Synchronous and stochastic patterns of gene activation in the drosophila embryo

Science

Volumn 325, Issue 5939, 2009, Pages 471-473

  Boettiger, Alistair N ^a   Levine, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; MYOCYTE ENHANCER FACTOR 2; RNA POLYMERASE II;

EMBRYONIC DEVELOPMENT; ENZYME ACTIVITY; FLY; GENE EXPRESSION; HYBRIDIZATION; PROTEIN; RNA; STOCHASTICITY; SYNCHRONY;

ARTICLE; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; GENE; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETIC TRANSCRIPTION; HEARTBROKEN GENE; HEARTLESS GENE; IN SITU HYBRIDIZATION; MDR49 GENE; MES4 GENE; NONHUMAN; PANNIER GENE; PRIORITY JOURNAL; PROMOTER REGION; STUMPS GENE; U SHAPED GEN;

ANIMALS; DROSOPHILA; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; RNA POLYMERASE II; STOCHASTIC PROCESSES; TRANSCRIPTIONAL ACTIVATION;

EID: 67749106610     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1173976     Document Type: Article

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39. We thank P. Ralph and S. Evans for help with constructing and analyzing the mathematical models of Pol II elongation and initiation that motivated our hypothesis about the synchrony of gene expression. A.N.B. is supported by NSF Graduate Research Fellowship Program. This study was funded by a grant from NIH (GM34431).