Identification of antibacterial and antifungal pharmacophore sites for potent bacteria and fungi inhibition: Indolenyl sulfonamide derivatives

European Journal of Medicinal Chemistry

Volumn 45, Issue 3, 2010, Pages 1189-1199

  Chohan, Zahid H ^a   Youssoufi, Moulay H ^b   Jarrahpour, Aliasghar ^c   Ben Hadda, Taibi ^b  

^a BAHAUDDIN ZAKARIYA UNIVERSITY   (Pakistan)

^b FACULTÉ DES SCIENCES   (Morocco)

^c SHIRAZ UNIVERSITY   (Iran)

Author keywords

Antibacterial; Antifungal; Bioinformatics; Cytotoxicity; Indolenyl sulfonamide; Molinspiration; Osiris; Petra; Virtual screening

Indexed keywords

4 [(1H INDOLE 3 YLMETHYLENE)AMINO] BENZENESULFONAMIDE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; METAL ION; N (3,4 DIMETHYLISOXAZOL 5 YL) 4 [(1H INDOL 3 YLMETHYLENE)AMINO]BENZENESULFONAMIDE; N (4,6 DIMETHYLPYRIMIDIN 2 YL) 4 [(1H INDOL 3 YLMETHYLENE)AMINO]BENZENESULFONAMIDE; N (5 METHYLISOXAZOL 3 YL) 4 [(1H INDOL 3 YLMETHYLENE)AMINO]BENZENESULFONAMIDE; N (PYRIMIDIN 2 YL) 4 [(1H INDOL 3 YLMETHYLENE)AMINO]BENZENESULFONAMIDE; N (THIAZOLE 2 YL) 4 [(1H INDOL 3 YLMETHYLENE)AMINO]BENZENESULFONAMIDE; N CARBAMIMIDOYL 4 [(1H INDOL 3 YLMETHYLENE)AMINO]BENZENESULFONAMIDE; SULFADIAZINE; SULFADIMIDINE; SULFAFURAZOLE; SULFAGUANIDINE; SULFAMETHOXAZOLE; SULFANILAMIDE; SULFATHIAZOLE; SULFONAMIDE; TRANSITION ELEMENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTEMIA; ARTICLE; ASPERGILLUS FLAVUS; BACILLUS SUBTILIS; BIOASSAY; CANDIDA ALBICANS; CANDIDA GLABRATA; CARBON NUCLEAR MAGNETIC RESONANCE; COMPETITIVE INHIBITION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SYNTHESIS; ESCHERICHIA COLI; FUSARIUM; IN VITRO STUDY; INFRARED SPECTROSCOPY; MICROSPORUM CANIS; NONHUMAN; PHARMACOPHORE; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHI; SHIGELLA FLEXNERI; STAPHYLOCOCCUS AUREUS; TRICHOPHYTON; ULTRAVIOLET RADIATION;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; BINDING SITES; FUNGI; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SULFONAMIDES;

EID: 76049104501     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.11.029     Document Type: Article

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