메뉴 건너뛰기




Volumn 8, Issue 3, 2013, Pages

The Immediate Early Gene Product EGR1 and Polycomb Group Proteins Interact in Epigenetic Programming during Chondrogenesis

Author keywords

[No Author keywords available]

Indexed keywords

BMI1 PROTEIN; EARLY GROWTH RESPONSE FACTOR 1; HISTONE H3; POLYCOMB GROUP PROTEIN; TRANSCRIPTION FACTOR EZH2;

EID: 84874643048     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058083     Document Type: Article
Times cited : (35)

References (112)
  • 1
    • 35748954326 scopus 로고    scopus 로고
    • Endochondral ossification: How cartilage is converted into bone in the developing skeleton
    • Mackie EJ, Ahmed YA, Tatarczuch L, Chen KS, Mirams M, (2008) Endochondral ossification: How cartilage is converted into bone in the developing skeleton. Int J Biochem Cell Biol 40: 46-62.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 46-62
    • Mackie, E.J.1    Ahmed, Y.A.2    Tatarczuch, L.3    Chen, K.S.4    Mirams, M.5
  • 4
    • 55349109288 scopus 로고    scopus 로고
    • Hypoxic chondrogenic differentiation of human embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality
    • Koay EJ, Athanasiou KA, (2008) Hypoxic chondrogenic differentiation of human embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality. Osteoarthritis Cartilage 16: 1450-1456.
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 1450-1456
    • Koay, E.J.1    Athanasiou, K.A.2
  • 5
    • 42449109564 scopus 로고    scopus 로고
    • Wnt signaling and skeletal development
    • Liu F, Kohlmeier S, Wang CY, (2008) Wnt signaling and skeletal development. Cell Signal 20: 999-1009.
    • (2008) Cell Signal , vol.20 , pp. 999-1009
    • Liu, F.1    Kohlmeier, S.2    Wang, C.Y.3
  • 6
    • 37249015430 scopus 로고    scopus 로고
    • Multiplicity of BMP signaling in skeletal development
    • Wu X, Shi W, Cao X, (2007) Multiplicity of BMP signaling in skeletal development. Ann N Y Acad Sci 1116: 29-49.
    • (2007) Ann N Y Acad Sci , vol.1116 , pp. 29-49
    • Wu, X.1    Shi, W.2    Cao, X.3
  • 7
    • 34347220127 scopus 로고    scopus 로고
    • Insulin-like growth factor-I and fibroblast growth factor, but not growth hormone, affect growth plate chondrocyte proliferation
    • Hutchison MR, Bassett MH, White PC, (2007) Insulin-like growth factor-I and fibroblast growth factor, but not growth hormone, affect growth plate chondrocyte proliferation. Endocrinology 148: 3122-3130.
    • (2007) Endocrinology , vol.148 , pp. 3122-3130
    • Hutchison, M.R.1    Bassett, M.H.2    White, P.C.3
  • 10
    • 80052431167 scopus 로고    scopus 로고
    • Unraveling the transcriptional regulatory machinery in chondrogenesis
    • Akiyama H, Lefebvre V, (2011) Unraveling the transcriptional regulatory machinery in chondrogenesis. J Bone Miner Metab 29: 390-395.
    • (2011) J Bone Miner Metab , vol.29 , pp. 390-395
    • Akiyama, H.1    Lefebvre, V.2
  • 11
    • 34249299791 scopus 로고    scopus 로고
    • The complex language of chromatin regulation during transcription
    • Berger SL, (2007) The complex language of chromatin regulation during transcription. Nature 447: 407-412.
    • (2007) Nature , vol.447 , pp. 407-412
    • Berger, S.L.1
  • 12
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD, (2001) Translating the histone code. Science 293: 1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 13
    • 34047274419 scopus 로고    scopus 로고
    • Global patterns of histone modifications
    • Rando OJ, (2007) Global patterns of histone modifications. Curr Opin Genet Dev 17: 94-99.
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 94-99
    • Rando, O.J.1
  • 14
    • 77956795282 scopus 로고    scopus 로고
    • Talking to chromatin: post-translational modulation of polycomb group function
    • Niessen HE, Demmers JA, Voncken JW, (2009) Talking to chromatin: post-translational modulation of polycomb group function. Epigenetics & Chromatin 2: 10.
    • (2009) Epigenetics & Chromatin , vol.2 , pp. 10
    • Niessen, H.E.1    Demmers, J.A.2    Voncken, J.W.3
  • 15
    • 70349469565 scopus 로고    scopus 로고
    • Mechanisms of Polycomb gene silencing: knowns and unknowns
    • Simon JA, Kingston RE, (2009) Mechanisms of Polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol 10: 697-708.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 697-708
    • Simon, J.A.1    Kingston, R.E.2
  • 16
    • 0031974535 scopus 로고    scopus 로고
    • Functional analysis of mouse Polycomb group genes
    • van Lohuizen M, (1998) Functional analysis of mouse Polycomb group genes. Cell Mol Life Sci 54: 71-79.
    • (1998) Cell Mol Life Sci , vol.54 , pp. 71-79
    • van Lohuizen, M.1
  • 18
    • 40349112981 scopus 로고    scopus 로고
    • JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion
    • Kawamata A, Izu Y, Yokoyama H, Amagasa T, Wagner EF, et al. (2008) JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion. J Cell Biochem 103: 1037-1045.
    • (2008) J Cell Biochem , vol.103 , pp. 1037-1045
    • Kawamata, A.1    Izu, Y.2    Yokoyama, H.3    Amagasa, T.4    Wagner, E.F.5
  • 19
    • 0027241471 scopus 로고
    • Nerve stimulation and denervation induce differential patterns of immediate early gene mRNA expression in skeletal muscle
    • Abu-Shakra SR, Cole AJ, Drachman DB, (1993) Nerve stimulation and denervation induce differential patterns of immediate early gene mRNA expression in skeletal muscle. Brain Res Mol Brain Res 18: 216-220.
    • (1993) Brain Res Mol Brain Res , vol.18 , pp. 216-220
    • Abu-Shakra, S.R.1    Cole, A.J.2    Drachman, D.B.3
  • 20
    • 67349265144 scopus 로고    scopus 로고
    • The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation
    • Boyle KB, Hadaschik D, Virtue S, Cawthorn WP, Ridley SH, et al. (2009) The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation. Cell Death Differ 16: 782-789.
    • (2009) Cell Death Differ , vol.16 , pp. 782-789
    • Boyle, K.B.1    Hadaschik, D.2    Virtue, S.3    Cawthorn, W.P.4    Ridley, S.H.5
  • 21
    • 0026459976 scopus 로고
    • Neurotransmitter-stimulated immediate-early gene responses are organized through differential post-synaptic receptor mechanisms
    • Carter DA, (1992) Neurotransmitter-stimulated immediate-early gene responses are organized through differential post-synaptic receptor mechanisms. Brain Res Mol Brain Res 16: 111-118.
    • (1992) Brain Res Mol Brain Res , vol.16 , pp. 111-118
    • Carter, D.A.1
  • 22
    • 79953154251 scopus 로고    scopus 로고
    • EGR1 and EGR2 involvement in vertebrate tendon differentiation
    • Lejard V, Blais F, Guerquin MJ, Bonnet A, Bonnin MA, et al. (2010) EGR1 and EGR2 involvement in vertebrate tendon differentiation. J Biol Chem 286: 5855-5867.
    • (2010) J Biol Chem , vol.286 , pp. 5855-5867
    • Lejard, V.1    Blais, F.2    Guerquin, M.J.3    Bonnet, A.4    Bonnin, M.A.5
  • 23
    • 0031943222 scopus 로고    scopus 로고
    • Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies
    • Warner LE, Mancias P, Butler IJ, McDonald CM, Keppen L, et al. (1998) Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies. Nat Genet 18: 382-384.
    • (1998) Nat Genet , vol.18 , pp. 382-384
    • Warner, L.E.1    Mancias, P.2    Butler, I.J.3    McDonald, C.M.4    Keppen, L.5
  • 24
    • 80052284891 scopus 로고    scopus 로고
    • Loss of transcription factor early growth response gene 1 results in impaired endochondral bone repair
    • Reumann MK, Strachna O, Yagerman S, Torrecilla D, Kim J, et al. (2011) Loss of transcription factor early growth response gene 1 results in impaired endochondral bone repair. Bone 49: 743-752.
    • (2011) Bone , vol.49 , pp. 743-752
    • Reumann, M.K.1    Strachna, O.2    Yagerman, S.3    Torrecilla, D.4    Kim, J.5
  • 26
    • 33646870495 scopus 로고    scopus 로고
    • Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
    • Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K, (2006) Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 20: 1123-1136.
    • (2006) Genes Dev , vol.20 , pp. 1123-1136
    • Bracken, A.P.1    Dietrich, N.2    Pasini, D.3    Hansen, K.H.4    Helin, K.5
  • 27
    • 84874602341 scopus 로고    scopus 로고
    • MK3 controls Polycomb-target gene expression via negative feedback on ERK Epigenetics & Chromatin: accepted for publication
    • Prickaerts P, Niessen H, Mouchel-Vielh E, Dahlmans V, van den Akker GGH, et al. (2012) MK3 controls Polycomb-target gene expression via negative feedback on ERK Epigenetics & Chromatin: accepted for publication.
    • (2012)
    • Prickaerts, P.1    Niessen, H.2    Mouchel-Vielh, E.3    Dahlmans, V.4    van den Akker, G.G.H.5
  • 28
    • 0025338661 scopus 로고
    • A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells
    • Atsumi T, Miwa Y, Kimata K, Ikawa Y, (1990) A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells. Cell Differ Dev 30: 109-116.
    • (1990) Cell Differ Dev , vol.30 , pp. 109-116
    • Atsumi, T.1    Miwa, Y.2    Kimata, K.3    Ikawa, Y.4
  • 29
    • 0033178337 scopus 로고    scopus 로고
    • p38 Mitogen-Activated Protein Kinase Functionally Contributes to Chondrogenesis Induced by Growth/Differentiation Factor-5 in ATDC5 Cells
    • Nakamura K, Shirai T, Morishita S, Uchida S, Saeki-Miura K, et al. (1999) p38 Mitogen-Activated Protein Kinase Functionally Contributes to Chondrogenesis Induced by Growth/Differentiation Factor-5 in ATDC5 Cells. Experimental Cell Research 250: 351-363.
    • (1999) Experimental Cell Research , vol.250 , pp. 351-363
    • Nakamura, K.1    Shirai, T.2    Morishita, S.3    Uchida, S.4    Saeki-Miura, K.5
  • 30
    • 33646847035 scopus 로고    scopus 로고
    • Temporal transcriptome of mouse ATDC5 chondroprogenitors differentiating under hypoxic conditions
    • Chen L, Fink T, Ebbesen P, Zachar V, (2006) Temporal transcriptome of mouse ATDC5 chondroprogenitors differentiating under hypoxic conditions. Exp Cell Res.
    • (2006) Exp Cell Res
    • Chen, L.1    Fink, T.2    Ebbesen, P.3    Zachar, V.4
  • 31
    • 0344688180 scopus 로고    scopus 로고
    • Transcriptome analysis of early chondrogenesis in ATDC5 cells induced by bone morphogenetic protein 4
    • Wahl M, Shukunami C, Heinzmann U, Hamajima K, Hiraki Y, et al. (2004) Transcriptome analysis of early chondrogenesis in ATDC5 cells induced by bone morphogenetic protein 4. Genomics 83: 45-58.
    • (2004) Genomics , vol.83 , pp. 45-58
    • Wahl, M.1    Shukunami, C.2    Heinzmann, U.3    Hamajima, K.4    Hiraki, Y.5
  • 32
    • 0032718990 scopus 로고    scopus 로고
    • Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation
    • Fujii M, Takeda K, Imamura T, Aoki H, Sampath TK, et al. (1999) Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation. Mol Biol Cell 10: 3801-3813.
    • (1999) Mol Biol Cell , vol.10 , pp. 3801-3813
    • Fujii, M.1    Takeda, K.2    Imamura, T.3    Aoki, H.4    Sampath, T.K.5
  • 33
    • 0029875398 scopus 로고    scopus 로고
    • Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor
    • Shukunami C, Shigeno C, Atsumi T, Ishizeki K, Suzuki F, et al. (1996) Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor. J Cell Biol 133: 457-468.
    • (1996) J Cell Biol , vol.133 , pp. 457-468
    • Shukunami, C.1    Shigeno, C.2    Atsumi, T.3    Ishizeki, K.4    Suzuki, F.5
  • 34
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
    • Akiyama H, Chaboissier MC, Martin JF, Schedl A, de Crombrugghe B, (2002) The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev 16: 2813-2828.
    • (2002) Genes Dev , vol.16 , pp. 2813-2828
    • Akiyama, H.1    Chaboissier, M.C.2    Martin, J.F.3    Schedl, A.4    de Crombrugghe, B.5
  • 36
    • 20044364559 scopus 로고    scopus 로고
    • Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development
    • Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, et al. (2005) Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol 203: 133-143.
    • (2005) J Cell Physiol , vol.203 , pp. 133-143
    • Smith, N.1    Dong, Y.2    Lian, J.B.3    Pratap, J.4    Kingsley, P.D.5
  • 37
    • 0036569779 scopus 로고    scopus 로고
    • Role of Runx genes in chondrocyte differentiation
    • Stricker S, Fundele R, Vortkamp A, Mundlos S, (2002) Role of Runx genes in chondrocyte differentiation. Dev Biol 245: 95-108.
    • (2002) Dev Biol , vol.245 , pp. 95-108
    • Stricker, S.1    Fundele, R.2    Vortkamp, A.3    Mundlos, S.4
  • 38
    • 84858021975 scopus 로고    scopus 로고
    • Activation of NF-kappaB/p65 facilitates early chondrogenic differentiation during endochondral ossification
    • Caron MM, Emans PJ, Surtel DA, Cremers A, Voncken JW, et al. (2012) Activation of NF-kappaB/p65 facilitates early chondrogenic differentiation during endochondral ossification. PLoS One 7: e33467.
    • (2012) PLoS One , vol.7
    • Caron, M.M.1    Emans, P.J.2    Surtel, D.A.3    Cremers, A.4    Voncken, J.W.5
  • 39
    • 3042618657 scopus 로고    scopus 로고
    • Developmental biology. Hox genes in the limb: a play in two acts
    • Deschamps J, (2004) Developmental biology. Hox genes in the limb: a play in two acts. Science 304: 1610-1611.
    • (2004) Science , vol.304 , pp. 1610-1611
    • Deschamps, J.1
  • 40
    • 0033375380 scopus 로고    scopus 로고
    • Initiation, establishment and maintenance of Hox gene expression patterns in the mouse
    • Deschamps J, van den Akker E, Forlani S, De Graaff W, Oosterveen T, et al. (1999) Initiation, establishment and maintenance of Hox gene expression patterns in the mouse. Int J Dev Biol 43: 635-650.
    • (1999) Int J Dev Biol , vol.43 , pp. 635-650
    • Deschamps, J.1    van den Akker, E.2    Forlani, S.3    De Graaff, W.4    Oosterveen, T.5
  • 41
    • 0027932522 scopus 로고
    • Colinearity and functional hierarchy among genes of the homeotic complexes
    • Duboule D, Morata G, (1994) Colinearity and functional hierarchy among genes of the homeotic complexes. Trends Genet 10: 358-364.
    • (1994) Trends Genet , vol.10 , pp. 358-364
    • Duboule, D.1    Morata, G.2
  • 42
    • 66749180667 scopus 로고    scopus 로고
    • Epigenetic temporal control of mouse Hox genes in vivo
    • Soshnikova N, Duboule D, (2009) Epigenetic temporal control of mouse Hox genes in vivo. Science 324: 1320-1323.
    • (2009) Science , vol.324 , pp. 1320-1323
    • Soshnikova, N.1    Duboule, D.2
  • 43
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R, (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science 296: 550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 44
    • 0042887424 scopus 로고    scopus 로고
    • Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte-specific expression in vivo
    • Zheng Q, Zhou G, Morello R, Chen Y, Garcia-Rojas X, et al. (2003) Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte-specific expression in vivo. J Cell Biol 162: 833-842.
    • (2003) J Cell Biol , vol.162 , pp. 833-842
    • Zheng, Q.1    Zhou, G.2    Morello, R.3    Chen, Y.4    Garcia-Rojas, X.5
  • 45
    • 0037089626 scopus 로고    scopus 로고
    • SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
    • Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ III, (2002) SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev 16: 919-932.
    • (2002) Genes Dev , vol.16 , pp. 919-932
    • Schultz, D.C.1    Ayyanathan, K.2    Negorev, D.3    Maul, G.G.4    Rauscher III, F.J.5
  • 46
    • 0033013868 scopus 로고    scopus 로고
    • KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing
    • Ryan RF, Schultz DC, Ayyanathan K, Singh PB, Friedman JR, et al. (1999) KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing. Mol Cell Biol 19: 4366-4378.
    • (1999) Mol Cell Biol , vol.19 , pp. 4366-4378
    • Ryan, R.F.1    Schultz, D.C.2    Ayyanathan, K.3    Singh, P.B.4    Friedman, J.R.5
  • 47
    • 0035160307 scopus 로고    scopus 로고
    • Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1beta
    • Vincenti MP, Brinckerhoff CE, (2001) Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1beta. Arthritis Res 3: 381-388.
    • (2001) Arthritis Res , vol.3 , pp. 381-388
    • Vincenti, M.P.1    Brinckerhoff, C.E.2
  • 48
    • 60949089801 scopus 로고    scopus 로고
    • Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by tumour necrosis factor-alpha-induced MEK/ERK signalling
    • Rockel JS, Bernier SM, Leask A, (2009) Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by tumour necrosis factor-alpha-induced MEK/ERK signalling. Arthritis Res Ther 11: R8.
    • (2009) Arthritis Res Ther , vol.11
    • Rockel, J.S.1    Bernier, S.M.2    Leask, A.3
  • 49
    • 65549146911 scopus 로고    scopus 로고
    • E2F1 Induces Tumor Cell Survival via Nuclear Factor-kappa b Dependent Induction of EGR1 Transcription in Prostate Cancer Cells
    • Zheng C, Ren Z, Wang H, Zhang W, Kalvakolanu DV, et al. (2009) E2F1 Induces Tumor Cell Survival via Nuclear Factor-kappa b Dependent Induction of EGR1 Transcription in Prostate Cancer Cells. Cancer Research 69: 2324-2331.
    • (2009) Cancer Research , vol.69 , pp. 2324-2331
    • Zheng, C.1    Ren, Z.2    Wang, H.3    Zhang, W.4    Kalvakolanu, D.V.5
  • 50
    • 71749111154 scopus 로고    scopus 로고
    • Targeted Knockdown of EGR-1 Inhibits IL-8 Production and IL-8-mediated Invasion of Prostate Cancer Cells through Suppressing EGR-1/NF-κB Synergy
    • Ma J, Ren Z, Ma Y, Xu L, Zhao Y, et al. (2009) Targeted Knockdown of EGR-1 Inhibits IL-8 Production and IL-8-mediated Invasion of Prostate Cancer Cells through Suppressing EGR-1/NF-κB Synergy. Journal of Biological Chemistry 284: 34600-34606.
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 34600-34606
    • Ma, J.1    Ren, Z.2    Ma, Y.3    Xu, L.4    Zhao, Y.5
  • 51
    • 77951183754 scopus 로고    scopus 로고
    • Transcription factor Egr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor alpha
    • Shin SY, Kim JH, Baker A, Lim Y, Lee YH, (2010) Transcription factor Egr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor alpha. Mol Cancer Res 8: 507-519.
    • (2010) Mol Cancer Res , vol.8 , pp. 507-519
    • Shin, S.Y.1    Kim, J.H.2    Baker, A.3    Lim, Y.4    Lee, Y.H.5
  • 52
    • 84859450254 scopus 로고    scopus 로고
    • Regulation of human microsomal prostaglandin E synthase-1 by IL-1beta requires a distal enhancer element with a unique role for C/EBPbeta
    • Walters JN, Bickford JS, Newsom KJ, Beachy DE, Barilovits SJ, et al. (2012) Regulation of human microsomal prostaglandin E synthase-1 by IL-1beta requires a distal enhancer element with a unique role for C/EBPbeta. Biochem J 443: 561-571.
    • (2012) Biochem J , vol.443 , pp. 561-571
    • Walters, J.N.1    Bickford, J.S.2    Newsom, K.J.3    Beachy, D.E.4    Barilovits, S.J.5
  • 53
    • 0034124587 scopus 로고    scopus 로고
    • Differential expression of egr-1 in osteoarthritic compared to normal adult human articular cartilage
    • Wang FL, Connor JR, Dodds RA, James IE, Kumar S, et al. (2000) Differential expression of egr-1 in osteoarthritic compared to normal adult human articular cartilage. Osteoarthritis Cartilage 8: 161-169.
    • (2000) Osteoarthritis Cartilage , vol.8 , pp. 161-169
    • Wang, F.L.1    Connor, J.R.2    Dodds, R.A.3    James, I.E.4    Kumar, S.5
  • 54
    • 84858966476 scopus 로고    scopus 로고
    • Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor gamma expression in human osteoarthritic chondrocytes
    • Nebbaki SS, El Mansouri FE, Afif H, Kapoor M, Benderdour M, et al. (2012) Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor gamma expression in human osteoarthritic chondrocytes. Arthritis Res Ther 14: R69.
    • (2012) Arthritis Res Ther , vol.14
    • Nebbaki, S.S.1    El Mansouri, F.E.2    Afif, H.3    Kapoor, M.4    Benderdour, M.5
  • 55
    • 84857980948 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 impacts chondrocyte hypertrophic differentiation during endochondral ossification
    • Welting TJ, Caron MM, Emans PJ, Janssen MP, Sanen K, et al. (2011) Inhibition of cyclooxygenase-2 impacts chondrocyte hypertrophic differentiation during endochondral ossification. Eur Cell Mater 22: 420-436 discussion 436-427.
    • (2011) Eur Cell Mater , vol.22 , pp. 420-436
    • Welting, T.J.1    Caron, M.M.2    Emans, P.J.3    Janssen, M.P.4    Sanen, K.5
  • 56
    • 34548644772 scopus 로고    scopus 로고
    • The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
    • De Santa F, Totaro MG, Prosperini E, Notarbartolo S, Testa G, et al. (2007) The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 130: 1083-1094.
    • (2007) Cell , vol.130 , pp. 1083-1094
    • De Santa, F.1    Totaro, M.G.2    Prosperini, E.3    Notarbartolo, S.4    Testa, G.5
  • 57
    • 70349759093 scopus 로고    scopus 로고
    • Induction of early growth response-1 mediates microglia activation in vitro but is dispensable in vivo
    • Langmann T, Ebert S, Walczak Y, Weigelt K, Ehrengruber MU, et al. (2009) Induction of early growth response-1 mediates microglia activation in vitro but is dispensable in vivo. Neuromolecular Med 11: 87-96.
    • (2009) Neuromolecular Med , vol.11 , pp. 87-96
    • Langmann, T.1    Ebert, S.2    Walczak, Y.3    Weigelt, K.4    Ehrengruber, M.U.5
  • 58
    • 0034981923 scopus 로고    scopus 로고
    • EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression
    • Nagarajan R, Svaren J, Le N, Araki T, Watson M, et al. (2001) EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression. Neuron 30: 355-368.
    • (2001) Neuron , vol.30 , pp. 355-368
    • Nagarajan, R.1    Svaren, J.2    Le, N.3    Araki, T.4    Watson, M.5
  • 59
    • 42249085983 scopus 로고    scopus 로고
    • Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3
    • Collins S, Lutz MA, Zarek PE, Anders RA, Kersh GJ, et al. (2008) Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3. Eur J Immunol 38: 528-536.
    • (2008) Eur J Immunol , vol.38 , pp. 528-536
    • Collins, S.1    Lutz, M.A.2    Zarek, P.E.3    Anders, R.A.4    Kersh, G.J.5
  • 60
    • 58249118862 scopus 로고    scopus 로고
    • Transcription factors in long-term memory and synaptic plasticity
    • Alberini CM, (2009) Transcription factors in long-term memory and synaptic plasticity. Physiol Rev 89: 121-145.
    • (2009) Physiol Rev , vol.89 , pp. 121-145
    • Alberini, C.M.1
  • 61
  • 62
    • 33847388338 scopus 로고    scopus 로고
    • Early growth response transcriptional regulators are dispensable for macrophage differentiation
    • Carter JH, Tourtellotte WG, (2007) Early growth response transcriptional regulators are dispensable for macrophage differentiation. J Immunol 178: 3038-3047.
    • (2007) J Immunol , vol.178 , pp. 3038-3047
    • Carter, J.H.1    Tourtellotte, W.G.2
  • 63
    • 0028940050 scopus 로고
    • Growth and differentiation proceeds normally in cells deficient in the immediate early gene NGFI-A
    • Lee SL, Tourtellotte LC, Wesselschmidt RL, Milbrandt J, (1995) Growth and differentiation proceeds normally in cells deficient in the immediate early gene NGFI-A. J Biol Chem 270: 9971-9977.
    • (1995) J Biol Chem , vol.270 , pp. 9971-9977
    • Lee, S.L.1    Tourtellotte, L.C.2    Wesselschmidt, R.L.3    Milbrandt, J.4
  • 64
    • 11844294603 scopus 로고    scopus 로고
    • Molecular and immunohistological characterization of human cartilage two years following autologous cell transplantation
    • Grigolo B, Roseti L, De Franceschi L, Piacentini A, Cattini L, et al. (2005) Molecular and immunohistological characterization of human cartilage two years following autologous cell transplantation. J Bone Joint Surg Am 87: 46-57.
    • (2005) J Bone Joint Surg Am , vol.87 , pp. 46-57
    • Grigolo, B.1    Roseti, L.2    De Franceschi, L.3    Piacentini, A.4    Cattini, L.5
  • 65
    • 84861216606 scopus 로고    scopus 로고
    • Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes
    • Bougault C, Aubert-Foucher E, Paumier A, Perrier-Groult E, Huot L, et al. (2012) Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes. PLoS One 7: e36964.
    • (2012) PLoS One , vol.7
    • Bougault, C.1    Aubert-Foucher, E.2    Paumier, A.3    Perrier-Groult, E.4    Huot, L.5
  • 66
    • 33845269825 scopus 로고    scopus 로고
    • Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
    • Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, et al. (2006) Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444: 638-642.
    • (2006) Nature , vol.444 , pp. 638-642
    • Di Micco, R.1    Fumagalli, M.2    Cicalese, A.3    Piccinin, S.4    Gasparini, P.5
  • 67
    • 80052868490 scopus 로고    scopus 로고
    • Early growth response 1-a transcription factor in the crossfire of signal transduction cascades
    • Pagel JI, Deindl E, (2011) Early growth response 1-a transcription factor in the crossfire of signal transduction cascades. Indian J Biochem Biophys 48: 226-235.
    • (2011) Indian J Biochem Biophys , vol.48 , pp. 226-235
    • Pagel, J.I.1    Deindl, E.2
  • 68
    • 35648995976 scopus 로고    scopus 로고
    • Interleukin-6 and its receptor in cancer: implications for Translational Therapeutics
    • Hong DS, Angelo LS, Kurzrock R, (2007) Interleukin-6 and its receptor in cancer: implications for Translational Therapeutics. Cancer 110: 1911-1928.
    • (2007) Cancer , vol.110 , pp. 1911-1928
    • Hong, D.S.1    Angelo, L.S.2    Kurzrock, R.3
  • 69
    • 44649101304 scopus 로고    scopus 로고
    • Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
    • Kuilman T, Michaloglou C, Vredeveld LC, Douma S, van Doorn R, et al. (2008) Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 133: 1019-1031.
    • (2008) Cell , vol.133 , pp. 1019-1031
    • Kuilman, T.1    Michaloglou, C.2    Vredeveld, L.C.3    Douma, S.4    van Doorn, R.5
  • 70
    • 0032533875 scopus 로고    scopus 로고
    • cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1)
    • Silverman ES, Du J, Williams AJ, Wadgaonkar R, Drazen JM, et al. (1998) cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1). Biochem J 336 (Pt 1):: 183-189.
    • (1998) Biochem J , vol.336 , Issue.Pt 1 , pp. 183-189
    • Silverman, E.S.1    Du, J.2    Williams, A.J.3    Wadgaonkar, R.4    Drazen, J.M.5
  • 71
    • 3042801241 scopus 로고    scopus 로고
    • Coactivating Factors p300 and CBP Are Transcriptionally Crossregulated by Egr1 in Prostate Cells, Leading to Divergent Responses
    • Yu J, de Belle I, Liang H, Adamson ED, (2004) Coactivating Factors p300 and CBP Are Transcriptionally Crossregulated by Egr1 in Prostate Cells, Leading to Divergent Responses. Molecular Cell 15: 83-94.
    • (2004) Molecular Cell , vol.15 , pp. 83-94
    • Yu, J.1    de Belle, I.2    Liang, H.3    Adamson, E.D.4
  • 72
    • 33847093463 scopus 로고    scopus 로고
    • The Transcription Factor Nerve Growth Factor-Inducible Protein A Mediates Epigenetic Programming: Altering Epigenetic Marks by Immediate-Early Genes
    • Weaver ICG, D'Alessio AC, Brown SE, Hellstrom IC, Dymov S, et al. (2007) The Transcription Factor Nerve Growth Factor-Inducible Protein A Mediates Epigenetic Programming: Altering Epigenetic Marks by Immediate-Early Genes. J Neurosci 27: 1756-1768.
    • (2007) J Neurosci , vol.27 , pp. 1756-1768
    • Weaver, I.C.G.1    D'Alessio, A.C.2    Brown, S.E.3    Hellstrom, I.C.4    Dymov, S.5
  • 75
    • 84867010006 scopus 로고    scopus 로고
    • c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
    • Nie Z, Hu G, Wei G, Cui K, Yamane A, et al. (2012) c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells. Cell 151: 68-79.
    • (2012) Cell , vol.151 , pp. 68-79
    • Nie, Z.1    Hu, G.2    Wei, G.3    Cui, K.4    Yamane, A.5
  • 76
    • 33744955345 scopus 로고    scopus 로고
    • NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex
    • Srinivasan R, Mager GM, Ward RM, Mayer J, Svaren J, (2006) NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex. J Biol Chem 281: 15129-15137.
    • (2006) J Biol Chem , vol.281 , pp. 15129-15137
    • Srinivasan, R.1    Mager, G.M.2    Ward, R.M.3    Mayer, J.4    Svaren, J.5
  • 77
    • 0029891229 scopus 로고    scopus 로고
    • NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli
    • Svaren J, Sevetson BR, Apel ED, Zimonjic DB, Popescu NC, et al. (1996) NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. Mol Cell Biol 16: 3545-3553.
    • (1996) Mol Cell Biol , vol.16 , pp. 3545-3553
    • Svaren, J.1    Sevetson, B.R.2    Apel, E.D.3    Zimonjic, D.B.4    Popescu, N.C.5
  • 78
    • 0034597331 scopus 로고    scopus 로고
    • The human transcriptional repressor protein NAB1: expression and biological activity
    • Thiel G, Kaufmann K, Magin A, Lietz M, Bach K, et al. (2000) The human transcriptional repressor protein NAB1: expression and biological activity. Biochim Biophys Acta 1493: 289-301.
    • (2000) Biochim Biophys Acta , vol.1493 , pp. 289-301
    • Thiel, G.1    Kaufmann, K.2    Magin, A.3    Lietz, M.4    Bach, K.5
  • 79
    • 0037315381 scopus 로고    scopus 로고
    • Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression
    • Decker EL, Nehmann N, Kampen E, Eibel H, Zipfel PF, et al. (2003) Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression. Nucleic Acids Res 31: 911-921.
    • (2003) Nucleic Acids Res , vol.31 , pp. 911-921
    • Decker, E.L.1    Nehmann, N.2    Kampen, E.3    Eibel, H.4    Zipfel, P.F.5
  • 80
    • 0038381435 scopus 로고    scopus 로고
    • Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta
    • Tan L, Peng H, Osaki M, Choy BK, Auron PE, et al. (2003) Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta. J Biol Chem 278: 17688-17700.
    • (2003) J Biol Chem , vol.278 , pp. 17688-17700
    • Tan, L.1    Peng, H.2    Osaki, M.3    Choy, B.K.4    Auron, P.E.5
  • 81
    • 0030445119 scopus 로고    scopus 로고
    • A Krox binding site regulates protease nexin-1 promoter activity in embryonic heart, cartilage and parts of the nervous system
    • Erno H, Kury P, Botteri FM, Monard D, (1996) A Krox binding site regulates protease nexin-1 promoter activity in embryonic heart, cartilage and parts of the nervous system. Mech Dev 60: 139-150.
    • (1996) Mech Dev , vol.60 , pp. 139-150
    • Erno, H.1    Kury, P.2    Botteri, F.M.3    Monard, D.4
  • 82
    • 0037111831 scopus 로고    scopus 로고
    • Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
    • Kuzmichev A, Nishioka K, Erdjument-Bromage H, Tempst P, Reinberg D, (2002) Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev 16: 2893-2905.
    • (2002) Genes Dev , vol.16 , pp. 2893-2905
    • Kuzmichev, A.1    Nishioka, K.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 83
    • 1942503942 scopus 로고    scopus 로고
    • The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3
    • Cao R, Zhang Y, (2004) The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr Opin Genet Dev 14: 155-164.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 155-164
    • Cao, R.1    Zhang, Y.2
  • 84
    • 0032516241 scopus 로고    scopus 로고
    • The Bmi-1 oncoprotein interacts with dinG and MPh2: the role of RING finger domains
    • Hemenway CS, Halligan BW, Levy LS, (1998) The Bmi-1 oncoprotein interacts with dinG and MPh2: the role of RING finger domains. Oncogene 16: 2541-2547.
    • (1998) Oncogene , vol.16 , pp. 2541-2547
    • Hemenway, C.S.1    Halligan, B.W.2    Levy, L.S.3
  • 85
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • Bracken AP, Pasini D, Capra M, Prosperini E, Colli E, et al. (2003) EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. Embo J 22: 5323-5335.
    • (2003) Embo J , vol.22 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5
  • 86
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M, (1999) The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397: 164-168.
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    van Lohuizen, M.5
  • 88
    • 29144521539 scopus 로고    scopus 로고
    • Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila
    • Goodliffe JM, Wieschaus E, Cole MD, (2005) Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila. Genes Dev 19: 2941-2946.
    • (2005) Genes Dev , vol.19 , pp. 2941-2946
    • Goodliffe, J.M.1    Wieschaus, E.2    Cole, M.D.3
  • 89
    • 33947134834 scopus 로고    scopus 로고
    • The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
    • Bracken AP, Kleine-Kohlbrecher D, Dietrich N, Pasini D, Gargiulo G, et al. (2007) The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Genes Dev 21: 525-530.
    • (2007) Genes Dev , vol.21 , pp. 525-530
    • Bracken, A.P.1    Kleine-Kohlbrecher, D.2    Dietrich, N.3    Pasini, D.4    Gargiulo, G.5
  • 90
    • 0037667702 scopus 로고    scopus 로고
    • Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
    • Narita M, Nunez S, Heard E, Lin AW, Hearn SA, et al. (2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113: 703-716.
    • (2003) Cell , vol.113 , pp. 703-716
    • Narita, M.1    Nunez, S.2    Heard, E.3    Lin, A.W.4    Hearn, S.A.5
  • 91
    • 33845755946 scopus 로고    scopus 로고
    • Heterochromatin revisited
    • Grewal SI, Jia S, (2007) Heterochromatin revisited. Nat Rev Genet 8: 35-46.
    • (2007) Nat Rev Genet , vol.8 , pp. 35-46
    • Grewal, S.I.1    Jia, S.2
  • 92
    • 79960055393 scopus 로고    scopus 로고
    • KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response
    • Goodarzi AA, Kurka T, Jeggo PA, (2011) KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. Nat Struct Mol Biol 18: 831-839.
    • (2011) Nat Struct Mol Biol , vol.18 , pp. 831-839
    • Goodarzi, A.A.1    Kurka, T.2    Jeggo, P.A.3
  • 93
    • 47349107760 scopus 로고    scopus 로고
    • ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin
    • Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, et al. (2008) ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin. Molecular Cell 31: 167-177.
    • (2008) Molecular Cell , vol.31 , pp. 167-177
    • Goodarzi, A.A.1    Noon, A.T.2    Deckbar, D.3    Ziv, Y.4    Shiloh, Y.5
  • 94
    • 68249096784 scopus 로고    scopus 로고
    • Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
    • Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, et al. (2009) Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol.
    • (2009) Nat Cell Biol
    • Rodier, F.1    Coppe, J.P.2    Patil, C.K.3    Hoeijmakers, W.A.4    Munoz, D.P.5
  • 95
    • 37249041657 scopus 로고    scopus 로고
    • RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination
    • Matthews AG, Kuo AJ, Ramon-Maiques S, Han S, Champagne KS, et al. (2007) RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature 450: 1106-1110.
    • (2007) Nature , vol.450 , pp. 1106-1110
    • Matthews, A.G.1    Kuo, A.J.2    Ramon-Maiques, S.3    Han, S.4    Champagne, K.S.5
  • 96
    • 33745868054 scopus 로고    scopus 로고
    • ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression
    • Shi X, Hong T, Walter KL, Ewalt M, Michishita E, et al. (2006) ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature 442: 96-99.
    • (2006) Nature , vol.442 , pp. 96-99
    • Shi, X.1    Hong, T.2    Walter, K.L.3    Ewalt, M.4    Michishita, E.5
  • 97
    • 84864310537 scopus 로고    scopus 로고
    • Replicating and transcribing on twisted roads of chromatin
    • Giri S, Prasanth SG, (2012) Replicating and transcribing on twisted roads of chromatin. Brief Funct Genomics 11: 188-204.
    • (2012) Brief Funct Genomics , vol.11 , pp. 188-204
    • Giri, S.1    Prasanth, S.G.2
  • 99
    • 55749101777 scopus 로고    scopus 로고
    • Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
    • Nielsen R, Pedersen TA, Hagenbeek D, Moulos P, Siersbaek R, et al. (2008) Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes Dev 22: 2953-2967.
    • (2008) Genes Dev , vol.22 , pp. 2953-2967
    • Nielsen, R.1    Pedersen, T.A.2    Hagenbeek, D.3    Moulos, P.4    Siersbaek, R.5
  • 101
    • 0029833422 scopus 로고    scopus 로고
    • Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
    • Kinsella TM, Nolan GP, (1996) Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. HumGene Ther 7: 1405-1413.
    • (1996) HumGene Ther , vol.7 , pp. 1405-1413
    • Kinsella, T.M.1    Nolan, G.P.2
  • 102
    • 0025352187 scopus 로고
    • Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
    • Morgenstern JP, Land H, (1990) Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res 18: 3587-3596.
    • (1990) Nucleic Acids Res , vol.18 , pp. 3587-3596
    • Morgenstern, J.P.1    Land, H.2
  • 103
    • 33846128155 scopus 로고    scopus 로고
    • The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence
    • Mallette FA, Gaumont-Leclerc MF, Ferbeyre G, (2007) The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. Genes Dev 21: 43-48.
    • (2007) Genes Dev , vol.21 , pp. 43-48
    • Mallette, F.A.1    Gaumont-Leclerc, M.F.2    Ferbeyre, G.3
  • 104
    • 0025317094 scopus 로고
    • Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals
    • Cao XM, Koski RA, Gashler A, McKiernan M, Morris CF, et al. (1990) Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals. Mol Cell Biol 10: 1931-1939.
    • (1990) Mol Cell Biol , vol.10 , pp. 1931-1939
    • Cao, X.M.1    Koski, R.A.2    Gashler, A.3    McKiernan, M.4    Morris, C.F.5
  • 105
    • 0029161198 scopus 로고
    • Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors
    • Gashler A, Sukhatme VP, (1995) Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors. Prog Nucleic Acid Res Mol Biol 50: 191-224.
    • (1995) Prog Nucleic Acid Res Mol Biol , vol.50 , pp. 191-224
    • Gashler, A.1    Sukhatme, V.P.2
  • 106
    • 0028900074 scopus 로고
    • DNA-binding specificity of NGFI-A and related zinc finger transcription factors
    • Swirnoff AH, Milbrandt J, (1995) DNA-binding specificity of NGFI-A and related zinc finger transcription factors. Mol Cell Biol 15: 2275-2287.
    • (1995) Mol Cell Biol , vol.15 , pp. 2275-2287
    • Swirnoff, A.H.1    Milbrandt, J.2
  • 109
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: open software development for computational biology and bioinformatics
    • Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al. (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80.
    • (2004) Genome Biol , vol.5
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3    Bolstad, B.4    Dettling, M.5
  • 111
    • 29144535372 scopus 로고    scopus 로고
    • Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
    • Dai M, Wang P, Boyd AD, Kostov G, Athey B, et al. (2005) Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res 33: e175.
    • (2005) Nucleic Acids Res , vol.33
    • Dai, M.1    Wang, P.2    Boyd, A.D.3    Kostov, G.4    Athey, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.