A novel approach using functional peptides for efficient intestinal absorption of insulin

Journal of Controlled Release

Volumn 118, Issue 2, 2007, Pages 177-184

  Morishita, Mariko ^a   Kamei, Noriyasu ^a   Ehara, Jumpei ^a   Isowa, Koichi ^b   Takayama, Kozo ^a  

^a HOSHI UNIVERSITY   (Japan)

^b The Center of Japan Biological Chemistry Co Ltd   (Japan)

Author keywords

Cell penetrating peptide (CPP); Drug delivery; Insulin; Intestinal absorption; Oligoarginine

Indexed keywords

CELL-PENETRATING PEPTIDE (CPP); CELLULAR INTEGRITY; DEHYDROGENASE LEAKAGE; INTESTINAL ABSORPTION; OLIGOARGININE;

CELL MEMBRANES; CONTROLLED DRUG DELIVERY; INSULIN; INTERFERONS; MACROMOLECULES;

AMINO ACIDS;

ARGININE DERIVATIVE; OLIGOARGININE; OXIDOREDUCTASE; RECOMBINANT HUMAN INSULIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG EFFECT; HYDROPHILICITY; INTESTINE ABSORPTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE INJURY;

ADMINISTRATION, ORAL; ANIMALS; ARGININE; BLOOD GLUCOSE; DEXTRANS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCEIN-5-ISOTHIOCYANATE; HYPOGLYCEMIC AGENTS; ILEUM; INJECTIONS, SUBCUTANEOUS; INSULIN; INTERFERON-BETA; INTESTINAL ABSORPTION; MALE; MOLECULAR STRUCTURE; OLIGOPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; TIME FACTORS;

EID: 33847281527     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.12.022     Document Type: Article

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