-
2
-
-
0018372943
-
Kinetics of native insulin in diabetic, obese, and aged men
-
EA McGuire JD Tobin M Berman R Andres 1979 Kinetics of native insulin in diabetic, obese, and aged men Diabetes 28 110 120
-
(1979)
Diabetes
, vol.28
, pp. 110-120
-
-
McGuire, E.A.1
Tobin, J.D.2
Berman, M.3
Andres, R.4
-
3
-
-
0018520840
-
Glucose clamp technique, a method for quantifying insulin secretion and resistance
-
RA DeFronzo JD Tobin R Andres 1979 Glucose clamp technique, a method for quantifying insulin secretion and resistance Am J Physiol 237 E214 E223
-
(1979)
Am J Physiol
, vol.237
-
-
Defronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
4
-
-
0026482680
-
Tissue uptake of insulin and inulin in red and white skeletal muscle in vivo
-
A Holmang P Bjorntorp B Rippe 1992 Tissue uptake of insulin and inulin in red and white skeletal muscle in vivo Am J Physiol 263 H1170 H1176
-
(1992)
Am J Physiol
, vol.263
-
-
Holmang, A.1
Bjorntorp, P.2
Rippe, B.3
-
5
-
-
0028847791
-
The effects of non-insulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues
-
D Turk A Alzaid S Dinneen KS Nair R Rizza 1995 The effects of non-insulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues J Clin Invest 95 755 762
-
(1995)
J Clin Invest
, vol.95
, pp. 755-762
-
-
Turk, D.1
Alzaid, A.2
Dinneen, S.3
Nair, K.S.4
Rizza, R.5
-
6
-
-
0022500793
-
In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects
-
R Prager P Wallace JM Olefsky 1986 In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects J Clin Invest 78 472 481
-
(1986)
J Clin Invest
, vol.78
, pp. 472-481
-
-
Prager, R.1
Wallace, P.2
Olefsky, J.M.3
-
7
-
-
0021994683
-
Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus
-
R DeFronzo R Gunnarsson O Ojorkman M Olsson J Wahren 1985 Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus J Clin Invest 76 149 155
-
(1985)
J Clin Invest
, vol.76
, pp. 149-155
-
-
Defronzo, R.1
Gunnarsson, R.2
Ojorkman, O.3
Olsson, M.4
Wahren, J.5
-
8
-
-
33846849237
-
Phenotypic heterogeneity of the endothelium: II. Representative vascular beds
-
WC Aird 2007 Phenotypic heterogeneity of the endothelium: II. Representative vascular beds Circ Res 100 174 190
-
(2007)
Circ Res
, vol.100
, pp. 174-190
-
-
Aird, W.C.1
-
9
-
-
33846798106
-
Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms
-
WC Aird 2007 Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms Circ Res 100 158 173
-
(2007)
Circ Res
, vol.100
, pp. 158-173
-
-
Aird, W.C.1
-
10
-
-
0030911521
-
Insulin receptor substrate (IRS)-2 is dephosphorylated more rapidly than IRS-1 via its association with phosphatidylinositol 3-kinase in skeletal muscle cells
-
T Ogihara B-C Shin M Anai 1997 Insulin receptor substrate (IRS)-2 is dephosphorylated more rapidly than IRS-1 via its association with phosphatidylinositol 3-kinase in skeletal muscle cells J Biol Chem 272 12868 12873
-
(1997)
J Biol Chem
, vol.272
, pp. 12868-12873
-
-
Ogihara, T.1
Shin, B.-C.2
Anai, M.3
-
11
-
-
0019861360
-
Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. Time course, reversal, insulin concentration dependency, and relationship to glucose transport activity
-
E Karnieli MJ Zarnowski PJ Hissin IA Simpson LB Salans SW Cushman 1981 Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. Time course, reversal, insulin concentration dependency, and relationship to glucose transport activity J Biol Chem 256 4772 4777
-
(1981)
J Biol Chem
, vol.256
, pp. 4772-4777
-
-
Karnieli, E.1
Zarnowski, M.J.2
Hissin, P.J.3
Simpson, I.A.4
Salans, L.B.5
Cushman, S.W.6
-
12
-
-
0024423823
-
Insulin transport across capillaries is rate limiting for insulin action in dogs
-
YJ Yang ID Hope M Ader RN Bergman 1989 Insulin transport across capillaries is rate limiting for insulin action in dogs J Clin Invest 84 1620 1628
-
(1989)
J Clin Invest
, vol.84
, pp. 1620-1628
-
-
Yang, Y.J.1
Hope, I.D.2
Ader, M.3
Bergman, R.N.4
-
13
-
-
0026584423
-
Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues
-
YJ Yang I Hope M Ader RA Poulin RN Bergman 1992 Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues Diabetes 41 241 253
-
(1992)
Diabetes
, vol.41
, pp. 241-253
-
-
Yang, Y.J.1
Hope, I.2
Ader, M.3
Poulin, R.A.4
Bergman, R.N.5
-
14
-
-
0028097682
-
Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph
-
RA Poulin GM Steil DM Moore M Ader RN Bergman 1994 Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph Diabetes 43 180 190
-
(1994)
Diabetes
, vol.43
, pp. 180-190
-
-
Poulin, R.A.1
Steil, G.M.2
Moore, D.M.3
Ader, M.4
Bergman, R.N.5
-
16
-
-
0028153563
-
Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men
-
C Castillo C Bogardus R Bergman P Thuillez S Lillioja 1994 Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men J Clin Invest 93 10 16
-
(1994)
J Clin Invest
, vol.93
, pp. 10-16
-
-
Castillo, C.1
Bogardus, C.2
Bergman, R.3
Thuillez, P.4
Lillioja, S.5
-
20
-
-
0037327859
-
Transcapillary insulin transfer in human skeletal muscle
-
H Herkner N Klein C Joukhadar 2003 Transcapillary insulin transfer in human skeletal muscle Eur J Clin Invest 33 141 146
-
(2003)
Eur J Clin Invest
, vol.33
, pp. 141-146
-
-
Herkner, H.1
Klein, N.2
Joukhadar, C.3
-
22
-
-
0030669621
-
Interstitial muscle insulin and glucose levels in normal and insulin-resistant Zucker rats
-
A Holmang K Mimura P Bjorntorp P Lonnroth 1997 Interstitial muscle insulin and glucose levels in normal and insulin-resistant Zucker rats Diabetes 46 1799 1804
-
(1997)
Diabetes
, vol.46
, pp. 1799-1804
-
-
Holmang, A.1
Mimura, K.2
Bjorntorp, P.3
Lonnroth, P.4
-
23
-
-
0028314849
-
Changes in skin circulation after insertion of a microdialysis probe visualized by laser Doppler perfusion imaging
-
C Anderson T Andersson K Wardell 1994 Changes in skin circulation after insertion of a microdialysis probe visualized by laser Doppler perfusion imaging J Invest Dermatol 102 807 811
-
(1994)
J Invest Dermatol
, vol.102
, pp. 807-811
-
-
Anderson, C.1
Andersson, T.2
Wardell, K.3
-
24
-
-
0018759347
-
Interrelationships of glucose and insulin uptake by muscle of normal and diabetic man. Evidence of a difference in metabolism of endogenous and exogenous insulin
-
N Kalant T Leibovici I Rohan S Ozaki 1979 Interrelationships of glucose and insulin uptake by muscle of normal and diabetic man. Evidence of a difference in metabolism of endogenous and exogenous insulin Diabetologia 16 365 372
-
(1979)
Diabetologia
, vol.16
, pp. 365-372
-
-
Kalant, N.1
Leibovici, T.2
Rohan, I.3
Ozaki, S.4
-
25
-
-
36849086414
-
Hyperinsulinaemia rapidly increases human muscle microvascular perfusion but fails to increase muscle insulin clearance: Evidence that a saturable process mediates muscle insulin uptake
-
EM Eggleston LA Jahn EJ Barrett 2007 Hyperinsulinaemia rapidly increases human muscle microvascular perfusion but fails to increase muscle insulin clearance: evidence that a saturable process mediates muscle insulin uptake Diabetes 56 2958 2963
-
(2007)
Diabetes
, vol.56
, pp. 2958-2963
-
-
Eggleston, E.M.1
Jahn, L.A.2
Barrett, E.J.3
-
26
-
-
0028246255
-
Limits to steady-state lymph flow rates derived from plasma-to-tissue uptake measurements
-
EM Renkin H Wiig 1994 Limits to steady-state lymph flow rates derived from plasma-to-tissue uptake measurements Microvasc Res 47 318 328
-
(1994)
Microvasc Res
, vol.47
, pp. 318-328
-
-
Renkin, E.M.1
Wiig, H.2
-
27
-
-
0022019629
-
Processing of cell-bound insulin by capillary and macrovascular endothelial cells in culture
-
KD Dernovsek RS Bar 1985 Processing of cell-bound insulin by capillary and macrovascular endothelial cells in culture Am J Physiol 248 E244 E251
-
(1985)
Am J Physiol
, vol.248
-
-
Dernovsek, K.D.1
Bar, R.S.2
-
28
-
-
0021151402
-
Processing of insulin by bovine endothelial cells in culture. Internalization without degradation
-
I Jialal GL King S Buchwald CR Kahn M Crettaz 1984 Processing of insulin by bovine endothelial cells in culture. Internalization without degradation Diabetes 33 794 800
-
(1984)
Diabetes
, vol.33
, pp. 794-800
-
-
Jialal, I.1
King, G.L.2
Buchwald, S.3
Kahn, C.R.4
Crettaz, M.5
-
29
-
-
0028085621
-
Hemodynamic actions of insulin
-
A Baron 1994 Hemodynamic actions of insulin Am J Physiol 267 E187 E202
-
(1994)
Am J Physiol
, vol.267
-
-
Baron, A.1
-
30
-
-
0025954408
-
Mechanism of insulin resistance in insulin-dependent diabetes mellitus: A major role for reduced skeletal muscle blood flow
-
AD Baron M Laakso G Brechtel SV Edelman 1991 Mechanism of insulin resistance in insulin-dependent diabetes mellitus: a major role for reduced skeletal muscle blood flow J Clin Endocrinol Metab 73 637 643
-
(1991)
J Clin Endocrinol Metab
, vol.73
, pp. 637-643
-
-
Baron, A.D.1
Laakso, M.2
Brechtel, G.3
Edelman, S.V.4
-
31
-
-
0025292440
-
Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man
-
M Laakso SV Edelman G Brechtel AD Baron 1990 Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man J Clin Invest 85 1844 1852
-
(1990)
J Clin Invest
, vol.85
, pp. 1844-1852
-
-
Laakso, M.1
Edelman, S.V.2
Brechtel, G.3
Baron, A.D.4
-
32
-
-
0026801899
-
Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM
-
M Laakso SV Edelman G Brechtel AD Baron 1992 Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM Diabetes 41 1076 1083
-
(1992)
Diabetes
, vol.41
, pp. 1076-1083
-
-
Laakso, M.1
Edelman, S.V.2
Brechtel, G.3
Baron, A.D.4
-
33
-
-
0027184924
-
Differential effects of hyperinsulinaemia and carbohydrate metabolism on sympathetic nerve activity and muscle blood flow in humans
-
P Vollenweider L Tappy D Randin 1993 Differential effects of hyperinsulinaemia and carbohydrate metabolism on sympathetic nerve activity and muscle blood flow in humans J Clin Invest 92 147 154
-
(1993)
J Clin Invest
, vol.92
, pp. 147-154
-
-
Vollenweider, P.1
Tappy, L.2
Randin, D.3
-
36
-
-
0031977203
-
Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance-effects of troglitazone
-
CJJ Tack MKE Ong JA Lutterman P Smits 1998 Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance-effects of troglitazone Diabetologia 41 569 576
-
(1998)
Diabetologia
, vol.41
, pp. 569-576
-
-
Tack, C.J.J.1
Ong, M.K.E.2
Lutterman, J.A.3
Smits, P.4
-
37
-
-
0031920445
-
Insulin-induced vasodilatation: Physiology or pharmacology
-
H Yki-Jarvinen T Utriainen 1998 Insulin-induced vasodilatation: physiology or pharmacology Diabetologia 41 369 379
-
(1998)
Diabetologia
, vol.41
, pp. 369-379
-
-
Yki-Jarvinen, H.1
Utriainen, T.2
-
38
-
-
0028800873
-
Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension
-
S Taddei A Virdis P Mattei A Natali E Ferrannini A Salvetti 1995 Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension Circulation 92 2911 2918
-
(1995)
Circulation
, vol.92
, pp. 2911-2918
-
-
Taddei, S.1
Virdis, A.2
Mattei, P.3
Natali, A.4
Ferrannini, E.5
Salvetti, A.6
-
39
-
-
0032555102
-
Role of tissue-specific blood flow and tissue recruitment in insulin-mediated glucose uptake of human skeletal muscle
-
RC Bonadonna MP Saccomani S Delprato E Bonora RA Defronzo C Cobelli 1998 Role of tissue-specific blood flow and tissue recruitment in insulin-mediated glucose uptake of human skeletal muscle Circulation 98 234 241
-
(1998)
Circulation
, vol.98
, pp. 234-241
-
-
Bonadonna, R.C.1
Saccomani, M.P.2
Delprato, S.3
Bonora, E.4
Defronzo, R.A.5
Cobelli, C.6
-
40
-
-
0028316832
-
Skeletal muscle blood flow independently modulates insulin-mediated glucose uptake
-
AD Baron H Steinberg G Brechtel A Johnson 1994 Skeletal muscle blood flow independently modulates insulin-mediated glucose uptake Am J Physiol 266 E248 E253
-
(1994)
Am J Physiol
, vol.266
-
-
Baron, A.D.1
Steinberg, H.2
Brechtel, G.3
Johnson, A.4
-
41
-
-
0028030813
-
Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent: A novel action of insulin to increase nitric oxide release
-
HO Steinberg G Brechtel A Johnson F Fineberg AD Baron 1994 Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent: a novel action of insulin to increase nitric oxide release J Clin Invest 94 1172 1179
-
(1994)
J Clin Invest
, vol.94
, pp. 1172-1179
-
-
Steinberg, H.O.1
Brechtel, G.2
Johnson, A.3
Fineberg, F.4
Baron, A.D.5
-
45
-
-
0025355902
-
Effects of insulin on hemodynamics and metabolism in human forearm
-
A Natali G Buzzigoli S Taddei 1990 Effects of insulin on hemodynamics and metabolism in human forearm Diabetes 39 490 500
-
(1990)
Diabetes
, vol.39
, pp. 490-500
-
-
Natali, A.1
Buzzigoli, G.2
Taddei, S.3
-
48
-
-
2642611091
-
Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity
-
M Laine H Ykijarvinen O Kirvela 1998 Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity J Clin Invest 101 1156 1162
-
(1998)
J Clin Invest
, vol.101
, pp. 1156-1162
-
-
Laine, M.1
Ykijarvinen, H.2
Kirvela, O.3
-
49
-
-
0029119084
-
Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans
-
AD Baron HO Steinberg H Chaker R Learning A Johnson G Brechtel 1995 Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans J Clin Invest 96 786 792
-
(1995)
J Clin Invest
, vol.96
, pp. 786-792
-
-
Baron, A.D.1
Steinberg, H.O.2
Chaker, H.3
Learning, R.4
Johnson, A.5
Brechtel, G.6
-
51
-
-
0030863236
-
Hemodynamic actions of insulin in rat skeletal muscle: Evidence for capillary recruitment
-
S Rattigan MG Clark EJ Barrett 1997 Hemodynamic actions of insulin in rat skeletal muscle: Evidence for capillary recruitment Diabetes 46 1381 1388
-
(1997)
Diabetes
, vol.46
, pp. 1381-1388
-
-
Rattigan, S.1
Clark, M.G.2
Barrett, E.J.3
-
52
-
-
0035656147
-
Physiologic hyperinsulinaemia enhances human skeletal muscle perfusion by capillary recruitment
-
MP Coggins J Lindner S Rattigan 2001 Physiologic hyperinsulinaemia enhances human skeletal muscle perfusion by capillary recruitment Diabetes 50 2682 2690
-
(2001)
Diabetes
, vol.50
, pp. 2682-2690
-
-
Coggins, M.P.1
Lindner, J.2
Rattigan, S.3
-
54
-
-
2542539954
-
Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo
-
MA Vincent LH Clerk JR Lindner 2004 Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo Diabetes 53 1418 1423
-
(2004)
Diabetes
, vol.53
, pp. 1418-1423
-
-
Vincent, M.A.1
Clerk, L.H.2
Lindner, J.R.3
-
55
-
-
0842266828
-
Insulin sensitivity of muscle capillary recruitment in vivo
-
L Zhang MA Vincent SM Richards 2004 Insulin sensitivity of muscle capillary recruitment in vivo Diabetes 53 447 453
-
(2004)
Diabetes
, vol.53
, pp. 447-453
-
-
Zhang, L.1
Vincent, M.A.2
Richards, S.M.3
-
59
-
-
0032972029
-
Acute insulin resistance in rat skeletal muscle in vivo induced by vasoconstriction
-
S Rattigan MG Clark EJ Barrett 1999 Acute insulin resistance in rat skeletal muscle in vivo induced by vasoconstriction Diabetes 48 564 569
-
(1999)
Diabetes
, vol.48
, pp. 564-569
-
-
Rattigan, S.1
Clark, M.G.2
Barrett, E.J.3
-
60
-
-
0029737713
-
Dilation of isolated skeletal muscle arterioles by insulin is endothelium dependent and nitric oxide mediated
-
YL Chen EJ Messina 1996 Dilation of isolated skeletal muscle arterioles by insulin is endothelium dependent and nitric oxide mediated Am J Physiol 270 H2120 H2124
-
(1996)
Am J Physiol
, vol.270
-
-
Chen, Y.L.1
Messina, E.J.2
-
61
-
-
0023726478
-
A study of the functional elements regulating capillary perfusion in striated muscle
-
JB Delashaw BR Duling 1988 A study of the functional elements regulating capillary perfusion in striated muscle Microvasc Res 36 162 171
-
(1988)
Microvasc Res
, vol.36
, pp. 162-171
-
-
Delashaw, J.B.1
Duling, B.R.2
-
62
-
-
0036889823
-
Physiological concentrations of insulin induce endothelin-mediated vasoconstriction during inhibition of NOS or PI3-kinase in skeletal muscle arterioles
-
EC Eringa CD Stehouwer T Merlijn N Westerhof P Sipkema 2002 Physiological concentrations of insulin induce endothelin-mediated vasoconstriction during inhibition of NOS or PI3-kinase in skeletal muscle arterioles Cardiovasc Res 56 464 471
-
(2002)
Cardiovasc Res
, vol.56
, pp. 464-471
-
-
Eringa, E.C.1
Stehouwer, C.D.2
Merlijn, T.3
Westerhof, N.4
Sipkema, P.5
-
63
-
-
0036316948
-
Direct evidence for insulin-induced capillary recruitment in skin of healthy subjects during physiological hyperinsulinemia
-
EH Serne RG IJzerman ROB Gans 2002 Direct evidence for insulin-induced capillary recruitment in skin of healthy subjects during physiological hyperinsulinemia Diabetes 51 1515 1522
-
(2002)
Diabetes
, vol.51
, pp. 1515-1522
-
-
Serne, E.H.1
Ijzerman, R.G.2
Gans, R.O.B.3
-
64
-
-
0033596638
-
Microvascular function relates to insulin sensitivity and blood pressure in normal subjects
-
EH Serne CD Stehouwer JC ter Maaten 1999 Microvascular function relates to insulin sensitivity and blood pressure in normal subjects Circulation 99 896 902
-
(1999)
Circulation
, vol.99
, pp. 896-902
-
-
Serne, E.H.1
Stehouwer, C.D.2
Ter Maaten, J.C.3
-
65
-
-
2642572617
-
Impaired microvascular function in obesity: Implications for obesity-associated microangiopathy, hypertension, and insulin resistance
-
RT de Jongh EH Serne RG IJzerman G de Vries CD Stehouwer 2004 Impaired microvascular function in obesity: implications for obesity-associated microangiopathy, hypertension, and insulin resistance Circulation 109 2529 2535
-
(2004)
Circulation
, vol.109
, pp. 2529-2535
-
-
De Jongh, R.T.1
Serne, E.H.2
Ijzerman, R.G.3
De Vries, G.4
Stehouwer, C.D.5
-
66
-
-
39049145743
-
Impaired local microvascular vasodilatory effects of insulin and reduced skin microvascular vasomotion in obese women
-
RT de Jongh EH Serne RG IJzerman HT Jorstad CD Stehouwer 2008 Impaired local microvascular vasodilatory effects of insulin and reduced skin microvascular vasomotion in obese women Microvasc Res 75 256 262
-
(2008)
Microvasc Res
, vol.75
, pp. 256-262
-
-
De Jongh, R.T.1
Serne, E.H.2
Ijzerman, R.G.3
Jorstad, H.T.4
Stehouwer, C.D.5
-
67
-
-
7044269441
-
Free fatty acid levels modulate microvascular function: Relevance for obesity-associated insulin resistance, hypertension, and microangiopathy
-
RT de Jongh EH Serne RG IJzerman G de Vries CD Stehouwer 2004 Free fatty acid levels modulate microvascular function: relevance for obesity-associated insulin resistance, hypertension, and microangiopathy Diabetes 53 2873 2882
-
(2004)
Diabetes
, vol.53
, pp. 2873-2882
-
-
De Jongh, R.T.1
Serne, E.H.2
Ijzerman, R.G.3
De Vries, G.4
Stehouwer, C.D.5
-
69
-
-
0029159654
-
Insulin induces translocation of GLUT-4 glucose transporters in human skeletal muscle
-
A Guma JR Zierath H Wallberg-Henriksson A Klip 1995 Insulin induces translocation of GLUT-4 glucose transporters in human skeletal muscle Am J Physiol 268 E613 E622
-
(1995)
Am J Physiol
, vol.268
-
-
Guma, A.1
Zierath, J.R.2
Wallberg-Henriksson, H.3
Klip, A.4
-
70
-
-
0032104120
-
Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance
-
WT Garvey L Maianu JH Zhu G Brechtel-Hook P Wallace AD Baron 1998 Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance J Clin Invest 101 2377 2386
-
(1998)
J Clin Invest
, vol.101
, pp. 2377-2386
-
-
Garvey, W.T.1
Maianu, L.2
Zhu, J.H.3
Brechtel-Hook, G.4
Wallace, P.5
Baron, A.D.6
-
72
-
-
0033761684
-
Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-α
-
JM Youd S Rattigan MG Clark 2000 Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-α Diabetes 49 1904 1909
-
(2000)
Diabetes
, vol.49
, pp. 1904-1909
-
-
Youd, J.M.1
Rattigan, S.2
Clark, M.G.3
-
73
-
-
0036224228
-
Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo
-
LH Clerk S Rattigan MG Clark 2002 Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo Diabetes 51 1138 1145
-
(2002)
Diabetes
, vol.51
, pp. 1138-1145
-
-
Clerk, L.H.1
Rattigan, S.2
Clark, M.G.3
-
74
-
-
0035026559
-
TNF-α inhibits flow and insulin signaling leading to NO production in aortic endothelial cells
-
F Kim B Gallis MA Corson 2001 TNF-α inhibits flow and insulin signaling leading to NO production in aortic endothelial cells Am J Physiol Cell Physiol 280 C1057 C1065
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Kim, F.1
Gallis, B.2
Corson, M.A.3
-
75
-
-
20944436777
-
Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKβ
-
F Kim KA Tysseling J Rice 2005 Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKβ Arterioscler Thromb Vasc Biol 25 989 994
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 989-994
-
-
Kim, F.1
Tysseling, K.A.2
Rice, J.3
-
76
-
-
33644857995
-
Physiological concentrations of insulin induce endothelin-dependent vasoconstriction of skeletal muscle resistance arteries in the presence of tumor necrosis factor-α. Dependence on c-Jun N-terminal kinase
-
EC Eringa CD Stehouwer K Walburg 2006 Physiological concentrations of insulin induce endothelin-dependent vasoconstriction of skeletal muscle resistance arteries in the presence of tumor necrosis factor-α. Dependence on c-Jun N-terminal kinase Arterioscler Thromb Vasc Biol 26 274 280
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 274-280
-
-
Eringa, E.C.1
Stehouwer, C.D.2
Walburg, K.3
-
77
-
-
40949129628
-
Protein kinase C θ activation induces insulin-mediated constriction of muscle resistance arteries
-
W Bakker P Sipkema CD Stehouwer 2008 Protein kinase C θ activation induces insulin-mediated constriction of muscle resistance arteries Diabetes 57 706 713
-
(2008)
Diabetes
, vol.57
, pp. 706-713
-
-
Bakker, W.1
Sipkema, P.2
Stehouwer, C.D.3
-
78
-
-
0034603858
-
Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
-
G Zeng FH Nystrom LV Ravichandran 2000 Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells Circulation 101 1539 1545
-
(2000)
Circulation
, vol.101
, pp. 1539-1545
-
-
Zeng, G.1
Nystrom, F.H.2
Ravichandran, L.V.3
-
80
-
-
0041355277
-
Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis
-
ZY Jiang Z He BL King 2003 Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis J Biol Chem 278 31964 31971
-
(2003)
J Biol Chem
, vol.278
, pp. 31964-31971
-
-
Jiang, Z.Y.1
He, Z.2
King, B.L.3
-
81
-
-
0021907605
-
Receptor-mediated transport of insulin across endothelial cells
-
GL King SM Johnson 1985 Receptor-mediated transport of insulin across endothelial cells Science 227 1583 1586
-
(1985)
Science
, vol.227
, pp. 1583-1586
-
-
King, G.L.1
Johnson, S.M.2
-
82
-
-
0027997787
-
Filipin-sensitive caveolae-mediated transport in endothelium: Reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules
-
JE Schnitzer P Oh E Pinney J Allard 1994 Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules J Cell Biol 127 1217 1232
-
(1994)
J Cell Biol
, vol.127
, pp. 1217-1232
-
-
Schnitzer, J.E.1
Oh, P.2
Pinney, E.3
Allard, J.4
-
83
-
-
0023910658
-
Vascular transport of insulin to rat cardiac muscle. Central role of the capillary endothelium
-
RS Bar M Boes A Sandra 1988 Vascular transport of insulin to rat cardiac muscle. Central role of the capillary endothelium J Clin Invest 81 1225 1233
-
(1988)
J Clin Invest
, vol.81
, pp. 1225-1233
-
-
Bar, R.S.1
Boes, M.2
Sandra, A.3
-
85
-
-
0029871377
-
Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process
-
GM Steil M Ader DM Moore K Rebrin RN Bergman 1996 Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process J Clin Invest 97 1497 1503
-
(1996)
J Clin Invest
, vol.97
, pp. 1497-1503
-
-
Steil, G.M.1
Ader, M.2
Moore, D.M.3
Rebrin, K.4
Bergman, R.N.5
-
86
-
-
0036314289
-
Mode of transcapillary transport of insulin and insulin analog NN304 in dog hindlimb: Evidence for passive diffusion
-
M Hamilton-Wessler M Ader MK Dea 2002 Mode of transcapillary transport of insulin and insulin analog NN304 in dog hindlimb: evidence for passive diffusion Diabetes 51 574 582
-
(2002)
Diabetes
, vol.51
, pp. 574-582
-
-
Hamilton-Wessler, M.1
Ader, M.2
Dea, M.K.3
-
87
-
-
2442711785
-
Insulin-like growth factor i receptors are more abundant than insulin receptors in human micro- and macrovascular endothelial cells
-
SI Chisalita HJ Arnqvist 2004 Insulin-like growth factor I receptors are more abundant than insulin receptors in human micro- and macrovascular endothelial cells Am J Physiol Endocrinol Metab 286 E896 E901
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
-
-
Chisalita, S.I.1
Arnqvist, H.J.2
-
88
-
-
64149088773
-
SiRNA-mediated silencing of caveolin-1 inhibits insulin transport but enhances insulin-stimulated nitric oxide production
-
H Wang AX Wang EJ Barrett 2008 siRNA-mediated silencing of caveolin-1 inhibits insulin transport but enhances insulin-stimulated nitric oxide production Diabetes 57 A383
-
(2008)
Diabetes
, vol.57
, pp. 383
-
-
Wang, H.1
Wang, A.X.2
Barrett, E.J.3
-
89
-
-
0029950908
-
Transport of insulin and albumin by the microvascular endothelium of the rete mirabile
-
M Bendayan EA Rasio 1996 Transport of insulin and albumin by the microvascular endothelium of the rete mirabile J Cell Sci 109 1857 1864
-
(1996)
J Cell Sci
, vol.109
, pp. 1857-1864
-
-
Bendayan, M.1
Rasio, E.A.2
-
90
-
-
0020469577
-
Binding, internalization, and degradation of insulin in vascular endothelial cells
-
N Kaiser I Vlodavsky A Tur-Sinai Z Fuks E Cerasi 1982 Binding, internalization, and degradation of insulin in vascular endothelial cells Diabetes 31 1077 1083
-
(1982)
Diabetes
, vol.31
, pp. 1077-1083
-
-
Kaiser, N.1
Vlodavsky, I.2
Tur-Sinai, A.3
Fuks, Z.4
Cerasi, E.5
-
91
-
-
0030798998
-
Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway
-
C Tiruppathi W Song M Bergenfeldt P Sass AB Malik 1997 Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway J Biol Chem 272 25968 25975
-
(1997)
J Biol Chem
, vol.272
, pp. 25968-25975
-
-
Tiruppathi, C.1
Song, W.2
Bergenfeldt, M.3
Sass, P.4
Malik, A.B.5
-
92
-
-
35348872064
-
Molecular determinants of endothelial transcytosis and their role in endothelial permeability
-
SA Predescu DN Predescu AB Malik 2007 Molecular determinants of endothelial transcytosis and their role in endothelial permeability Am J Physiol Lung Cell Mol Physiol 293 L823 L842
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Predescu, S.A.1
Predescu, D.N.2
Malik, A.B.3
-
93
-
-
0029789432
-
Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells
-
G Zeng MJ Quon 1996 Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells J Clin Invest 98 894 898
-
(1996)
J Clin Invest
, vol.98
, pp. 894-898
-
-
Zeng, G.1
Quon, M.J.2
-
94
-
-
0032719024
-
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
-
ZY Jiang YW Lin A Clemont 1999 Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats J Clin Invest 104 447 457
-
(1999)
J Clin Invest
, vol.104
, pp. 447-457
-
-
Jiang, Z.Y.1
Lin, Y.W.2
Clemont, A.3
-
95
-
-
26844548397
-
Insulin at physiological concentrations selectively activates insulin but not insulin-like growth factor i (IGF-I) or insulin/IGF-I hybrid receptors in endothelial cells
-
G Li EJ Barrett H Wang W Chai Z Liu 2005 Insulin at physiological concentrations selectively activates insulin but not insulin-like growth factor I (IGF-I) or insulin/IGF-I hybrid receptors in endothelial cells Endocrinology 146 4690 4696
-
(2005)
Endocrinology
, vol.146
, pp. 4690-4696
-
-
Li, G.1
Barrett, E.J.2
Wang, H.3
Chai, W.4
Liu, Z.5
-
96
-
-
40949161074
-
Insulin signaling stimulates insulin transport by bovine aortic endothelial cells
-
H Wang AX Wang Z Liu EJ Barrett 2008 Insulin signaling stimulates insulin transport by bovine aortic endothelial cells Diabetes 57 540 547
-
(2008)
Diabetes
, vol.57
, pp. 540-547
-
-
Wang, H.1
Wang, A.X.2
Liu, Z.3
Barrett, E.J.4
-
97
-
-
0038665339
-
The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance
-
D Vicent J Ilany T Kondo 2003 The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance J Clin Invest 111 1373 1380
-
(2003)
J Clin Invest
, vol.111
, pp. 1373-1380
-
-
Vicent, D.1
Ilany, J.2
Kondo, T.3
-
98
-
-
64149104772
-
Insulin signaling in endothelial cells participates in the regulation of skeletal muscle insulin sensitivity
-
T Kubota N Hubota H Kozono 2008 Insulin signaling in endothelial cells participates in the regulation of skeletal muscle insulin sensitivity Diabetes 57 A369
-
(2008)
Diabetes
, vol.57
, pp. 369
-
-
Kubota, T.1
Hubota, N.2
Kozono, H.3
-
99
-
-
0035180072
-
Resistance to acute insulin induced decreases in large artery stiffness accompanies the insulin resistance syndrome
-
J Westerbacka A Seppala-Lindroos H Yki-Jarvinen 2001 Resistance to acute insulin induced decreases in large artery stiffness accompanies the insulin resistance syndrome J Clin Endocrinol Metab 86 5262 5268
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 5262-5268
-
-
Westerbacka, J.1
Seppala-Lindroos, A.2
Yki-Jarvinen, H.3
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