메뉴 건너뛰기




Volumn 7, Issue 1, 2013, Pages 28-36

Astrocyte signaling and neurodegeneration New insights into CNS disorders

Author keywords

Alzheimer disease; Amyotrophic lateral sclerosis; Astrocytes; Ca2+; Glutamate; Prion diseases

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CALCIUM ION; COPPER ZINC SUPEROXIDE DISMUTASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

EID: 84874606434     PISSN: 19336896     EISSN: 1933690X     Source Type: Journal    
DOI: 10.4161/pri.22512     Document Type: Conference Paper
Times cited : (56)

References (140)
  • 1
    • 23044435896 scopus 로고    scopus 로고
    • From brain glue to communication elements: The revolution continues
    • PMID:16025096
    • Volterra A, Meldolesi J. Astrocytes, from brain glue to communication elements: the revolution continues. Nat Rev Neurosci 2005; 6:626-40; PMID:16025096; http://dx.doi.org/10.1038/nrn1722.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 626-640
    • Volterra, A.1    Meldolesi, J.A.2
  • 2
    • 68049143450 scopus 로고    scopus 로고
    • Tripartite synapses: Astrocytes process and control synaptic information
    • PMID:19615761
    • Perea G, Navarrete M, Araque A. Tripartite synapses: astrocytes process and control synaptic information. Trends Neurosci 2009; 32:421-31; PMID:19615761; http://dx.doi.org/10.1016/j.tins.2009.05.001.
    • (2009) Trends Neurosci , vol.32 , pp. 421-431
    • Perea, G.1    Navarrete, M.2    Araque, A.3
  • 3
    • 77951929051 scopus 로고    scopus 로고
    • Integrated brain circuits: Astrocytic networks modulate neuronal activity and behavior
    • PMID:20148679
    • Halassa MM, Haydon PG. Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior. Annu Rev Physiol 2010; 72:335-55; PMID:20148679; http://dx.doi.org/10.1146/annurevphysiol-021909-135843.
    • (2010) Annu Rev Physiol , vol.72 , pp. 335-355
    • Halassa, M.M.1    Haydon, P.G.2
  • 4
    • 0015838278 scopus 로고
    • The activities of butyrylcholinesterase and carbonic anhydrase, the rate of anaerobic glycolysis, and the question of a constant density of glial cells in cerebral cortices of various mammalian species from mouse to whale
    • PMID:4633361
    • Tower DB, Young OM. The activities of butyrylcholinesterase and carbonic anhydrase, the rate of anaerobic glycolysis, and the question of a constant density of glial cells in cerebral cortices of various mammalian species from mouse to whale. J Neurochem 1973; 20:269-78; PMID:4633361; http://dx.doi.org/10. 1111/j.1471-4159.1973.tb12126.x.
    • (1973) J Neurochem , vol.20 , pp. 269-278
    • Tower, D.B.1    Young, O.M.2
  • 5
    • 79960784675 scopus 로고    scopus 로고
    • Implications of gliotransmission for the pharmacotherapy of CNS disorders
    • PMID:21790208
    • Rossi D, Martorana F, Brambilla L. Implications of gliotransmission for the pharmacotherapy of CNS disorders. CNS Drugs 2011; 25:641-58; PMID:21790208; http://dx.doi.org/10.2165/11593090-000000000-00000.
    • (2011) CNS Drugs , vol.25 , pp. 641-658
    • Rossi, D.1    Martorana, F.2    Brambilla, L.3
  • 6
    • 0036139877 scopus 로고    scopus 로고
    • Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains
    • PMID:11756501
    • Bushong EA, Martone ME, Jones YZ, Ellisman MH. Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. J Neurosci 2002; 22:183-92; PMID:11756501.
    • (2002) J Neurosci , vol.22 , pp. 183-192
    • Bushong, E.A.1    Martone, M.E.2    Jones, Y.Z.3    Ellisman, M.H.4
  • 7
    • 1342308184 scopus 로고    scopus 로고
    • Maturation of astrocyte morphology and the establishment of astrocyte domains during postnatal hippocampal development
    • PMID:15036382
    • Bushong EA, Martone ME, Ellisman MH. Maturation of astrocyte morphology and the establishment of astrocyte domains during postnatal hippocampal development. Int J Dev Neurosci 2004; 22:73-86; PMID:15036382; http://dx.doi.org/10.1016/j.ijdevneu.2003.12.008.
    • (2004) Int J Dev Neurosci , vol.22 , pp. 73-86
    • Bushong, E.A.1    Martone, M.E.2    Ellisman, M.H.3
  • 8
    • 34250317399 scopus 로고    scopus 로고
    • Synaptic islands defined by the territory of a single astrocyte
    • PMID:17567808
    • Halassa MM, Fellin T, Takano H, Dong JH, Haydon PG. Synaptic islands defined by the territory of a single astrocyte. J Neurosci 2007; 27:6473- 7; PMID:17567808; http://dx.doi.org/10.1523/JNEUROSCI.1419-07.2007.
    • (2007) J Neurosci , vol.27 , pp. 6473-6477
    • Halassa, M.M.1    Fellin, T.2    Takano, H.3    Dong, J.H.4    Haydon, P.G.5
  • 10
    • 80052419916 scopus 로고    scopus 로고
    • Role of astrocytes in neurovascular coupling
    • PMID:21903073
    • Petzold GC, Murthy VN. Role of astrocytes in neurovascular coupling. Neuron 2011; 71:782-97; PMID:21903073; http://dx.doi.org/10.1016/j.neuron.2011. 08.009.
    • (2011) Neuron , vol.71 , pp. 782-797
    • Petzold, G.C.1    Murthy, V.N.2
  • 11
    • 82955168362 scopus 로고    scopus 로고
    • Brain energy metabolism: Focus on astrocyte-neuron metabolic cooperation
    • PMID:22152301
    • Bélanger M, Allaman I, Magistretti PJ. Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. Cell Metab 2011; 14:724-38; PMID:22152301; http://dx.doi.org/10.1016/j.cmet.2011.08.016.
    • (2011) Cell Metab , vol.14 , pp. 724-738
    • Bélanger, M.1    Allaman, I.2    Magistretti, P.J.3
  • 12
    • 79961175318 scopus 로고    scopus 로고
    • The neurovascular link in health and disease: Molecular mechanisms and therapeutic implications
    • Quaegebeur A, Lange C, Carmeliet P. The neurovascular link in health and disease: molecular mechanisms and therapeutic implications. Neuron 2011; 71:406- 24; PMID:21835339; http://dx.doi.org/10.1016/j.neuron.2011.07.013.
    • (2011) Neuron , vol.71 , pp. 406-424
    • Quaegebeur, A.1    Lange, C.2    Carmeliet, P.3
  • 13
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • PMID:11369436
    • Danbolt NC. Glutamate uptake. Prog Neurobiol 2001; 65:1-105; PMID:11369436; http://dx.doi.org/10.1016/S0301-0082(00)00067-8.
    • (2001) Prog Neurobiol , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 14
    • 9344266325 scopus 로고    scopus 로고
    • Potassium buffering in the central nervous system
    • PMID:15561419
    • Kofuji P, Newman EA. Potassium buffering in the central nervous system. Neuroscience 2004; 129:1045-56; PMID:15561419; http://dx.doi.org/10.1016/j. neuroscience.2004.06.008.
    • (2004) Neuroscience , vol.129 , pp. 1045-1056
    • Kofuji, P.1    Newman, E.A.2
  • 15
    • 9344248393 scopus 로고    scopus 로고
    • The neurobiology of glia in the context of water and ion homeostasis
    • PMID:15561405
    • Simard M, Nedergaard M. The neurobiology of glia in the context of water and ion homeostasis. Neuroscience 2004; 129:877-96; PMID:15561405; http://dx.doi.org/10.1016/j.neuroscience.2004.09.053.
    • (2004) Neuroscience , vol.129 , pp. 877-896
    • Simard, M.1    Nedergaard, M.2
  • 16
    • 0033135292 scopus 로고    scopus 로고
    • Haydon PG. Tripartite synapses: Glia, the unacknowledged partner
    • PMID:10322493
    • Araque A, Parpura V, Sanzgiri RP, Haydon PG. Tripartite synapses: glia, the unacknowledged partner. Trends Neurosci 1999; 22:208-15; PMID:10322493; http://dx.doi.org/10.1016/S0166-2236(98)01349-6.
    • (1999) Trends Neurosci , vol.22 , pp. 208-215
    • Araque, A.1    Parpura, V.2    Sanzgiri, R.P.3
  • 18
    • 0025138986 scopus 로고
    • Glutamate induces calcium waves in cultured astrocytes: Long-range glial signaling
    • PMID:1967852
    • Cornell-Bell AH, Finkbeiner SM, Cooper MS, Smith SJ. Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling. Science 1990; 247:470-3; PMID:1967852; http://dx.doi.org/10.1126/science.1967852.
    • (1990) Science , vol.247 , pp. 470-473
    • Cornell-Bell, A.H.1    Finkbeiner, S.M.2    Cooper, M.S.3    Smith, S.J.4
  • 19
    • 0034743201 scopus 로고    scopus 로고
    • Spontaneous astrocytic Ca2+ oscillations in situ drive NMDAR-mediated neuronal excitation
    • PMID:11477426
    • Parri HR, Gould TM, Crunelli V. Spontaneous astrocytic Ca2+ oscillations in situ drive NMDAR-mediated neuronal excitation. Nat Neurosci 2001; 4:803-12; PMID:11477426; http://dx.doi.org/10.1038/90507.
    • (2001) Nat Neurosci , vol.4 , pp. 803-812
    • Parri, H.R.1    Gould, T.M.2    Crunelli, V.3
  • 20
    • 0036082850 scopus 로고    scopus 로고
    • Hippocampal astrocytes in situ exhibit calcium oscillations that occur independent of neuronal activity
    • PMID:11784768
    • Nett WJ, Oloff SH, McCarthy KD. Hippocampal astrocytes in situ exhibit calcium oscillations that occur independent of neuronal activity. J Neurophysiol 2002; 87:528-37; PMID:11784768.
    • (2002) J Neurophysiol , vol.87 , pp. 528-537
    • Nett, W.J.1    Oloff, S.H.2    McCarthy, K.D.3
  • 21
    • 0036851001 scopus 로고    scopus 로고
    • Neuronal activity regulates correlated network properties of spontaneous calcium transients in astrocytes in situ
    • PMID:12417668
    • Aguado F, Espinosa-Parrilla JF, Carmona MA, Soriano E. Neuronal activity regulates correlated network properties of spontaneous calcium transients in astrocytes in situ. J Neurosci 2002; 22:9430-44; PMID:12417668.
    • (2002) J Neurosci , vol.22 , pp. 9430-9444
    • Aguado, F.1    Espinosa-Parrilla, J.F.2    Carmona, M.A.3    Soriano, E.4
  • 22
    • 19344362473 scopus 로고    scopus 로고
    • Calcium dynamics of cortical astrocytic networks in vivo
    • PMID:15094801
    • Hirase H, Qian L, Barthó P, Buzsáki G. Calcium dynamics of cortical astrocytic networks in vivo. PLoS Biol 2004; 2:E96; PMID:15094801; http://dx.doi.org/10.1371/journal.pbio.0020096.
    • (2004) PLoS Biol , vol.2
    • Hirase, H.1    Qian, L.2    Barthó, P.3    Buzsáki, G.4
  • 23
    • 18744409106 scopus 로고    scopus 로고
    • Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
    • PMID:15782150
    • Nimmerjahn A, Kirchhoff F, Kerr JN, Helmchen F. Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat Methods 2004; 1:31-7; PMID:15782150; http://dx.doi.org/10.1038/nmeth706.
    • (2004) Nat Methods , vol.1 , pp. 31-37
    • Nimmerjahn, A.1    Kirchhoff, F.2    Kerr, J.N.3    Helmchen, F.4
  • 24
    • 0026503603 scopus 로고
    • Neuronal activity triggers calcium waves in hippocampal astrocyte networks
    • PMID:1347996
    • Dani JW, Chernjavsky A, Smith SJ. Neuronal activity triggers calcium waves in hippocampal astrocyte networks. Neuron 1992; 8:429-40; PMID:1347996; http://dx.doi.org/10.1016/0896-6273(92)90271-E.
    • (1992) Neuron , vol.8 , pp. 429-440
    • Dani, J.W.1    Chernjavsky, A.2    Smith, S.J.3
  • 25
    • 0027162790 scopus 로고
    • Rapid communication between neurons and astrocytes in primary cortical cultures
    • PMID:8501531
    • Murphy TH, Blatter LA, Wier WG, Baraban JM. Rapid communication between neurons and astrocytes in primary cortical cultures. J Neurosci 1993; 13:2672- 9; PMID:8501531.
    • (1993) J Neurosci , vol.13 , pp. 2672-2679
    • Murphy, T.H.1    Blatter, L.A.2    Wier, W.G.3    Baraban, J.M.4
  • 26
    • 0030820823 scopus 로고    scopus 로고
    • Intracellular calcium oscillations in astrocytes: A highly plastic, bidirectional form of communication between neurons and astrocytes in situ
    • PMID:9315902
    • Pasti L, Volterra A, Pozzan T, Carmignoto G. Intracellular calcium oscillations in astrocytes: a highly plastic, bidirectional form of communication between neurons and astrocytes in situ. J Neurosci 1997; 17:7817-30; PMID:9315902.
    • (1997) J Neurosci , vol.17 , pp. 7817-7830
    • Pasti, L.1    Volterra, A.2    Pozzan, T.3    Carmignoto, G.4
  • 27
    • 0029240256 scopus 로고
    • GFAP-positive hippocampal astrocytes in situ respond to glutamatergic neuroligands with increases in [Ca2+]i
    • PMID:7544323
    • Porter JT, McCarthy KD. GFAP-positive hippocampal astrocytes in situ respond to glutamatergic neuroligands with increases in [Ca2+]i. Glia 1995; 13:101- 12; PMID:7544323; http://dx.doi.org/10.1002/glia.440130204.
    • (1995) Glia , vol.13 , pp. 101-112
    • Porter, J.T.1    McCarthy, K.D.2
  • 28
    • 0029081246 scopus 로고
    • Adenosine receptors modulate [Ca2+]i in hippocampal astrocytes in situ
    • PMID:7561845
    • Porter JT, McCarthy KD. Adenosine receptors modulate [Ca2+]i in hippocampal astrocytes in situ. J Neurochem 1995; 65:1515-23; PMID:7561845; http://dx.doi.org/10.1046/j.1471-4159.1995.65041515.x.
    • (1995) J Neurochem , vol.65 , pp. 1515-1523
    • Porter, J.T.1    McCarthy, K.D.2
  • 29
    • 0029758991 scopus 로고    scopus 로고
    • Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals
    • PMID:8756437
    • Porter JT, McCarthy KD. Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals. J Neurosci 1996; 16:5073-81; PMID:8756437.
    • (1996) J Neurosci , vol.16 , pp. 5073-5081
    • Porter, J.T.1    McCarthy, K.D.2
  • 30
    • 0034744282 scopus 로고    scopus 로고
    • Differential mechanisms of Ca2+ responses in glial cells evoked by exogenous and endogenous glutamate in rat hippocampus
    • PMID:11345120
    • Latour I, Gee CE, Robitaille R, Lacaille JC.Differential mechanisms of Ca2+ responses in glial cells evoked by exogenous and endogenous glutamate in rat hippocampus. Hippocampus 2001; 11:132- 45; PMID:11345120; http://dx.doi.org/10.1002/hipo.1031.
    • (2001) Hippocampus , vol.11 , pp. 132-145
    • Latour, I.1    Gee, C.E.2    Robitaille, R.3    Lacaille, J.C.4
  • 31
    • 33847183442 scopus 로고    scopus 로고
    • Glutamate exocytosis from astrocytes controls synaptic strength
    • PMID:17310248
    • Jourdain P, Bergersen LH, Bhaukaurally K, Bezzi P, Santello M, Domercq M, et al. Glutamate exocytosis from astrocytes controls synaptic strength. Nat Neurosci 2007; 10:331-9; PMID:17310248; http://dx.doi.org/10.1038/nn1849.
    • (2007) Nat Neurosci , vol.10 , pp. 331-339
    • Jourdain, P.1    Bergersen, L.H.2    Bhaukaurally, K.3    Bezzi, P.4    Santello, M.5    Domercq, M.6
  • 32
    • 79952234841 scopus 로고    scopus 로고
    • TNFα controls glutamatergic gliotransmission in the hippocampal dentate gyrus
    • PMID:21382557
    • Santello M, Bezzi P, Volterra A. TNFα controls glutamatergic gliotransmission in the hippocampal dentate gyrus. Neuron 2011; 69:988-1001; PMID:21382557; http://dx.doi.org/10.1016/j.neuron.2011.02.003.
    • (2011) Neuron , vol.69 , pp. 988-1001
    • Santello, M.1    Bezzi, P.2    Volterra, A.3
  • 33
    • 80053258053 scopus 로고    scopus 로고
    • Local Ca2+ detection and modulation of synaptic release by astrocytes
    • PMID:21909085
    • Di Castro MA, Chuquet J, Liaudet N, Bhaukaurally K, Santello M, Bouvier D, et al. Local Ca2+ detection and modulation of synaptic release by astrocytes. Nat Neurosci 2011; 14:1276-84; PMID:21909085; http://dx.doi.org/10.1038/nn. 2929.
    • (2011) Nat Neurosci , vol.14 , pp. 1276-1284
    • Di Casyro, M.A.1    Chuquet, J.2    Liaudet, N.3    Bhaukaurally, K.4    Santello, M.5    Bouvier, D.6
  • 34
    • 33745712926 scopus 로고    scopus 로고
    • Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo
    • PMID:16699507
    • Wang X, Lou N, Xu Q, Tian GF, Peng WG, Han X, et al. Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo. Nat Neurosci 2006; 9:816-23; PMID:16699507; http://dx.doi.org/10.1038/nn1703.
    • (2006) Nat Neurosci , vol.9 , pp. 816-823
    • Wang, X.1    Lou, N.2    Xu, Q.3    Tian, G.F.4    Peng, W.G.5    Han, X.6
  • 35
    • 34249980900 scopus 로고    scopus 로고
    • Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo
    • PMID:17554000
    • Winship IR, Plaa N, Murphy TH. Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo. J Neurosci 2007; 27:6268-72; PMID:17554000; http://dx.doi.org/10.1523/JNEUROSCI.4801-06. 2007.
    • (2007) J Neurosci , vol.27 , pp. 6268-6272
    • Winship, I.R.1    Plaa, N.2    Murphy, T.H.3
  • 36
    • 0032742779 scopus 로고    scopus 로고
    • Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells
    • PMID:10512979
    • Sanzgiri RP, Araque A, Haydon PG. Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. J Neurobiol 1999; 41:221-9; PMID:10512979; http://dx.doi.org/10.1002/(SICI)1097- 4695(19991105)41:2<221::AID-NEU5>3.0.CO;2-A.
    • (1999) J Neurobiol , vol.41 , pp. 221-229
    • Sanzgiri, R.P.1    Araque, A.2    Haydon, P.G.3
  • 37
    • 0035052896 scopus 로고    scopus 로고
    • ATP stimulates calcium-dependent glutamate release from cultured astrocytes
    • PMID:11299329
    • Jeremic A, Jeftinija K, Stevanovic J, Glavaski A, Jeftinija S. ATP stimulates calcium-dependent glutamate release from cultured astrocytes. J Neurochem 2001; 77:664-75; PMID:11299329; http://dx.doi.org/10.1046/j.1471-4159. 2001.00272.x.
    • (2001) J Neurochem , vol.77 , pp. 664-675
    • Jeremic, A.1    Jeftinija, K.2    Stevanovic, J.3    Glavaski, A.4    Jeftinija, S.5
  • 38
    • 0034960228 scopus 로고    scopus 로고
    • CXCR4-activated astrocyte glutamate release via TNFalpha: Amplification by microglia triggers neurotoxicity
    • PMID:11426226
    • Bezzi P, Domercq M, Brambilla L, Galli R, Schols D, De Clercq E, et al. CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nat Neurosci 2001; 4:702-10; PMID:11426226; http://dx.doi.org/10.1038/89490.
    • (2001) Nat Neurosci , vol.4 , pp. 702-710
    • Bezzi, P.1    Domercq, M.2    Brambilla, L.3    Galli, R.4    Schols, D.5    De Clercq, E.6
  • 39
    • 28044461306 scopus 로고    scopus 로고
    • Receptor-mediated glutamate release from volume sensitive channels in astrocytes
    • PMID:16254051
    • Takano T, Kang J, Jaiswal JK, Simon SM, Lin JH, Yu Y, et al. Receptor-mediated glutamate release from volume sensitive channels in astrocytes. Proc Natl Acad Sci U S A 2005; 102:16466-71; PMID:16254051; http://dx.doi.org/10.1073/pnas.0506382102.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 16466-16471
    • Takano, T.1    Kang, J.2    Jaiswal, J.K.3    Simon, S.M.4    Lin, J.H.5    Yu, Y.6
  • 40
    • 28044436908 scopus 로고    scopus 로고
    • Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons
    • PMID:16162834
    • Kang N, Xu J, Xu Q, Nedergaard M, Kang J. Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons. J Neurophysiol 2005; 94:4121- 30; PMID:16162834; http://dx.doi.org/10.1152/jn.00448.2005.
    • (2005) J Neurophysiol , vol.94 , pp. 4121-4130
    • Kang, N.1    Xu, J.2    Xu, Q.3    Nedergaard, M.4    Kang, J.5
  • 41
    • 3843109172 scopus 로고    scopus 로고
    • Glutamate released from glial cells synchronizes neuronal activity in the hippocampus
    • PMID:15295027
    • Angulo MC, Kozlov AS, Charpak S, Audinat E. Glutamate released from glial cells synchronizes neuronal activity in the hippocampus. J Neurosci 2004; 24:6920-7; PMID:15295027; http://dx.doi.org/10.1523/JNEUROSCI.0473-04.2004.
    • (2004) J Neurosci , vol.24 , pp. 6920-6927
    • Angulo, M.C.1    Kozlov, A.S.2    Charpak, S.3    Audinat, E.4
  • 42
    • 4444320120 scopus 로고    scopus 로고
    • Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors
    • PMID:15339653
    • Fellin T, Pascual O, Gobbo S, Pozzan T, Haydon PG, Carmignoto G. Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors. Neuron 2004; 43:729-43; PMID:15339653; http://dx.doi.org/10. 1016/j.neuron.2004.08.011.
    • (2004) Neuron , vol.43 , pp. 729-743
    • Fellin, T.1    Pascual, O.2    Gobbo, S.3    Pozzan, T.4    Haydon, P.G.5    Carmignoto, G.6
  • 43
    • 14644388122 scopus 로고    scopus 로고
    • Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes
    • PMID:15745945
    • Perea G, Araque A. Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes. J Neurosci 2005; 25:2192- 203; PMID:15745945; http://dx.doi.org/10.1523/JNEUROSCI.3965-04.2005.
    • (2005) J Neurosci , vol.25 , pp. 2192-2203
    • Perea, G.1    Araque, A.2
  • 45
    • 40849100074 scopus 로고    scopus 로고
    • Endocannabinoids mediate neuron-astrocyte communication
    • PMID:18367089
    • Navarrete M, Araque A. Endocannabinoids mediate neuron-astrocyte communication. Neuron 2008; 57:883-93; PMID:18367089; http://dx.doi.org/10.1016/ j.neuron.2008.01.029.
    • (2008) Neuron , vol.57 , pp. 883-893
    • Navarrete, M.1    Araque, A.2
  • 46
    • 48549083976 scopus 로고    scopus 로고
    • Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons
    • PMID:18579739
    • Shigetomi E, Bowser DN, Sofroniew MV, Khakh BS. Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons. J Neurosci 2008; 28:6659-63; PMID:18579739; http://dx.doi.org/10.1523/JNEUROSCI.1717-08.2008.
    • (2008) J Neurosci , vol.28 , pp. 6659-6663
    • Shigetomi, E.1    Bowser, D.N.2    Sofroniew, M.V.3    Khakh, B.S.4
  • 47
    • 74549135360 scopus 로고    scopus 로고
    • Long-term potentiation depends on release of D-serine from astrocytes
    • PMID:20075918
    • Henneberger C, Papouin T, Oliet SH, Rusakov DA. Long-term potentiation depends on release of D-serine from astrocytes. Nature 2010; 463:232- 6; PMID:20075918; http://dx.doi.org/10.1038/nature08673.
    • (2010) Nature , vol.463 , pp. 232-236
    • Henneberger, C.1    Papouin, T.2    Oliet, S.H.3    Rusakov, D.A.4
  • 48
    • 58549112040 scopus 로고    scopus 로고
    • Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss
    • PMID:19186164
    • Halassa MM, Florian C, Fellin T, Munoz JR, Lee SY, Abel T, et al. Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss. Neuron 2009; 61:213-9; PMID:19186164; http://dx.doi.org/10.1016/j.neuron. 2008.11.024.
    • (2009) Neuron , vol.61 , pp. 213-219
    • Halassa, M.M.1    Florian, C.2    Fellin, T.3    Munoz, J.R.4    Lee, S.Y.5    Abel, T.6
  • 49
    • 77955105496 scopus 로고    scopus 로고
    • Astrocytes control breathing through pH-dependent release of ATP
    • PMID:20647426
    • Gourine AV, Kasymov V, Marina N, Tang F, Figueiredo MF, Lane S, et al. Astrocytes control breathing through pH-dependent release of ATP. Science 2010; 329:571- 5; PMID:20647426; http://dx.doi.org/10.1126/science.1190721.
    • (2010) Science , vol.329 , pp. 571-575
    • Gourine, A.V.1    Kasymov, V.2    Marina, N.3    Tang, F.4    Figueiredo, M.F.5    Lane, S.6
  • 50
    • 77949678204 scopus 로고    scopus 로고
    • Glia contribute to the purinergic modulation of inspiratory rhythmgenerating networks
    • PMID:20237265
    • Huxtable AG, Zwicker JD, Alvares TS, Ruangkittisakul A, Fang X, Hahn LB, et al. Glia contribute to the purinergic modulation of inspiratory rhythmgenerating networks. J Neurosci 2010; 30:3947- 58; PMID:20237265; http://dx.doi.org/10.1523/JNEUROSCI.6027-09.2010.
    • (2010) J Neurosci , vol.30 , pp. 3947-3958
    • Huxtable, A.G.1    Zwicker, J.D.2    Alvares, T.S.3    Ruangkittisakul, A.4    Fang, X.5    Hahn, L.B.6
  • 51
    • 0032518514 scopus 로고    scopus 로고
    • Prostaglandins stimulate calciumdependent glutamate release in astrocytes
    • PMID:9440691
    • Bezzi P, Carmignoto G, Pasti L, Vesce S, Rossi D, Rizzini BL, et al. Prostaglandins stimulate calciumdependent glutamate release in astrocytes. Nature 1998; 391:281-5; PMID:9440691; http://dx.doi.org/10.1038/34651.
    • (1998) Nature , vol.391 , pp. 281-285
    • Bezzi, P.1    Carmignoto, G.2    Pasti, L.3    Vesce, S.4    Rossi, D.5    Rizzini, B.L.6
  • 52
    • 33750052586 scopus 로고    scopus 로고
    • P2Y1 receptor-evoked glutamate exocytosis from astrocytes: Control by tumor necrosis factor-alpha and prostaglandins
    • PMID:16882655
    • Domercq M, Brambilla L, Pilati E, Marchaland J, Volterra A, Bezzi P. P2Y1 receptor-evoked glutamate exocytosis from astrocytes: control by tumor necrosis factor-alpha and prostaglandins. J Biol Chem 2006; 281:30684-96; PMID:16882655; http://dx.doi.org/10.1074/jbc.M606429200.
    • (2006) J Biol Chem , vol.281 , pp. 30684-30696
    • Domercq, M.1    Brambilla, L.2    Pilati, E.3    Marchaland, J.4    Volterra, A.5    Bezzi, P.6
  • 53
    • 34247231421 scopus 로고    scopus 로고
    • Two forms of single-vesicle astrocyte exocytosis imaged with total internal reflection fluorescence microscopy
    • PMID:17360502
    • Bowser DN, Khakh BS. Two forms of single-vesicle astrocyte exocytosis imaged with total internal reflection fluorescence microscopy. Proc Natl Acad Sci U S A 2007; 104:4212-7; PMID:17360502; http://dx.doi.org/10.1073/pnas. 0607625104.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4212-4217
    • Bowser, D.N.1    Khakh, B.S.2
  • 54
    • 47249112916 scopus 로고    scopus 로고
    • SDF 1-alpha (CXCL12) triggers glutamate exocytosis from astrocytes on a millisecond time scale: Imaging analysis at the single-vesicle level with TIRF microscopy
    • PMID:18538866
    • Calì C, Marchaland J, Regazzi R, Bezzi P. SDF 1-alpha (CXCL12) triggers glutamate exocytosis from astrocytes on a millisecond time scale: imaging analysis at the single-vesicle level with TIRF microscopy. J Neuroimmunol 2008; 198:82-91; PMID:18538866; http://dx.doi.org/10.1016/j. jneuroim.2008.04.015.
    • (2008) J Neuroimmunol , vol.198 , pp. 82-91
    • Calì, C.1    Marchaland, J.2    Regazzi, R.3    Bezzi, P.4
  • 55
    • 0027314268 scopus 로고
    • Molecular profile of reactive astrocytes-implications for their role in neurologic disease
    • PMID:8515840
    • Eddleston M, Mucke L. Molecular profile of reactive astrocytes- implications for their role in neurologic disease. Neuroscience 1993; 54:15-36; PMID:8515840; http://dx.doi.org/10.1016/0306-4522(93)90380-X.
    • (1993) Neuroscience , vol.54 , pp. 15-36
    • Eddleston, M.1    Mucke, L.2
  • 56
    • 0030697366 scopus 로고    scopus 로고
    • Reactive astrocytes: Cellular and molecular cues to biological function
    • PMID:9416670
    • Ridet JL, Malhotra SK, Privat A, Gage FH. Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 1997; 20:570-7; PMID:9416670; http://dx.doi.org/10.1016/S0166-2236(97)01139-9.
    • (1997) Trends Neurosci , vol.20 , pp. 570-577
    • Ridet, J.L.1    Malhotra, S.K.2    Privat, A.3    Gage, F.H.4
  • 57
    • 0037465548 scopus 로고    scopus 로고
    • Death receptors on reactive astrocytes: A key role in the fine tuning of brain inflammation?
    • PMID:12607528
    • Dietrich PY, Walker PR, Saas P. Death receptors on reactive astrocytes: a key role in the fine tuning of brain inflammation? Neurology 2003; 60:548- 54; PMID:12607528; http://dx.doi.org/10.1212/01.WNL.0000042049.74547.7F.
    • (2003) Neurology , vol.60 , pp. 548-554
    • Dietrich, P.Y.1    Walker, P.R.2    Saas, P.3
  • 58
    • 54049106867 scopus 로고    scopus 로고
    • Focal degeneration of astrocytes in amyotrophic lateral sclerosis
    • PMID:18617894
    • Rossi D, Brambilla L, Valori CF, Roncoroni C, Crugnola A, Yokota T, et al. Focal degeneration of astrocytes in amyotrophic lateral sclerosis. Cell Death Differ 2008; 15:1691-700; PMID:18617894; http://dx.doi.org/10.1038/cdd. 2008.99.
    • (2008) Cell Death Differ , vol.15 , pp. 1691-1700
    • Rossi, D.1    Brambilla, L.2    Valori, C.F.3    Roncoroni, C.4    Crugnola, A.5    Yokota, T.6
  • 59
    • 84856331327 scopus 로고    scopus 로고
    • The BH4 domain of Bcl-X(L) rescues astrocyte degeneration in amyotrophic lateral sclerosis by modulating intracellular calcium signals
    • PMID:22072391
    • Martorana F, Brambilla L, Valori CF, Bergamaschi C, Roncoroni C, Aronica E, et al. The BH4 domain of Bcl-X(L) rescues astrocyte degeneration in amyotrophic lateral sclerosis by modulating intracellular calcium signals. Hum Mol Genet 2012; 21:826-40; PMID:22072391; http://dx.doi.org/10.1093/hmg/ddr513.
    • (2012) Hum Mol Genet , vol.21 , pp. 826-840
    • Martorana, F.1    Brambilla, L.2    Valori, C.F.3    Bergamaschi, C.4    Roncoroni, C.5    Aronica, E.6
  • 60
    • 34250725402 scopus 로고    scopus 로고
    • Mitochondrial Ca2+ as a key regulator of cell life and death
    • PMID:17431419
    • Giacomello M, Drago I, Pizzo P, Pozzan T. Mitochondrial Ca2+ as a key regulator of cell life and death. Cell Death Differ 2007; 14:1267-74; PMID:17431419; http://dx.doi.org/10.1038/sj.cdd.4402147.
    • (2007) Cell Death Differ , vol.14 , pp. 1267-1274
    • Giacomello, M.1    Drago, I.2    Pizzo, P.3    Pozzan, T.4
  • 61
    • 34247480926 scopus 로고    scopus 로고
    • IP3 receptors in cell survival and apoptosis: Ca2+ release and beyond
    • PMID:17294082
    • Joseph SK, Hajnóczky G. IP3 receptors in cell survival and apoptosis: Ca2+ release and beyond. Apoptosis 2007; 12:951-68; PMID:17294082; http://dx.doi.org/10.1007/s10495-007-0719-7.
    • (2007) Apoptosis , vol.12 , pp. 951-968
    • Joseph, S.K.1    Hajnóczky, G.2
  • 62
    • 0038464650 scopus 로고    scopus 로고
    • Regulation of cell death: The calcium-apoptosis link
    • PMID:12838338
    • Orrenius S, Zhivotovsky B, Nicotera P. Regulation of cell death: the calcium-apoptosis link. Nat Rev Mol Cell Biol 2003; 4:552-65; PMID:12838338; http://dx.doi.org/10.1038/nrm1150.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 552-565
    • Orrenius, S.1    Zhivotovsky, B.2    Nicotera, P.3
  • 63
    • 54949110895 scopus 로고    scopus 로고
    • Alcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis
    • C, PMID:18955969
    • Pinton P, Giorgi C, Siviero R, Zecchini E, Rizzuto R. Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis. Oncogene 2008; 27:6407-18; PMID:18955969; http://dx.doi.org/10.1038/onc.2008.308.
    • (2008) Oncogene , vol.27 , pp. 6407-6418
    • Pinton, P.1    Giorgi, C.2    Siviero, R.3    Zecchini, E.4    Rizzuto, R.5
  • 64
    • 74049164709 scopus 로고    scopus 로고
    • Noncell autonomous toxicity in neurodegenerative disorders: ALS and beyond
    • PMID:19951898
    • Ilieva H, Polymenidou M, Cleveland DW. Noncell autonomous toxicity in neurodegenerative disorders: ALS and beyond. J Cell Biol 2009; 187:761- 72; PMID:19951898; http://dx.doi.org/10.1083/jcb.200908164.
    • (2009) J Cell Biol , vol.187 , pp. 761-772
    • Ilieva, H.1    Polymenidou, M.2    Cleveland, D.W.3
  • 65
    • 33746310315 scopus 로고    scopus 로고
    • Alzheimer's disease
    • PMID:16876668
    • Blennow K, de Leon MJ, Zetterberg H. Alzheimer's disease. Lancet 2006; 368:387-403; PMID:16876668; http://dx.doi.org/10.1016/S0140-6736(06)69113-7.
    • (2006) Lancet , vol.368 , pp. 387-403
    • Blennow, K.1    De Leon, M.J.2    Zetterberg, H.3
  • 66
    • 33748471099 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease: Driving force, bystander or beneficial response?
    • PMID:16960575
    • Wyss-Coray T. Inflammation in Alzheimer disease: driving force, bystander or beneficial response? Nat Med 2006; 12:1005-15; PMID:16960575.
    • (2006) Nat Med , vol.12 , pp. 1005-1015
    • Wyss-Coray, T.1
  • 67
    • 75149118999 scopus 로고    scopus 로고
    • Neuroinflammation in Alzheimer's disease and mild cognitive impairment: A field in its infancy
    • PMID:20061650
    • McGeer EG, McGeer PL. Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy. J Alzheimers Dis 2010; 19:355-61; PMID:20061650.
    • (2010) J Alzheimers Dis , vol.19 , pp. 355-61
    • Mcgeer, E.G.1    Mcgeer, P.L.2
  • 68
    • 27744482552 scopus 로고    scopus 로고
    • Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein- 1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice
    • PMID:16232318
    • Janelsins MC, Mastrangelo MA, Oddo S, LaFerla FM, Federoff HJ, Bowers WJ. Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein- 1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. J Neuroinflammation 2005; 2:23; PMID:16232318; http://dx.doi.org/10.1186/1742- 2094-2-23.
    • (2005) J Neuroinflammation , vol.2 , pp. 23
    • Janelsins, M.C.1    Mastrangelo, M.A.2    Oddo, S.3    Laferla, F.M.4    Federoff, H.J.5    Bowers, W.J.6
  • 69
    • 0036949091 scopus 로고    scopus 로고
    • Local neuroinflammation and the progression of Alzheimer's disease
    • PMID:12476347
    • McGeer PL, McGeer EG. Local neuroinflammation and the progression of Alzheimer's disease. J Neurovirol 2002; 8:529-38; PMID:12476347; http://dx.doi.org/10.1080/13550280290100969.
    • (2002) J Neurovirol , vol.8 , pp. 529-538
    • Mcgeer, P.L.1    McGeer, E.G.2
  • 70
    • 68949205705 scopus 로고    scopus 로고
    • Tumour necrosis factor modulation for treatment of Alzheimer's disease: Rationale and current evidence
    • PMID:19689163
    • Tobinick E. Tumour necrosis factor modulation for treatment of Alzheimer's disease: rationale and current evidence. CNS Drugs 2009; 23:713-25; PMID:19689163; http://dx.doi.org/10.2165/11310810-000000000-00000.
    • (2009) CNS Drugs , vol.23 , pp. 713-725
    • Tobinick, E.1
  • 71
    • 34547252566 scopus 로고    scopus 로고
    • Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: Function-based and target-based discovery approaches
    • PMID:17678967
    • Van Eldik LJ, Thompson WL, Ralay Ranaivo H, Behanna HA, Martin Watterson D. Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: function-based and target-based discovery approaches. Int Rev Neurobiol 2007; 82:277-96; PMID:17678967; http://dx.doi.org/10.1016/S0074-7742(07)82015-0.
    • (2007) Int Rev Neurobiol , vol.82 , pp. 277-296
    • Van Eldik, L.J.1    Thompson, W.L.2    Ralay, R.H.3    Behanna, H.A.4    Martin, W.D.5
  • 72
    • 33847662852 scopus 로고    scopus 로고
    • Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
    • PMID:17245412
    • Haass C, Selkoe DJ. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 2007; 8:101- 12; PMID:17245412; http://dx.doi.org/10.1038/nrm2101.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 101-112
    • Haass, C.1    Selkoe, D.J.2
  • 73
    • 70350455062 scopus 로고    scopus 로고
    • The betasecretase enzyme BACE in health and Alzheimer's disease: Regulation, cell biology, function, and therapeutic potential
    • PMID:19828790
    • Vassar R, Kovacs DM, Yan R, Wong PC. The betasecretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential. J Neurosci 2009; 29:12787- 94; PMID:19828790; http://dx.doi.org/10.1523/JNEUROSCI.3657-09.2009.
    • (2009) J Neurosci , vol.29 , pp. 12787-12794
    • Vassar, R.1    Kovacs, D.M.2    Yan, R.3    Wong, P.C.4
  • 74
    • 10544248594 scopus 로고    scopus 로고
    • Beta-secretase processing of the betaamyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes
    • PMID:8940150
    • Zhao J, Paganini L, Mucke L, Gordon M, Refolo L, Carman M, et al. Beta-secretase processing of the betaamyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes. J Biol Chem 1996; 271:31407-11; PMID:8940150; http://dx.doi.org/10.1074/jbc.271.49.31407.
    • (1996) J Biol Chem , vol.271 , pp. 31407-31411
    • Zhao, J.1    Paganini, L.2    Mucke, L.3    Gordon, M.4    Refolo, L.5    Carman, M.6
  • 75
    • 30444440132 scopus 로고    scopus 로고
    • BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions
    • PMID:16354928
    • Laird FM, Cai H, Savonenko AV, Farah MH, He K, Melnikova T, et al. BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions. J Neurosci 2005; 25:11693- 709; PMID:16354928; http://dx.doi.org/10.1523/ JNEUROSCI.2766-05.2005.
    • (2005) J Neurosci , vol.25 , pp. 11693-11709
    • Laird, F.M.1    Cai, H.2    Savonenko, A.V.3    Farah, M.H.4    He, K.5    Melnikova, T.6
  • 76
    • 78651435278 scopus 로고    scopus 로고
    • Β-Secretase activity in rat astrocytes: Translational block of BACE1 and modulation of BACE2 expression
    • PMID:21073551
    • Bettegazzi B, Mihailovich M, Di Cesare A, Consonni A, Macco R, Pelizzoni I, et al. β-Secretase activity in rat astrocytes: translational block of BACE1 and modulation of BACE2 expression. Eur J Neurosci 2011; 33:236-43; PMID:21073551; http://dx.doi.org/10.1111/j.1460-9568.2010.07482.x.
    • (2011) Eur J Neurosci , vol.33 , pp. 236-243
    • Bettegazzi, B.1    Mihailovich, M.2    Di Cesare, A.3    Consonni, A.4    MacCo, R.5    Pelizzoni, I.6
  • 77
    • 0029813177 scopus 로고    scopus 로고
    • Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease
    • PMID:8795633
    • Masliah E, Sisk A, Mallory M, Mucke L, Schenk D, Games D. Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease. J Neurosci 1996; 16:5795-811; PMID:8795633.
    • (1996) J Neurosci , vol.16 , pp. 5795-5811
    • Masliah, E.1    Sisk, A.2    Mallory, M.3    Mucke, L.4    Schenk, D.5    Games, D.6
  • 78
    • 0037440474 scopus 로고    scopus 로고
    • Astrocytic expression of the alzheimer's disease beta-secretase (BACE1) is stimulusdependent
    • PMID:12509807
    • Hartlage-Rübsamen M, Zeitschel U, Apelt J, Gärtner U, Franke H, Stahl T, et al. Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulusdependent. Glia 2003; 41:169-79; PMID:12509807; http://dx.doi.org/10.1002/glia.10178.
    • (2003) Glia , vol.41 , pp. 169-179
    • Hartlage-Rübsamen, M.1    Zeitschel, U.2    Apelt, J.3    Gärtner, U.4    Franke, H.5    Stahl, T.6
  • 79
    • 17144427706 scopus 로고    scopus 로고
    • Neuronal and nonneuronal quantitative BACE immunocytochemical expression in the entorhinohippocampal and frontal regions in Alzheimer's disease
    • PMID:15677864
    • Leuba G, Wernli G, Vernay A, Kraftsik R, Mohajeri MH, Saini KD. Neuronal and nonneuronal quantitative BACE immunocytochemical expression in the entorhinohippocampal and frontal regions in Alzheimer's disease. Dement Geriatr Cogn Disord 2005; 19:171-83; PMID:15677864; http://dx.doi.org/10.1159/000083496.
    • (2005) Dement Geriatr Cogn Disord , vol.19 , pp. 171-183
    • Leuba, G.1    Wernli, G.2    Vernay, A.3    Kraftsik, R.4    Mohajeri, M.H.5    Saini, K.D.6
  • 80
    • 13244264935 scopus 로고    scopus 로고
    • Alzheimer's disease beta-secretase BACE1 is not a neuron- specific enzyme
    • PMID:15663471
    • Rossner S, Lange-Dohna C, Zeitschel U, Perez-Polo JR. Alzheimer's disease beta-secretase BACE1 is not a neuron- specific enzyme. J Neurochem 2005; 92:226-34; PMID:15663471; http://dx.doi.org/10.1111/j.1471-4159.2004.02857.x.
    • (2005) J Neurochem , vol.92 , pp. 226-234
    • Rossner, S.1    Lange-Dohna, C.2    Zeitschel, U.3    Perez-Polo, J.R.4
  • 81
    • 84869094484 scopus 로고    scopus 로고
    • Aβ leads to Ca(2+) signaling alterations and transcriptional changes in glial cells
    • PMID:22673114
    • Grolla AA, Fakhfouri G, Balzaretti G, Marcello E, Gardoni F, Canonico PL, et al. Aβ leads to Ca(2+) signaling alterations and transcriptional changes in glial cells. Neurobiol Aging 2012; In Press; PMID:22673114; http://dx.doi.org/10.1016/j.neurobiolaging.2012.05.005.
    • (2012) Neurobiol Aging
    • Grolla, A.A.1    Fakhfouri, G.2    Balzaretti, G.3    Marcello, E.4    Gardoni, F.5    Canonico, P.L.6
  • 82
    • 34248178463 scopus 로고    scopus 로고
    • Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to betaamyloid peptides
    • PMID:17385716
    • Bourne KZ, Ferrari DC, Lange-Dohna C, Rossner S, Wood TG, Perez-Polo JR. Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to betaamyloid peptides. J Neurosci Res 2007; 85:1194- 204; PMID:17385716; http://dx.doi.org/10.1002/jnr.21252.
    • (2007) J Neurosci Res , vol.85 , pp. 1194-1204
    • Bourne, K.Z.1    Ferrari, D.C.2    Lange-Dohna, C.3    Rossner, S.4    Wood, T.G.5    Perez-Polo, J.R.6
  • 83
    • 84865564279 scopus 로고    scopus 로고
    • Aβ-induced Ca(2+) influx regulates astrocytic BACE1 expression via calcineurin/NFAT4 signals
    • PMID:22846573
    • Jin SM, Cho HJ, Kim YW, Hwang JY, Mook-Jung I. Aβ-induced Ca(2+) influx regulates astrocytic BACE1 expression via calcineurin/NFAT4 signals. Biochem Biophys Res Commun 2012; 425:649- 55; PMID:22846573; http://dx.doi.org/10.1016/j.bbrc.2012.07.123.
    • (2012) Biochem Biophys Res Commun , vol.425 , pp. 649-655
    • Jin, S.M.1    Cho, H.J.2    Kim, Y.W.3    Hwang, J.Y.4    Mook-Jung, I.5
  • 84
    • 80055112704 scopus 로고    scopus 로고
    • The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis
    • PMID:22047170
    • Zhao J, O'Connor T, Vassar R. The contribution of activated astrocytes to Aβ production: implications for Alzheimer's disease pathogenesis. J Neuroinflammation 2011; 8:150; PMID:22047170; http://dx.doi.org/10.1186/1742- 2094-8-150.
    • (2011) J Neuroinflammation , vol.8 , pp. 150
    • Zhao, J.1    O'Connor, T.2    Vassar, R.3
  • 85
    • 0030464914 scopus 로고    scopus 로고
    • Betaamyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease
    • PMID:9363804
    • Cummings BJ, Pike CJ, Shankle R, Cotman CW. Betaamyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease. Neurobiol Aging 1996; 17:921-33; PMID:9363804; http://dx.doi.org/10. 1016/S0197-4580(96)00170-4.
    • (1996) Neurobiol Aging , vol.17 , pp. 921-933
    • Cummings, B.J.1    Pike, C.J.2    Shankle, R.3    Cotman, C.W.4
  • 86
    • 0038117796 scopus 로고    scopus 로고
    • Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
    • PMID:10735393
    • Näslund J, Haroutunian V, Mohs R, Davis KL, Davies P, Greengard P, et al. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA 2000; 283:1571-7; PMID:10735393; http://dx.doi.org/10.1001/jama.283.12.1571.
    • (2000) JAMA , vol.283 , pp. 1571-1577
    • Näslund, J.1    Haroutunian, V.2    Mohs, R.3    Davis, K.L.4    Davies, P.5    Greengard, P.6
  • 87
    • 0037067074 scopus 로고    scopus 로고
    • Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer's disease
    • PMID:12044473
    • Bussière T, Friend PD, Sadeghi N, Wicinski B, Lin GI, Bouras C, et al. Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer's disease. Neuroscience 2002; 112:75-91; PMID:12044473; http://dx.doi.org/10.1016/ S0306-4522(02)00056-8.
    • (2002) Neuroscience , vol.112 , pp. 75-91
    • Bussière, T.1    Friend, P.D.2    Sadeghi, N.3    Wicinski, B.4    Lin, G.I.5    Bouras, C.6
  • 88
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • PMID:12399581
    • Selkoe DJ. Alzheimer's disease is a synaptic failure. Science 2002; 298:789-91; PMID:12399581; http://dx.doi.org/10.1126/science.1074069.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 89
    • 33947493213 scopus 로고    scopus 로고
    • Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: Minding the store
    • PMID:17465978
    • Thibault O, Gant JC, Landfield PW. Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging Cell 2007; 6:307-17; PMID:17465978; http://dx.doi.org/10.1111/j.1474-9726.2007.00295.x.
    • (2007) Aging Cell , vol.6 , pp. 307-317
    • Thibault, O.1    Gant, J.C.2    Landfield, P.W.3
  • 90
    • 47749095383 scopus 로고    scopus 로고
    • Linking calcium to Abeta and Alzheimer's disease
    • PMID:18667147
    • Green KN, LaFerla FM. Linking calcium to Abeta and Alzheimer's disease. Neuron 2008; 59:190-4; PMID:18667147; http://dx.doi.org/10.1016/j.neuron.2008. 07.013.
    • (2008) Neuron , vol.59 , pp. 190-194
    • Green, K.N.1    Laferla, F.M.2
  • 91
    • 77549084517 scopus 로고    scopus 로고
    • The dysregulation of intracellular calcium in Alzheimer disease
    • PMID:20080301
    • Supnet C, Bezprozvanny I. The dysregulation of intracellular calcium in Alzheimer disease. Cell Calcium 2010; 47:183-9; PMID:20080301; http://dx.doi.org/10.1016/j.ceca.2009.12.014.
    • (2010) Cell Calcium , vol.47 , pp. 183-189
    • Supnet, C.1    Bezprozvanny, I.2
  • 92
    • 77949899089 scopus 로고    scopus 로고
    • Calcium hypothesis of Alzheimer's disease
    • PMID:19795132
    • Berridge MJ. Calcium hypothesis of Alzheimer's disease. Pflugers Arch 2010; 459:441-9; PMID:19795132; http://dx.doi.org/10.1007/s00424-009-0736-1.
    • (2010) Pflugers Arch , vol.459 , pp. 441-449
    • Berridge, M.J.1
  • 93
    • 38849132181 scopus 로고    scopus 로고
    • Role of calcium in the pathogenesis of Alzheimer's disease and transgenic models
    • PMID:18193650
    • Green KN, Smith IF, Laferla FM. Role of calcium in the pathogenesis of Alzheimer's disease and transgenic models. Subcell Biochem 2007; 45:507-21; PMID:18193650; http://dx.doi.org/10.1007/978-1-4020-6191-2-19.
    • (2007) Subcell Biochem , vol.45 , pp. 507-521
    • Green, K.N.1    Smith, I.F.2    Laferla, F.M.3
  • 94
    • 61349096009 scopus 로고    scopus 로고
    • Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice
    • PMID:19251629
    • Kuchibhotla KV, Lattarulo CR, Hyman BT, Bacskai BJ. Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice. Science 2009; 323:1211-5; PMID:19251629; http://dx.doi.org/10.1126/science. 1169096.
    • (2009) Science , vol.323 , pp. 1211-1215
    • Kuchibhotla, K.V.1    Lattarulo, C.R.2    Hyman, B.T.3    Bacskai, B.J.4
  • 95
    • 0038452658 scopus 로고    scopus 로고
    • Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity
    • PMID:12832532
    • Abramov AY, Canevari L, Duchen MR. Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity. J Neurosci 2003; 23:5088-95; PMID:12832532.
    • (2003) J Neurosci , vol.23 , pp. 5088-5095
    • Abramov, A.Y.1    Canevari, L.2    Duchen, M.R.3
  • 96
    • 1642499152 scopus 로고    scopus 로고
    • Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase
    • PMID:14724257
    • Abramov AY, Canevari L, Duchen MR. Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J Neurosci 2004; 24:565-75; PMID:14724257; http://dx.doi.org/10.1523/JNEUROSCI.4042-03.2004.
    • (2004) J Neurosci , vol.24 , pp. 565-575
    • Abramov, A.Y.1    Canevari, L.2    Duchen, M.R.3
  • 97
    • 29644434681 scopus 로고    scopus 로고
    • Defective tumor necrosis factoralpha- dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease
    • PMID:16253995
    • Rossi D, Brambilla L, Valori CF, Crugnola A, Giaccone G, Capobianco R, et al. Defective tumor necrosis factoralpha- dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease. J Biol Chem 2005; 280:42088-96; PMID:16253995; http://dx.doi.org/10.1074/jbc.M504124200.
    • (2005) J Biol Chem , vol.280 , pp. 42088-42096
    • Rossi, D.1    Brambilla, L.2    Valori, C.F.3    Crugnola, A.4    Giaccone, G.5    Capobianco, R.6
  • 99
    • 33646199097 scopus 로고    scopus 로고
    • Synaptic scaling mediated by glial TNF-alpha
    • PMID:16547515
    • Stellwagen D, Malenka RC. Synaptic scaling mediated by glial TNF-alpha. Nature 2006; 440:1054- 9; PMID:16547515; http://dx.doi.org/10.1038/nature04671.
    • (2006) Nature , vol.440 , pp. 1054-1059
    • Stellwagen, D.1    Malenka, R.C.2
  • 100
    • 44649093265 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha mediates one component of competitive, experience-dependent plasticity in developing visual cortex
    • PMID:18549780
    • Kaneko M, Stellwagen D, Malenka RC, Stryker MP. Tumor necrosis factor-alpha mediates one component of competitive, experience-dependent plasticity in developing visual cortex. Neuron 2008; 58:673-80; PMID:18549780; http://dx.doi.org/10.1016/j.neuron.2008.04.023.
    • (2008) Neuron , vol.58 , pp. 673-680
    • Kaneko, M.1    Stellwagen, D.2    Malenka, R.C.3    Stryker, M.P.4
  • 101
    • 0022005315 scopus 로고
    • A cellular gene encodes scrapie PrP 27-30 protein
    • PMID:2859120
    • Oesch B, Westaway D, Wälchli M, McKinley MP, Kent SB, Aebersold R, et al. A cellular gene encodes scrapie PrP 27-30 protein. Cell 1985; 40:735-46; PMID:2859120; http://dx.doi.org/10.1016/0092-8674(85)90333-2.
    • (1985) Cell , vol.40 , pp. 735-746
    • Oesch, B.1    Westaway, D.2    Wälchli, M.3    McKinley, M.P.4    Kent, S.B.5    Aebersold, R.6
  • 102
    • 0026326210 scopus 로고
    • Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells
    • PMID:1684401
    • McKinley MP, Taraboulos A, Kenaga L, Serban D, Stieber A, DeArmond SJ, et al. Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells. Lab Invest 1991; 65:622-30; PMID:1684401.
    • (1991) Lab Invest , vol.65 , pp. 622-630
    • Mckinley, M.P.1    Taraboulos, A.2    Kenaga, L.3    Serban, D.4    Stieber, A.5    Dearmond, S.J.6
  • 103
    • 0032506187 scopus 로고    scopus 로고
    • Prions
    • PMID:9811807
    • Prusiner SB. Prions. Proc Natl Acad Sci U S A 1998; 95:13363-83; PMID:9811807; http://dx.doi.org/10.1073/pnas.95.23.13363.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13363-13383
    • Prusiner, S.B.1
  • 104
    • 0026600865 scopus 로고
    • Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
    • PMID:1373228
    • Büeler H, Fischer M, Lang Y, Bluethmann H, Lipp HP, DeArmond SJ, et al. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 1992; 356:577-82; PMID:1373228; http://dx.doi.org/10.1038/ 356577a0.
    • (1992) Nature , vol.356 , pp. 577-582
    • Büeler, H.1    Fischer, M.2    Lang, Y.3    Bluethmann, H.4    Lipp, H.P.5    Dearmond, S.J.6
  • 105
    • 0242363656 scopus 로고    scopus 로고
    • Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
    • PMID:14593181
    • Mallucci G, Dickinson A, Linehan J, Klöhn PC, Brandner S, Collinge J. Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science 2003; 302:871-4; PMID:14593181; http://dx.doi.org/10.1126/ science.1090187.
    • (2003) Science , vol.302 , pp. 871-874
    • Mallucci, G.1    Dickinson, A.2    Linehan, J.3    Klöhn, P.C.4    Brandner, S.5    Collinge, J.6
  • 106
    • 0028420937 scopus 로고
    • 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal
    • PMID:7999308
    • Manson JC, Clarke AR, Hooper ML, Aitchison L, McConnell I, Hope J. 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol Neurobiol 1994; 8:121-7; PMID:7999308; http://dx.doi.org/10.1007/BF02780662.
    • (1994) Mol Neurobiol , vol.8 , pp. 121-127
    • Manson, J.C.1    Clarke, A.R.2    Hooper, M.L.3    Aitchison, L.4    McConnell, I.5    Hope, J.6
  • 107
    • 0027372884 scopus 로고
    • Scrapie prions alter receptor-mediated calcium responses in cultured cells
    • PMID:8232952
    • Kristensson K, Feuerstein B, Taraboulos A, Hyun WC, Prusiner SB, DeArmond SJ. Scrapie prions alter receptor-mediated calcium responses in cultured cells. Neurology 1993; 43:2335-41; PMID:8232952; http://dx.doi.org/10.1212/WNL.43.11. 2335.
    • (1993) Neurology , vol.43 , pp. 2335-2341
    • Kristensson, K.1    Feuerstein, B.2    Taraboulos, A.3    Hyun, W.C.4    Prusiner, S.B.5    Dearmond, S.J.6
  • 108
    • 0029794668 scopus 로고    scopus 로고
    • Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release
    • PMID:8797473
    • Wong K, Qiu Y, Hyun W, Nixon R, VanCleff J, Sanchez-Salazar J, et al. Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release. Neurology 1996; 47:741-50; PMID:8797473; http://dx.doi.org/10.1212/WNL.47.3.741.
    • (1996) Neurology , vol.47 , pp. 741-750
    • Wong, K.1    Qiu, Y.2    Hyun, W.3    Nixon, R.4    Vancleff, J.5    Sanchez-Salazar, J.6
  • 109
    • 78650843400 scopus 로고    scopus 로고
    • Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress
    • PMID:21209925
    • Torres M, Castillo K, Armisén R, Stutzin A, Soto C, Hetz C. Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress. PLoS One 2010; 5:e15658; PMID:21209925; http://dx.doi.org/10.1371/journal.pone.0015658.
    • (2010) PLoS One , vol.5
    • Torres, M.1    Castillo, K.2    Armisén, R.3    Stutzin, A.4    Soto, C.5    Hetz, C.6
  • 110
    • 79851481136 scopus 로고    scopus 로고
    • Cellular prion protein is implicated in the regulation of local Ca2+ movements in cerebellar granule neurons
    • PMID:21214552
    • Lazzari C, Peggion C, Stella R, Massimino ML, Lim D, Bertoli A, et al. Cellular prion protein is implicated in the regulation of local Ca2+ movements in cerebellar granule neurons. J Neurochem 2011; 116:881-90; PMID:21214552; http://dx.doi.org/10.1111/j.1471-4159.2010.07015.x.
    • (2011) J Neurochem , vol.116 , pp. 881-890
    • Lazzari, C.1    Peggion, C.2    Stella, R.3    Massimino, M.L.4    Lim, D.5    Bertoli, A.6
  • 111
    • 0025967257 scopus 로고
    • Scrapie-associated prion protein accumulates in astrocytes during scrapie infection
    • PMID:1671170
    • Diedrich JF, Bendheim PE, Kim YS, Carp RI, Haase AT. Scrapie-associated prion protein accumulates in astrocytes during scrapie infection. Proc Natl Acad Sci U S A 1991; 88:375-9; PMID:1671170; http://dx.doi.org/10.1073/pnas.88.2. 375.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 375-379
    • Diedrich, J.F.1    Bendheim, P.E.2    Kim, Y.S.3    Carp, R.I.4    Haase, A.T.5
  • 112
    • 0023235753 scopus 로고
    • Changes in the localization of brain prion proteins during scrapie infection
    • PMID:3112607
    • DeArmond SJ, Mobley WC, DeMott DL, Barry RA, Beckstead JH, Prusiner SB. Changes in the localization of brain prion proteins during scrapie infection. Neurology 1987; 37:1271-80; PMID:3112607; http://dx.doi.org/10.1212/WNL.37.8. 1271.
    • (1987) Neurology , vol.37 , pp. 1271-1280
    • DeArmond, S.J.1    Mobley, W.C.2    DeMott, D.L.3    Barry, R.A.4    Beckstead, J.H.5    Prusiner, S.B.6
  • 113
    • 0027209988 scopus 로고
    • Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform
    • PMID:8101989
    • DeArmond SJ, Yang SL, Lee A, Bowler R, Taraboulos A, Groth D, et al. Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform. Proc Natl Acad Sci U S A 1993; 90:6449-53; PMID:8101989; http://dx.doi.org/10.1073/pnas.90.14.6449.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6449-6453
    • DeArmond, S.J.1    Yang, S.L.2    Lee, A.3    Bowler, R.4    Taraboulos, A.5    Groth, D.6
  • 114
    • 0031803512 scopus 로고    scopus 로고
    • Role of microglia in neuronal cell death in prion disease
    • PMID:9669696
    • Giese A, Brown DR, Groschup MH, Feldmann C, Haist I, Kretzschmar HA. Role of microglia in neuronal cell death in prion disease. Brain Pathol 1998; 8:449-57; PMID:9669696; http://dx.doi.org/10.1111/j.1750-3639.1998.tb00167.x.
    • (1998) Brain Pathol , vol.8 , pp. 449-457
    • Giese, A.1    Brown, D.R.2    Groschup, M.H.3    Feldmann, C.4    Haist, I.5    Kretzschmar, H.A.6
  • 115
    • 0028203591 scopus 로고
    • Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie
    • PMID:8139024
    • Campbell IL, Eddleston M, Kemper P, Oldstone MB, Hobbs MV. Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie. J Virol 1994; 68:2383-7; PMID:8139024.
    • (1994) J Virol , vol.68 , pp. 2383-2387
    • Campbell, I.L.1    Eddleston, M.2    Kemper, P.3    Oldstone, M.B.4    Hobbs, M.V.5
  • 116
    • 0032721724 scopus 로고    scopus 로고
    • Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapieinfected mice
    • PMID:10581394
    • Kim JI, Ju WK, Choi JH, Choi E, Carp RI, Wisniewski HM, et al. Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapieinfected mice. Brain Res Mol Brain Res 1999; 73:17- 27; PMID:10581394; http://dx.doi.org/10.1016/S0169-328X(99)00229-6.
    • (1999) Brain Res Mol Brain Res , vol.73 , pp. 17-27
    • Kim, J.I.1    Ju, W.K.2    Choi, J.H.3    Choi, E.4    Carp, R.I.5    Wisniewski, H.M.6
  • 117
    • 70350325620 scopus 로고    scopus 로고
    • Analysis of protein levels of 24 cytokines in scrapie agent-infected brain and glial cell cultures from mice differing in prion protein expression levels
    • PMID:19710140
    • Tribouillard-Tanvier D, Striebel JF, Peterson KE, Chesebro B. Analysis of protein levels of 24 cytokines in scrapie agent-infected brain and glial cell cultures from mice differing in prion protein expression levels. J Virol 2009; 83:11244-53; PMID:19710140; http://dx.doi.org/10.1128/JVI.01413-09.
    • (2009) J Virol , vol.83 , pp. 11244-11253
    • Tribouillard-Tanvier, D.1    Striebel, J.F.2    Peterson, K.E.3    Chesebro, B.4
  • 118
    • 61349156118 scopus 로고    scopus 로고
    • Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
    • PMID:19251627
    • Kwiatkowski TJ Jr., Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 2009; 323:1205- 8; PMID:19251627; http://dx.doi.org/10.1126/science.1166066.
    • (2009) Science , vol.323 , pp. 1205-1208
    • Kwiatkowski, Jr.T.J.1    Bosco, D.A.2    Leclerc, A.L.3    Tamrazian, E.4    Vanderburg, C.R.5    Russ, C.6
  • 119
    • 61349162349 scopus 로고    scopus 로고
    • Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
    • PMID:19251628
    • Vance C, Rogelj B, Hortobágyi T, De Vos KJ, Nishimura AL, Sreedharan J, et al. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science 2009; 323:1208-11; PMID:19251628; http://dx.doi.org/10.1126/science.1165942.
    • (2009) Science , vol.323 , pp. 1208-1211
    • Vance, C.1    Rogelj, B.2    Hortobágyi, T.3    De Vos, K.J.4    Nishimura, A.L.5    Sreedharan, J.6
  • 120
    • 62749193868 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis
    • PMID:19192301
    • Wijesekera LC, Leigh PN. Amyotrophic lateral sclerosis. Orphanet J Rare Dis 2009; 4:3; PMID:19192301; http://dx.doi.org/10.1186/1750-1172-4-3.
    • (2009) Orphanet J Rare Dis , vol.4 , pp. 3
    • Wijesekera, L.C.1    Leigh, P.N.2
  • 121
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • PMID:8446170
    • Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993; 362:59-62; PMID:8446170; http://dx.doi.org/10.1038/362059a0.
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3    Figlewicz, D.A.4    Sapp, P.5    Hentati, A.6
  • 122
    • 0028284779 scopus 로고
    • Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
    • PMID:8209258
    • Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD, et al. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 1994; 264:1772-5; PMID:8209258; http://dx.doi.org/ 10.1126/science.8209258.
    • (1994) Science , vol.264 , pp. 1772-1775
    • Gurney, M.E.1    Pu, H.2    Chiu, A.Y.3    Dal Canto, M.C.4    Polchow, C.Y.5    Alexander, D.D.6
  • 123
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • PMID:7605627
    • Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, et al. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 1995; 14:1105-16; PMID:7605627; http://dx.doi.org/10.1016/0896-6273(95)90259-7.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6
  • 124
    • 0031051485 scopus 로고    scopus 로고
    • ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
    • PMID:9052802
    • Bruijn LI, Becher MW, Lee MK, Anderson KL, Jenkins NA, Copeland NG, et al. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron 1997; 18:327-38; PMID:9052802; http://dx.doi.org/10.1016/S0896-6273(00)80272-X.
    • (1997) Neuron , vol.18 , pp. 327-338
    • Bruijn, L.I.1    Becher, M.W.2    Lee, M.K.3    Anderson, K.L.4    Jenkins, N.A.5    Copeland, N.G.6
  • 125
    • 34247475338 scopus 로고    scopus 로고
    • Astrocytes expressing ALSlinked mutated SOD1 release factors selectively toxic to motor neurons
    • PMID:17435755
    • Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, et al. Astrocytes expressing ALSlinked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci 2007; 10:615-22; PMID:17435755; http://dx.doi.org/10.1038/nn1876.
    • (2007) Nat Neurosci , vol.10 , pp. 615-622
    • Nagai, M.1    Re, D.B.2    Nagata, T.3    Chalazonitis, A.4    Jessell, T.M.5    Wichterle, H.6
  • 126
    • 0037022339 scopus 로고    scopus 로고
    • Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutantmediated amyotrophic lateral sclerosis (ALS)
    • PMID:11818550
    • Howland DS, Liu J, She Y, Goad B, Maragakis NJ, Kim B, et al. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutantmediated amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci U S A 2002; 99:1604-9; PMID:11818550; http://dx.doi.org/10.1073/pnas.032539299.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 1604-1609
    • Howland, D.S.1    Liu, J.2    She, Y.3    Goad, B.4    Maragakis, N.J.5    Kim, B.6
  • 127
    • 42249102078 scopus 로고    scopus 로고
    • Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
    • PMID:18282652, 2008.01.001
    • Turner BJ, Talbot K. Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. Prog Neurobiol 2008; 85:94-134; PMID:18282652; http://dx.doi.org/10.1016/j.pneurobio 2008.01.001.
    • (2008) Prog Neurobiol , vol.85 , pp. 94-134
    • Turner, B.J.1    Talbot, K.2
  • 128
    • 0141642203 scopus 로고    scopus 로고
    • Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
    • PMID:14526083
    • Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, et al. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science 2003; 302:113-7; PMID:14526083; http://dx.doi.org/10.1126/ science.1086071.
    • (2003) Science , vol.302 , pp. 113-117
    • Clement, A.M.1    Nguyen, M.D.2    Roberts, E.A.3    Garcia, M.L.4    Boillée, S.5    Rule, M.6
  • 129
    • 0036787810 scopus 로고    scopus 로고
    • Inflammatory processes in amyotrophic lateral sclerosis
    • PMID:12362410
    • McGeer PL, McGeer EG. Inflammatory processes in amyotrophic lateral sclerosis. Muscle Nerve 2002; 26:459-70; PMID:12362410; http://dx.doi.org/10. 1002/mus.10191.
    • (2002) Muscle Nerve , vol.26 , pp. 459-470
    • McGeer, P.L.1    McGeer, E.G.2
  • 130
    • 33744798774 scopus 로고    scopus 로고
    • Onset and progression in inherited ALS determined by motor neurons and microglia
    • PMID:16741123
    • Boillée S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, et al. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 2006; 312:1389-92; PMID:16741123; http://dx.doi.org/10.1126/science.1123511.
    • (2006) Science , vol.312 , pp. 1389-1392
    • Boillée, S.1    Yamanaka, K.2    Lobsiger, C.S.3    Copeland, N.G.4    Jenkins, N.A.5    Kassiotis, G.6
  • 131
    • 39749188753 scopus 로고    scopus 로고
    • Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
    • PMID:18246065
    • Yamanaka K, Chun SJ, Boillee S, Fujimori-Tonou N, Yamashita H, Gutmann DH, et al. Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat Neurosci 2008; 11:251-3; PMID:18246065; http://dx.doi.org/10.1038/nn2047.
    • (2008) Nat Neurosci , vol.11 , pp. 251-253
    • Yamanaka, K.1    Chun, S.J.2    Boillee, S.3    Fujimori-Tonou, N.4    Yamashita, H.5    Gutmann, D.H.6
  • 132
    • 33750478657 scopus 로고    scopus 로고
    • Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis
    • PMID:17043238
    • Beers DR, Henkel JS, Xiao Q, Zhao W, Wang J, Yen AA, et al. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 2006; 103:16021- 6; PMID:17043238; http://dx.doi.org/10.1073/pnas.0607423103.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 16021-16026
    • Beers, D.R.1    Henkel, J.S.2    Xiao, Q.3    Zhao, W.4    Wang, J.5    Yen, A.A.6
  • 133
    • 78650550891 scopus 로고    scopus 로고
    • Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice
    • PMID:20962037
    • Wang L, Gutmann DH, Roos RP. Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice. Hum Mol Genet 2011; 20:286-93; PMID:20962037; http://dx.doi.org/10.1093/hmg/ddq463.
    • (2011) Hum Mol Genet , vol.20 , pp. 286-293
    • Wang, L.1    Gutmann, D.H.2    Roos, R.P.3
  • 134
    • 80055074312 scopus 로고    scopus 로고
    • Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo
    • PMID:21969586
    • Papadeas ST, Kraig SE, O'Banion C, Lepore AC, Maragakis NJ. Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo. Proc Natl Acad Sci U S A 2011; 108:17803-8; PMID:21969586; http://dx.doi.org/10.1073/pnas.1103141108.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 17803-17808
    • Papadeas, S.T.1    Kraig, S.E.2    O'Banion, C.3    Lepore, A.C.4    Maragakis, N.J.5
  • 135
    • 33746548027 scopus 로고    scopus 로고
    • Expression of ubiquitin and proteasome in motorneurons and astrocytes of spinal cords from patients with amyotrophic lateral sclerosis
    • PMID:16806703, 2006.06.009
    • Mendonça DM, Chimelli L, Martinez AM. Expression of ubiquitin and proteasome in motorneurons and astrocytes of spinal cords from patients with amyotrophic lateral sclerosis. Neurosci Lett 2006; 404:315- 9; PMID:16806703; http://dx.doi.org/10.1016/j.neulet. 2006.06.009.
    • (2006) Neurosci Lett , vol.404 , pp. 315-319
    • Mendonça, D.M.1    Chimelli, L.2    Martinez, A.M.3
  • 136
    • 0034610328 scopus 로고    scopus 로고
    • Caspase-1 and -3 are sequentially activated in motor neuron death in Cu, Zn superoxide dismutase- mediated familial amyotrophic lateral sclerosis
    • PMID:11095709
    • Pasinelli P, Houseweart MK, Brown RH Jr., Cleveland DW. Caspase-1 and -3 are sequentially activated in motor neuron death in Cu, Zn superoxide dismutase- mediated familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 2000; 97:13901- 6; PMID:11095709; http://dx.doi.org/10.1073/pnas.240305897.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13901-13906
    • Pasinelli, P.1    Houseweart, M.K.2    Brown, Jr.R.H.3    Cleveland, D.W.4
  • 137
    • 33344462702 scopus 로고    scopus 로고
    • Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF
    • PMID:16474388
    • Pun S, Santos AF, Saxena S, Xu L, Caroni P. Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF. Nat Neurosci 2006; 9:408-19; PMID:16474388; http://dx.doi.org/10.1038/nn1653.
    • (2006) Nat Neurosci , vol.9 , pp. 408-419
    • Pun, S.1    Santos, A.F.2    Saxena, S.3    Xu, L.4    Caroni, P.5
  • 139
    • 33645711020 scopus 로고    scopus 로고
    • The role of metabotropic glutamate receptors for the generation of calcium oscillations in rat hippocampal astrocytes in situ
    • PMID:16079243
    • Zur Nieden R, Deitmer JW. The role of metabotropic glutamate receptors for the generation of calcium oscillations in rat hippocampal astrocytes in situ. Cereb Cortex 2006; 16:676-87; PMID:16079243; http://dx.doi.org/10.1093/ cercor/bhj013.
    • (2006) Cereb Cortex , vol.16 , pp. 676-687
    • Zur, N.R.1    Deitmer, J.W.2
  • 140
    • 42949166848 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: Prevention by mitochondrial- targeted antioxidants
    • PMID:18417691
    • Cassina P, Cassina A, Pehar M, Castellanos R, Gandelman M, de León A, et al. Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial- targeted antioxidants. J Neurosci 2008; 28:4115- 22; PMID:18417691; http://dx.doi.org/10.1523/JNEUROSCI. 5308-07.2008.
    • (2008) J Neurosci , vol.28 , pp. 4115-4122
    • Cassina, P.1    Cassina, A.2    Pehar, M.3    Castellanos, R.4    Gandelman, M.5    De León, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.