Tautomeric origin of dual effects of N1-nicotinoyl-3-(4′-hydroxy- 3′-methyl phenyl)-5-[(sub)phenyl]-2-pyrazolines on bacterial and viral strains: POM analyses as new efficient bioinformatics' platform to predict and optimize bioactivity of drugs

Medicinal Chemistry Research

Volumn 22, Issue 3, 2013, Pages 1438-1449

  Hadda, Taibi Ben ^a   Ali, Mohamed A ^b,g   Masand, Vijay ^c   Gharby, Said ^d   Fergoug, Teffaha ^e   Warad, Ismail ^f  

^a FACULTÉ DES SCIENCES   (Morocco)

^b Sunrise University   (India)

^c Vidya Bharati College   (India)

^d FACULTÉ DES SCIENCES   (Morocco)

^e UNIVERSITÉ DE MASCARA   (Algeria)

^f KING SAUD UNIVERSITY   (Saudi Arabia)

^g INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE INFORMM   (Malaysia)

Author keywords

2 Pyrazolines; Petra Osiris Molinspiration (POM); Tautomerism; Virtual screening

Indexed keywords

2 PYRAZOLINE DERIVATIVE; ANTIBIOTIC AGENT; ANTIVIRUS AGENT; FLUCONAZOLE; NEVIRAPINE; OFLOXACIN; PYRAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BIOINFORMATICS; CONTROLLED STUDY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; HYDROPHOBICITY; ISOMERIZATION; LIPOPHILICITY; NONHUMAN; PHARMACOPHORE; PREDICTIVE VALUE; STATIC ELECTRICITY; STEREOCHEMISTRY; TAUTOMER; TAUTOMERIZATION; VIRUS STRAIN;

EID: 84874106020     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0143-6     Document Type: Article

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