Challenges for the oral delivery of macromolecules

Nature Reviews Drug Discovery

Volumn 2, Issue 4, 2003, Pages 289-295

  Goldberg, Michael ^a   Gomez Orellana, Isabel ^a  

^a Emisphere Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; CROMOGLYCATE DISODIUM; CYCLOSPORIN; GLUCOSE; HEPARIN; INSULIN DERIVATIVE; LOW MOLECULAR WEIGHT HEPARIN; PARATHYROID HORMONE; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN;

CELL MEMBRANE PERMEABILITY; CHEMICAL MODIFICATION; CLINICAL TRIAL; DIABETES MELLITUS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; DRUG INDUSTRY; DRUG RESEARCH; DRUG STRUCTURE; DRUG TRANSPORT; GLUCOSE BLOOD LEVEL; HUMAN; HYDROPHILICITY; LIPOPHILICITY; MACROMOLECULE; MICROEMULSION; MOLECULAR WEIGHT; PRIORITY JOURNAL; REVIEW; STEADY STATE; TIGHT JUNCTION; ANIMAL; BIOAVAILABILITY; FORECASTING; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; FORECASTING; HEPARIN; HUMANS; MACROMOLECULAR SUBSTANCES; RECOMBINANT PROTEINS;

EID: 0037393955     PISSN: 14741776     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrd1067     Document Type: Review

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