Random partitioning of molecules at cell division

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 36, 2011, Pages 15004-15009

  Huh, Dann ^a,b   Paulsson, Johan ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL DIVISION; CELL HETEROGENEITY; MOLECULAR BIOLOGY; MOLECULAR PARTITIONING; NONHUMAN; PRIORITY JOURNAL; RANDOM ERROR;

CELL DIVISION; MODELS, BIOLOGICAL;

EID: 80052565008     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1013171108     Document Type: Article

References (52)

1. Warren G (1993) Membrane partitioning during cell division. Annu Rev Biochem 62: 323-348.
2. Marshall WF (2007) Stability and robustness of an organelle number control system: Modeling and measuring homeostatic regulation of centriole abundance. Biophys J 93:1818-1833.
3. Birky CW, Jr. (1983) The partitioning of cytoplasmic organelles at cell division. Int Rev Cytol Suppl 15:49-89.
4. Nordström K, Austin SJ (1989) Mechanisms that contribute to the stable segregation of plasmids. Annu Rev Genet 23:37-69. (Pubitemid 20033396)
5. Ozbudak EM, Thattai M, Kurtser I, Grossman AD, Van Oudenaarden A (2002) Regulation of noise in the expression of a single gene. Nat Genet 31:69-73.
6. Golding I, Paulsson J, Zawilski SM, Cox EC (2005) Real-time kinetics of gene activity in individual bacteria. Cell 123:1025-1036. (Pubitemid 41785418)
7. Elowitz MB, Levine AJ, Siggia ED, Swain PS (2002) Stochastic gene expression in a single cell. Science 297:1183-1186. (Pubitemid 36193353)
8. Raj A, Rifkin SA, Andersen E, Van Oudenaarden A (2010) Variability in gene expression underlies incomplete penetrance. Nature 463:913-918.
9. Becskei A, Serrano L (2000) Engineering stability in gene networks by autoregulation. Nature 405:590-593.
10. Süel GM, Garcia-Ojalvo J, Liberman LM, Elowitz MB (2006) An excitable gene regulatory circuit induces transient cellular differentiation. Nature 440:545-550.
11. Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK (2009) Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 459:428-432.
12. Yu J, Xiao J, Ren X, Lao K, Xie XS (2006) Probing gene expression in live cells, one protein molecule at a time. Science 311:1600-1603.
13. Cai L, Friedman N, Xie XS (2006) Stochastic protein expression in individual cells at the single molecule level. Nature 440:358-362.
14. Huh D, Paulsson J (2011) Non-genetic heterogeneity from stochastic partitioning at cell division. Nat Genet 43:95-100.
15. Weiss M, Elsner M, Kartberg F, Nilsson T (2004) Anomalous subdiffusion is a measure for cytoplasmic crowding in living cells. Biophys J 87:3518-3524. (Pubitemid 40468604)
16. Kulkarni RP, Castelino K, Majumdar A, Fraser SE (2006) Intracellular transport dynamics of endosomes containing DNA polyplexes along the microtubule network. Biophys J 90:L42-L44.
17. Golding I, Cox EC (2006) Physical nature of bacterial cytoplasm. Phys Rev Lett 96: 098102.
18. Bergeland T, Widerberg J, Bakke O, Nordeng TW (2001) Mitotic partitioning of endosomes and lysosomes. Curr Biol 11:644-651. (Pubitemid 32418160)
19. McAuley PJ (1990) Partitioning of symbiotic Chlorella at host cell telophase in the green hydra symbiosis. Philos Trans R Soc Lond B Biol Sci 329:47-53.
20. Rosenfeld N, Young JW, Alon U, Swain PS, Elowitz MB (2005) Gene regulation at the single-cell level. Science 307:1962-1965. (Pubitemid 40404705)
21. Brenner N, Farkash K, Braun E (2006) Dynamics of protein distributions in cell populations. Phys Biol 3:172-182. (Pubitemid 44773312)
22. Berg OG (1978) A model for the statistical fluctuations of protein numbers in a microbial population. J Theor Biol 71:587-603.
23. Rigney DR (1979) Stochastic model of constitutive protein levels in growing and dividing bacterial cells. J Theor Biol 76:453-480.
24. Paulsson J, Ehrenberg M (2001) Noise in a minimal regulatory network: Plasmid copy number control. Q Rev Biophys 34:1-59. (Pubitemid 32510203)
25. Swain PS, Elowitz MB, Siggia ED (2002) Intrinsic and extrinsic contributions to stochasticity in gene expression. Proc Natl Acad Sci USA 99:12795-12800.
26. Rausenberger J, Kollmann M (2008) Quantifying origins of cell-to-cell variations in gene expression. Biophys J 95:4523-4528.
27. Tyson JJ (1989) Effects of asymmetric division on a stochastic model of the cell division cycle. Math Biosci 96:165-184.
28. Nanninga N, Koppes LJH, De Vries-Tijssen FC (1979) The cell cycle of Bacillus subtilis as studied by electron microscopy. Arch Microbiol 123:173-181. (Pubitemid 10201297)
29. Trueba FJ (1982) On the precision and accuracy achieved by Escherichia coli cells at fission about their middle. Arch Microbiol 131:55-59.
30. Raser JM, O'Shea EK (2004) Control of stochasticity in eukaryotic gene expression. Science 304:1811-1814. (Pubitemid 38787899)
31. Raskin DM, De Boer PA (1999) Rapid pole-to-pole oscillation of a protein required for directing division to the middle of Escherichia coli. Proc Natl Acad Sci USA 96: 4971-4976. (Pubitemid 29214520)
32. Juarez JR, Margolin W (2010) Changes in the Min oscillation pattern before and after cell birth. J Bacteriol 192:4134-4142.
33. Di Ventura B, Sourjik V (2011) Self-organized partitioning of dynamically localized proteins in bacterial cell division. Mol Syst Biol 7:457.
34. Birky CW, Skavaril RV (1984) Random partitioning of cytoplasmic organelles at cell division: The effect of organelle and cell volume. J Theor Biol 106:441-447. (Pubitemid 14114122)
35. Shima DT, Cabrera-Poch N, Pepperkok R, Warren G (1998) An ordered inheritance strategy for the Golgi apparatus: Visualization of mitotic disassembly reveals a role for the mitotic spindle. J Cell Biol 141:955-966. (Pubitemid 28243963)
36. Møller-Jensen J, et al. (2003) Bacterial mitosis: ParM of plasmid R1 moves plasmid DNA by an actin-like insertional polymerization mechanism. Mol Cell 12:1477-1487. (Pubitemid 38037016)
37. Garner EC, Campbell CS, Weibel DB, Mullins RD (2007) Reconstitution of DNA segregation driven by assembly of a prokaryotic actin homolog. Science 315:1270-1274. (Pubitemid 46364263)
38. Sheahan MB, Rose RJ, McCurdy DW (2004) Organelle inheritance in plant cell division: The actin cytoskeleton is required for unbiased inheritance of chloroplasts, mitochondria and endoplasmic reticulum in dividing protoplasts. Plant J 37:379-390. (Pubitemid 38192964)
39. Wilson EB (1916) The distribution of the chondriosomes to the spermatozoa in scorpions. Proc Natl Acad Sci USA 2:321-324.
40. Wilson EB (1931) The distribution of sperm-forming materials in scorpions. J Morphol Physiol 52:429-483.
41. Hood RD, Watson OF, Deason TR, Benton CLB, Jr. (1972) Ultrastructure of scorpion spermatozoa with atypical axonemes. Cytobios 5:167-177.
42. Shima DT, Haldar K, Pepperkok R, Watson R, Warren G (1997) Partitioning of the Golgi apparatus during mitosis in living HeLa cells. J Cell Biol 137:1211-1228. (Pubitemid 27265937)
43. Hennis AS, Birky CW, Jr. (1984) Stochastic partitioning of chloroplasts at cell division in the alga Olisthodiscus, and compensating control of chloroplast replication. J Cell Sci 70:1-15.
44. Blower MD, Feric E, Weis K, Heald R (2007) Genome-wide analysis demonstrates conserved localization of messenger RNAs to mitotic microtubules. J Cell Biol 179: 1365-1373.
45. Savage DF, Afonso B, Chen AH, Silver PA (2010) Spatially ordered dynamics of the bacterial carbon fixation machinery. Science 327:1258-1261.
46. Paulsson J (2004) Summing up the noise in gene networks. Nature 427:415-418.
47. Motley AM, Hettema EH (2007) Yeast peroxisomes multiply by growth and division. J Cell Biol 178:399-410. (Pubitemid 47196149)
48. Marshall WF, Vucica Y, Rosenbaum JL (2001) Kinetics and regulation of de novo centriole assembly. Implications for the mechanism of centriole duplication. Curr Biol 11:308-317. (Pubitemid 32200733)
49. Neidhardt FC (1996) Escherichia coli and Salmonella: Cellular and Molecular Biology (American Society for Microbiology, Washington, DC), p 123.
50. Doerder FP (1979) Regulation of macronuclear DNA content in Tetrahymena thermophila. J Protozool 26:28-35.
51. Berger JD (1979) Regulation of macronuclear DNA content in Paramecium tetraurelia. J Protozool 26:18-28.
52. Huang B, et al. (2007) Counting low-copy number proteins in a single cell. Science 315: 81-84. (Pubitemid 46196982)