Aβ-induced Ca2+ influx regulates astrocytic BACE1 expression via calcineurin/NFAT4 signals

Biochemical and Biophysical Research Communications

Volumn 425, Issue 3, 2012, Pages 649-655

  Jin, Seok Min ^a   Cho, Hyun Jin ^a   Kim, Yong Woo ^a   Hwang, Ji Yeon ^a   Mook Jung, Inhee ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

Secretase; Alzheimer's disease; BACE1; Calcineurin; Calcium; NFAT4

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[25-35]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; CALCINEURIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM ION; CALCIUM IONOPHORE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT4; UNCLASSIFIED DRUG;

AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GLIA CELL; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; ASTROCYTES; CALCINEURIN; CALCIUM; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MICE; MICE, TRANSGENIC; NFATC TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION;

MUS;

EID: 84865564279     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.07.123     Document Type: Article

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