Diaryl hydrazones as multifunctional inhibitors of amyloid self-assembly

Biochemistry

Volumn 52, Issue 7, 2013, Pages 1137-1148

  Török, Béla ^a   Sood, Abha ^a   Bag, Seema ^a   Tulsan, Rekha ^a   Ghosh, Sanjukta ^a   Borkin, Dmitry ^a   Kennedy, Arleen R ^a   Melanson, Michelle ^a   Madden, Richard ^a   Zhou, Weihong ^a   Levine, Harry ^b   Török, Marianna ^a  

^a UNIVERSITY OF MASSACHUSETTS BOSTON   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; ASCORBIC ACID; ATOMIC FORCE MICROSCOPY; COLORIMETRY; GLYCOPROTEINS; OLIGOMERS; RESVERATROL; SCAFFOLDS;

2 ,2-DIPHENYL-1-PICRYLHYDRAZYL; ANTIOXIDANT PROPERTIES; DESIGN AND APPLICATION; MULTIFUNCTIONAL INHIBITORS; OLIGOMER FORMATIONS; RADICAL SCAVENGING EFFECT; SMALL MOLECULE INHIBITOR; STRUCTURE ACTIVITY RELATIONSHIPS;

SELF ASSEMBLY;

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; ANTIOXIDANT; AROMATIC COMPOUND; ASCORBIC ACID; BENZALDEHYDE DERIVATIVE; DIARYL HYDRAZONE DERIVATIVE; HYDRAZONE DERIVATIVE; NOOTROPIC AGENT; OLIGOMER; PHENYLHYDRAZINE DERIVATIVE; PROTEIN INHIBITOR; RESVERATROL; SUPEROXIDE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; COLORIMETRY; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; FLUOROMETRY; GEL PERMEATION CHROMATOGRAPHY; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN POLYMERIZATION; PROTEIN SYNTHESIS INHIBITION; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

EID: 84874102955     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3012059     Document Type: Article

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