메뉴 건너뛰기




Volumn 40, Issue 1, 2012, Pages 240-245

Targeting phosphoinositide 3-kinase δ for allergic asthma

Author keywords

Allergic asthma; B cell; Cytokine; Mast cell; Phosphoinositide 3 kinase (PI3K); T cell

Indexed keywords

CORTICOSTEROID; CYCLOSPORIN A; MEPOLIZUMAB; MONTELUKAST; OMALIZUMAB; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR;

EID: 84863073430     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20110665     Document Type: Review
Times cited : (45)

References (26)
  • 1
    • 77955912801 scopus 로고    scopus 로고
    • Clinical practice: Emergency treatment of asthma
    • Lazarus, S.C. (2010) Clinical practice: emergency treatment of asthma. N. Engl. J. Med. 363, 755-764
    • (2010) N. Engl. J. Med. , vol.363 , pp. 755-764
    • Lazarus, S.C.1
  • 2
    • 0033060552 scopus 로고    scopus 로고
    • How much asthma is really attributable to atopy?
    • Pearce, N., Pekkanen, J. and Beasley, R. (1999) How much asthma is really attributable to atopy? Thorax 54, 268-272 (Pubitemid 29110510)
    • (1999) Thorax , vol.54 , Issue.3 , pp. 268-272
    • Pearce, N.1    Pekkanen, J.2    Beasley, R.3
  • 3
    • 0030943398 scopus 로고    scopus 로고
    • T cell antigen receptor signal transduction
    • DOI 10.1016/S0955-0674(97)80064-6
    • Qian, D. and Weiss, A. (1997) T cell antigen receptor signal transduction. Curr. Opin. Cell. Biol. 9, 205-212 (Pubitemid 27135988)
    • (1997) Current Opinion in Cell Biology , vol.9 , Issue.2 , pp. 205-212
    • Qian, D.1    Weiss, A.2
  • 4
    • 47949119866 scopus 로고    scopus 로고
    • Pathogenesis of asthma
    • Holgate, S.T. (2008) Pathogenesis of asthma. Clin. Exp. Allergy 38, 872-897
    • (2008) Clin. Exp. Allergy , vol.38 , pp. 872-897
    • Holgate, S.T.1
  • 5
    • 0026529218 scopus 로고
    • Trial of cyclosporin in corticosteroid-dependent chronic severe asthma
    • Alexander, A.G., Barnes, N.C. and Kay, A.B. (1992) Trial of cyclosporin in corticosteroid-dependent chronic severe asthma. Lancet 339, 324-328
    • (1992) Lancet , vol.339 , pp. 324-328
    • Alexander, A.G.1    Barnes, N.C.2    Kay, A.B.3
  • 11
    • 0038549067 scopus 로고    scopus 로고
    • PI3K in lymphocyte development, differentiation and activation
    • Okkenhaug, K. and Vanhaesebroeck, B. (2003) PI3K in lymphocyte development, differentiation and activation. Nat. Rev. Immunol. 3, 317-330 (Pubitemid 37328684)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.4 , pp. 317-330
    • Okkenhaug, K.1    Vanhaesebroeck, B.2
  • 12
    • 33846621025 scopus 로고    scopus 로고
    • Antigen receptor signalling: A distinctive role for the p110δ isoform of PI3K
    • DOI 10.1016/j.it.2006.12.007, PII S147149060600353X
    • Okkenhaug, K., Ali, K. and Vanhaesebroeck, B. (2007) Antigen receptor signalling: a distinctive role for the p110δ isoform of PI3K. Trends Immunol. 28, 80-87 (Pubitemid 46176736)
    • (2007) Trends in Immunology , vol.28 , Issue.2 , pp. 80-87
    • Okkenhaug, K.1    Ali, K.2    Vanhaesebroeck, B.3
  • 15
    • 84863034751 scopus 로고    scopus 로고
    • Inhibitors of human phosphatidyl-inositol 3-kinase δ
    • Int. Pat. WO 2001/81346
    • Sadhu, C., Dick, K., Treiberg, J., Sowell, C., Kesicki, E.A. and Oliver, A. (2001) Inhibitors of human phosphatidyl-inositol 3-kinase δ. Int. Pat. WO 2001/81346
    • (2001)
    • Sadhu, C.1    Dick, K.2    Treiberg, J.3    Sowell, C.4    Kesicki, E.A.5    Oliver, A.6
  • 18
    • 11144354388 scopus 로고    scopus 로고
    • Mechanisms and implications of phosphoinositide 3-kinase δ in promoting neutrophil trafficking into inflamed tissue
    • DOI 10.1182/blood-2003-05-1667
    • Puri, K.D., Doggett, T.A., Douangpanya, J., Hou, Y., Tino, W.T., Wilson, T., Graf, T., Clayton, E., Turner, M., Hayflick, J.S. and Diacovo, T.G (2004) Mechanisms and implications of phosphoinositide 3-kinase δ in promoting neutrophil trafficking into inflamed tissue. Blood 103, 3448-3456 (Pubitemid 38525677)
    • (2004) Blood , vol.103 , Issue.9 , pp. 3448-3456
    • Puri, K.D.1    Doggett, T.A.2    Douangpanya, J.3    Hou, Y.4    Tino, W.T.5    Wilson, T.6    Graf, T.7    Clayton, E.8    Turner, M.9    Hayflick, J.S.10    Diacovo, T.G.11
  • 19
    • 33746581368 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase-δ inhibitor reduces vascular permeability in a murine model of asthma
    • DOI 10.1016/j.jaci.2006.04.041, PII S0091674906009341
    • Lee, K.S., Park, S.J., Kim, S.R., Min, K.H., Jin, S.M., Puri, K.D. and Lee, Y.C. (2006) Phosphoinositide 3-kinase-δ inhibitor reduces vascular permeability in a murine model of asthma. J. Allergy Clin. Immunol. 118, 403-409 (Pubitemid 44142718)
    • (2006) Journal of Allergy and Clinical Immunology , vol.118 , Issue.2 , pp. 403-409
    • Lee, K.S.1    Park, S.J.2    Kim, S.R.3    Min, K.H.4    Jin, S.M.5    Puri, K.D.6    Lee, Y.C.7
  • 20
    • 30444439101 scopus 로고    scopus 로고
    • Key role of the p110δ isoform of PI3K in B-cell antigen and IL-4 receptor signaling: Comparative analysis of genetic and pharmacologic interference with p110δ function in B cells
    • DOI 10.1182/blood-2005-07-3041
    • Bilancio, A., Okkenhaug, K., Camps, M., Emery, J.L., Ruckle, T., Rommel, C. and Vanhaesebroeck, B. (2006) Key role of the p110δ isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110δ function in B cells. Blood 107, 642-650 (Pubitemid 43076389)
    • (2006) Blood , vol.107 , Issue.2 , pp. 642-650
    • Bilancio, A.1    Okkenhaug, K.2    Camps, M.3    Emery, J.L.4    Ruckle, T.5    Rommel, C.6    Vanhaesebroeck, B.7
  • 21
    • 33846926759 scopus 로고    scopus 로고
    • Requirement for phosphoinositide 3-kinase p110δ signaling in B cell antigen receptor-mediated antigen presentation
    • Al-Alwan, M.M., Okkenhaug, K., Vanhaesebroeck, B., Hayflick, J.S. and Marshal, A.J. (2007) Requirement for phosphoinositide 3-kinase p110δsignaling in B cell antigen receptor-mediated antigen presentation. J. Immunol. 178, 2328-2335 (Pubitemid 46233431)
    • (2007) Journal of Immunology , vol.178 , Issue.4 , pp. 2328-2335
    • Al-Alwan, M.M.1    Okkenhaug, K.2    Vanhaesebroeck, B.3    Hayflick, J.S.4    Marshal, A.J.5
  • 22
  • 23
    • 33645827963 scopus 로고    scopus 로고
    • Inhibition of phosphoinositide 3-kinase δ attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model
    • DOI 10.1096/fj.05-5045com
    • Lee, K.S., Lee, H.K., Hayflick, J.S., Lee, Y.C. and Puri, K.D. (2006) Inhibition of phosphoinositide 3-kinase δ attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model. FASEB J. 20, 455-465 (Pubitemid 44933322)
    • (2006) FASEB Journal , vol.20 , Issue.3 , pp. 455-465
    • Lee, K.S.1    Lee, H.K.2    Hayflick, J.S.3    Lee, Y.C.4    Puri, K.D.5
  • 26
    • 77951667667 scopus 로고    scopus 로고
    • A role for phosphoinositol 3-kinase δ in the impairment of glucocorticoid responsiveness in patients with chronic obstructive pulmonary disease
    • Marwick, J.A., Caramori, G., Casolari, P., Mazzoni, F., Kirkham, P.A., Adcock, I.M., Chung, K.F. and Papi, A. (2010) A role for phosphoinositol 3-kinase δ in the impairment of glucocorticoid responsiveness in patients with chronic obstructive pulmonary disease. J. Allergy Clin. Immunol. 125, 1146-1153
    • (2010) J. Allergy Clin. Immunol. , vol.125 , pp. 1146-1153
    • Marwick, J.A.1    Caramori, G.2    Casolari, P.3    Mazzoni, F.4    Kirkham, P.A.5    Adcock, I.M.6    Chung, K.F.7    Papi, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.