hypertens. 2010;28(4):780-8.
    • (2010) J Hypertens , vol.28 , Issue.4 , pp. 780-788
    • Soro-Paavonen, A.1    Zhang, W.Z.2    Venardos, K.3    Coughlan, M.T.4    Harris, E.5    Tong, D.C.6
  • 115
    • 83455230038 scopus 로고    scopus 로고
    • Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes
    • 21788633 10.2337/dc10-2421 1:CAS:528:DC%2BC3MXht1OgsLfF
    • van Poppel PC, Netea MG, Smits P, Tack CJ. Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes. Diabetes Care. 2011;34(9):2072-7.
    • (2011) Diabetes Care , vol.34 , Issue.9 , pp. 2072-2077
    • Van Poppel, P.C.1    Netea, M.G.2    Smits, P.3    Tack, C.J.4
  • 116
    • 34547884217 scopus 로고    scopus 로고
    • Telmisartan, an angiotensin II type 1 receptor blocker, inhibits advanced glycation end-product (AGE)-induced monocyte chemoattractant protein-1 expression in mesangial cells through downregulation of receptor for AGEs via peroxisome proliferator-activated receptor-γ, activation
    • Matsui T, Yamagishi S, Ueda S, Nakamura K, Imaizumi T, Takeuchi M, et al. Telmisartan, an angiotensin II type 1 receptor blocker, inhibits advanced glycation end-product (AGE)-induced monocyte chemoattractant protein-1 expression in mesangial cells through downregulation of receptor for AGEs via peroxisome proliferator-activated receptor-gamma activation. J Int Med Res. 2007;35(4):482-9. (Pubitemid 47261110)
    • (2007) Journal of International Medical Research , vol.35 , Issue.4 , pp. 482-489
    • Matsui, T.1    Yamagishi, S.2    Ueda, S.3    Nakamura, K.4    Imaizumi, T.5    Takeuchi, M.6    Inoue, H.7
  • 117
    • 84861856434 scopus 로고    scopus 로고
    • The AGE-breaker ALT-711 restores high blood flow-dependent remodeling in mesenteric resistance arteries in a rat model of type 2 diabetes
    • 22415880 1:CAS:528:DC%2BC38XotlGqu7g%3D 10.2337/db11-0750
    • Freidja ML, Tarhouni K, Toutain B, Fassot C, Loufrani L, Henrion D. The AGE-breaker ALT-711 restores high blood flow-dependent remodeling in mesenteric resistance arteries in a rat model of type 2 diabetes. Diabetes. 2012;61(6):1562-72.
    • (2012) Diabetes , vol.61 , Issue.6 , pp. 1562-1572
    • Freidja, M.L.1    Tarhouni, K.2    Toutain, B.3    Fassot, C.4    Loufrani, L.5    Henrion, D.6
  • 118
    • 84866470030 scopus 로고    scopus 로고
    • Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling
    • 22934044 10.3389/fphys.2012.00292
    • Kranstuber AL, Del Rio C, Biesiadecki BJ, Hamlin RL, Ottobre J, Gyorke S, et al. Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling. Front Physiol. 2012;3:292.
    • (2012) Front Physiol , vol.3 , pp. 292
    • Kranstuber, A.L.1    Del Rio, C.2    Biesiadecki, B.J.3    Hamlin, R.L.4    Ottobre, J.5    Gyorke, S.6
  • 119
    • 79961098801 scopus 로고    scopus 로고
    • Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure
    • 1:CAS:528:DC%2BC3MXps1Ohsbs%3D 10.1093/eurjhf/hfr067
    • Hartog JW, Willemsen S, van Veldhuisen DJ, Posma JL, van Wijk LM, Hummel YM, et al. Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure. Eur J Hear Fail. 2011;13(8):899-908.
    • (2011) Eur J Hear Fail , vol.13 , Issue.8 , pp. 899-908
    • Hartog, J.W.1    Willemsen, S.2    Van Veldhuisen, D.J.3    Posma, J.L.4    Van Wijk, L.M.5    Hummel, Y.M.6
  • 120
    • 33846849277 scopus 로고    scopus 로고
    • Advanced glycation endproduct crosslink breaker (alagebrium) improves endothelial function in patients with isolated systolic hypertension
    • DOI 10.1097/HJH.0b013e328013e7dd, PII 0000487220070300000015
    • Zieman SJ, Melenovsky V, Clattenburg L, Corretti MC, Capriotti A, Gerstenblith G, et al. Advanced glycation endproduct crosslink breaker (alagebrium) improves endothelial function in patients with isolated systolic hypertension. J Hypertens. 2007;25(3):577-83. (Pubitemid 46213796)
    • (2007) Journal of Hypertension , vol.25 , Issue.3 , pp. 577-583
    • Zieman, S.J.1    Melenovsky, V.2    Clattenburg, L.3    Corretti, M.C.4    Capriotti, A.5    Gerstenblith, G.6    Kass, D.A.7
  • 123
    • 0002809563 scopus 로고    scopus 로고
    • The association between insulin resistance and endotheliopathy
    • 11220284 10.1046/j.1463-1326.1999.0010s1017.x
    • Tooke J. The association between insulin resistance and endotheliopathy. Diabetes Obes Metab. 1999;1 Suppl 1:S17-22.
    • (1999) Diabetes Obes Metab , vol.1 , Issue.SUPPL. 1
    • Tooke, J.1
  • 124
    • 0034135992 scopus 로고    scopus 로고
    • Antihypertensive drugs and reversing of endothelial dysfunction in hypertension
    • 10981130 1:STN:280:DC%2BD3M%2FhsFagsA%3D%3D 10.1007/s11906-000-0061-8
    • Taddei S, Virdis A, Ghiadoni L, Sudano I, Salvetti A. Antihypertensive drugs and reversing of endothelial dysfunction in hypertension. Curr Hypertens Rep. 2000;2(1):64-70.
    • (2000) Curr Hypertens Rep , vol.2 , Issue.1 , pp. 64-70
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Sudano, I.4    Salvetti, A.5
  • 127
    • 33947140280 scopus 로고    scopus 로고
    • Discrepancy between improvement of insulin sensitivity and that of arterial endothelial function in patients receiving antihypertensive medication
    • DOI 10.1097/HJH.0b013e3280149518, PII 0000487220070400000022
    • Tomiyama H, Yambe M, Yamada J, Motobe K, Koji Y, Yoshida M, et al. Discrepancy between improvement of insulin sensitivity and that of arterial endothelial function in patients receiving antihypertensive medication. J Hypertens. 2007;25(4):883-9. (Pubitemid 46398885)
    • (2007) Journal of Hypertension , vol.25 , Issue.4 , pp. 883-889
    • Tomiyama, H.1    Yambe, M.2    Yamada, J.3    Motobe, K.4    Koji, Y.5    Yoshida, M.6    Shiina, K.7    Yamashina, A.8
  • 128
    • 84872597203 scopus 로고    scopus 로고
    • Direct renin inhibitor prevents and ameliorates insulin resistance, aortic endothelial dysfunction and vascular remodeling in fructose-fed hypertensive rats
    • doi: 10.1038/hr.2012.124
    • Chou CL, Pang CY, Lee TJ, Fang TC. Direct renin inhibitor prevents and ameliorates insulin resistance, aortic endothelial dysfunction and vascular remodeling in fructose-fed hypertensive rats. Hypertens Res Off J Jpn Soc Hypertens. 2012. doi: 10.1038/hr.2012.124.
    • (2012) Hypertens Res off J Jpn Soc Hypertens
    • Chou, C.L.1    Pang, C.Y.2    Lee, T.J.3    Fang, T.C.4
  • 129
    • 84857030484 scopus 로고    scopus 로고
    • Effects of losartan on whole body, skeletal muscle and vascular insulin responses in obesity/insulin resistance without hypertension
    • 22051059 1:CAS:528:DC%2BC38XltFKksrg%3D 10.1111/j.1463-1326.2011.01522.x
    • Lteif AA, Chisholm RL, Gilbert K, Considine RV, Mather KJ. Effects of losartan on whole body, skeletal muscle and vascular insulin responses in obesity/insulin resistance without hypertension. Diabetes Obes Metab. 2012;14(3):254-61.
    • (2012) Diabetes Obes Metab , vol.14 , Issue.3 , pp. 254-261
    • Lteif, A.A.1    Chisholm, R.L.2    Gilbert, K.3    Considine, R.V.4    Mather, K.J.5
  • 131
    • 38049033935 scopus 로고    scopus 로고
    • Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: A meta-analysis
    • 18191683 1:CAS:528:DC%2BD1cXlt1Wquw%3D%3D 10.1016/S0140-6736(08)60104-X
    • Kearney PM, Blackwell L, Collins R, Keech A, Simes J, Peto R, et al. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet. 2008;371(9607):117-25.
    • (2008) Lancet , vol.371 , Issue.9607 , pp. 117-125
    • Kearney, P.M.1    Blackwell, L.2    Collins, R.3    Keech, A.4    Simes, J.5    Peto, R.6
  • 134
    • 48649083592 scopus 로고    scopus 로고
    • Simvastatin improves flow-mediated dilation but reduces adiponectin levels and insulin sensitivity in hypercholesterolemic patients
    • 18184901 1:CAS:528:DC%2BD1cXltVKhtbY%3D 10.2337/dc07-2199
    • Koh KK, Quon MJ, Han SH, Lee Y, Ahn JY, Kim SJ, et al. Simvastatin improves flow-mediated dilation but reduces adiponectin levels and insulin sensitivity in hypercholesterolemic patients. Diabetes Care. 2008;31(4):776-82.
    • (2008) Diabetes Care , vol.31 , Issue.4 , pp. 776-782
    • Koh, K.K.1    Quon, M.J.2    Han, S.H.3    Lee, Y.4    Ahn, J.Y.5    Kim, S.J.6
  • 135
    • 77952292502 scopus 로고    scopus 로고
    • Improved endothelial function with simvastatin but unchanged insulin sensitivity with simvastatin or ezetimibe
    • 20199786 10.1016/j.metabol.2010.02.011 1:CAS:528:DC%2BC3cXmsVehtr0%3D
    • Kater AL, Batista MC, Ferreira SR. Improved endothelial function with simvastatin but unchanged insulin sensitivity with simvastatin or ezetimibe. Metab Clin Exp. 2010;59(6):921-6.
    • (2010) Metab Clin Exp , vol.59 , Issue.6 , pp. 921-926
    • Kater, A.L.1    Batista, M.C.2    Ferreira, S.R.3
  • 136
    • 84863630296 scopus 로고    scopus 로고
    • Effect of pravastatin on endothelial function and endothelial progenitor cells in healthy postmenopausal women
    • 22905454 1:STN:280:DC%2BC38fpt1ahsw%3D%3D
    • Paradisi G, Bracaglia M, Basile F, Di'Ipolito S, Di Nicuolo F, Ianniello F, et al. Effect of pravastatin on endothelial function and endothelial progenitor cells in healthy postmenopausal women. Clin Exp Obstet Gynecol. 2012;39(2):153-9.
    • (2012) Clin Exp Obstet Gynecol , vol.39 , Issue.2 , pp. 153-159
    • Paradisi, G.1    Bracaglia, M.2    Basile, F.3    Di'Ipolito, S.4    Di Nicuolo, F.5    Ianniello, F.6
  • 137
    • 84862908066 scopus 로고    scopus 로고
    • Statin use and risk of diabetes mellitus in postmenopausal women in the Women's Health Initiative
    • 22231607 10.1001/archinternmed.2011.625
    • Culver AL, Ockene IS, Balasubramanian R, Olendzki BC, Sepavich DM, Wactawski-Wende J, et al. Statin use and risk of diabetes mellitus in postmenopausal women in the Women's Health Initiative. Arch Intern Med. 2012;172(2):144-52.
    • (2012) Arch Intern Med , vol.172 , Issue.2 , pp. 144-152
    • Culver, A.L.1    Ockene, I.S.2    Balasubramanian, R.3    Olendzki, B.C.4    Sepavich, D.M.5    Wactawski-Wende, J.6
  • 138
    • 84864861863 scopus 로고    scopus 로고
    • Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: An analysis from the JUPITER trial
    • 22883507 1:CAS:528:DC%2BC38XhtF2hs7%2FI 10.1016/S0140-6736(12)61190-8
    • Ridker PM, Pradhan A, MacFadyen JG, Libby P, Glynn RJ. Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial. Lancet. 2012;380(9841):565-71.
    • (2012) Lancet , vol.380 , Issue.9841 , pp. 565-571
    • Ridker, P.M.1    Pradhan, A.2    Macfadyen, J.G.3    Libby, P.4    Glynn, R.J.5
  • 139
    • 84871921229 scopus 로고    scopus 로고
    • Cardiovascular event reduction versus new-onset diabetes during atorvastatin therapy: Effect of baseline risk factors for diabetes
    • Waters DD, Ho JE, Boekholdt SM, Demicco DA, Kastelein JJ, Messig M, et al. Cardiovascular event reduction versus new-onset diabetes during atorvastatin therapy: effect of baseline risk factors for diabetes. J Am Coll Cardiol. 2012;61(2):148-52.
    • (2012) J Am Coll Cardiol. , vol.61 , Issue.2 , pp. 148-52
    • Waters, D.D.1    Ho, J.E.2    Boekholdt, S.M.3    Demicco, D.A.4    Kastelein, J.J.5    Messig, M.6
  • 140
    • 84875065352 scopus 로고    scopus 로고
    • Statins and risk of treated incident diabetes in a primary care population
    • doi: 10.1111/j.1365-2125.2012.04403.x
    • Zaharan NL, Williams D, Bennett K. Statins and risk of treated incident diabetes in a primary care population. Br J Clin Pharmacol. 2012. doi: 10.1111/j.1365-2125.2012.04403.x.
    • (2012) Br J Clin Pharmacol.
    • Zaharan, N.L.1    Williams, D.2    Bennett, K.3
  • 141
    • 0024360030 scopus 로고
    • Endothelium and control of vascular function. State of the art lecture
    • Vanhoutte PM. Endothelium and control of vascular function. State of the Art lecture. Hypertension. 1989;13(6 Pt 2):658-67. (Pubitemid 19157952)
    • (1989) Hypertension , vol.13 , Issue.6 , pp. 658-667
    • Vanhoutte, P.M.1
  • 145
    • 0031886203 scopus 로고    scopus 로고
    • Circulating levels of endothelin-1 during acute hyperinsulinemia in patients with essential hypertension treated with type 1 angiotensin receptor antagonist or placebo
    • DOI 10.1016/S0026-0495(98)90259-1
    • Seljeflot I, Moan A, Aspelin T, Tonnessen T, Kjeldsen SE, Arnesen H. Circulating levels of endothelin-1 during acute hyperinsulinemia in patients with essential hypertension treated with type 1 angiotensin receptor antagonist or placebo. Metab Clin Exp. 1998;47(3):292-6. (Pubitemid 28108776)
    • (1998) Metabolism: Clinical and Experimental , vol.47 , Issue.3 , pp. 292-296
    • Seljeflot, I.1    Moan, A.2    Aspelin, T.3    Tonnessen, T.4    Kjeldsen, S.E.5    Arnesen, H.6
  • 148
    • 0036737545 scopus 로고    scopus 로고
    • NCX 4016, a nitric oxide-releasing aspirin, modulates adrenergic vasoconstriction in the perfused rat tail artery
    • 12208780 1:CAS:528:DC%2BD38XnsV2ktr4%3D 10.1038/sj.bjp.0704869
    • Rossoni G, Manfredi B, Del Soldato P, Berti F. NCX 4016, a nitric oxide-releasing aspirin, modulates adrenergic vasoconstriction in the perfused rat tail artery. Br J Pharmacol. 2002;137(2):229-36.
    • (2002) Br J Pharmacol , vol.137 , Issue.2 , pp. 229-236
    • Rossoni, G.1    Manfredi, B.2    Del Soldato, P.3    Berti, F.4
  • 150
    • 84871299118 scopus 로고    scopus 로고
    • Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes
    • Shemyakin A, Kovamees O, Rafnsson A, Bohm F, Svenarud P, Settergren M, et al. Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes. Circulation. 2012;126(25):2943-50.
    • (2012) Circulation , vol.126 , Issue.25 , pp. 2943-50
    • Shemyakin, A.1    Kovamees, O.2    Rafnsson, A.3    Bohm, F.4    Svenarud, P.5    Settergren, M.6
  • 151
    • 0033752910 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus
    • 11126415 1:CAS:528:DC%2BD3cXnsFWhsrY%3D 10.1007/s001250051551
    • Heitzer T, Krohn K, Albers S, Meinertz T. Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus. Diabetologia. 2000;43(11):1435-8.
    • (2000) Diabetologia , vol.43 , Issue.11 , pp. 1435-1438
    • Heitzer, T.1    Krohn, K.2    Albers, S.3    Meinertz, T.4
  • 152
    • 10044245949 scopus 로고    scopus 로고
    • GTP cyclohydrolase I gene transfer reverses tetrahydrobiopterin deficiency and increases nitric oxide synthesis in endothelial cells and isolated vessels from diabetic rats
    • DOI 10.1096/fj.04-1702fje
    • Meininger CJ, Cai S, Parker JL, Channon KM, Kelly KA, Becker EJ, et al. GTP cyclohydrolase I gene transfer reverses tetrahydrobiopterin deficiency and increases nitric oxide synthesis in endothelial cells and isolated vessels from diabetic rats. FASEB J Off Publ Fed Am Soc Exp Biol. 2004;18(15):1900-2. (Pubitemid 39602277)
    • (2004) FASEB Journal , vol.18 , Issue.15 , pp. 1900-1902
    • Meininger, C.J.1    Cai, S.2    Parker, J.L.3    Channon, K.M.4    Kelly, K.A.5    Becker, E.J.6    Wood, M.K.7    Wade, L.A.8    Wu, G.9
  • 153
    • 6044230924 scopus 로고    scopus 로고
    • Tetrahydrobiopterin increases insulin sensitivity in patients with type 2 diabetes and coronary heart disease
    • DOI 10.1152/ajpendo.00046.2004
    • Nystrom T, Nygren A, Sjoholm A. Tetrahydrobiopterin increases insulin sensitivity in patients with type 2 diabetes and coronary heart disease. Am J Physiol Endocrinol Metab. 2004;287(5):E919-25. (Pubitemid 39382928)
    • (2004) American Journal of Physiology - Endocrinology and Metabolism , vol.287 , Issue.5
    • Nystrom, T.1    Nygren, A.2    Sjoholm, A.3
  • 154
    • 0033812927 scopus 로고    scopus 로고
    • Acute elevations of plasma asymmetric dimethylarginine and impaired endothelial function in response to a high-fat meal in patients with type 2 diabetes
    • 10978246 1:CAS:528:DC%2BD3cXntV2it7w%3D 10.1161/01.ATV.20.9.2039
    • Fard A, Tuck CH, Donis JA, Sciacca R, Di Tullio MR, Wu HD, et al. Acute elevations of plasma asymmetric dimethylarginine and impaired endothelial function in response to a high-fat meal in patients with type 2 diabetes. Arterioscler Thromb Vasc Biol. 2000;20(9):2039-44.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , Issue.9 , pp. 2039-2044
    • Fard, A.1    Tuck, C.H.2    Donis, J.A.3    Sciacca, R.4    Di Tullio, M.R.5    Wu, H.D.6
  • 155
    • 53649087556 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA) and other endogenous nitric oxide synthase (NOS) inhibitors as an important cause of vascular insulin resistance
    • 1:CAS:528:DC%2BD1cXhtlamtb3I 10.1055/s-0028-1083814
    • Toutouzas K, Riga M, Stefanadi E, Stefanadis C. Asymmetric dimethylarginine (ADMA) and other endogenous nitric oxide synthase (NOS) inhibitors as an important cause of vascular insulin resistance. Horm Metab Res Horm Stoffwechselforschung Horm Metab. 2008;40(9):655-9.
    • (2008) Horm Metab Res Horm Stoffwechselforschung Horm Metab , vol.40 , Issue.9 , pp. 655-659
    • Toutouzas, K.1    Riga, M.2    Stefanadi, E.3    Stefanadis, C.4
  • 156
    • 84870671592 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine plasma levels and endothelial function in newly diagnosed type 2 diabetic patients
    • 23203035 1:CAS:528:DC%2BC38Xhs1KisbrL 10.3390/ijms131113804
    • Sciacqua A, Grillo N, Quero M, Sesti G, Perticone F. Asymmetric dimethylarginine plasma levels and endothelial function in newly diagnosed type 2 diabetic patients. Int J Mol Sci. 2012;13(11):13804-15.
    • (2012) Int J Mol Sci , vol.13 , Issue.11 , pp. 13804-13815
    • Sciacqua, A.1    Grillo, N.2    Quero, M.3    Sesti, G.4    Perticone, F.5
  • 157
    • 33745133405 scopus 로고    scopus 로고
    • Epigallocatechin gallate preserves endothelial function by reducing the endogenous nitric oxide synthase inhibitor level
    • DOI 10.1139/y05-156
    • Tang WJ, Hu CP, Chen MF, Deng PY, Li YJ. Epigallocatechin gallate preserves endothelial function by reducing the endogenous nitric oxide synthase inhibitor level. Can J Physiol Pharmacol. 2006;84(2):163-71. (Pubitemid 43901424)
    • (2006) Canadian Journal of Physiology and Pharmacology , vol.84 , Issue.2 , pp. 163-171
    • Tang, W.-J.1    Hu, C.-P.2    Chen, M.-F.3    Deng, P.-Y.4    Li, Y.-J.5
  • 158
    • 33644817175 scopus 로고    scopus 로고
    • Effect of fenofibrate on the level of asymmetric dimethylarginine in individuals with hypertriglyceridemia
    • DOI 10.1007/s00228-005-0095-6
    • Yang TL, Chen MF, Xia X, Luo BL, Li YJ. Effect of fenofibrate on the level of asymmetric dimethylarginine in individuals with hypertriglyceridemia. Eur J Clin Pharmacol. 2006;62(3):179-84. (Pubitemid 43357575)
    • (2006) European Journal of Clinical Pharmacology , vol.62 , Issue.3 , pp. 179-184
    • Yang, T.-L.1    Chen, M.-F.2    Xia, X.3    Luo, B.-L.4    Li, Y.-J.5
  • 159
    • 36349034042 scopus 로고    scopus 로고
    • Effect of Telmisartan on Forearm Postischemic Hyperemia and Serum Asymmetric Dimethylarginine Levels
    • DOI 10.1016/j.amjhyper.2007.07.013, PII S089570610700430X
    • Tomiyama H, Yamada J, Koji Y, Shiina K, Yoshida M, Yamashina A. Effect of telmisartan on forearm postischemic hyperemia and serum asymmetric dimethylarginine levels. Am J Hypertens. 2007;20(12):1305-11. (Pubitemid 350151686)
    • (2007) American Journal of Hypertension , vol.20 , Issue.12 , pp. 1305-1311
    • Tomiyama, H.1    Yamada, J.2    Koji, Y.3    Shiina, K.4    Yoshida, M.5    Yamashina, A.6
  • 160
    • 42749096663 scopus 로고    scopus 로고
    • Effect of atorvastatin on plasma levels of asymmetric dimethylarginine in patients with non-ischaemic heart failure
    • 1:CAS:528:DC%2BD1cXls1yqur0%3D 10.1016/j.ejheart.2008.03.010
    • Young JM, Strey CH, George PM, Florkowski CM, Sies CW, Frampton CM, et al. Effect of atorvastatin on plasma levels of asymmetric dimethylarginine in patients with non-ischaemic heart failure. Eur J Hear Fail. 2008;10(5):463-6.
    • (2008) Eur J Hear Fail , vol.10 , Issue.5 , pp. 463-466
    • Young, J.M.1    Strey, C.H.2    George, P.M.3    Florkowski, C.M.4    Sies, C.W.5    Frampton, C.M.6
  • 161
    • 33847362727 scopus 로고    scopus 로고
    • Relationship between chronic tadalafil administration and improvement of endothelial function in men with erectile dysfunction: A pilot study
    • DOI 10.1038/sj.ijir.3901513, PII 3901513
    • Aversa A, Greco E, Bruzziches R, Pili M, Rosano G, Spera G. Relationship between chronic tadalafil administration and improvement of endothelial function in men with erectile dysfunction: a pilot study. Int J Impot Res. 2007;19(2):200-7. (Pubitemid 46340840)
    • (2007) International Journal of Impotence Research , vol.19 , Issue.2 , pp. 200-207
    • Aversa, A.1    Greco, E.2    Bruzziches, R.3    Pili, M.4    Rosano, G.5    Spera, G.6
  • 162
    • 38049187090 scopus 로고    scopus 로고
    • Chronic administration of Sildenafil improves markers of endothelial function in men with Type 2 diabetes
    • 1:CAS:528:DC%2BD1cXis1ahs7Y%3D 10.1111/j.1464-5491.2007.02298.x
    • Aversa A, Vitale C, Volterrani M, Fabbri A, Spera G, Fini M, et al. Chronic administration of Sildenafil improves markers of endothelial function in men with Type 2 diabetes. Diabet Med J Br Diabet Assoc. 2008;25(1):37-44.
    • (2008) Diabet Med J Br Diabet Assoc , vol.25 , Issue.1 , pp. 37-44
    • Aversa, A.1    Vitale, C.2    Volterrani, M.3    Fabbri, A.4    Spera, G.5    Fini, M.6
  • 164
    • 0036895991 scopus 로고    scopus 로고
    • Endothelin contributes to basal vascular tone and endothelial dysfunction in human obesity and type 2 diabetes
    • Mather KJ, Mirzamohammadi B, Lteif A, Steinberg HO, Baron AD. Endothelin contributes to basal vascular tone and endothelial dysfunction in human obesity and type 2 diabetes. Diabetes. 2002;51(12):3517-23. (Pubitemid 35403459)
    • (2002) Diabetes , vol.51 , Issue.12 , pp. 3517-3523
    • Mather, K.J.1    Mirzamohammadi, B.2    Lteif, A.3    Steinberg, H.O.4    Baron, A.D.5
  • 165
    • 33745685243 scopus 로고    scopus 로고
    • Enhanced endothelium-dependent vasodilatation by dual endothelin receptor blockade in individuals with insulin resistance
    • DOI 10.1097/01.fjc.0000210070.47205.16, PII 0000534420060300000008
    • Shemyakin A, Bohm F, Wagner H, Efendic S, Bavenholm P, Pernow J. Enhanced endothelium-dependent vasodilatation by dual endothelin receptor blockade in individuals with insulin resistance. J Cardiovasc Pharmacol. 2006;47(3):385-90. (Pubitemid 44309691)
    • (2006) Journal of Cardiovascular Pharmacology , vol.47 , Issue.3 , pp. 385-390
    • Shemyakin, A.1    Bohm, F.2    Wagner, H.3    Efendic, S.4    Bavenholm, P.5    Pernow, J.6
  • 166
    • 84856743561 scopus 로고    scopus 로고
    • The endothelin receptor antagonist bosentan improves peripheral endothelial function in patients with type 2 diabetes mellitus and microalbuminuria: A randomised trial
    • 22200728 1:CAS:528:DC%2BC38Xhsl2gtL4%3D 10.1007/s00125-011-2415-y
    • Rafnsson A, Bohm F, Settergren M, Gonon A, Brismar K, Pernow J. The endothelin receptor antagonist bosentan improves peripheral endothelial function in patients with type 2 diabetes mellitus and microalbuminuria: a randomised trial. Diabetologia. 2012;55(3):600-7.
    • (2012) Diabetologia , vol.55 , Issue.3 , pp. 600-607
    • Rafnsson, A.1    Bohm, F.2    Settergren, M.3    Gonon, A.4    Brismar, K.5    Pernow, J.6
  • 167
    • 0036311315 scopus 로고    scopus 로고
    • Enhanced endothelin activity prevents vasodilation to insulin in insulin resistance
    • DOI 10.1161/01.HYP.0000022806.87281.62
    • Miller AW, Tulbert C, Puskar M, Busija DW. Enhanced endothelin activity prevents vasodilation to insulin in insulin resistance. Hypertension. 2002;40(1):78-82. (Pubitemid 34755983)
    • (2002) Hypertension , vol.40 , Issue.1 , pp. 78-82
    • Miller, A.W.1    Tulbert, C.2    Puskar, M.3    Busija, D.W.4
  • 168
    • 33847625532 scopus 로고    scopus 로고
    • Dual endothelin receptor blockade acutely improves insulin sensitivity in obese patients with insulin resistance and coronary artery disease
    • DOI 10.2337/dc06-1978
    • Ahlborg G, Shemyakin A, Bohm F, Gonon A, Pernow J. Dual endothelin receptor blockade acutely improves insulin sensitivity in obese patients with insulin resistance and coronary artery disease. Diabetes Care. 2007;30(3):591-6. (Pubitemid 46354339)
    • (2007) Diabetes Care , vol.30 , Issue.3 , pp. 591-596
    • Ahlborg, G.1    Shemyakin, A.2    Bohm, F.3    Gonon, A.4    Pernow, J.5
  • 169
    • 33847404040 scopus 로고    scopus 로고
    • Endothelin limits insulin action in obese/insulin-resistant humans
    • DOI 10.2337/db06-1406
    • Lteif A, Vaishnava P, Baron AD, Mather KJ. Endothelin limits insulin action in obese/insulin-resistant humans. Diabetes. 2007;56(3):728-34. (Pubitemid 46348477)
    • (2007) Diabetes , vol.56 , Issue.3 , pp. 728-734
    • Lteif, A.1    Vaishnava, P.2    Baron, A.D.3    Mather, K.J.4
  • 170
    • 1242294387 scopus 로고    scopus 로고
    • A Constituent of Green Tea, Epigallocatechin-3-gallate, Activates Endothelial Nitric Oxide Synthase by a Phosphatidylinositol-3-OH-kinase-, cAMP-dependent Protein Kinase-, and Akt-dependent Pathway and Leads to Endothelial-dependent Vasorelaxation
    • DOI 10.1074/jbc.M309114200
    • Lorenz M, Wessler S, Follmann E, Michaelis W, Dusterhoft T, Baumann G, et al. A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation. J Biol Chem. 2004;279(7):6190-5. (Pubitemid 38220652)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 6190-6195
    • Lorenz, M.1    Wessler, S.2    Follmann, E.3    Michaelis, W.4    Dusterhoft, T.5    Baumann, G.6    Stangl, K.7    Stangl, V.8
  • 171
    • 34250174411 scopus 로고    scopus 로고
    • Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and fyn
    • DOI 10.1074/jbc.M609725200
    • Kim JA, Formoso G, Li Y, Potenza MA, Marasciulo FL, Montagnani M, et al. Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn. J Biol Chem. 2007;282(18):13736-45. (Pubitemid 47100559)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.18 , pp. 13736-13745
    • Kim, J.-A.1    Formoso, G.2    Li, Y.3    Potenza, M.A.4    Marasciulo, F.L.5    Montagnani, M.6    Quon, M.J.7
  • 175
    • 82455219002 scopus 로고    scopus 로고
    • The impact of the catechol-O-methyltransferase genotype on the acute responsiveness of vascular reactivity to a green tea extract
    • 21144097 10.1017/S0007114510004836
    • Miller RJ, Jackson KG, Dadd T, Mayes AE, Brown AL, Minihane AM. The impact of the catechol-O-methyltransferase genotype on the acute responsiveness of vascular reactivity to a green tea extract. Br J Nutr. 2011;105(8):1138-44.
    • (2011) Br J Nutr , vol.105 , Issue.8 , pp. 1138-1144
    • Miller, R.J.1    Jackson, K.G.2    Dadd, T.3    Mayes, A.E.4    Brown, A.L.5    Minihane, A.M.6
  • 176
    • 33746581658 scopus 로고    scopus 로고
    • Dehydroepiandrosterone mimics acute actions of insulin to stimulate production of both nitric oxide and endothelin 1 via distinct phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-dependent pathways in vascular endothelium
    • 16373398 1:CAS:528:DC%2BD28XksleqsLk%3D 10.1210/me.2005-0266
    • Formoso G, Chen H, Kim JA, Montagnani M, Consoli A, Quon MJ. Dehydroepiandrosterone mimics acute actions of insulin to stimulate production of both nitric oxide and endothelin 1 via distinct phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-dependent pathways in vascular endothelium. Mol Endocrinol. 2006;20(5):1153-63.
    • (2006) Mol Endocrinol , vol.20 , Issue.5 , pp. 1153-1163
    • Formoso, G.1    Chen, H.2    Kim, J.A.3    Montagnani, M.4    Consoli, A.5    Quon, M.J.6
  • 178
    • 84859530935 scopus 로고    scopus 로고
    • Effects of cigarette smoking, metabolic syndrome and dehydroepiandrosterone deficiency on intima-media thickness and endothelial function in hypertensive postmenopausal women
    • 1:CAS:528:DC%2BC38XhtlWgs7zI
    • Mieczkowska J, Mosiewicz J, Sak J, Grzybowski A, Terlecki P, Barud W, et al. Effects of cigarette smoking, metabolic syndrome and dehydroepiandrosterone deficiency on intima-media thickness and endothelial function in hypertensive postmenopausal women. Med Sci Monit Int Med J Exp Clin Res. 2012;18(4):CR225-34.
    • (2012) Med Sci Monit Int Med J Exp Clin Res , vol.18 , Issue.4
    • Mieczkowska, J.1    Mosiewicz, J.2    Sak, J.3    Grzybowski, A.4    Terlecki, P.5    Barud, W.6
  • 181
    • 0037167677 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase
    • 12270858 1:CAS:528:DC%2BD38XntVynsbg%3D 10.1161/01.CIR.0000029925.18593. 5C
    • Wallerath T, Deckert G, Ternes T, Anderson H, Li H, Witte K, et al. Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase. Circulation. 2002;106(13):1652-8.
    • (2002) Circulation , vol.106 , Issue.13 , pp. 1652-1658
    • Wallerath, T.1    Deckert, G.2    Ternes, T.3    Anderson, H.4    Li, H.5    Witte, K.6
  • 182
    • 79951788944 scopus 로고    scopus 로고
    • Red wine polyphenols prevent endothelial dysfunction induced by endothelin-1 in rat aorta: Role of NADPH oxidase
    • 20977430 1:CAS:528:DC%2BC3MXmsVCmur0%3D 10.1042/CS20100311
    • Lopez-Sepulveda R, Gomez-Guzman M, Zarzuelo MJ, Romero M, Sanchez M, Quintela AM, et al. Red wine polyphenols prevent endothelial dysfunction induced by endothelin-1 in rat aorta: role of NADPH oxidase. Clin Sci. 2011;120(8):321-33.
    • (2011) Clin Sci , vol.120 , Issue.8 , pp. 321-333
    • Lopez-Sepulveda, R.1    Gomez-Guzman, M.2    Zarzuelo, M.J.3    Romero, M.4    Sanchez, M.5    Quintela, A.M.6
  • 183
    • 77953050012 scopus 로고    scopus 로고
    • Physiological concentrations of dietary polyphenols regulate vascular endothelial cell expression of genes important in cardiovascular health
    • 20021702 1:CAS:528:DC%2BC3cXmtFWqs7s%3D 10.1017/S0007114509993485
    • Nicholson SK, Tucker GA, Brameld JM. Physiological concentrations of dietary polyphenols regulate vascular endothelial cell expression of genes important in cardiovascular health. Br J Nutr. 2010;103(10):1398-403.
    • (2010) Br J Nutr , vol.103 , Issue.10 , pp. 1398-1403
    • Nicholson, S.K.1    Tucker, G.A.2    Brameld, J.M.3
  • 184
    • 82455220960 scopus 로고    scopus 로고
    • Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment
    • 22118755 1:CAS:528:DC%2BC3MXhsFehu7jL 10.1016/j.nutres.2011.09.028
    • Fujitaka K, Otani H, Jo F, Jo H, Nomura E, Iwasaki M, et al. Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment. Nutr Res. 2011;31(11):842-7.
    • (2011) Nutr Res , vol.31 , Issue.11 , pp. 842-847
    • Fujitaka, K.1    Otani, H.2    Jo, F.3    Jo, H.4    Nomura, E.5    Iwasaki, M.6
  • 185
    • 84950170835 scopus 로고    scopus 로고
    • Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure
    • 1:CAS:528:DC%2BC3MXhtlejsbzN 10.1016/j.numecd.2010.03.003
    • Wong RH, Howe PR, Buckley JD, Coates AM, Kunz I, Berry NM. Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure. Nutr Metab Cardiovasc Dis NMCD. 2011;21(11):851-6.
    • (2011) Nutr Metab Cardiovasc Dis NMCD , vol.21 , Issue.11 , pp. 851-856
    • Wong, R.H.1    Howe, P.R.2    Buckley, J.D.3    Coates, A.M.4    Kunz, I.5    Berry, N.M.6
  • 186
    • 84857932052 scopus 로고    scopus 로고
    • Role of microRNAs in diabetes and its cardiovascular complications
    • 22065734 1:CAS:528:DC%2BC38XjtlKksr0%3D 10.1093/cvr/cvr300
    • Shantikumar S, Caporali A, Emanueli C. Role of microRNAs in diabetes and its cardiovascular complications. Cardiovasc Res. 2012;93(4):583-93.
    • (2012) Cardiovasc Res , vol.93 , Issue.4 , pp. 583-593
    • Shantikumar, S.1    Caporali, A.2    Emanueli, C.3
  • 188
    • 33644790277 scopus 로고    scopus 로고
    • Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: Implications in atherogenesis
    • DOI 10.1161/01.ATV.0000189159.96900.d9, PII 0004360520051200000028
    • Dickhout JG, Hossain GS, Pozza LM, Zhou J, Lhotak S, Austin RC. Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arterioscler Thromb Vasc Biol. 2005;25(12):2623-9. (Pubitemid 43732288)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.12 , pp. 2623-2629
    • Dickhout, J.G.1    Hossain, G.S.2    Pozza, L.M.3    Zhou, J.4    Lhotak, S.5    Austin, R.C.6
  • 189
    • 77957764137 scopus 로고    scopus 로고
    • Hyperglycemia-induced endoplasmic reticulum stress in endothelial cells
    • 20080028 1:CAS:528:DC%2BC3cXht12ltb7O 10.1016/j.nut.2009.08.019
    • Sheikh-Ali M, Sultan S, Alamir AR, Haas MJ, Mooradian AD. Hyperglycemia-induced endoplasmic reticulum stress in endothelial cells. Nutrition. 2010;26(11-12):1146-50.
    • (2010) Nutrition , vol.26 , Issue.11-12 , pp. 1146-1150
    • Sheikh-Ali, M.1    Sultan, S.2    Alamir, A.R.3    Haas, M.J.4    Mooradian, A.D.5
  • 190
    • 84864120303 scopus 로고    scopus 로고
    • Translational evidence that impaired autophagy contributes to arterial ageing
    • 22570377 1:CAS:528:DC%2BC38Xht1Oks7bN 10.1113/jphysiol.2012.229690
    • LaRocca TJ, Henson GD, Thorburn A, Sindler AL, Pierce GL, Seals DR. Translational evidence that impaired autophagy contributes to arterial ageing. J Physiol. 2012;590(Pt 14):3305-16.
    • (2012) J Physiol , vol.590 , Issue.PART 14 , pp. 3305-3316
    • Larocca, T.J.1    Henson, G.D.2    Thorburn, A.3    Sindler, A.L.4    Pierce, G.L.5    Seals, D.R.6
  • 191
    • 77950188875 scopus 로고    scopus 로고
    • The autophagy-lysosome pathway: A novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells
    • 20223224 1:CAS:528:DC%2BC3cXksVentrw%3D 10.1016/j.bbrc.2010.03.026
    • Zhang YL, Cao YJ, Zhang X, Liu HH, Tong T, Xiao GD, et al. The autophagy-lysosome pathway: a novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells. Biochem Biophys Res Commun. 2010;394(2):377-82.
    • (2010) Biochem Biophys Res Commun , vol.394 , Issue.2 , pp. 377-382
    • Zhang, Y.L.1    Cao, Y.J.2    Zhang, X.3    Liu, H.H.4    Tong, T.5    Xiao, G.D.6
  • 192
    • 84870902173 scopus 로고    scopus 로고
    • Targeted estrogen delivery reverses the metabolic syndrome
    • 23142820 1:CAS:528:DC%2BC38Xhs1CktL7F 10.1038/nm.3009
    • Finan B, Yang B, Ottaway N, Stemmer K, Muller TD, Yi CX, et al. Targeted estrogen delivery reverses the metabolic syndrome. Nat Med. 2012;18(12):1847-56.
    • (2012) Nat Med , vol.18 , Issue.12 , pp. 1847-1856
    • Finan, B.1    Yang, B.2    Ottaway, N.3    Stemmer, K.4    Muller, T.D.5    Yi, C.X.6
  • 193
    • 77953832068 scopus 로고    scopus 로고
    • Acute hormonal changes following intravenous glucose challenge in lean and obese human subjects
    • 1:CAS:528:DC%2BC3cXnslams7w%3D 10.3109/00365511003792975
    • Haltia LT, Savontaus E, Vahlberg T, Rinne JO, Kaasinen V. Acute hormonal changes following intravenous glucose challenge in lean and obese human subjects. Scand J Clin Lab Investig. 2010;70(4):275-80.
    • (2010) Scand J Clin Lab Investig , vol.70 , Issue.4 , pp. 275-280
    • Haltia, L.T.1    Savontaus, E.2    Vahlberg, T.3    Rinne, J.O.4    Kaasinen, V.5


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