Acute elevations of plasma asymmetric dimethylarginine and impaired endothelial function in response to a high-fat meal in patients with type 2 diabetes

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 20, Issue 9, 2000, Pages 2039-2044

  Fard, Ali ^a   Tuck, Catherine H ^a   Donis, Joshua A ^a   Sciacca, Robert ^a   Di Tullio, Marco R ^a   Wu, Henry D ^a   Bryant, Todd A ^a   Chen, Niem Tzu ^a   Torres Tamayo, Margarita ^a   Ramasamy, Ravichandran ^a   Berglund, Lars ^a   Ginsberg, Henry N ^a   Homma, Shunichi ^a   Cannon, Paul J ^a  

^a Columbia University ^*  (United States)

Author keywords

Asymmetric dimethylarginine; Diabetes mellitus; Nitric oxide; Triglyceridemia; Vasodilation

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; N(G),N(G) DIMETHYLARGININE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ADULT; AGED; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BRACHIAL ARTERY; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; FEMALE; HUMAN; HYPEREMIA; HYPERTRIGLYCERIDEMIA; LIPID DIET; LIPOPROTEIN BLOOD LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL; VASCULAR ENDOTHELIUM; VASODILATATION;

EID: 0033812927     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.20.9.2039     Document Type: Article

References (36)

1. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
2. Association of postprandial triglyceride and retinyl palmitate responses with newly diagnosed exercise-induced myocardial ischemia in middle-aged men and women
3. Atherosclerosis: An inflammatory disease
4. Large coronary arteries in humans are responsive to changing blood flow: An endothelium-dependent mechanism that fails in patients with atherosclerosis
5. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans
6. Impaired endothelium-dependent and independent dilation of forearm resistance arteries in men with diet-treated non-insulin-dependent diabetes: Role of dyslipidemia
7. Impaired nitric oxide-mediated vasodilation in patients with non-insulin dependent diabetes mellitus
8. Forearm nitric oxide balance, vascular relaxation, and glucose metabolism in NIDDM patients
9. Regulation of endothelial nitric oxide synthase mRNA expression by shear stress
10. Cellular and molecular mechanisms of endothelial cell dysfunction
11. Effect of a single high-fat meal on endothelial function in healthy subjects
12. Effect of antioxidant vitamins on transient impairment of endothelium-dependent brachial artery vasoactivity following a single high-fat meal
13. Endothelium-dependent flow mediated vasodilation in the postprandial state in type 2 diabetes mellitus
14. Endogenous dimethylarginine as an inhibitor of nitric oxide synthesis
15. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
16. Synthesis of N(G),N(G)-dimethylarginine by human endothelial cells
17. Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits
18. Asymmetric dimethylarginine (ADMA): A novel risk factor for endothelial dysfunction: Its role in hypercholesterolemia
19. Cholesterol determination in high-density lipoproteins separated by three different methods
20. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge
21. Non-invasive measurement of human endothelium dependent arterial responses: Accuracy and reproducibility
22. Morning attenuation of endothelium-dependent, flow-mediated dilation in healthy young men: Possible connection to morning peak of cardiac events?
23. Effects of an endogenous inhibitor of nitric oxide synthesis on post capillary venules
24. Response of cerebral blood vessels to an endogenous inhibitor of nitric oxide synthase
25. Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease
26. Transient triglyceridemia decreases vascular reactivity in young, healthy men without risk factors for coronary heart disease
27. Regulation of nitric oxide synthesis by dimethyl arginine dimethylaminohydrolase
28. Occurrence of a new enzyme catalyzing the direct conversion of N(G),N(G)-dimethyl-L-arginine to citrulline in rats
29. Identification of two human dimethylarginine dimethylaminohydrolases
30. Novel mechanism for endothelial dysfunction: Dysregulation of dimethylarginine dimethylaminohydrolase
31. Antiatherogenic effects of L-arginine in the hyper-cholesterolemic rabbit
32. Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits
33. 2 does not contribute to impaired endothelium-dependent relaxation
34. L-arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice
35. Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production
36. Endogenous nitric oxide synthase inhibitor: A novel marker of atherosclerosis