Methyl-CpG targeted recruitment of p300 reactivates tumor suppressor genes in human cancer cells

Biochemical and Biophysical Research Communications

Volumn 379, Issue 4, 2009, Pages 1021-1026

  Fukushige, Shinichi ^a   Kondo, Emiko ^a   Horii, Akira ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CpG island; Histone modification; MBD; MeTA; NF B; p300; Transcriptional activation domain; Transcriptional repression; Tumor suppressor gene

Indexed keywords

PROTEIN MLH1; PROTEIN P300;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN LNCAP; CPG ISLAND; EPIGENETICS; FEMALE; GENE ACTIVATION; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MALE; METHYLATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; TUMOR SUPPRESSOR GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE, TUMOR; CPG ISLANDS; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, TUMOR SUPPRESSOR; HUMANS; NEOPLASMS; NUCLEAR PROTEINS; P300-CBP TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, TERTIARY;

EID: 58949096479     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.01.010     Document Type: Article

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