DNA methylation in cancer: A gene silencing mechanism and the clinical potential of its biomarkers

Tohoku Journal of Experimental Medicine

Volumn 229, Issue 3, 2013, Pages 173-185

  Fukushige, Shinichi ^a   Horii, Akira ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Biomarker; Cancer; CpG island; DNA methylation; Gene silencing

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; GLUTATHIONE TRANSFERASE P1; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PLACENTA PROTEIN 5; PROTEIN P16; TUMOR MARKER;

CANCER PREVENTION; CANCER PROGNOSIS; CANCER RISK; CARCINOGENESIS; DNA METHYLATION; EARLY DIAGNOSIS; EPIGENETICS; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE SILENCING; GLUTATHIONE S TRANSFERASE PI 1 GENE; H CADHERIN GENE; HUMAN; MUTATIONAL ANALYSIS; NONHUMAN; O6 METHYLGUANINE DNA METHYLTRANSFERASE GENE; OXIDATION KINETICS; P16 GENE; PROMOTER REGION; REVIEW; RISK ASSESSMENT; SEPTIN 9 GENE; TISSUE FACTOR PATHWAY INHIBITOR 2 GENE; TUMOR GENE;

ANIMALS; BASE SEQUENCE; CELL TRANSFORMATION, NEOPLASTIC; DNA METHYLATION; GENE SILENCING; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASMS; PROMOTER REGIONS, GENETIC; TUMOR MARKERS, BIOLOGICAL;

EID: 84874198889     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.229.173     Document Type: Review

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