Synthesis and in vitro antimycobacterial activity of N1-nicotinoyl-3-(4′-hydroxy-3′-methyl phenyl)-5-[(sub)phenyl]-2-pyrazolines

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 15, 2006, Pages 3947-3949

  Shaharyar, Mohammad ^a   Siddiqui, Anees Ahamed ^a   Ali, Mohamed Ashraf ^a   Sriram, Dharmarajan ^b   Yogeeswari, Perumal ^b  

^a HAMDARD UNIVERSITY   (India)

^b BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Antimycobacterial activity; Pyrazolines

Indexed keywords

ANTIMYCOBACTERIAL AGENT; CHALCONE DERIVATIVE; ISONIAZID; N 1 NICOTINYL 3 (4' HYDROXY 3' METHYLPHENYL) 5 (1'' CHLOROPHENYL) 2 PYRAZOLINE; PYRAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CHEMICAL REACTION; CONTROLLED STUDY; DILUTION; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

ANIMALS; ANTITUBERCULAR AGENTS; CERCOPITHECUS AETHIOPS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PYRAZOLES; VERO CELLS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 33745180244     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.05.024     Document Type: Article

References (11)

1. Bloom B.R., and Murray C.J.L. Science 257 (1992) 1055
2. Barnes P.F., Blotch A.B., Davidson P.T., and Snider D.E. N. Engl. J. Med. 324 (1991) 1644
3. Sbarbaro J.A. Chest 111 (1997) 1149
4. Mandell G.L., and Sande M.A. In: Gilman A.G., Goodman L.S., Rall T.W., Vies A.S., and Taylor P. (Eds). The Pharmacological Bass of Therapeutics. 8th ed. (1990), Pergamon press, NewYork 1146
5. Fujiwara P.I., Cook S.V., Rutherford C.M., Crawford J.T., Glickman S.E., Kreiswirth B.N., Sachdev P.S., Osahan S.S., Ebrahimzadeh A., and Frieden T.R. Arch. Intern. Med. 157 (1997) 531
6. Schaberg T., Gloger G., Reichert B., Mauch H., and Lode H. Pneumologie 50 (1996) 21
7. Blair I.A., Timoco R.M., Brodie M.J., Clarc R.A., Dollery T., Timbrell J.A., and Beever I.A. Hum. Toxicol. 4 (1985) 195
8. Kucukguzel S.G., and Rollas S. Farmaco 57 (2002) 583
9. Shenoy G.G., Bhat A.R., Bhat G.V., and Kotian M. Ind. J. Het. Chem. 10 (2001) 197
10. Heifets L.B., Flory M.A., and Lindholm-Levy P.J. Antimicrob. Agents Chemother. 33 (1989) 1252
11. Gundersen L.L., Nissen-Meyer J., and Spilsberg B. J. Med. Chem. 45 (2002) 1383