Regulation of human microsomal prostaglandin E synthase-1 by IL-1β requires a distal enhancer element with a unique role for C/EBPβ

Biochemical Journal

Volumn 443, Issue 2, 2012, Pages 561-571

  Walters, Jewell N ^a   Bickford, Justin S ^a,b   Newsom, Kimberly J ^a,b   Beachy, Dawn E ^b   Barilovits, Sarah J ^a   Herlihy, John David ^b   Nick, Harry S ^a,b  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

CCAAT enhancer binding protein (C EBP ); DNase I hypersensitive site; Early growth response protein 1 (Egr 1); Gene regulation; Microsomal prostaglandin E synthase 1 (mPGES 1)

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; DEOXYRIBONUCLEASE I; INTERLEUKIN 1BETA; PROSTAGLANDIN E SYNTHASE 1; RNA POLYMERASE II;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENHANCER REGION; ENZYME REGULATION; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; KNOCKOUT GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ANIMALS; BASE SEQUENCE; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELLS, CULTURED; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTERLEUKIN-1BETA; INTRAMOLECULAR OXIDOREDUCTASES; MICE; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; RATS; RNA POLYMERASE II; RNA, MESSENGER;

EID: 84859450254     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111801     Document Type: Article

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