메뉴 건너뛰기




Volumn 64, Issue 4, 2005, Pages 157-165

Endocrine regulation of the growth plate

Author keywords

Androgen; Estrogen; Glucocorticoid; Growth hormone; Growth plate; Hormones; Insulin like growth factor; Leptin; Longitudinal bone growth; Thyroid hormone; Vitamin D

Indexed keywords

ANDROGEN; ESTROGEN; GLUCOCORTICOID; GROWTH HORMONE; LEPTIN; THYROID HORMONE; VITAMIN D;

EID: 27844501170     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000088791     Document Type: Short Survey
Times cited : (356)

References (89)
  • 1
    • 0015057014 scopus 로고
    • Cell population kinetics of bone growth: The first ten years of autoradiographic studies with tritiated thymidine
    • Kember NF: Cell population kinetics of bone growth: the first ten years of autoradiographic studies with tritiated thymidine. Clin Orthop 1971;76:213-230.
    • (1971) Clin Orthop , vol.76 , pp. 213-230
    • Kember, N.F.1
  • 3
    • 0028067659 scopus 로고
    • Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes
    • Hunziker EB: Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes. Microsc Res Tech 1994;28:505-519.
    • (1994) Microsc Res Tech , vol.28 , pp. 505-519
    • Hunziker, E.B.1
  • 4
    • 0033027858 scopus 로고    scopus 로고
    • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
    • Gerber HP, Vu TH, Ryan AM, Kowalski J, Werb Z, Ferrara N: VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 1999;5:623-628.
    • (1999) Nat Med , vol.5 , pp. 623-628
    • Gerber, H.P.1    Vu, T.H.2    Ryan, A.M.3    Kowalski, J.4    Werb, Z.5    Ferrara, N.6
  • 5
    • 0024361393 scopus 로고
    • Cellular turnover at the chondro-osseous junction of growth plate cartilage: Analysis by serial sections at the light microscopical level
    • Farnum CE, Wilsman NJ: Cellular turnover at the chondro-osseous junction of growth plate cartilage: analysis by serial sections at the light microscopical level. J Orthop Res 1989;7:654-666.
    • (1989) J Orthop Res , vol.7 , pp. 654-666
    • Farnum, C.E.1    Wilsman, N.J.2
  • 6
    • 0032908103 scopus 로고    scopus 로고
    • Transplantation of epiphyseal plate allografts between animals of different ages
    • Stevens DG, Boyer MI, Bowen CV: Transplantation of epiphyseal plate allografts between animals of different ages. J Pediatr Orthop 1999;19:398-403.
    • (1999) J Pediatr Orthop , vol.19 , pp. 398-403
    • Stevens, D.G.1    Boyer, M.I.2    Bowen, C.V.3
  • 11
    • 0028260333 scopus 로고
    • Growth hormone (GH) insensitivity due to primary GH receptor deficiency
    • Rosenfeld RG, Rosenbloom AL, Guevara-Aguirre J: Growth hormone (GH) insensitivity due to primary GH receptor deficiency. Endocr Rev 1994;15:369-390.
    • (1994) Endocr Rev , vol.15 , pp. 369-390
    • Rosenfeld, R.G.1    Rosenbloom, A.L.2    Guevara-Aguirre, J.3
  • 12
    • 0030065486 scopus 로고    scopus 로고
    • Spontaneous growth and response to growth hormone treatment in children with growth hormone deficiency and idiopathic short stature
    • Wit JM, Kamp GA, Rikken B: Spontaneous growth and response to growth hormone treatment in children with growth hormone deficiency and idiopathic short stature. Pediatr Res 1996;39:295-302.
    • (1996) Pediatr Res , vol.39 , pp. 295-302
    • Wit, J.M.1    Kamp, G.A.2    Rikken, B.3
  • 13
    • 0029805072 scopus 로고    scopus 로고
    • Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene
    • Woods KA, Camacho-Hubner C, Savage MO, Clark AJ: Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. N Engl J Med 1996;335:1363-1367.
    • (1996) N Engl J Med , vol.335 , pp. 1363-1367
    • Woods, K.A.1    Camacho-Hubner, C.2    Savage, M.O.3    Clark, A.J.4
  • 16
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker J, Liu JP, Robertson EJ, Efstratiadis A: Role of insulin-like growth factors in embryonic and postnatal growth. Cell 1993;75:73-82.
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 18
    • 85047682715 scopus 로고    scopus 로고
    • Minireview: Tissue-specific versus generalized gene targeting of the igf1 and igf1r genes and their roles in insulin-like growth factor physiology
    • Butler AA, LeRoith D: Minireview: tissue-specific versus generalized gene targeting of the igf1 and igf1r genes and their roles in insulin-like growth factor physiology. Endocrinology 2001;142:1685-1688.
    • (2001) Endocrinology , vol.142 , pp. 1685-1688
    • Butler, A.A.1    LeRoith, D.2
  • 20
    • 0031015949 scopus 로고    scopus 로고
    • Two-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: Comparison of two dosage levels and to GH-treated GH deficiency
    • Guevara-Aguirre J, Rosenbloom AL, Vasconez O, Martinez V, Gargosky SE, Allen L, Rosenfeld RG: Two-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: comparison of two dosage levels and to GH-treated GH deficiency. J Clin Endocrinol Metab 1997;82:629-633.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 629-633
    • Guevara-Aguirre, J.1    Rosenbloom, A.L.2    Vasconez, O.3    Martinez, V.4    Gargosky, S.E.5    Allen, L.6    Rosenfeld, R.G.7
  • 22
    • 0020322398 scopus 로고
    • Growth hormone stimulates longitudinal bone growth directly
    • Isaksson OG, Jansson JO, Gause IA: Growth hormone stimulates longitudinal bone growth directly. Science 1982;216:1237-1239.
    • (1982) Science , vol.216 , pp. 1237-1239
    • Isaksson, O.G.1    Jansson, J.O.2    Gause, I.A.3
  • 23
    • 0023878410 scopus 로고
    • Regulation of insulin-like growth factor messenger ribonucleic acid in rat growth plate by growth hormone
    • Isgaard J, Moller C, Isaksson OG, Nilsson A, Mathews LS, Norstedt G: Regulation of insulin-like growth factor messenger ribonucleic acid in rat growth plate by growth hormone. Endocrinology 1988;122:1515-1520.
    • (1988) Endocrinology , vol.122 , pp. 1515-1520
    • Isgaard, J.1    Moller, C.2    Isaksson, O.G.3    Nilsson, A.4    Mathews, L.S.5    Norstedt, G.6
  • 24
    • 0023024908 scopus 로고
    • Evidence suggesting that the direct growth-promoting effect of growth hormone on cartilage in vivo is mediated by local production of somatomedin
    • USA
    • Schlechter NL, Russell SM, Spencer EM, Nicoll CS: Evidence suggesting that the direct growth-promoting effect of growth hormone on cartilage in vivo is mediated by local production of somatomedin. Proc Natl Acad Sci USA 1986;83:7932-7934.
    • (1986) Proc Natl Acad Sci , vol.83 , pp. 7932-7934
    • Schlechter, N.L.1    Russell, S.M.2    Spencer, E.M.3    Nicoll, C.S.4
  • 25
    • 0026702474 scopus 로고
    • Growth hormone induces multiplication of the slowly cycling germinal cells of the rat tibial growth plate
    • USA
    • Ohlsson C, Nilsson A, Isaksson O, Lindahl A: Growth hormone induces multiplication of the slowly cycling germinal cells of the rat tibial growth plate. Proc Natl Acad Sci USA 1992; 89:9826-9830.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 9826-9830
    • Ohlsson, C.1    Nilsson, A.2    Isaksson, O.3    Lindahl, A.4
  • 26
    • 0023446097 scopus 로고
    • Mechanism of the stimulatory effect of growth hormone on longitudinal bone growth
    • Isaksson OG, Lindahl A, Nilsson A, Isgaard J: Mechanism of the stimulatory effect of growth hormone on longitudinal bone growth. Endocr Rev 1987;8:426-438.
    • (1987) Endocr Rev , vol.8 , pp. 426-438
    • Isaksson, O.G.1    Lindahl, A.2    Nilsson, A.3    Isgaard, J.4
  • 27
    • 0028331261 scopus 로고
    • Differential effects of insulin-like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytes in vivo
    • Hunziker EB, Wagner J, Zapf J: Differential effects of insulin-like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytes in vivo. J Clin Invest 1994;93:1078-1086.
    • (1994) J Clin Invest , vol.93 , pp. 1078-1086
    • Hunziker, E.B.1    Wagner, J.2    Zapf, J.3
  • 28
    • 0032751087 scopus 로고    scopus 로고
    • Igf1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy
    • Wang J, Zhou J, Bondy CA: Igf1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy. FASEB J 1999;13:1985-1990.
    • (1999) FASEB J , vol.13 , pp. 1985-1990
    • Wang, J.1    Zhou, J.2    Bondy, C.A.3
  • 29
    • 0033990306 scopus 로고    scopus 로고
    • Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosterone
    • Silvestrini G, Ballanti P, Patacchioli FR, Mocetti P, Di Grezia R, Wedard BM, Angelucci L, Bonucci E: Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosterone. Bone 2000;26:33-42.
    • (2000) Bone , vol.26 , pp. 33-42
    • Silvestrini, G.1    Ballanti, P.2    Patacchioli, F.R.3    Mocetti, P.4    Di Grezia, R.5    Wedard, B.M.6    Angelucci, L.7    Bonucci, E.8
  • 30
    • 0037354059 scopus 로고    scopus 로고
    • Growth retardation induced by dexamethasone is associated with increased apoptosis of the growth plate chondrocytes
    • Chrysis D, Ritzen EM, Savendahl L: Growth retardation induced by dexamethasone is associated with increased apoptosis of the growth plate chondrocytes. J Endocrinol 2003;176: 331-337.
    • (2003) J Endocrinol , vol.176 , pp. 331-337
    • Chrysis, D.1    Ritzen, E.M.2    Savendahl, L.3
  • 31
    • 0031759740 scopus 로고    scopus 로고
    • Dexamethasone impairs growth hormone (GH)-stimulated growth by suppression of local insulin-like growth factor (IGF)-I production and expression of GH- And IGF-I-receptor in cultured rat chondrocytes
    • Jux C, Leiber K, Hugel U, Blum W, Ohlsson C, Klaus G, Mehls O: Dexamethasone impairs growth hormone (GH)-stimulated growth by suppression of local insulin-like growth factor (IGF)-I production and expression of GH- and IGF-I-receptor in cultured rat chondrocytes. Endocrinology 1998;139:3296-3305.
    • (1998) Endocrinology , vol.139 , pp. 3296-3305
    • Jux, C.1    Leiber, K.2    Hugel, U.3    Blum, W.4    Ohlsson, C.5    Klaus, G.6    Mehls, O.7
  • 32
  • 33
    • 0038716012 scopus 로고    scopus 로고
    • Short-term glucocorticoid treatment of prepubertal mice decreases growth and IGF-I expression in the growth plate
    • Smink JJ, Gresnigt MG, Hamers N, Koedam JA, Berger R, van Buul-Offers SC: Short-term glucocorticoid treatment of prepubertal mice decreases growth and IGF-I expression in the growth plate. J Endocrinol 2003;177:381-388.
    • (2003) J Endocrinol , vol.177 , pp. 381-388
    • Smink, J.J.1    Gresnigt, M.G.2    Hamers, N.3    Koedam, J.A.4    Berger, R.5    Van Buul-Offers, S.C.6
  • 34
    • 0036802265 scopus 로고    scopus 로고
    • IGF and IGF-binding protein expression in the growth plate of normal, dexamethasone-treated and human IGF-II transgenic mice
    • Smink JJ, Koster JG, Gresnigt MG, Rooman R, Koedam JA, van Buul-Offers SC: IGF and IGF-binding protein expression in the growth plate of normal, dexamethasone-treated and human IGF-II transgenic mice. J Endocrinol 2002;175:143-153.
    • (2002) J Endocrinol , vol.175 , pp. 143-153
    • Smink, J.J.1    Koster, J.G.2    Gresnigt, M.G.3    Rooman, R.4    Koedam, J.A.5    Van Buul-Offers, S.C.6
  • 36
    • 84995856149 scopus 로고
    • Suppressed spontaneous and stimulated growth hormone secretion in patients with Cushing's disease before and after surgical cure
    • Magiakou MA, Mastorakos G, Gomez MT, Rose SR, Chrousos GP: Suppressed spontaneous and stimulated growth hormone secretion in patients with Cushing's disease before and after surgical cure. J Clin Endocrinol Metab 1994;78:131-137.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 131-137
    • Magiakou, M.A.1    Mastorakos, G.2    Gomez, M.T.3    Rose, S.R.4    Chrousos, G.P.5
  • 37
    • 0028816712 scopus 로고
    • Growth and the growth hormone axis in prepubertal children with asthma
    • Crowley S, Hindmarsh PC, Matthews DR, Brook CG: Growth and the growth hormone axis in prepubertal children with asthma. J Pediatr 1995;126:297-303.
    • (1995) J Pediatr , vol.126 , pp. 297-303
    • Crowley, S.1    Hindmarsh, P.C.2    Matthews, D.R.3    Brook, C.G.4
  • 40
    • 0024500683 scopus 로고
    • Congenital hypothyroidism: Decreased growth velocity in the first weeks of life
    • Leger J, Czernichow P: Congenital hypothyroidism: decreased growth velocity in the first weeks of life. Biol Neonate 1989;55:218-223.
    • (1989) Biol Neonate , vol.55 , pp. 218-223
    • Leger, J.1    Czernichow, P.2
  • 41
    • 0033697747 scopus 로고    scopus 로고
    • Thyroid hormones regulate hypertrophic chondrocyte differentiation and expression of parathyroid hormone-related peptide and its receptor during endochondral bone formation
    • Stevens DA, Hasserjian RP, Robson H, Siebler T, Shalet SM, Williams GR: Thyroid hormones regulate hypertrophic chondrocyte differentiation and expression of parathyroid hormone-related peptide and its receptor during endochondral bone formation. J Bone Miner Res 2000;15:2431-2442.
    • (2000) J Bone Miner Res , vol.15 , pp. 2431-2442
    • Stevens, D.A.1    Hasserjian, R.P.2    Robson, H.3    Siebler, T.4    Shalet, S.M.5    Williams, G.R.6
  • 42
    • 0036183348 scopus 로고    scopus 로고
    • Thyroid hormones promote chondrocyte differentiation in mouse ATDC5 cells and stimulate endochondral ossification in fetal mouse tibias through iodothyronine deiodinases in the growth plate
    • Miura M, Tanaka K, Komatsu Y, Suda M, Yasoda A, Sakuma Y, Ozasa A, Nakao K: Thyroid hormones promote chondrocyte differentiation in mouse ATDC5 cells and stimulate endochondral ossification in fetal mouse tibias through iodothyronine deiodinases in the growth plate. J Bone Miner Res 2002;17:443-454.
    • (2002) J Bone Miner Res , vol.17 , pp. 443-454
    • Miura, M.1    Tanaka, K.2    Komatsu, Y.3    Suda, M.4    Yasoda, A.5    Sakuma, Y.6    Ozasa, A.7    Nakao, K.8
  • 43
    • 0033752854 scopus 로고    scopus 로고
    • Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation
    • Robson H, Siebler T, Stevens DA, Shalet SM, Williams GR: Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation. Endocrinology 2000;141:3887-3897.
    • (2000) Endocrinology , vol.141 , pp. 3887-3897
    • Robson, H.1    Siebler, T.2    Stevens, D.A.3    Shalet, S.M.4    Williams, G.R.5
  • 44
    • 0032858527 scopus 로고    scopus 로고
    • Expression of thyroid hormone receptor isoforms in rat growth plate cartilage in vivo
    • Ballock R, Mita BC, Zhou X, Chen DH, Mink LM: Expression of thyroid hormone receptor isoforms in rat growth plate cartilage in vivo. J Bone Miner Res 1999;14:1550-1556.
    • (1999) J Bone Miner Res , vol.14 , pp. 1550-1556
    • Ballock, R.1    Mita, B.C.2    Zhou, X.3    Chen, D.H.4    Mink, L.M.5
  • 45
    • 0033081046 scopus 로고    scopus 로고
    • Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development
    • Gauthier K, Chassande O, Plateroti M, Roux JP, Legrand C, Pain B, Rousset B, Weiss R, Trouillas J, Samarut J: Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development. EMBO J 1999;18:623-631.
    • (1999) EMBO J , vol.18 , pp. 623-631
    • Gauthier, K.1    Chassande, O.2    Plateroti, M.3    Roux, J.P.4    Legrand, C.5    Pain, B.6    Rousset, B.7    Weiss, R.8    Trouillas, J.9    Samarut, J.10
  • 46
    • 0026511358 scopus 로고
    • Recessive inheritance of thyroid hormone resistance caused by complete deletion of the protein-coding region of the thyroid hormone receptor-beta gene
    • Takeda K, Sakurai A, Degroot LJ, Refetoff S: Recessive inheritance of thyroid hormone resistance caused by complete deletion of the protein-coding region of the thyroid hormone receptor-beta gene. J Clin Endocrinol Metab 1992;74:49-55.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 49-55
    • Takeda, K.1    Sakurai, A.2    Degroot, L.J.3    Refetoff, S.4
  • 47
    • 0034768522 scopus 로고    scopus 로고
    • GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor alpha 1-/-beta-/- Mice
    • Kindblom JM, Gothe S, Forrest D, Tornell J, Tornell J, Vennstrom B, Ohlsson C: GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor alpha 1-/-beta-/- mice. J Endocrinol 2001;171:15-22.
    • (2001) J Endocrinol , vol.171 , pp. 15-22
    • Kindblom, J.M.1    Gothe, S.2    Forrest, D.3    Tornell, J.4    Tornell, J.5    Vennstrom, B.6    Ohlsson, C.7
  • 48
    • 0028143234 scopus 로고
    • Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man
    • published erratum appears in N Engl J Med 1995;332:131
    • Smith EP, Boyd J, Frank GR, Takahashi H, Cohen RM, Specker B, Williams TC, Lubahn DB, Korach KS: Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man [see comments] [published erratum appears in N Engl J Med 1995;332:131]. N Engl J Med 1994;331:1056-1061.
    • (1994) N Engl J Med , vol.331 , pp. 1056-1061
    • Smith, E.P.1    Boyd, J.2    Frank, G.R.3    Takahashi, H.4    Cohen, R.M.5    Specker, B.6    Williams, T.C.7    Lubahn, D.B.8    Korach, K.S.9
  • 49
    • 0028792229 scopus 로고
    • Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens
    • Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K: Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. Clin Endocrinol Metab 1995;80:3689-3698.
    • (1995) Clin Endocrinol Metab , vol.80 , pp. 3689-3698
    • Morishima, A.1    Grumbach, M.M.2    Simpson, E.R.3    Fisher, C.4    Qin, K.5
  • 50
    • 0035796007 scopus 로고    scopus 로고
    • A specific aromatase inhibitor and potential increase in adult height in boys with delayed puberty: A randomised controlled trial
    • Wickman S, Sipila I, Ankarberg-Lindgren C, Norjavaara E, Dunkel L: A specific aromatase inhibitor and potential increase in adult height in boys with delayed puberty: a randomised controlled trial. Lancet 2001;357:1743-1748.
    • (2001) Lancet , vol.357 , pp. 1743-1748
    • Wickman, S.1    Sipila, I.2    Ankarberg-Lindgren, C.3    Norjavaara, E.4    Dunkel, L.5
  • 51
    • 0032788615 scopus 로고    scopus 로고
    • The effects of the estrogen receptor blocker, Faslodex (ICI 182,780), on estrogen-accelerated bone maturation in mice
    • Gunther DF, Calikoglu AS, Underwood LE: The effects of the estrogen receptor blocker, Faslodex (ICI 182,780), on estrogen-accelerated bone maturation in mice. Pediatr Res 1999;46:269-273.
    • (1999) Pediatr Res , vol.46 , pp. 269-273
    • Gunther, D.F.1    Calikoglu, A.S.2    Underwood, L.E.3
  • 52
    • 0041353103 scopus 로고    scopus 로고
    • Tamoxifen treatment for precocious puberty in McCune-Albright syndrome: A multicenter trial
    • Eugster EA, Rubin SD, Reiter EO, Plourde P, Jou HC, Pescovitz OH: Tamoxifen treatment for precocious puberty in McCune-Albright syndrome: a multicenter trial. J Pediatr 2003; 143:60-66.
    • (2003) J Pediatr , vol.143 , pp. 60-66
    • Eugster, E.A.1    Rubin, S.D.2    Reiter, E.O.3    Plourde, P.4    Jou, H.C.5    Pescovitz, O.H.6
  • 53
    • 0037387363 scopus 로고    scopus 로고
    • Raloxifene acts as an estrogen agonist on the rabbit growth plate
    • Nilsson O, Falk J, Ritzen EM, Baron J, Savendahl L: Raloxifene acts as an estrogen agonist on the rabbit growth plate. Endocrinology 2003;144:1481-1485.
    • (2003) Endocrinology , vol.144 , pp. 1481-1485
    • Nilsson, O.1    Falk, J.2    Ritzen, E.M.3    Baron, J.4    Savendahl, L.5
  • 54
    • 0022529328 scopus 로고
    • Pubertal growth in patients with androgen insensitivity: Indirect evidence for the importance of estrogens in pubertal growth of girls
    • Zachmann M, Prader A, Sobel EH, Crigler JF Jr, Ritzen EM, Atares M, Ferrandez A: Pubertal growth in patients with androgen insensitivity: indirect evidence for the importance of estrogens in pubertal growth of girls. J Pediatr 1986;108:694-697.
    • (1986) J Pediatr , vol.108 , pp. 694-697
    • Zachmann, M.1    Prader, A.2    Sobel, E.H.3    Crigler Jr., J.F.4    Ritzen, E.M.5    Atares, M.6    Ferrandez, A.7
  • 55
    • 0034504525 scopus 로고    scopus 로고
    • Estrogen, bone, growth and sex: A sea change in conventional wisdom
    • Grumbach MM: Estrogen, bone, growth and sex: a sea change in conventional wisdom. J Pediatr Endocrinol Metab 2000;13(suppl 6): 1439-1455.
    • (2000) J Pediatr Endocrinol Metab , vol.13 , Issue.6 SUPPL. , pp. 1439-1455
    • Grumbach, M.M.1
  • 56
    • 0031120087 scopus 로고    scopus 로고
    • The role of estrogen in bone growth and maturation during childhood and adolescence
    • Cutler GB Jr: The role of estrogen in bone growth and maturation during childhood and adolescence. J Steroid Biochem Mol Biol 1997; 61:141-144.
    • (1997) J Steroid Biochem Mol Biol , vol.61 , pp. 141-144
    • Cutler Jr., G.B.1
  • 58
    • 0029793054 scopus 로고    scopus 로고
    • A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. II. Estrogen levels as determined by an ultrasensitive bioassay
    • Klein KO, Martha PM Jr, Blizzard RM, Herbst T, Rogol AD: A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. II. Estrogen levels as determined by an ultrasensitive bioassay. J Clin Endocrinol Metab 1996;81:3203-3207.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3203-3207
    • Klein, K.O.1    Martha Jr., P.M.2    Blizzard, R.M.3    Herbst, T.4    Rogol, A.D.5
  • 59
    • 0038476031 scopus 로고    scopus 로고
    • Localization of estrogen receptors-alpha and -beta and androgen receptor in the human growth plate at different pubertal stages
    • Nilsson O, Chrysis D, Pajulo O, Boman A, Holst M, Rubinstein J, Martin RE, Savendahl L: Localization of estrogen receptors-alpha and -beta and androgen receptor in the human growth plate at different pubertal stages. J Endocrinol 2003;177:319-326.
    • (2003) J Endocrinol , vol.177 , pp. 319-326
    • Nilsson, O.1    Chrysis, D.2    Pajulo, O.3    Boman, A.4    Holst, M.5    Rubinstein, J.6    Martin, R.E.7    Savendahl, L.8
  • 60
    • 0020713125 scopus 로고
    • Sites of action of testosterone and estradiol on longitudinal bone growth
    • Jansson JO, Eden S, Isaksson O: Sites of action of testosterone and estradiol on longitudinal bone growth. Am J Physiol 1983;244:135-140.
    • (1983) Am J Physiol , vol.244 , pp. 135-140
    • Jansson, J.O.1    Eden, S.2    Isaksson, O.3
  • 65
    • 0027417528 scopus 로고
    • Androgen-stimulated pubertal growth: The effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty
    • Keenan BS, Richards GE, Ponder SW, Dallas JS, Nagamani M, Smith ER: Androgen-stimulated pubertal growth: the effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty. J Clin Endocrinol Metab 1993;76:996-1001.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 996-1001
    • Keenan, B.S.1    Richards, G.E.2    Ponder, S.W.3    Dallas, J.S.4    Nagamani, M.5    Smith, E.R.6
  • 66
    • 0035663516 scopus 로고    scopus 로고
    • Testosterone stimulates growth of tibial epiphyseal growth plate and insulin-like growth factor-1 receptor abundance in hypophysectomized and castrated rats
    • Phillip M, Maor G, Assa S, Silbergeld A, Segev Y: Testosterone stimulates growth of tibial epiphyseal growth plate and insulin-like growth factor-1 receptor abundance in hypophysectomized and castrated rats. Endocrine 2001;16: 1-6.
    • (2001) Endocrine , vol.16 , pp. 1-6
    • Phillip, M.1    Maor, G.2    Assa, S.3    Silbergeld, A.4    Segev, Y.5
  • 67
    • 0036275585 scopus 로고    scopus 로고
    • Gender differences in expression of androgen receptor in tibial growth plate and metaphyseal bone of the rat
    • van der Eerden BC, van Til NP, Brinkmann AO, Lowik CW, Wit JM, Karperien M: Gender differences in expression of androgen receptor in tibial growth plate and metaphyseal bone of the rat. Bone 2002;30:891-896.
    • (2002) Bone , vol.30 , pp. 891-896
    • Van Der Eerden, B.C.1    Van Til, N.P.2    Brinkmann, A.O.3    Lowik, C.W.4    Wit, J.M.5    Karperien, M.6
  • 69
    • 0024378370 scopus 로고
    • Direct administration of testosterone increases rat tibial epiphyseal growth plate width
    • Copenh
    • Ren SG, Malozowski S, Sanchez P, Sweet DE, Loriaux DL, Cassorla F: Direct administration of testosterone increases rat tibial epiphyseal growth plate width. Acta Endocrinol (Copenh) 1989;121:401-405.
    • (1989) Acta Endocrinol , vol.121 , pp. 401-405
    • Ren, S.G.1    Malozowski, S.2    Sanchez, P.3    Sweet, D.E.4    Loriaux, D.L.5    Cassorla, F.6
  • 70
    • 0242662055 scopus 로고    scopus 로고
    • 1,25(OH)2D3 and dihydrotestosterone interact to regulate proliferation and differentiation of epiphyseal chondrocytes
    • Krohn K, Haffner D, Hugel U, Himmele R, Klaus G, Mehls O, Schaefer F: 1,25(OH)2D3 and dihydrotestosterone interact to regulate proliferation and differentiation of epiphyseal chondrocytes. Calcif Tissue Int 2003;73:400-410.
    • (2003) Calcif Tissue Int , vol.73 , pp. 400-410
    • Krohn, K.1    Haffner, D.2    Hugel, U.3    Himmele, R.4    Klaus, G.5    Mehls, O.6    Schaefer, F.7
  • 71
    • 0032586720 scopus 로고    scopus 로고
    • Testosterone stimulates insulin-like growth factor-I and insulin-like growth factor-I-receptor gene expression in the mandibular condyle - A model of endochondral ossification
    • Maor G, Segev Y, Phillip M: Testosterone stimulates insulin-like growth factor-I and insulin-like growth factor-I-receptor gene expression in the mandibular condyle - a model of endochondral ossification. Endocrinology 1999;140:1901-1910.
    • (1999) Endocrinology , vol.140 , pp. 1901-1910
    • Maor, G.1    Segev, Y.2    Phillip, M.3
  • 72
    • 0034743566 scopus 로고    scopus 로고
    • Effect of lalpha,25-dihydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3 on metalloproteinase activity and cell maturation in growth plate cartilage in vivo
    • Dean DD, Boyan BD, Schwart Z, Muniz OE, Carreno MR, Maeda S, Howell DS: Effect of lalpha,25-dihydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3 on metalloproteinase activity and cell maturation in growth plate cartilage in vivo. Endocrine 2001;14:311-323.
    • (2001) Endocrine , vol.14 , pp. 311-323
    • Dean, D.D.1    Boyan, B.D.2    Schwart, Z.3    Muniz, O.E.4    Carreno, M.R.5    Maeda, S.6    Howell, D.S.7
  • 73
    • 0036720621 scopus 로고    scopus 로고
    • Rickets in VDR null mice is secondary to decreased apoptosis of hypertrophic chondrocytes
    • Donohue MM, Demay MB: Rickets in VDR null mice is secondary to decreased apoptosis of hypertrophic chondrocytes. Endocrinology 2002;143:3691-3694.
    • (2002) Endocrinology , vol.143 , pp. 3691-3694
    • Donohue, M.M.1    Demay, M.B.2
  • 74
    • 0033303655 scopus 로고    scopus 로고
    • Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: Formal histomorphometric and biomechanical analyses
    • Amling M, Priemel M, Holzmann T, Chapin K, Rueger JM, Baron R, Demay MB: Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: formal histomorphometric and biomechanical analyses. Endocrinology 1999;140:4982-4987.
    • (1999) Endocrinology , vol.140 , pp. 4982-4987
    • Amling, M.1    Priemel, M.2    Holzmann, T.3    Chapin, K.4    Rueger, J.M.5    Baron, R.6    Demay, M.B.7
  • 75
    • 0021447735 scopus 로고
    • Vitamin D is not directly necessary for bone growth and mineralization
    • Underwood JL, DeLuca HF: Vitamin D is not directly necessary for bone growth and mineralization. Am J Physiol 1984;246:E493-E498.
    • (1984) Am J Physiol , vol.246
    • Underwood, J.L.1    DeLuca, H.F.2
  • 76
    • 0023322196 scopus 로고
    • Healing of rachitic lesions in chicks by 24R,25-dihydroxycholecalciferol administered locally into bone
    • Lidor C, Atkin I, Ornoy A, Dekel S, Edelstein S: Healing of rachitic lesions in chicks by 24R,25-dihydroxycholecalciferol administered locally into bone. J Bone Miner Res 1987;2:91-98.
    • (1987) J Bone Miner Res , vol.2 , pp. 91-98
    • Lidor, C.1    Atkin, I.2    Ornoy, A.3    Dekel, S.4    Edelstein, S.5
  • 77
    • 0036074043 scopus 로고    scopus 로고
    • Differential regulation of growth plate chondrocytes by 1alpha,25-(OH)2D3 and 24R,25-(OH)2D3 involves cell-maturation-specific membrane-receptor- activated phospholipid metabolism
    • Boyan BD, Sylvia VL, Dean DD, Del Toro F, Schwartz Z: Differential regulation of growth plate chondrocytes by 1alpha,25-(OH)2D3 and 24R,25-(OH)2D3 involves cell-maturation-specific membrane-receptor-activated phospholipid metabolism. Crit Rev Oral Biol Med 2002;13:143-154.
    • (2002) Crit Rev Oral Biol Med , vol.13 , pp. 143-154
    • Boyan, B.D.1    Sylvia, V.L.2    Dean, D.D.3    Del Toro, F.4    Schwartz, Z.5
  • 78
    • 85047681343 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D(3) and 24R,25-dihydroxyvitamin D(3) modulate growth plate chondrocyte physiology via protein kinase C-dependent phosphorylation of extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase
    • Schwartz Z, Ehland H, Sylvia VL, Larsson D, Hardin RR, Bingham V, Lopez D, Dean DD, Boyan BD: 1alpha,25-dihydroxyvitamin D(3) and 24R,25- dihydroxyvitamin D(3) modulate growth plate chondrocyte physiology via protein kinase C-dependent phosphorylation of extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase. Endocrinology 2002;143:2775-2786.
    • (2002) Endocrinology , vol.143 , pp. 2775-2786
    • Schwartz, Z.1    Ehland, H.2    Sylvia, V.L.3    Larsson, D.4    Hardin, R.R.5    Bingham, V.6    Lopez, D.7    Dean, D.D.8    Boyan, B.D.9
  • 79
    • 0035543988 scopus 로고    scopus 로고
    • 1alpha,25-(OH)2D3 regulates 25-hydroxyvitamin D3 24R-hydroxylase activity in growth zone costochondral growth plate chondrocytes via protein kinase C
    • Schwartz Z, Pedrozo HA, Sylvia VL, Gomez R, Dean DD, Boyan BD: 1alpha,25-(OH)2D3 regulates 25-hydroxyvitamin D3 24R-hydroxylase activity in growth zone costochondral growth plate chondrocytes via protein kinase C. Calcif Tissue Int 2001;69:365-372.
    • (2001) Calcif Tissue Int , vol.69 , pp. 365-372
    • Schwartz, Z.1    Pedrozo, H.A.2    Sylvia, V.L.3    Gomez, R.4    Dean, D.D.5    Boyan, B.D.6
  • 83
    • 0033304576 scopus 로고    scopus 로고
    • Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
    • Ozata M, Ozdemir IC, Licinio J: Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. J Clin Endocrinol Metab 1999;84:3686-3695.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3686-3695
    • Ozata, M.1    Ozdemir, I.C.2    Licinio, J.3
  • 84
    • 0035999436 scopus 로고    scopus 로고
    • Leptin acts as a growth factor on the chondrocytes of skeletal growth centers
    • Maor G, Rochwerger M, Segev Y, Phillip M: Leptin acts as a growth factor on the chondrocytes of skeletal growth centers. J Bone Miner Res 2002;17:1034-1043.
    • (2002) J Bone Miner Res , vol.17 , pp. 1034-1043
    • Maor, G.1    Rochwerger, M.2    Segev, Y.3    Phillip, M.4
  • 85
    • 0042242698 scopus 로고    scopus 로고
    • Effects of leptin to cultured growth plate chondrocytes
    • Nakajima R, Inada H, Koike T, Yamano T: Effects of leptin to cultured growth plate chondrocytes. Horm Res 2003;60:91-98.
    • (2003) Horm Res , vol.60 , pp. 91-98
    • Nakajima, R.1    Inada, H.2    Koike, T.3    Yamano, T.4
  • 87
    • 0030033150 scopus 로고    scopus 로고
    • Nonsense mutation in the human growth hormone-releasing hormone receptor causes growth failure analogous to the little (lit) mouse
    • Wajnrajch MP, Gertner JM, Harbison MD, Chua SC Jr, Leibel RL: Nonsense mutation in the human growth hormone-releasing hormone receptor causes growth failure analogous to the little (lit) mouse. Nat Genet 1996;12: 88-90.
    • (1996) Nat Genet , vol.12 , pp. 88-90
    • Wajnrajch, M.P.1    Gertner, J.M.2    Harbison, M.D.3    Chua Jr., S.C.4    Leibel, R.L.5
  • 88
    • 0031890209 scopus 로고    scopus 로고
    • Prevalence of human GH-1 gene alterations in patients with isolated growth hormone deficiency
    • Wagner JK, Eble A, Hindmarsh PC, Mullis PE: Prevalence of human GH-1 gene alterations in patients with isolated growth hormone deficiency. Pediatr Res 1998;43:105-110.
    • (1998) Pediatr Res , vol.43 , pp. 105-110
    • Wagner, J.K.1    Eble, A.2    Hindmarsh, P.C.3    Mullis, P.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.