Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Yadav, Umesh C S ^a   Naura, Amarjit S ^b   Aguilera Aguirre, Leopoldo ^a   Boldogh, Istvan ^a   Boulares, Hamid A ^b   Calhoun, William J ^c   Ramana, Kota V ^a   Srivastava, Satish K ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; DRINKING WATER; FIBRONECTIN; FIDARESTAT; GELATINASE A; GLYCOGEN SYNTHASE KINASE 3BETA; METHACHOLINE; MITOGEN ACTIVATED PROTEIN KINASE; OCCLUDIN; OVALBUMIN; PHOSPHATIDYLINOSITOL 3 KINASE; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN;

AIRWAY REMODELING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; GOBLET CELL; HUMAN; HUMAN CELL; INFLAMMATORY INFILTRATE; LUNG FIBROBLAST; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM;

AIRWAY REMODELING; ALDEHYDE REDUCTASE; ANIMALS; ASTHMA; BIOLOGICAL MARKERS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; HYPERSENSITIVITY; IMIDAZOLIDINES; INFLAMMATION; LUNG; METAPLASIA; MICE; MUCUS; OVALBUMIN; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84874519433     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057442     Document Type: Article

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