The effect of oral absorption enhancers on the in vivo performance of insulin-loaded poly(ethylcyanoacrylate) nanospheres in diabetic rats

Journal of Microencapsulation

Volumn 19, Issue 2, 2002, Pages 225-235

  Radwan, M A ^a   Aboul Enein, H Y ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

Capric acid; Cholic acid; Deoxycholic acid; Glycyrrhizic acid; Hydroxypropyl cyclodextrin; Insulin; Nanospheres; Poly(ethylcyanoacrylate

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; BILE SALT; CHOLIC ACID; CYANOACRYLATE DERIVATIVE; DECANOIC ACID; DEOXYCHOLATE SODIUM; DEOXYCHOLIC ACID; DRUG CARRIER; ENZYME INHIBITOR; GLUCOSE; GLYCYRRHIZIC ACID; INSULIN; NANOPARTICLE; POLOXAMER; POLY(ETHYL 2 CYANOACRYLATE); PROTEINASE INHIBITOR; STREPTOZOCIN; CYACRIN; MICROSPHERE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG HALF LIFE; DRUG SYNTHESIS; GLUCOSE BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOGLYCEMIA; IN VIVO STUDY; MALE; NONHUMAN; PH; PHYSICAL PHASE; POLYMERIZATION; RAT; STREPTOZOCIN DIABETES; ANIMAL; BIOAVAILABILITY; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DIABETES MELLITUS; DISEASE MODEL; DRUG SCREENING; METHODOLOGY; NANOTECHNOLOGY; ORAL DRUG ADMINISTRATION; STANDARD;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; BLOOD GLUCOSE; CYANOACRYLATES; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; INSULIN; MICROSPHERES; NANOTECHNOLOGY; RATS; STREPTOZOCIN;

EID: 0036156214     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652040110081406     Document Type: Article

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