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Volumn 46, Issue 5, 2011, Pages 1942-1948
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Synthesis of some novel benzofuran-2-yl(4,5-dihyro-3,5-substituted diphenylpyrazol-1-yl) methanones and studies on the antiproliferative effects and reversal of multidrug resistance of human MDR1-gene transfected mouse lymphoma cells in vitro
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Author keywords
Antiproliferative activity; Benzofuran bearing pyrazolines; MDR reversal activity; Microwave irradiation; Mouse lymphoma cells
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Indexed keywords
(BENZOFURAN 2 YL)(4,5 DIHYDRO 3 PHENYL 5 4 TOLYLPYRAZOL 1 YL)METHANONE;
(BENZOFURAN 2 YL)(4,5 DIHYDRO 3,5 DIPHENYLPYRAZOL 1 YL)METHANONE;
(BENZOFURAN 2 YL)[3 (4 CHLOROPHENYL) 4,5 DIHYDRO 5 (3,4 DIMETHOXYPHENYL)PYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 CHLOROPHENYL) 4,5 DIHYDRO 5 (4 METHOXYPHENYL)PYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 CHLOROPHENYL) 4,5 DIHYDRO 5 (4 NITROPHENYL)PYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 CHLOROPHENYL) 4,5 DIHYDRO 5 4 TOLYLPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 CHLOROPHENYL) 4,5 DIHYDRO 5 PHENYLPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 CHLOROPHENYL) 5 (4 FLUOROPHENYL) 4,5 DIHYDROPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 FLUOROPHENYL) 4,5 DIHYDRO 5 (3,4 DIMETHOXYPHENYL)PYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 FLUOROPHENYL) 4,5 DIHYDRO 5 (4 METHOXYPHENYL)PYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 FLUOROPHENYL) 4,5 DIHYDRO 5 (4 NITROPHENYL)PYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 FLUOROPHENYL) 4,5 DIHYDRO 5 4 TOLYLPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[3 (4 FLUOROPHENYL) 4,5 DIHYDRO 5 PHENYLPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[4,5 DIHYDRO 5 (3,4 DIMETHOXYPHENYL) 3 PHENYLPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[4,5 DIHYDRO 5 (4 METHOXYPHENYL) 3 PHENYLPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[4,5 DIHYDRO 5 (4 NITROPHENYL) 3 PHENYLPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[5 (2 CHLOROPHENYL) 3 (4 CHLOROPHENYL) 4,5 DIHYDROPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[5 (2 CHLOROPHENYL) 3 (4 FLUOROPHENYL) 4,5 DIHYDROPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[5 (2 CHLOROPHENYL) 4,5 DIHYDRO 3 PHENYLPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[5 (4 CHLOROPHENYL) 3 (4 FLUOROPHENYL) 4,5 DIHYDROPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[5 (4 CHLOROPHENYL) 4,5 DIHYDRO 3 PHENYLPYRAZOL 1 YL]METHANONE;
(BENZOFURAN 2 YL)[5 (4 FLUOROPHENYL) 4,5 DIHYDRO 3 PHENYLPYRAZOL 1 YL]METHANONE;
[3,5 BIS(4 CHLOROPHENYL) 4,5 DIHYDROPYRAZOL 1 YL](BENZOFURAN 2 YL)METHANONE;
[3,5 BIS(4 FLUOROPHENYL) 4,5 DIHYDROPYRAZOL 1 YL](BENZOFURAN 2 YL)METHANONE;
ANTINEOPLASTIC AGENT;
BENZOFURAN DERIVATIVE;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
DRUG SYNTHESIS;
IN VITRO STUDY;
LYMPHOMA CELL;
MICROWAVE IRRADIATION;
MOUSE;
MULTIDRUG RESISTANCE;
NONHUMAN;
ANIMALS;
ANTINEOPLASTIC AGENTS;
BENZOFURANS;
CELL LINE, TUMOR;
CELL PROLIFERATION;
DRUG RESISTANCE, MULTIPLE;
DRUG RESISTANCE, NEOPLASM;
DRUG SCREENING ASSAYS, ANTITUMOR;
HUMANS;
LYMPHOMA, T-CELL;
METHANE;
MICE;
MOLECULAR STRUCTURE;
P-GLYCOPROTEIN;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
STEREOISOMERISM;
STRUCTURE-ACTIVITY RELATIONSHIP;
TRANSFECTION;
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EID: 79953212556
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2011.02.045 Document Type: Article |
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Times cited : (62)
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References (28)
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