메뉴 건너뛰기




Volumn 14, Issue 2, 2012, Pages

Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; INTERLEUKIN 1; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR EGR 1; TRANSCRIPTION FACTOR SP1; EARLY GROWTH RESPONSE FACTOR 1; EGR1 PROTEIN, HUMAN;

EID: 84858966476     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar3788     Document Type: Article
Times cited : (29)

References (57)
  • 1
    • 78650983649 scopus 로고    scopus 로고
    • Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
    • 10.1038/nrrheum.2010.196, 21119608
    • Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 2011, 7:33-42. 10.1038/nrrheum.2010.196, 21119608.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 33-42
    • Kapoor, M.1    Martel-Pelletier, J.2    Lajeunesse, D.3    Pelletier, J.P.4    Fahmi, H.5
  • 3
    • 77955057772 scopus 로고    scopus 로고
    • PPARalpha: an emerging therapeutic target in diabetic microvascular damage
    • 10.1038/nrendo.2010.89, 20567246
    • Hiukka A, Maranghi M, Matikainen N, Taskinen MR. PPARalpha: an emerging therapeutic target in diabetic microvascular damage. Nat Rev Endocrinol 2010, 6:454-463. 10.1038/nrendo.2010.89, 20567246.
    • (2010) Nat Rev Endocrinol , vol.6 , pp. 454-463
    • Hiukka, A.1    Maranghi, M.2    Matikainen, N.3    Taskinen, M.R.4
  • 4
    • 55949111070 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor beta/delta in the brain: facts and hypothesis
    • 2581793, 19009042
    • Hall MG, Quignodon L, Desvergne B. Peroxisome proliferator-activated receptor beta/delta in the brain: facts and hypothesis. PPAR Res 2008, 2008:780452. 2581793, 19009042.
    • (2008) PPAR Res , vol.2008 , pp. 780452
    • Hall, M.G.1    Quignodon, L.2    Desvergne, B.3
  • 5
    • 77957898893 scopus 로고    scopus 로고
    • Therapeutic potential of peroxisome proliferator-activated receptors in chronic inflammation and colorectal cancer
    • 10.1016/j.gtc.2010.08.014, 2957674, 20951925
    • Wang D, DuBois RN. Therapeutic potential of peroxisome proliferator-activated receptors in chronic inflammation and colorectal cancer. Gastroenterol Clin North Am 2010, 39:697-707. 10.1016/j.gtc.2010.08.014, 2957674, 20951925.
    • (2010) Gastroenterol Clin North Am , vol.39 , pp. 697-707
    • Wang, D.1    DuBois, R.N.2
  • 6
    • 79952337610 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor-gamma in atherosclerosis: an update
    • 10.1253/circj.CJ-11-0060, 21325726
    • Wang N, Yin R, Liu Y, Mao G, Xi F. Role of peroxisome proliferator-activated receptor-gamma in atherosclerosis: an update. Circ J 2011, 75:528-535. 10.1253/circj.CJ-11-0060, 21325726.
    • (2011) Circ J , vol.75 , pp. 528-535
    • Wang, N.1    Yin, R.2    Liu, Y.3    Mao, G.4    Xi, F.5
  • 7
    • 79961244975 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and cancer: challenges and opportunities
    • 10.1111/j.1476-5381.2011.01383.x, 21449912
    • Youssef J, Badr M. Peroxisome proliferator-activated receptors and cancer: challenges and opportunities. Br J Pharmacol 2011, 164:68-82. 10.1111/j.1476-5381.2011.01383.x, 21449912.
    • (2011) Br J Pharmacol , vol.164 , pp. 68-82
    • Youssef, J.1    Badr, M.2
  • 8
    • 79951942686 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma in osteoarthritis
    • 10.1007/s10165-010-0347-x, 20820843
    • Fahmi H, Martel-Pelletier J, Pelletier JP, Kapoor M. Peroxisome proliferator-activated receptor gamma in osteoarthritis. Mod Rheumatol 2011, 21:1-9. 10.1007/s10165-010-0347-x, 20820843.
    • (2011) Mod Rheumatol , vol.21 , pp. 1-9
    • Fahmi, H.1    Martel-Pelletier, J.2    Pelletier, J.P.3    Kapoor, M.4
  • 9
    • 0035083913 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes
    • 10.1002/1529-0131(200103)44:3<595::AID-ANR108>3.0.CO;2-8, 11263774
    • Fahmi H, Di Battista JA, Pelletier JP, Mineau F, Ranger P, Martel-Pelletier J. Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes. Arthritis Rheum 2001, 44:595-607. 10.1002/1529-0131(200103)44:3<595::AID-ANR108>3.0.CO;2-8, 11263774.
    • (2001) Arthritis Rheum , vol.44 , pp. 595-607
    • Fahmi, H.1    Di Battista, J.A.2    Pelletier, J.P.3    Mineau, F.4    Ranger, P.5    Martel-Pelletier, J.6
  • 10
    • 0036854541 scopus 로고    scopus 로고
    • 15d-PGJ(2) is acting as a 'dual agent' on the regulation of COX-2 expression in human osteoarthritic chondrocytes
    • 10.1053/joca.2002.0835, 12435328
    • Fahmi H, Pelletier JP, Mineau F, Martel-Pelletier J. 15d-PGJ(2) is acting as a 'dual agent' on the regulation of COX-2 expression in human osteoarthritic chondrocytes. Osteoarthritis Cartilage 2002, 10:845-848. 10.1053/joca.2002.0835, 12435328.
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 845-848
    • Fahmi, H.1    Pelletier, J.P.2    Mineau, F.3    Martel-Pelletier, J.4
  • 11
    • 0034697146 scopus 로고    scopus 로고
    • Evidence for the presence of peroxisome proliferator-activated receptor (PPAR) alpha and gamma and retinoid Z receptor in cartilage. PPARgamma activation modulates the effects of interleukin-1beta on rat chondrocytes
    • 10.1074/jbc.275.16.12243, 10766862
    • Bordji K, Grillasca JP, Gouze JN, Magdalou J, Schohn H, Keller JM, Bianchi A, Dauca M, Netter P, Terlain B. Evidence for the presence of peroxisome proliferator-activated receptor (PPAR) alpha and gamma and retinoid Z receptor in cartilage. PPARgamma activation modulates the effects of interleukin-1beta on rat chondrocytes. J Biol Chem 2000, 275:12243-12250. 10.1074/jbc.275.16.12243, 10766862.
    • (2000) J Biol Chem , vol.275 , pp. 12243-12250
    • Bordji, K.1    Grillasca, J.P.2    Gouze, J.N.3    Magdalou, J.4    Schohn, H.5    Keller, J.M.6    Bianchi, A.7    Dauca, M.8    Netter, P.9    Terlain, B.10
  • 13
    • 18744408157 scopus 로고    scopus 로고
    • Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes
    • Li X, Afif H, Cheng S, Martel-Pelletier J, Pelletier JP, Ranger P, Fahmi H. Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes. J Rheumatol 2005, 32:887-895.
    • (2005) J Rheumatol , vol.32 , pp. 887-895
    • Li, X.1    Afif, H.2    Cheng, S.3    Martel-Pelletier, J.4    Pelletier, J.P.5    Ranger, P.6    Fahmi, H.7
  • 14
    • 33644664887 scopus 로고    scopus 로고
    • Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2
    • 10.1186/ar1830, 1297580, 16277686
    • Bianchi A, Moulin D, Sebillaud S, Koufany M, Galteau MM, Netter P, Terlain B, Jouzeau JY. Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2. Arthritis Res Ther 2005, 7:R1325-1337. 10.1186/ar1830, 1297580, 16277686.
    • (2005) Arthritis Res Ther , vol.7
    • Bianchi, A.1    Moulin, D.2    Sebillaud, S.3    Koufany, M.4    Galteau, M.M.5    Netter, P.6    Terlain, B.7    Jouzeau, J.Y.8
  • 15
    • 18244420377 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma down-regulates chondrocyte matrix metalloproteinase-1 via a novel composite element
    • 10.1074/jbc.M312708200, 15090544
    • Francois M, Richette P, Tsagris L, Raymondjean M, Fulchignoni-Lataud MC, Forest C, Savouret JF, Corvol MT. Peroxisome proliferator-activated receptor-gamma down-regulates chondrocyte matrix metalloproteinase-1 via a novel composite element. J Biol Chem 2004, 279:28411-28418. 10.1074/jbc.M312708200, 15090544.
    • (2004) J Biol Chem , vol.279 , pp. 28411-28418
    • Francois, M.1    Richette, P.2    Tsagris, L.3    Raymondjean, M.4    Fulchignoni-Lataud, M.C.5    Forest, C.6    Savouret, J.F.7    Corvol, M.T.8
  • 17
    • 0035508145 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) on the expression of inflammatory cytokines and apoptosis induction in rheumatoid synovial fibroblasts and monocytes
    • 10.1006/jaut.2001.0542, 11712859
    • Ji JD, Cheon H, Jun JB, Choi SJ, Kim YR, Lee YH, Kim TH, Chae IJ, Song GG, Yoo DH, Kim SY, Sohn J. Effects of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) on the expression of inflammatory cytokines and apoptosis induction in rheumatoid synovial fibroblasts and monocytes. J Autoimmun 2001, 17:215-221. 10.1006/jaut.2001.0542, 11712859.
    • (2001) J Autoimmun , vol.17 , pp. 215-221
    • Ji, J.D.1    Cheon, H.2    Jun, J.B.3    Choi, S.J.4    Kim, Y.R.5    Lee, Y.H.6    Kim, T.H.7    Chae, I.J.8    Song, G.G.9    Yoo, D.H.10    Kim, S.Y.11    Sohn, J.12
  • 19
    • 0036151348 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma acitvators inhibit MMP-1 production in human synovial fibroblasts by reducing the activity of the activator protein 1
    • 10.1053/joca.2001.0485, 11869069
    • Fahmi H, Pelletier JP, Di Battista JA, Cheung HS, Fernandes J, Martel-Pelletier J. Peroxisome proliferator-activated receptor gamma acitvators inhibit MMP-1 production in human synovial fibroblasts by reducing the activity of the activator protein 1. Osteoarthritis Cartilage 2002, 10:100-108. 10.1053/joca.2001.0485, 11869069.
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 100-108
    • Fahmi, H.1    Pelletier, J.P.2    Di Battista, J.A.3    Cheung, H.S.4    Fernandes, J.5    Martel-Pelletier, J.6
  • 20
    • 0034809490 scopus 로고    scopus 로고
    • Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2
    • 10.1006/bbrc.2001.4847, 11350047
    • Tsubouchi Y, Kawahito Y, Kohno M, Inoue K, Hla T, Sano H. Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2. Biochem Biophys Res Commun 2001, 283:750-755. 10.1006/bbrc.2001.4847, 11350047.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 750-755
    • Tsubouchi, Y.1    Kawahito, Y.2    Kohno, M.3    Inoue, K.4    Hla, T.5    Sano, H.6
  • 21
    • 12344252611 scopus 로고    scopus 로고
    • Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism
    • 10.1002/art.20714, 15641079
    • Farrajota K, Cheng S, Martel-Pelletier J, Afif H, Pelletier JP, Li X, Ranger P, Fahmi H. Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism. Arthritis Rheum 2005, 52:94-104. 10.1002/art.20714, 15641079.
    • (2005) Arthritis Rheum , vol.52 , pp. 94-104
    • Farrajota, K.1    Cheng, S.2    Martel-Pelletier, J.3    Afif, H.4    Pelletier, J.P.5    Li, X.6    Ranger, P.7    Fahmi, H.8
  • 22
    • 2542491986 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1
    • 10.1074/jbc.M402828200, 15023995
    • Cheng S, Afif H, Martel-Pelletier J, Pelletier JP, Li X, Farrajota K, Lavigne M, Fahmi H. Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. J Biol Chem 2004, 279:22057-22065. 10.1074/jbc.M402828200, 15023995.
    • (2004) J Biol Chem , vol.279 , pp. 22057-22065
    • Cheng, S.1    Afif, H.2    Martel-Pelletier, J.3    Pelletier, J.P.4    Li, X.5    Farrajota, K.6    Lavigne, M.7    Fahmi, H.8
  • 23
    • 13444271580 scopus 로고    scopus 로고
    • Pioglitazone, a peroxisome proliferator-activated receptor gamma agonist, reduces the progression of experimental osteoarthritis in guinea pigs
    • 10.1002/art.20792, 15692987
    • Kobayashi T, Notoya K, Naito T, Unno S, Nakamura A, Martel-Pelletier J, Pelletier JP. Pioglitazone, a peroxisome proliferator-activated receptor gamma agonist, reduces the progression of experimental osteoarthritis in guinea pigs. Arthritis Rheum 2005, 52:479-487. 10.1002/art.20792, 15692987.
    • (2005) Arthritis Rheum , vol.52 , pp. 479-487
    • Kobayashi, T.1    Notoya, K.2    Naito, T.3    Unno, S.4    Nakamura, A.5    Martel-Pelletier, J.6    Pelletier, J.P.7
  • 24
    • 34547471112 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor gamma agonist pioglitazone reduces the development of cartilage lesions in an experimental dog model of osteoarthritis: in vivo protective effects mediated through the inhibition of key signaling and catabolic pathways
    • 10.1002/art.22726, 17599749
    • Boileau C, Martel-Pelletier J, Fahmi H, Mineau F, Boily M, Pelletier JP. The peroxisome proliferator-activated receptor gamma agonist pioglitazone reduces the development of cartilage lesions in an experimental dog model of osteoarthritis: in vivo protective effects mediated through the inhibition of key signaling and catabolic pathways. Arthritis Rheum 2007, 56:2288-2298. 10.1002/art.22726, 17599749.
    • (2007) Arthritis Rheum , vol.56 , pp. 2288-2298
    • Boileau, C.1    Martel-Pelletier, J.2    Fahmi, H.3    Mineau, F.4    Boily, M.5    Pelletier, J.P.6
  • 25
    • 34247196696 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes
    • 10.1186/ar2151, 1906809, 17386086
    • Afif H, Benderdour M, Mfuna-Endam L, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes. Arthritis Res Ther 2007, 9:R31. 10.1186/ar2151, 1906809, 17386086.
    • (2007) Arthritis Res Ther , vol.9
    • Afif, H.1    Benderdour, M.2    Mfuna-Endam, L.3    Martel-Pelletier, J.4    Pelletier, J.P.5    Duval, N.6    Fahmi, H.7
  • 26
    • 0023506743 scopus 로고
    • Criteria for the classification of osteoarthritis of the knee and hip
    • Altman RD. Criteria for the classification of osteoarthritis of the knee and hip. Scand J Rheumatol Suppl 1987, 65:31-39.
    • (1987) Scand J Rheumatol Suppl , vol.65 , pp. 31-39
    • Altman, R.D.1
  • 28
    • 34548408743 scopus 로고    scopus 로고
    • Interleukin-1 beta-induced Id2 gene expression is mediated by Egr-1 in vascular smooth muscle cells
    • 10.1016/j.cardiores.2007.06.015, 2094110, 17631285
    • Zhu X, Lin Y, Bacanamwo M, Chang L, Chai R, Massud I, Zhang J, Garcia-Barrio MT, Thompson WE, Chen YE. Interleukin-1 beta-induced Id2 gene expression is mediated by Egr-1 in vascular smooth muscle cells. Cardiovasc Res 2007, 76:141-148. 10.1016/j.cardiores.2007.06.015, 2094110, 17631285.
    • (2007) Cardiovasc Res , vol.76 , pp. 141-148
    • Zhu, X.1    Lin, Y.2    Bacanamwo, M.3    Chang, L.4    Chai, R.5    Massud, I.6    Zhang, J.7    Garcia-Barrio, M.T.8    Thompson, W.E.9    Chen, Y.E.10
  • 29
    • 44749090905 scopus 로고    scopus 로고
    • Sp1: emerging roles-beyond constitutive activation of TATA-less housekeeping genes
    • 10.1016/j.bbrc.2008.03.074, 18364237
    • Wierstra I. Sp1: emerging roles-beyond constitutive activation of TATA-less housekeeping genes. Biochem Biophys Res Commun 2008, 372:1-13. 10.1016/j.bbrc.2008.03.074, 18364237.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 1-13
    • Wierstra, I.1
  • 30
    • 0029878288 scopus 로고    scopus 로고
    • Induction of early growth response-1 gene by interleukin-1 beta and tumor necrosis factor-alpha in normal human bone marrow stromal an osteoblastic cells: regulation by a protein kinase C inhibitor
    • Chaudhary LR, Cheng SL, Avioli LV. Induction of early growth response-1 gene by interleukin-1 beta and tumor necrosis factor-alpha in normal human bone marrow stromal an osteoblastic cells: regulation by a protein kinase C inhibitor. Mol Cell Biochem 1996, 156:69-77.
    • (1996) Mol Cell Biochem , vol.156 , pp. 69-77
    • Chaudhary, L.R.1    Cheng, S.L.2    Avioli, L.V.3
  • 31
    • 0038381435 scopus 로고    scopus 로고
    • Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta
    • 10.1074/jbc.M301676200, 12637574
    • Tan L, Peng H, Osaki M, Choy BK, Auron PE, Sandell LJ, Goldring MB. Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta. J Biol Chem 2003, 278:17688-17700. 10.1074/jbc.M301676200, 12637574.
    • (2003) J Biol Chem , vol.278 , pp. 17688-17700
    • Tan, L.1    Peng, H.2    Osaki, M.3    Choy, B.K.4    Auron, P.E.5    Sandell, L.J.6    Goldring, M.B.7
  • 32
    • 77951183754 scopus 로고    scopus 로고
    • Transcription factor Egr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor alpha
    • 10.1158/1541-7786.MCR-09-0454, 20332214
    • Shin SY, Kim JH, Baker A, Lim Y, Lee YH. Transcription factor Egr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor alpha. Mol Cancer Res 2010, 8:507-519. 10.1158/1541-7786.MCR-09-0454, 20332214.
    • (2010) Mol Cancer Res , vol.8 , pp. 507-519
    • Shin, S.Y.1    Kim, J.H.2    Baker, A.3    Lim, Y.4    Lee, Y.H.5
  • 33
    • 60949089801 scopus 로고    scopus 로고
    • Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFalpha-induced MEK/ERK signalling
    • 10.1186/ar2595, 2688239, 19144181
    • Rockel JS, Bernier SM, Leask A. Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFalpha-induced MEK/ERK signalling. Arthritis Res Ther 2009, 11:R8. 10.1186/ar2595, 2688239, 19144181.
    • (2009) Arthritis Res Ther , vol.11
    • Rockel, J.S.1    Bernier, S.M.2    Leask, A.3
  • 34
    • 0028788227 scopus 로고
    • Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor A-chain promoter in cultured vascular endothelial cells
    • 10.1074/jbc.270.46.27679, 7499234
    • Khachigian LM, Williams AJ, Collins T. Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor A-chain promoter in cultured vascular endothelial cells. J Biol Chem 1995, 270:27679-27686. 10.1074/jbc.270.46.27679, 7499234.
    • (1995) J Biol Chem , vol.270 , pp. 27679-27686
    • Khachigian, L.M.1    Williams, A.J.2    Collins, T.3
  • 35
    • 35148883007 scopus 로고    scopus 로고
    • Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter
    • 10.1158/0008-5472.CAN-07-1525, 17909017
    • Zhang P, Tchou-Wong KM, Costa M. Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter. Cancer Res 2007, 67:9125-9133. 10.1158/0008-5472.CAN-07-1525, 17909017.
    • (2007) Cancer Res , vol.67 , pp. 9125-9133
    • Zhang, P.1    Tchou-Wong, K.M.2    Costa, M.3
  • 36
    • 33746925159 scopus 로고    scopus 로고
    • Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms
    • 10.1158/0008-5472.CAN-06-0346, 2610484, 16849552
    • Rong Y, Hu F, Huang R, Mackman N, Horowitz JM, Jensen RL, Durden DL, Van Meir EG, Brat DJ. Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Res 2006, 66:7067-7074. 10.1158/0008-5472.CAN-06-0346, 2610484, 16849552.
    • (2006) Cancer Res , vol.66 , pp. 7067-7074
    • Rong, Y.1    Hu, F.2    Huang, R.3    Mackman, N.4    Horowitz, J.M.5    Jensen, R.L.6    Durden, D.L.7    Van Meir, E.G.8    Brat, D.J.9
  • 37
    • 0036156038 scopus 로고    scopus 로고
    • Reciprocal regulation of beta(1)-adrenergic receptor gene transcription by Sp1 and early growth response gene 1: induction of EGR-1 inhibits the expression of the beta(1)-adrenergic receptor gene
    • 10.1124/mol.61.2.379, 11809863
    • Bahouth SW, Beauchamp MJ, Vu KN. Reciprocal regulation of beta(1)-adrenergic receptor gene transcription by Sp1 and early growth response gene 1: induction of EGR-1 inhibits the expression of the beta(1)-adrenergic receptor gene. Mol Pharmacol 2002, 61:379-390. 10.1124/mol.61.2.379, 11809863.
    • (2002) Mol Pharmacol , vol.61 , pp. 379-390
    • Bahouth, S.W.1    Beauchamp, M.J.2    Vu, K.N.3
  • 38
    • 0035816660 scopus 로고    scopus 로고
    • The reciprocal role of Egr-1 and Sp family proteins in regulation of the PTP1B promoter in response to the p210 Bcr-Abl oncoprotein-tyrosine kinase
    • 10.1074/jbc.M101354200, 11316810
    • Fukada T, Tonks NK. The reciprocal role of Egr-1 and Sp family proteins in regulation of the PTP1B promoter in response to the p210 Bcr-Abl oncoprotein-tyrosine kinase. J Biol Chem 2001, 276:25512-25519. 10.1074/jbc.M101354200, 11316810.
    • (2001) J Biol Chem , vol.276 , pp. 25512-25519
    • Fukada, T.1    Tonks, N.K.2
  • 39
    • 38049072314 scopus 로고    scopus 로고
    • Reciprocal regulation of the human sterol regulatory element binding protein (SREBP)-1a promoter by Sp1 and EGR-1 transcription factors
    • 10.1016/j.febslet.2007.11.083, 18068676
    • Fernandez-Alvarez A, Tur G, Lopez-Rodas G, Casado M. Reciprocal regulation of the human sterol regulatory element binding protein (SREBP)-1a promoter by Sp1 and EGR-1 transcription factors. FEBS Lett 2008, 582:177-184. 10.1016/j.febslet.2007.11.083, 18068676.
    • (2008) FEBS Lett , vol.582 , pp. 177-184
    • Fernandez-Alvarez, A.1    Tur, G.2    Lopez-Rodas, G.3    Casado, M.4
  • 40
    • 0037327335 scopus 로고    scopus 로고
    • Reciprocal regulation of expression of the human adenosine 5'-triphosphate binding cassette, sub-family A, transporter 2 (ABCA2) promoter by the early growth response-1 (EGR-1) and Sp-family transcription factors
    • 10.1093/nar/gkg192, 149212, 12560508
    • Davis WJ, Chen ZJ, Ile KE, Tew KD. Reciprocal regulation of expression of the human adenosine 5'-triphosphate binding cassette, sub-family A, transporter 2 (ABCA2) promoter by the early growth response-1 (EGR-1) and Sp-family transcription factors. Nucleic Acids Res 2003, 31:1097-1107. 10.1093/nar/gkg192, 149212, 12560508.
    • (2003) Nucleic Acids Res , vol.31 , pp. 1097-1107
    • Davis, W.J.1    Chen, Z.J.2    Ile, K.E.3    Tew, K.D.4
  • 41
    • 0032533527 scopus 로고    scopus 로고
    • Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1
    • 10.1172/JCI4561, 509135, 9819371
    • Srivastava S, Weitzmann MN, Kimble RB, Rizzo M, Zahner M, Milbrandt J, Ross FP, Pacifici R. Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1. J Clin Invest 1998, 102:1850-1859. 10.1172/JCI4561, 509135, 9819371.
    • (1998) J Clin Invest , vol.102 , pp. 1850-1859
    • Srivastava, S.1    Weitzmann, M.N.2    Kimble, R.B.3    Rizzo, M.4    Zahner, M.5    Milbrandt, J.6    Ross, F.P.7    Pacifici, R.8
  • 42
    • 0242497936 scopus 로고    scopus 로고
    • Specific interaction of Egr1 and c/EBPbeta leads to the transcriptional activation of the human low density lipoprotein receptor gene
    • 10.1074/jbc.M305564200, 12947119
    • Zhang F, Lin M, Abidi P, Thiel G, Liu J. Specific interaction of Egr1 and c/EBPbeta leads to the transcriptional activation of the human low density lipoprotein receptor gene. J Biol Chem 2003, 278:44246-44254. 10.1074/jbc.M305564200, 12947119.
    • (2003) J Biol Chem , vol.278 , pp. 44246-44254
    • Zhang, F.1    Lin, M.2    Abidi, P.3    Thiel, G.4    Liu, J.5
  • 43
    • 0028209305 scopus 로고
    • Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding protein
    • 358517, 8114696
    • Emili A, Greenblatt J, Ingles CJ. Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding protein. Mol Cell Biol 1994, 14:1582-1593. 358517, 8114696.
    • (1994) Mol Cell Biol , vol.14 , pp. 1582-1593
    • Emili, A.1    Greenblatt, J.2    Ingles, C.J.3
  • 44
    • 0030787557 scopus 로고    scopus 로고
    • Repression of the HSV-1 latency-associated transcript (LAT) promoter by the early growth response (EGR) proteins: involvement of a binding site immediately downstream of the TATA box
    • 10.3109/13550289709018296, 9200069
    • Tatarowicz WA, Martin CE, Pekosz AS, Madden SL, Rauscher F, Chiang SY, Beerman TA, Fraser NW. Repression of the HSV-1 latency-associated transcript (LAT) promoter by the early growth response (EGR) proteins: involvement of a binding site immediately downstream of the TATA box. J Neurovirol 1997, 3:212-224. 10.3109/13550289709018296, 9200069.
    • (1997) J Neurovirol , vol.3 , pp. 212-224
    • Tatarowicz, W.A.1    Martin, C.E.2    Pekosz, A.S.3    Madden, S.L.4    Rauscher, F.5    Chiang, S.Y.6    Beerman, T.A.7    Fraser, N.W.8
  • 45
    • 54049149754 scopus 로고    scopus 로고
    • NFkappaB mediates IL-1beta-induced down-regulation of TbetaRII through the modulation of Sp3 expression
    • 10.1111/j.1582-4934.2007.00173.x, 18053089
    • Bauge C, Beauchef G, Leclercq S, Kim SJ, Pujol JP, Galera P, Boumediene K. NFkappaB mediates IL-1beta-induced down-regulation of TbetaRII through the modulation of Sp3 expression. J Cell Mol Med 2008, 12:1754-1766. 10.1111/j.1582-4934.2007.00173.x, 18053089.
    • (2008) J Cell Mol Med , vol.12 , pp. 1754-1766
    • Bauge, C.1    Beauchef, G.2    Leclercq, S.3    Kim, S.J.4    Pujol, J.P.5    Galera, P.6    Boumediene, K.7
  • 46
    • 67650539080 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces caspase-mediated cleavage of peroxisome proliferator-activated receptor gamma in adipocytes
    • 10.1074/jbc.M809042200, 2719346, 19321447
    • Guilherme A, Tesz GJ, Guntur KV, Czech MP. Tumor necrosis factor-alpha induces caspase-mediated cleavage of peroxisome proliferator-activated receptor gamma in adipocytes. J Biol Chem 2009, 284:17082-17091. 10.1074/jbc.M809042200, 2719346, 19321447.
    • (2009) J Biol Chem , vol.284 , pp. 17082-17091
    • Guilherme, A.1    Tesz, G.J.2    Guntur, K.V.3    Czech, M.P.4
  • 47
    • 0036198010 scopus 로고    scopus 로고
    • Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia
    • 10.1016/S1534-5807(02)00131-4, 11879638
    • Yun Z, Maecker HL, Johnson RS, Giaccia AJ. Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia. Dev Cell 2002, 2:331-341. 10.1016/S1534-5807(02)00131-4, 11879638.
    • (2002) Dev Cell , vol.2 , pp. 331-341
    • Yun, Z.1    Maecker, H.L.2    Johnson, R.S.3    Giaccia, A.J.4
  • 48
    • 33645328290 scopus 로고    scopus 로고
    • Early growth response gene-1 expression in vascular smooth muscle cells effects of insulin and oxidant stress
    • 10.1016/j.amjhyper.2005.10.014, 16580571
    • Wang CC, Sharma G, Draznin B. Early growth response gene-1 expression in vascular smooth muscle cells effects of insulin and oxidant stress. Am J Hypertens 2006, 19:366-372. 10.1016/j.amjhyper.2005.10.014, 16580571.
    • (2006) Am J Hypertens , vol.19 , pp. 366-372
    • Wang, C.C.1    Sharma, G.2    Draznin, B.3
  • 49
    • 13244283238 scopus 로고    scopus 로고
    • Early growth response-1 regulates lipopolysaccharide-induced suppressor of cytokine signaling-1 transcription
    • Mostecki J, Showalter BM, Rothman PB. Early growth response-1 regulates lipopolysaccharide-induced suppressor of cytokine signaling-1 transcription. J Biol Chem 2005, 280:2596-2605.
    • (2005) J Biol Chem , vol.280 , pp. 2596-2605
    • Mostecki, J.1    Showalter, B.M.2    Rothman, P.B.3
  • 50
    • 33646381116 scopus 로고    scopus 로고
    • Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling
    • 10.1074/jbc.M506770200, 16439363
    • Cho SJ, Kang MJ, Homer RJ, Kang HR, Zhang X, Lee PJ, Elias JA, Lee CG. Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling. J Biol Chem 2006, 281:8161-8168. 10.1074/jbc.M506770200, 16439363.
    • (2006) J Biol Chem , vol.281 , pp. 8161-8168
    • Cho, S.J.1    Kang, M.J.2    Homer, R.J.3    Kang, H.R.4    Zhang, X.5    Lee, P.J.6    Elias, J.A.7    Lee, C.G.8
  • 51
    • 0037315381 scopus 로고    scopus 로고
    • Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression
    • 10.1093/nar/gkg186, 149206, 12560487
    • Decker EL, Nehmann N, Kampen E, Eibel H, Zipfel PF, Skerka C. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression. Nucleic Acids Res 2003, 31:911-921. 10.1093/nar/gkg186, 149206, 12560487.
    • (2003) Nucleic Acids Res , vol.31 , pp. 911-921
    • Decker, E.L.1    Nehmann, N.2    Kampen, E.3    Eibel, H.4    Zipfel, P.F.5    Skerka, C.6
  • 52
    • 33846259674 scopus 로고    scopus 로고
    • Early growth response 1 mediates the systemic and hepatic inflammatory response initiated by hemorrhagic shock
    • 10.1097/01.shk.0000245025.01365.8e, 17224790
    • Prince JM, Ming MJ, Levy RM, Liu S, Pinsky DJ, Vodovotz Y, Billiar TR. Early growth response 1 mediates the systemic and hepatic inflammatory response initiated by hemorrhagic shock. Shock 2007, 27:157-164. 10.1097/01.shk.0000245025.01365.8e, 17224790.
    • (2007) Shock , vol.27 , pp. 157-164
    • Prince, J.M.1    Ming, M.J.2    Levy, R.M.3    Liu, S.4    Pinsky, D.J.5    Vodovotz, Y.6    Billiar, T.R.7
  • 54
    • 0035199914 scopus 로고    scopus 로고
    • The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
    • 10.1038/ncb1201-1124, 11781575
    • Virolle T, Adamson ED, Baron V, Birle D, Mercola D, Mustelin T, de Belle I. The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling. Nat Cell Biol 2001, 3:1124-1128. 10.1038/ncb1201-1124, 11781575.
    • (2001) Nat Cell Biol , vol.3 , pp. 1124-1128
    • Virolle, T.1    Adamson, E.D.2    Baron, V.3    Birle, D.4    Mercola, D.5    Mustelin, T.6    de Belle, I.7
  • 55
    • 0032432868 scopus 로고    scopus 로고
    • Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis
    • 10.1002/1529-0131(199812)41:12<2165::AID-ART11>3.0.CO;2-O, 9870873
    • Melchiorri C, Meliconi R, Frizziero L, Silvestri T, Pulsatelli L, Mazzetti I, Borzi RM, Uguccioni M, Facchini A. Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis. Arthritis Rheum 1998, 41:2165-2174. 10.1002/1529-0131(199812)41:12<2165::AID-ART11>3.0.CO;2-O, 9870873.
    • (1998) Arthritis Rheum , vol.41 , pp. 2165-2174
    • Melchiorri, C.1    Meliconi, R.2    Frizziero, L.3    Silvestri, T.4    Pulsatelli, L.5    Mazzetti, I.6    Borzi, R.M.7    Uguccioni, M.8    Facchini, A.9
  • 56
    • 0026624810 scopus 로고
    • Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts
    • 10.1007/BF00300977, 1411083
    • Trabandt A, Aicher WK, Gay RE, Sukhatme VP, Fassbender HG, Gay S. Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts. Rheumatol Int 1992, 12:53-59. 10.1007/BF00300977, 1411083.
    • (1992) Rheumatol Int , vol.12 , pp. 53-59
    • Trabandt, A.1    Aicher, W.K.2    Gay, R.E.3    Sukhatme, V.P.4    Fassbender, H.G.5    Gay, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.