Determination of the optimal cell-penetrating peptide sequence for intestinal insulin delivery based on molecular orbital analysis with self-organizing maps

Journal of Pharmaceutical Sciences

Volumn 102, Issue 2, 2013, Pages 469-479

  Kamei, Noriyasu ^a   Kikuchi, Shingo ^b   Takeda Morishita, Mariko ^a   Terasawa, Yoshiaki ^b   Yasuda, Akihito ^b   Yamamoto, Shuichi ^b   Ida, Nobuo ^c   Nishio, Reiji ^c   Takayama, Kozo ^b  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b HOSHI UNIVERSITY   (Japan)

^c TORAY INDUSTRIES INC   (Japan)

Author keywords

Absorption enhancer; Bioavailability; Cell penetrating peptide; Insulin; Intestinal absorption; Molecular orbital analysis; Multivariate analysis; Penetratin; Self organizing map; Simulations

Indexed keywords

CELL PENETRATING PEPTIDE; INSULIN; PENETRATIN;

AMINO ACID SEQUENCE; ARTICLE; DRUG DELIVERY SYSTEM; HARDNESS; HYDROPHOBICITY; INTESTINE ABSORPTION; METHODOLOGY; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY;

EID: 84872497161     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23364     Document Type: Article

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