Aldose Reductase Inhibition Prevents Metaplasia of Airway Epithelial Cells

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Yadav, Umesh C S ^a   Aguilera Aguirre, Leopoldo ^a   Ramana, Kota V ^a   Boldogh, Istvan ^a   Srivastava, Satish K ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; FIDARESTAT; INTERLEUKIN 13; JANUS KINASE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUCIN 5AC; MUCIN 5B; RAGWEED ANTIGEN; REACTIVE OXYGEN METABOLITE; SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ENZYME INHIBITOR; STAT6 PROTEIN, HUMAN; STAT6 PROTEIN, MOUSE;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GOBLET CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; METAPLASIA; MOUSE; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; TH2 CELL; UPREGULATION; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; EPITHELIUM CELL; LUNG; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY;

AMBROSIA; MUS;

ALDEHYDE REDUCTASE; ANIMALS; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL CELLS; GOBLET CELLS; HUMANS; INTERLEUKIN-13; LUNG; METAPLASIA; MICE; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; STAT6 TRANSCRIPTION FACTOR;

EID: 78650817706     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014440     Document Type: Article

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