-
1
-
-
11844250564
-
Drug therapy: Insulin analogues
-
Hirsch IB. Drug therapy: insulin analogues. N. Engl. J. Med. 352, 174-183 (2005).
-
(2005)
N. Engl. J. Med
, vol.352
, pp. 174-183
-
-
Hirsch, I.B.1
-
2
-
-
33748752402
-
Is the oral route possible for peptide and protein drug delivery?
-
Morishita M, Peppas NA. Is the oral route possible for peptide and protein drug delivery? Drug Discov. Today 11, 905-910 (2006).
-
(2006)
Drug Discov. Today
, vol.11
, pp. 905-910
-
-
Morishita, M.1
Peppas, N.A.2
-
3
-
-
36248965689
-
Current challenges in non-invasive insulin delivery systems: A comparative review
-
Khafagy El-S, Morishita M, Onuki Y, Takayama K. Current challenges in non-invasive insulin delivery systems: a comparative review. Adv. Drug Deliv. Rev. 59, 1521-1546(2007).
-
(2007)
Adv. Drug Deliv. Rev
, vol.59
, pp. 1521-1546
-
-
El-S, K.1
Morishita, M.2
Onuki, Y.3
Takayama, K.4
-
4
-
-
0037393955
-
Challenges for the oral delivery of macromolecules
-
Goldberg M, Gomez-Orellana I. Challenges for the oral delivery of macromolecules. Nat. Rev. Drug Discov. 2, 289-295 (2003).
-
(2003)
Nat. Rev. Drug Discov
, vol.2
, pp. 289-295
-
-
Goldberg, M.1
Gomez-Orellana, I.2
-
5
-
-
1542498664
-
Alternative routes of insulin delivery
-
Owens DR, Zinman B, Bolli G. Alternative routes of insulin delivery. Diabetic Med. 20, 886-898 (2003).
-
(2003)
Diabetic Med
, vol.20
, pp. 886-898
-
-
Owens, D.R.1
Zinman, B.2
Bolli, G.3
-
6
-
-
0027942425
-
Enhancement of intestinal insulin absorption by bile salt-fatty acid mixed micelles in dogs
-
Scott-Moncrieff JC, Shao Z, Mitra AK. Enhancement of intestinal insulin absorption by bile salt-fatty acid mixed micelles in dogs. J. Pharm. Sci. 83, 1465-1469 (1994).
-
(1994)
J. Pharm. Sci
, vol.83
, pp. 1465-1469
-
-
Scott-Moncrieff, J.C.1
Shao, Z.2
Mitra, A.K.3
-
7
-
-
0027538539
-
2EDTA and sodium glycocholate on intestinal absorption of insulin
-
Morishita M, Morishita I, Takayama K, Machida Y, Nagai T. Site-dependent effect of aprotinin, sodium caprate, Na2EDTA and sodium glycocholate on intestinal absorption of insulin. Biol. Pharm. Bull. 16, 68-72 (1993).
-
(1993)
Biol. Pharm. Bull
, vol.16
, pp. 68-72
-
-
Morishita, M.1
Morishita, I.2
Takayama, K.3
Machida, Y.4
Nagai, T.5
-
8
-
-
0027988721
-
Effects of various protease inhibitors on the intestinal absorption and degradation of insulin in rats
-
Yamamoto A, Taniguchi T, Rikyuu K et al. Effects of various protease inhibitors on the intestinal absorption and degradation of insulin in rats. Pharm. Res. 11, 1496-1500 (1994).
-
(1994)
Pharm. Res
, vol.11
, pp. 1496-1500
-
-
Yamamoto, A.1
Taniguchi, T.2
Rikyuu, K.3
-
9
-
-
0029895328
-
Enteral absorption of insulin in rats from mucoadhesive chitosan-coated liposomes
-
Takeuchi H, Yamamoto H, Niwa T, Hino T, Kawashima Y. Enteral absorption of insulin in rats from mucoadhesive chitosan-coated liposomes. Pharm. Res. 13, 896-901 (1996).
-
(1996)
Pharm. Res
, vol.13
, pp. 896-901
-
-
Takeuchi, H.1
Yamamoto, H.2
Niwa, T.3
Hino, T.4
Kawashima, Y.5
-
10
-
-
31544432290
-
Novel oral insulin delivery systems based on complexation polymer hydrogels: Single and multiple administration studies in type 1 and 2 diabetic rats
-
Morishita M, Goto T, Nakamura K, Lowman AM, Takayama K, Peppas NA. Novel oral insulin delivery systems based on complexation polymer hydrogels: Single and multiple administration studies in type 1 and 2 diabetic rats. J. Control. Release 110, 587-594 (2006).
-
(2006)
J. Control. Release
, vol.110
, pp. 587-594
-
-
Morishita, M.1
Goto, T.2
Nakamura, K.3
Lowman, A.M.4
Takayama, K.5
Peppas, N.A.6
-
11
-
-
0344876583
-
Potential utility of various protease inhibitors for improving the intestinal absorption of insulin in rats
-
Liu H, Tang R, Pan WS, Zhang Y, Liu H. Potential utility of various protease inhibitors for improving the intestinal absorption of insulin in rats. J. Pharm. Pharmacol. 55, 1523-1529 (2003).
-
(2003)
J. Pharm. Pharmacol
, vol.55
, pp. 1523-1529
-
-
Liu, H.1
Tang, R.2
Pan, W.S.3
Zhang, Y.4
Liu, H.5
-
13
-
-
0842303582
-
Gastrointestinal absorption enhancement of insulin by administration of enteric microspheres and SNAC to rats
-
Qi R, Ping QN. Gastrointestinal absorption enhancement of insulin by administration of enteric microspheres and SNAC to rats. J. Microencapsul. 21, 37-45 (2004).
-
(2004)
J. Microencapsul
, vol.21
, pp. 37-45
-
-
Qi, R.1
Ping, Q.N.2
-
14
-
-
5344233384
-
The effect of various liposome formulations on insulin penetration across Caco-2 cell monolayer
-
Degim Z, Unal N, Essiz D, Abbasoglu U. The effect of various liposome formulations on insulin penetration across Caco-2 cell monolayer. Life Sci. 75, 2819-2827 (2004).
-
(2004)
Life Sci
, vol.75
, pp. 2819-2827
-
-
Degim, Z.1
Unal, N.2
Essiz, D.3
Abbasoglu, U.4
-
15
-
-
0029590815
-
Absorption of insulin using water-in-oil-in-water emulsion from an enteral loop in rats
-
Matsuzawa A, Morishita M, Takayama K, Nagai T. Absorption of insulin using water-in-oil-in-water emulsion from an enteral loop in rats. Biol. Pharm. Bull. 18, 1718-1723 (1995).
-
(1995)
Biol. Pharm. Bull
, vol.18
, pp. 1718-1723
-
-
Matsuzawa, A.1
Morishita, M.2
Takayama, K.3
Nagai, T.4
-
16
-
-
0034713409
-
The dose-related hypoglycemic effects of insulin emulsions incorporating highly purified EPA and DHA
-
Morishita M, Kajita M, Suzuki A et al. The dose-related hypoglycemic effects of insulin emulsions incorporating highly purified EPA and DHA. Int. J. Pharm. 201, 175-185 (2000).
-
(2000)
Int. J. Pharm
, vol.201
, pp. 175-185
-
-
Morishita, M.1
Kajita, M.2
Suzuki, A.3
-
17
-
-
0032823008
-
Oral delivery of insulin using pH-responsive complexation gels
-
Lawman A, Morishita M, Kajita M, Nagai T, Peppas N. Oral delivery of insulin using pH-responsive complexation gels. J. Pharm. Sci. 88, 933-937 (1999).
-
(1999)
J. Pharm. Sci
, vol.88
, pp. 933-937
-
-
Lawman, A.1
Morishita, M.2
Kajita, M.3
Nagai, T.4
Peppas, N.5
-
18
-
-
1842857988
-
Mucosal insulin delivery systems based on complexation polymer hydrogels: Effect of particle size on insulin enteral absorption
-
Morishita M, Goto T, Peppas NA et al. Mucosal insulin delivery systems based on complexation polymer hydrogels: effect of particle size on insulin enteral absorption. J. Control. Release 97, 115-124 (2004).
-
(2004)
J. Control. Release
, vol.97
, pp. 115-124
-
-
Morishita, M.1
Goto, T.2
Peppas, N.A.3
-
19
-
-
0028038011
-
Enhanced oral absorption of insulin from desolvated fatty acid-sodium glycocholate emulsions
-
Mesiha M, Plakogiannis F, Vejosoth S. Enhanced oral absorption of insulin from desolvated fatty acid-sodium glycocholate emulsions. Int. J. Pharm. 111, 213-216 (1994).
-
(1994)
Int. J. Pharm
, vol.111
, pp. 213-216
-
-
Mesiha, M.1
Plakogiannis, F.2
Vejosoth, S.3
-
20
-
-
0036156214
-
The effect of oral absorption enhancers on the in vivo performance of insulin-loaded poly(ethylcyanoacrylate) nanospheres in diabetic rats
-
Radwant MA, Aboul-Enein HY. The effect of oral absorption enhancers on the in vivo performance of insulin-loaded poly(ethylcyanoacrylate) nanospheres in diabetic rats. J. Microencapsul. 19, 225-235 (2002).
-
(2002)
J. Microencapsul
, vol.19
, pp. 225-235
-
-
Radwant, M.A.1
Aboul-Enein, H.Y.2
-
21
-
-
0030006079
-
Oral administration of insulin as poly(vinyl alcohol)-gel spheres in diabetic rats
-
Kimura T, Sato K, Sugimoto K et al. Oral administration of insulin as poly(vinyl alcohol)-gel spheres in diabetic rats. Biol. Pharm. Bull. 19, 897-900 (1996).
-
(1996)
Biol. Pharm. Bull
, vol.19
, pp. 897-900
-
-
Kimura, T.1
Sato, K.2
Sugimoto, K.3
-
22
-
-
0031446134
-
Poly(alkyl cyanoacrylate) nanospheres for oral administration of insulin
-
Damge C, Vranckx H, Balschmidt P, Couvreur P. Poly(alkyl cyanoacrylate) nanospheres for oral administration of insulin. J. Pharm. Sci. 86, 1403-1409 (1997).
-
(1997)
J. Pharm. Sci
, vol.86
, pp. 1403-1409
-
-
Damge, C.1
Vranckx, H.2
Balschmidt, P.3
Couvreur, P.4
-
23
-
-
0034468106
-
Design and in vivo evaluation of an oral delivery system for insulin
-
Marschutz MK, Caliceti P, Bernkop-Schnurch A. Design and in vivo evaluation of an oral delivery system for insulin. Pharm. Res. 17, 1468-1474 (2000).
-
(2000)
Pharm. Res
, vol.17
, pp. 1468-1474
-
-
Marschutz, M.K.1
Caliceti, P.2
Bernkop-Schnurch, A.3
-
24
-
-
0037393955
-
Challenges for the oral delivery of macromolecules
-
Goldberg M, Gomez-Orellana I. Challenges for the oral delivery of macromolecules. Nat. Rev. Drug.Discov. 2, 289-295(2003).
-
(2003)
Nat. Rev. Drug.Discov
, vol.2
, pp. 289-295
-
-
Goldberg, M.1
Gomez-Orellana, I.2
-
25
-
-
0028657017
-
Enzymatic barriers for GI peptide and protein delivery
-
Woodley JF. Enzymatic barriers for GI peptide and protein delivery. Crit. Rev. Ther. Drug. Carrier. Syst. 11, 61-95 (1994).
-
(1994)
Crit. Rev. Ther. Drug. Carrier. Syst
, vol.11
, pp. 61-95
-
-
Woodley, J.F.1
-
26
-
-
0029948911
-
Evidence for the existence of insulin-degrading enzyme on the brush-border membranes of rat enterocytes
-
Chang LL, Bai JPF. Evidence for the existence of insulin-degrading enzyme on the brush-border membranes of rat enterocytes. Pharm. Res. 13, 801-803 (1996).
-
(1996)
Pharm. Res
, vol.13
, pp. 801-803
-
-
Chang, L.L.1
Jpf, B.2
-
27
-
-
0031791711
-
Novel approaches for oral delivery of macromolecules
-
Fasano A. Novel approaches for oral delivery of macromolecules. J. Pharm. Sci. 87, 1351-1356 (1998).
-
(1998)
J. Pharm. Sci
, vol.87
, pp. 1351-1356
-
-
Fasano, A.1
-
28
-
-
17844406157
-
Intestinal absorption enhancement via the paracellular route by fatty acids, chitosans and others: A target for drug delivery
-
Cano-Cebrián MJ, Zornoza T, Granero L, Polache A. Intestinal absorption enhancement via the paracellular route by fatty acids, chitosans and others: a target for drug delivery. Curr. Drug. Deliv. 2, 9-22 (2005).
-
(2005)
Curr. Drug. Deliv
, vol.2
, pp. 9-22
-
-
Cano-Cebrián, M.J.1
Zornoza, T.2
Granero, L.3
Polache, A.4
-
29
-
-
38349174536
-
On the biomedical promise of cell penetrating peptides: Limits versus prospects
-
Foerg C, Merkle HP. On the biomedical promise of cell penetrating peptides: limits versus prospects. J. Pharm. Sci. 97, 144-162 (2008).
-
(2008)
J. Pharm. Sci
, vol.97
, pp. 144-162
-
-
Foerg, C.1
Merkle, H.P.2
-
30
-
-
68549110328
-
Twenty years of cell-penetrating peptides: From molecular mechanisms to therapeutics
-
Heitz F, Morris MC, Divita G. Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics. Br. J. Pharmacol. 157, 195-206 (2009).
-
(2009)
Br. J. Pharmacol
, vol.157
, pp. 195-206
-
-
Heitz, F.1
Morris, M.C.2
Divita, G.3
-
31
-
-
70349456654
-
Recent advances in the use of cell-penetrating peptides for medical and biological applications
-
Fonseca SB, Pereira MP, Kelly SO. Recent advances in the use of cell-penetrating peptides for medical and biological applications. Adv. Drug Deliv. Rev. 61, 953-964 (2009).
-
(2009)
Adv. Drug Deliv. Rev
, vol.61
, pp. 953-964
-
-
Fonseca, S.B.1
Pereira, M.P.2
Kelly, S.O.3
-
32
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vives E, Brodin P, Lebleu B. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272, 16010-16017 (1997).
-
(1997)
J. Biol. Chem
, vol.272
, pp. 16010-16017
-
-
Vives, E.1
Brodin, P.2
Lebleu, B.3
-
33
-
-
0033794501
-
Polyarginine enters cells more efficiently than other polycationic homopolymers
-
Mitchell DJ, Kim DT, Steinman L, Fathman CG, Rothbard JB. Polyarginine enters cells more efficiently than other polycationic homopolymers. J. Pept. Res. 56, 318-325 (2000).
-
(2000)
J. Pept. Res
, vol.56
, pp. 318-325
-
-
Mitchell, D.J.1
Kim, D.T.2
Steinman, L.3
Fathman, C.G.4
Rothbard, J.B.5
-
34
-
-
0035937124
-
Arginine-rich peptides: An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery
-
Futaki S, Suzuki T, Ohashi W et al. Arginine-rich peptides: an abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J. Biol. Chem. 276, 5836-5840 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 5836-5840
-
-
Futaki, S.1
Suzuki, T.2
Ohashi, W.3
-
35
-
-
38949188925
-
Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides
-
Nakase I, Takeuchi T, Tanaka G, Futaki S. Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides. Adv. Drug Deliv. Rev. 60, 598-607 (2008).
-
(2008)
Adv. Drug Deliv. Rev
, vol.60
, pp. 598-607
-
-
Nakase, I.1
Takeuchi, T.2
Tanaka, G.3
Futaki, S.4
-
36
-
-
0028239908
-
The third helix of the Antennapedia homeodomaintranslocates through biological membranes
-
Derossi D, Joliot AH, Chassaing G, Prochiantz A. The third helix of the Antennapedia homeodomaintranslocates through biological membranes. J. Biol. Chem. 269, 10444-10450 (1994).
-
(1994)
J. Biol. Chem
, vol.269
, pp. 10444-10450
-
-
Derossi, D.1
Joliot, A.H.2
Chassaing, G.3
Prochiantz, A.4
-
37
-
-
0029982569
-
Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent
-
Derossi D, Calvet S, Trembleau A, Brunissen A, Chassaing G, Prochiantz A. Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J. Biol. Chem. 271, 18188-18193 (1996).
-
(1996)
J. Biol. Chem
, vol.271
, pp. 18188-18193
-
-
Derossi, D.1
Calvet, S.2
Trembleau, A.3
Brunissen, A.4
Chassaing, G.5
Prochiantz, A.6
-
38
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285, 1569-1572 (1999).
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
39
-
-
0036298282
-
Conjugates of antisense oligonucleotides with the TAT and antennapedia cell-penetrating peptides: Effects on cellular uptake, binding to target sequences, and biologic actions
-
Astriab-Fisher A, Sergueev D, Fisher M, Shaw BR, Juliano RL. Conjugates of antisense oligonucleotides with the TAT and antennapedia cell-penetrating peptides: effects on cellular uptake, binding to target sequences, and biologic actions. Pharm. Res. 19, 744-754 (2002).
-
(2002)
Pharm. Res
, vol.19
, pp. 744-754
-
-
Astriab-Fisher, A.1
Sergueev, D.2
Fisher, M.3
Shaw, B.R.4
Juliano, R.L.5
-
41
-
-
3843050301
-
Enhanced heparan sulfate proteoglycan-mediated uptake of cell-penetrating peptide-modified liposomes
-
Marty C, Meylan C, Schott H, Ballmer-Hofer K, Schwendener RA. Enhanced heparan sulfate proteoglycan-mediated uptake of cell-penetrating peptide-modified liposomes. Cell. Mol. Life Sci. 61, 1785-1794 (2004).
-
(2004)
Cell. Mol. Life Sci
, vol.61
, pp. 1785-1794
-
-
Marty, C.1
Meylan, C.2
Schott, H.3
Ballmer-Hofer, K.4
Schwendener, R.A.5
-
42
-
-
13844298046
-
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
-
Gupta B, Levchenko TS, Torchilin VP. Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv. Drug Deliv. Rev. 57, 637-651 (2005).
-
(2005)
Adv. Drug Deliv. Rev
, vol.57
, pp. 637-651
-
-
Gupta, B.1
Levchenko, T.S.2
Torchilin, V.P.3
-
43
-
-
33646236541
-
Oligoarginine vectors for intracellular delivery: Design and cellular-uptake mechanisms
-
Futaki S. Oligoarginine vectors for intracellular delivery: design and cellular-uptake mechanisms. Biopolymers 84, 241-249 (2006).
-
(2006)
Biopolymers
, vol.84
, pp. 241-249
-
-
Futaki, S.1
-
44
-
-
0346460957
-
Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake
-
Richard JP, Melikov K, Vives E et al. Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J. Biol. Chem. 278, 585-590 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
Melikov, K.2
Vives, E.3
-
45
-
-
10344221003
-
Cellular uptake of arginine-rich peptides: Roles for macropinocytosis and actin rearrangement
-
NakaseI, Niwa M, Takeuchi T et al. Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement. Mol. Ther. 10, 1011-1022 (2004).
-
(2004)
Mol. Ther
, vol.10
, pp. 1011-1022
-
-
Nakasei Niwa, M.1
Takeuchi, T.2
-
46
-
-
0041816277
-
Antennapedia and HIV transactivator of transcription (TAT protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans
-
Console S, Marty C, Garcia-Echeverria C, Schwendener R, Ballmer-Hofer K. Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans. J. Biol. Chem. 278, 35109-35114 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 35109-35114
-
-
Console, S.1
Marty, C.2
Garcia-Echeverria, C.3
Schwendener, R.4
Ballmer-Hofer, K.5
-
47
-
-
0141446039
-
Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins
-
Fittipaldi A, Ferrari A, Zoppe M et al. Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins. J. Biol. Chem. 278, 34141-34149 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 34141-34149
-
-
Fittipaldi, A.1
Ferrari, A.2
Zoppe, M.3
-
48
-
-
2342595835
-
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
-
Wadia JS, Stan RV, Dowdy SF. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat. Med. 10, 310-315 (2004).
-
(2004)
Nat. Med
, vol.10
, pp. 310-315
-
-
Wadia, J.S.1
Stan, R.V.2
Dowdy, S.F.3
-
49
-
-
17644386231
-
Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
-
Richard JP, Melikov K, Brooks H, Prevot P, Lebleu B, Chernomordik LV. Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J. Biol. Chem. 280, 15300-15306 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 15300-15306
-
-
Richard, J.P.1
Melikov, K.2
Brooks, H.3
Prevot, P.4
Lebleu, B.5
Chernomordik, L.V.6
-
50
-
-
11844268027
-
Cationic TAT peptide transduction domain enters cells by macropinocytosis
-
Kaplan IM, Wadia JS, Dowdy SF. Cationic TAT peptide transduction domain enters cells by macropinocytosis. J. Control. Release 102, 247-253 (2005).
-
(2005)
J. Control. Release
, vol.102
, pp. 247-253
-
-
Kaplan, I.M.1
Wadia, J.S.2
Dowdy, S.F.3
-
51
-
-
71749092534
-
Translocation and endocytosis for cell-penetrating peptide internalization
-
Jiao CY, Delaroche D, Burlina F, Alves ID, Chassaing G, Sagan S. Translocation and endocytosis for cell-penetrating peptide internalization. J. Biol. Chem. 284, 33957-33965 (2009).
-
(2009)
J. Biol. Chem
, vol.284
, pp. 33957-33965
-
-
Jiao, C.Y.1
Delaroche, D.2
Burlina, F.3
Alves, I.D.4
Chassaing, G.5
Sagan, S.6
-
52
-
-
33646343733
-
Membrane transduction of oligoarginine in HeLa cells is not mediated by macropinocytosis
-
Zaro JL, Rajapaksa TE, Okamoto CT, Shen WC. Membrane transduction of oligoarginine in HeLa cells is not mediated by macropinocytosis. Mol. Pharm. 3, 181-186 (2006).
-
(2006)
Mol. Pharm
, vol.3
, pp. 181-186
-
-
Zaro, J.L.1
Rajapaksa, T.E.2
Okamoto, C.T.3
Shen, W.C.4
-
53
-
-
0042232110
-
Studies on the internalization mechanism of cationic cell-penetrating peptides
-
Drin G, Cottin S, Blanc E, Rees AR, Temsamani J. Studies on the internalization mechanism of cationic cell-penetrating peptides. J. Biol. Chem. 278, 31192-31201 (2003) .
-
(2003)
J. Biol. Chem
, vol.278
, pp. 31192-31201
-
-
Drin, G.1
Cottin, S.2
Blanc, E.3
Rees, A.R.4
Temsamani, J.5
-
54
-
-
34250835903
-
A comprehensive model for the cellular uptake of cationic cell-penetrating peptides
-
Duchardt F, Fotin-Mleczek M, Schwarz H, Fischer R, Brock R. A comprehensive model for the cellular uptake of cationic cell-penetrating peptides. Traffic 8, 848-866 (2007).
-
(2007)
Traffic
, vol.8
, pp. 848-866
-
-
Duchardt, F.1
Fotin-Mleczek, M.2
Schwarz, H.3
Fischer, R.4
Brock, R.5
-
55
-
-
33748648777
-
Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells
-
Tunnemann G, Martin RM, Haupt S, Patsch C, Edenhofer F, Cardoso MC. Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells. FASEB J. 20, 1775-1784 (2006).
-
(2006)
FASEB J
, vol.20
, pp. 1775-1784
-
-
Tunnemann, G.1
Martin, R.M.2
Haupt, S.3
Patsch, C.4
Edenhofer, F.5
Cardoso, M.C.6
-
56
-
-
34247093930
-
Temperature-, concentration-and cholesterol-dependent translocation of l-and d-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells
-
Fretz MM, Penning NA, Al-Taei S et al. Temperature-, concentration-and cholesterol-dependent translocation of l-and d-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells. Biochem. J. 403, 335-342 (2007).
-
(2007)
Biochem. J
, vol.403
, pp. 335-342
-
-
Fretz, M.M.1
Penning, N.A.2
Al-Taei, S.3
-
57
-
-
63649127300
-
Cell entry of arginine-rich peptides is independent of endocytosis
-
Ter-Avetisyan G, Tunnemann G, Nowak D et al. Cell entry of arginine-rich peptides is independent of endocytosis. J. Biol. Chem. 284, 3370-3378 (2009).
-
(2009)
J. Biol. Chem
, vol.284
, pp. 3370-3378
-
-
Ter-Avetisyan, G.1
Tunnemann, G.2
Nowak, D.3
-
58
-
-
54849439914
-
Usefulness of cell-penetrating peptides to improve intestinal insulin absorption
-
Kamei N, Morishita M, Eda Y, Ida N, Nishio R, Takayama K. Usefulness of cell-penetrating peptides to improve intestinal insulin absorption. J. Control. Release 132, 21-25 (2008).
-
(2008)
J. Control. Release
, vol.132
, pp. 21-25
-
-
Kamei, N.1
Morishita, M.2
Eda, Y.3
Ida, N.4
Nishio, R.5
Takayama, K.6
-
59
-
-
0027173738
-
Epithelial transport of drugs in cell culture. VIII: Effects of sodium dodecyl sulfate on cell membrane and tight junction permeability in human intestinal epithelial (Caco-2) cells
-
Anderberg EK, Artursson P. Epithelial transport of drugs in cell culture. VIII: Effects of sodium dodecyl sulfate on cell membrane and tight junction permeability in human intestinal epithelial (Caco-2) cells. J. Pharm. Sci. 82, 392-398 (1993).
-
(1993)
J. Pharm. Sci
, vol.82
, pp. 392-398
-
-
Anderberg, E.K.1
Artursson, P.2
-
60
-
-
0033456147
-
Enhanced permeability of insulin across the rat intestinal membrane by various absorption enhancers: Their intestinal mucosal toxicity and absorption-enhancing mechanism of n-lauryl-beta-d-maltopyranoside
-
Uchiyama T, Sugiyama T, Quan YS et al. Enhanced permeability of insulin across the rat intestinal membrane by various absorption enhancers: their intestinal mucosal toxicity and absorption-enhancing mechanism of n-lauryl-beta-d-maltopyranoside. J. Pharm. Pharmacol. 51, 1241-1250 (1999).
-
(1999)
J. Pharm. Pharmacol
, vol.51
, pp. 1241-1250
-
-
Uchiyama, T.1
Sugiyama, T.2
Quan, Y.S.3
-
61
-
-
0034049590
-
Effects of some non-ionic surfactants on transepithelial permeability in Caco-2 cells
-
Dimitrijevic D, Shaw AJ, Florence AT. Effects of some non-ionic surfactants on transepithelial permeability in Caco-2 cells. J. Pharm. Pharmacol. 52, 157-162 (2000).
-
(2000)
J. Pharm. Pharmacol
, vol.52
, pp. 157-162
-
-
Dimitrijevic, D.1
Shaw, A.J.2
Florence, A.T.3
-
62
-
-
34248575520
-
Intranasal delivery: Physicochemical and therapeutic aspects
-
Costantino HR, Illum L, Brandt G et al. Intranasal delivery: Physicochemical and therapeutic aspects. Int. J. Pharm. 337, 1-24 (2007).
-
(2007)
Int. J. Pharm
, vol.337
, pp. 1-24
-
-
Costantino, H.R.1
Illum, L.2
Brandt, G.3
-
63
-
-
57349182296
-
Effect of cell-penetrating peptides on the nasal absorption of insulin
-
Khafagy El-S, Morishita M, Isowa K, Imai J, Takayama K. Effect of cell-penetrating peptides on the nasal absorption of insulin. J. Control. Release 133, 103-108 (2009).
-
(2009)
J. Control. Release
, vol.133
, pp. 103-108
-
-
El-S, K.1
Morishita, M.2
Isowa, K.3
Imai, J.4
Takayama, K.5
-
64
-
-
0025599403
-
Insulin and proinsulin proteolysis in mucosal homogenates of the albino rabbit: Implications in peptide delivery from nonoral routes
-
Yamamoto A, Hayakawa E, Lee VH. Insulin and proinsulin proteolysis in mucosal homogenates of the albino rabbit: implications in peptide delivery from nonoral routes. Life Sci. 47, 2465-2474 (1990).
-
(1990)
Life Sci
, vol.47
, pp. 2465-2474
-
-
Yamamoto, A.1
Hayakawa, E.2
Lee, V.H.3
-
65
-
-
67349268446
-
Importance of intermolecular interaction on the improvement of intestinal therapeutic peptide/protein absorption using cell-penetrating peptides
-
Kamei N, Morishita M, Takayama K. Importance of intermolecular interaction on the improvement of intestinal therapeutic peptide/protein absorption using cell-penetrating peptides. J. Control. Release 136, 179-186 (2009).
-
(2009)
J. Control. Release
, vol.136
, pp. 179-186
-
-
Kamei, N.1
Morishita, M.2
Takayama, K.3
-
66
-
-
76549110719
-
The role of intermolecular interactions with penetratin and its analogue on the enhancement of absorption of nasal therapeutic peptides
-
Khafagy El-S, Morishita M, Takayama K. The role of intermolecular interactions with penetratin and its analogue on the enhancement of absorption of nasal therapeutic peptides. Int. J. Pharm. 388, 209-212 (2010).
-
(2010)
Int. J. Pharm
, vol.388
, pp. 209-212
-
-
El-S, K.1
Morishita, M.2
Takayama, K.3
-
67
-
-
53049085052
-
Permeation characteristics of oligoarginine through intestinal epithelium and its usefulness for intestinal peptide drug delivery
-
Kamei N, Morishita M, Ehara J, Takayama K. Permeation characteristics of oligoarginine through intestinal epithelium and its usefulness for intestinal peptide drug delivery. J. Control. Release 131, 94-99 (2008).
-
(2008)
J. Control. Release
, vol.131
, pp. 94-99
-
-
Kamei, N.1
Morishita, M.2
Ehara, J.3
Takayama, K.4
-
68
-
-
1642374013
-
Membrane interaction and cellular internalization of penetratin peptides
-
Christiaens B, Grooten J, Reusens M et al. Membrane interaction and cellular internalization of penetratin peptides. Eur. J. Biochem. 271, 1187-1197 (2004).
-
(2004)
Eur. J. Biochem
, vol.271
, pp. 1187-1197
-
-
Christiaens, B.1
Grooten, J.2
Reusens, M.3
-
69
-
-
0034738570
-
Interaction of the third helix of Antennapedia homeodomain and a phospholipid monolayer, studied by ellipsometry and PM-IRRAS at the air-water interface
-
Bellet-Amalric E, Blaudez D, Desbat B, Graner F, Gauthier F, Renault A. Interaction of the third helix of Antennapedia homeodomain and a phospholipid monolayer, studied by ellipsometry and PM-IRRAS at the air-water interface. Biochim. Biophys. Acta 1467, 131-143 (2000).
-
(2000)
Biochim. Biophys. Acta
, vol.1467
, pp. 131-143
-
-
Bellet-Amalric, E.1
Blaudez, D.2
Desbat, B.3
Graner, F.4
Gauthier, F.5
Renault, A.6
-
70
-
-
0141942111
-
Membrane translocation of penetratin and its derivatives in different cell lines
-
Letoha T, Gaal S, Somlai C, Czajlik A, Perczel A, Penke B. Membrane translocation of penetratin and its derivatives in different cell lines. J. Mol. Recognit. 16, 272-279 (2003).
-
(2003)
J. Mol. Recognit
, vol.16
, pp. 272-279
-
-
Letoha, T.1
Gaal, S.2
Somlai, C.3
Czajlik, A.4
Perczel, A.5
Penke, B.6
-
71
-
-
44149128392
-
Stimulated endocytosis in penetratin uptake: Effect of arginine and lysine
-
Åmand HL, Fant K, Nordén B, Esbjörner EK. Stimulated endocytosis in penetratin uptake: effect of arginine and lysine. Biochem. Biophys. Res. Commun. 371, 621-625 (2008).
-
(2008)
Biochem. Biophys. Res. Commun
, vol.371
, pp. 621-625
-
-
Åmand, H.L.1
Fant, K.2
Nordén, B.3
Esbjörner, E.K.4
-
72
-
-
70349198899
-
Efficiency of cell-penetrating peptides on the nasal and intestinal absorption of therapeutic peptides and proteins
-
Khafagy El-S, Morishita M, Kamei N, Eda Y, Ikeno Y, Takayama K. Efficiency of cell-penetrating peptides on the nasal and intestinal absorption of therapeutic peptides and proteins. Int. J. Pharm. 381, 49-55 (2009).
-
(2009)
Int. J. Pharm
, vol.381
, pp. 49-55
-
-
El-S, K.1
Morishita, M.2
Kamei, N.3
Eda, Y.4
Ikeno, Y.5
Takayama, K.6
-
73
-
-
77952239068
-
Structural requirements of penetratin absorption enhancement efficiency for insulin delivery
-
Khafagy El-S, Morishita M, Ida N, Nishio R, Isowa K, Takayama K. Structural requirements of penetratin absorption enhancement efficiency for insulin delivery. J. Control. Release 143, 302-320(2010).
-
(2010)
J. Control. Release
, vol.143
, pp. 302-320
-
-
El-S, K.1
Morishita, M.2
Ida, N.3
Nishio, R.4
Isowa, K.5
Takayama, K.6
-
74
-
-
84872497161
-
Determination of the optimal cell-penetrating peptide sequence for intestinal insulin delivery based on molecular orbital analysis with self-organizing maps
-
Kamei N, Kikuchi S, Takeda-Morishita M et al. Determination of the optimal cell-penetrating peptide sequence for intestinal insulin delivery based on molecular orbital analysis with self-organizing maps. J. Pharm. Sci. 102(2), 469-479 (2012).
-
(2012)
J. Pharm. Sci
, vol.102
, Issue.2
, pp. 469-479
-
-
Kamei, N.1
Kikuchi, S.2
Takeda-Morishita, M.3
-
75
-
-
33847281527
-
A novel approach using functional peptides for efficient intestinal absorption of insulin
-
Morishita M, Kamei N, Ehara J, Isowa K, Takayama K. A novel approach using functional peptides for efficient intestinal absorption of insulin. J. Control. Release 118, 177-184 (2007).
-
(2007)
J. Control. Release
, vol.118
, pp. 177-184
-
-
Morishita, M.1
Kamei, N.2
Ehara, J.3
Isowa, K.4
Takayama, K.5
-
76
-
-
77955269563
-
Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography
-
Kamei N, Morishita M, Kanayama Y et al. Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography. J. Control. Release 146, 16-22 (2010).
-
(2010)
J. Control. Release
, vol.146
, pp. 16-22
-
-
Kamei, N.1
Morishita, M.2
Kanayama, Y.3
|