-
1
-
-
0030908095
-
Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins
-
Harper J.D., and Lansbury Jr. P.T. Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins. Annu. Rev. Biochem. 66 (1997) 385-407
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 385-407
-
-
Harper, J.D.1
Lansbury Jr., P.T.2
-
2
-
-
0028180518
-
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease
-
Hensley K., Carney J.M., Mattson M.P., Aksenova M., Harris M., Wu J.F., Floyd R.A., and Butterfield D.A. A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 3270-3274
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 3270-3274
-
-
Hensley, K.1
Carney, J.M.2
Mattson, M.P.3
Aksenova, M.4
Harris, M.5
Wu, J.F.6
Floyd, R.A.7
Butterfield, D.A.8
-
3
-
-
0035753031
-
Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases
-
Tabner B.J., Turnbull S., El Agnaf O., and Allsop D. Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. Curr. Top. Med. Chem. 1 (2001) 507-517
-
(2001)
Curr. Top. Med. Chem.
, vol.1
, pp. 507-517
-
-
Tabner, B.J.1
Turnbull, S.2
El Agnaf, O.3
Allsop, D.4
-
4
-
-
0026730350
-
Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation
-
Dyrks T., Dyrks E., Hartmann T., Masters C., and Beyreuther K. Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation. J. Biol. Chem. 267 (1992) 18210-18217
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 18210-18217
-
-
Dyrks, T.1
Dyrks, E.2
Hartmann, T.3
Masters, C.4
Beyreuther, K.5
-
5
-
-
12844260763
-
Methionine oxidation by reactive oxygen species: reaction mechanisms and relevance to Alzheimer's disease
-
Schoneich C. Methionine oxidation by reactive oxygen species: reaction mechanisms and relevance to Alzheimer's disease. Biochim. Biophys. Acta 1703 (2005) 111-119
-
(2005)
Biochim. Biophys. Acta
, vol.1703
, pp. 111-119
-
-
Schoneich, C.1
-
6
-
-
33947708348
-
The molecular mechanisms of the anti-amyloid effects of phenols
-
Shoval H., Lichtenberg D., and Gazit E. The molecular mechanisms of the anti-amyloid effects of phenols. Amyloid. 14 (2007) 73-87
-
(2007)
Amyloid.
, vol.14
, pp. 73-87
-
-
Shoval, H.1
Lichtenberg, D.2
Gazit, E.3
-
7
-
-
33747861696
-
Involvement of oxidative stress in Alzheimer disease
-
Nunomura A., Castellani R.J., Zhu X., Moreira P.I., Perry G., and Smith M.A. Involvement of oxidative stress in Alzheimer disease. J. Neuropathol. Exp. Neurol. 65 (2006) 631-641
-
(2006)
J. Neuropathol. Exp. Neurol.
, vol.65
, pp. 631-641
-
-
Nunomura, A.1
Castellani, R.J.2
Zhu, X.3
Moreira, P.I.4
Perry, G.5
Smith, M.A.6
-
8
-
-
35948936850
-
Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron
-
Nakamura M., Shishido N., Nunomura A., Smith M.A., Perry G., Hayashi Y., Nakayama K., and Hayashi T. Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron. Biochemistry 46 (2007) 12737-12743
-
(2007)
Biochemistry
, vol.46
, pp. 12737-12743
-
-
Nakamura, M.1
Shishido, N.2
Nunomura, A.3
Smith, M.A.4
Perry, G.5
Hayashi, Y.6
Nakayama, K.7
Hayashi, T.8
-
9
-
-
0035500510
-
Amyloid-beta: an antioxidant that becomes a pro-oxidant and critically contributes to Alzheimer's disease
-
Kontush A. Amyloid-beta: an antioxidant that becomes a pro-oxidant and critically contributes to Alzheimer's disease. Free Radic. Biol. Med. 31 (2001) 1120-1131
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 1120-1131
-
-
Kontush, A.1
-
11
-
-
27544511750
-
Formation and stabilization model of the 42-mer Abeta radical: implications for the long-lasting oxidative stress in Alzheimer's disease
-
Murakami K., Irie K., Ohigashi H., Hara H., Nagao M., Shimizu T., and Shirasawa T. Formation and stabilization model of the 42-mer Abeta radical: implications for the long-lasting oxidative stress in Alzheimer's disease. J. Am. Chem. Soc. 127 (2005) 15168-15174
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 15168-15174
-
-
Murakami, K.1
Irie, K.2
Ohigashi, H.3
Hara, H.4
Nagao, M.5
Shimizu, T.6
Shirasawa, T.7
-
12
-
-
1842519391
-
Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide
-
Butterfield D.A., and Bush A.I. Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide. Neurobiol. Aging 25 (2004) 563-568
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 563-568
-
-
Butterfield, D.A.1
Bush, A.I.2
-
13
-
-
33645929400
-
Inhibition of amyloid fibril formation and cytotoxicity by hydroxyindole derivatives
-
Cohen T., Frydman-Marom A., Rechter M., and Gazit E. Inhibition of amyloid fibril formation and cytotoxicity by hydroxyindole derivatives. Biochemistry 45 (2006) 4727-4735
-
(2006)
Biochemistry
, vol.45
, pp. 4727-4735
-
-
Cohen, T.1
Frydman-Marom, A.2
Rechter, M.3
Gazit, E.4
-
14
-
-
33749830133
-
Molecular mapping of the recognition interface between the islet amyloid polypeptide and insulin
-
Gilead S., Wolfenson H., and Gazit E. Molecular mapping of the recognition interface between the islet amyloid polypeptide and insulin. Angew. Chem. Int. Ed Engl. 45 (2006) 6476-6480
-
(2006)
Angew. Chem. Int. Ed Engl.
, vol.45
, pp. 6476-6480
-
-
Gilead, S.1
Wolfenson, H.2
Gazit, E.3
-
15
-
-
0029863551
-
Inhibition of amyloid beta protein aggregation and neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger
-
Tomiyama T., Shoji A., Kataoka K., Suwa Y., Asano S., Kaneko H., and Endo N. Inhibition of amyloid beta protein aggregation and neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger. J. Biol. Chem. 271 (1996) 6839-6844
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6839-6844
-
-
Tomiyama, T.1
Shoji, A.2
Kataoka, K.3
Suwa, Y.4
Asano, S.5
Kaneko, H.6
Endo, N.7
-
16
-
-
0023505008
-
Spin trapping: ESR parameters of spin adducts
-
Buettner G.R. Spin trapping: ESR parameters of spin adducts. Free Radic. Biol. Med. 3 (1987) 259-303
-
(1987)
Free Radic. Biol. Med.
, vol.3
, pp. 259-303
-
-
Buettner, G.R.1
-
17
-
-
0028873243
-
Hydroxyl radical generation by coal mine dust: possible implication to coal workers' pneumoconiosis (CWP)
-
Dalal N.S., Newman J., Pack D., Leonard S., and Vallyathan V. Hydroxyl radical generation by coal mine dust: possible implication to coal workers' pneumoconiosis (CWP). Free Radic. Biol. Med. 18 (1995) 11-20
-
(1995)
Free Radic. Biol. Med.
, vol.18
, pp. 11-20
-
-
Dalal, N.S.1
Newman, J.2
Pack, D.3
Leonard, S.4
Vallyathan, V.5
-
18
-
-
12144282992
-
Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides
-
Huang X., Atwood C.S., Moir R.D., Hartshorn M.A., Tanzi R.E., and Bush A.I. Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides. J. Biol. Inorg. Chem. 9 (2004) 954-960
-
(2004)
J. Biol. Inorg. Chem.
, vol.9
, pp. 954-960
-
-
Huang, X.1
Atwood, C.S.2
Moir, R.D.3
Hartshorn, M.A.4
Tanzi, R.E.5
Bush, A.I.6
-
19
-
-
27744542593
-
Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia
-
Tabner B.J., El Agnaf O.M., Turnbull S., German M.J., Paleologou K.E., Hayashi Y., Cooper L.J., Fullwood N.J., and Allsop D. Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia. J. Biol. Chem. 280 (2005) 35789-35792
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35789-35792
-
-
Tabner, B.J.1
El Agnaf, O.M.2
Turnbull, S.3
German, M.J.4
Paleologou, K.E.5
Hayashi, Y.6
Cooper, L.J.7
Fullwood, N.J.8
Allsop, D.9
-
20
-
-
1542364225
-
Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro
-
Ono K., Hasegawa K., Naiki H., and Yamada M. Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. J. Neurosci. Res. 75 (2004) 742-750
-
(2004)
J. Neurosci. Res.
, vol.75
, pp. 742-750
-
-
Ono, K.1
Hasegawa, K.2
Naiki, H.3
Yamada, M.4
-
21
-
-
33644945380
-
Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro
-
Ono K., and Yamada M. Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro. J. Neurochem. 97 (2006) 105-115
-
(2006)
J. Neurochem.
, vol.97
, pp. 105-115
-
-
Ono, K.1
Yamada, M.2
-
22
-
-
0141642253
-
Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease
-
Ono K., Yoshiike Y., Takashima A., Hasegawa K., Naiki H., and Yamada M. Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease. J. Neurochem. 87 (2003) 172-181
-
(2003)
J. Neurochem.
, vol.87
, pp. 172-181
-
-
Ono, K.1
Yoshiike, Y.2
Takashima, A.3
Hasegawa, K.4
Naiki, H.5
Yamada, M.6
-
23
-
-
7044286419
-
Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro
-
Ono K., Hasegawa K., Naiki H., and Yamada M. Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro. Biochim. Biophys. Acta 1690 (2004) 193-202
-
(2004)
Biochim. Biophys. Acta
, vol.1690
, pp. 193-202
-
-
Ono, K.1
Hasegawa, K.2
Naiki, H.3
Yamada, M.4
-
24
-
-
0031870516
-
Lipid oxidation in unfractionated serum and plasma
-
Schnitzer E., Pinchuk I., Bor A., Fainaru M., Samuni A.M., and Lichtenberg D. Lipid oxidation in unfractionated serum and plasma. Chem. Phys. Lipids 92 (1998) 151-170
-
(1998)
Chem. Phys. Lipids
, vol.92
, pp. 151-170
-
-
Schnitzer, E.1
Pinchuk, I.2
Bor, A.3
Fainaru, M.4
Samuni, A.M.5
Lichtenberg, D.6
-
25
-
-
3342991494
-
Experimental investigation of protein folding and misfolding
-
Dobson C.M. Experimental investigation of protein folding and misfolding. Methods 34 (2004) 4-14
-
(2004)
Methods
, vol.34
, pp. 4-14
-
-
Dobson, C.M.1
-
26
-
-
34447251553
-
Copper-mediated formation of hydrogen peroxide from the amylin peptide: a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?
-
Masad A., Hayes L., Tabner B.J., Turnbull S., Cooper L.J., Fullwood N.J., German M.J., Kametani F., El Agnaf O.M., and Allsop D. Copper-mediated formation of hydrogen peroxide from the amylin peptide: a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?. FEBS Lett. 581 (2007) 3489-3493
-
(2007)
FEBS Lett.
, vol.581
, pp. 3489-3493
-
-
Masad, A.1
Hayes, L.2
Tabner, B.J.3
Turnbull, S.4
Cooper, L.J.5
Fullwood, N.J.6
German, M.J.7
Kametani, F.8
El Agnaf, O.M.9
Allsop, D.10
-
27
-
-
12844266117
-
The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity
-
Butterfield D.A., and Boyd-Kimball D. The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity. Biochim. Biophys. Acta 1703 (2005) 149-156
-
(2005)
Biochim. Biophys. Acta
, vol.1703
, pp. 149-156
-
-
Butterfield, D.A.1
Boyd-Kimball, D.2
-
28
-
-
0034527983
-
Metal chelation as a potential therapy for Alzheimer's disease
-
Cuajungco M.P., Faget K.Y., Huang X., Tanzi R.E., and Bush A.I. Metal chelation as a potential therapy for Alzheimer's disease. Ann. N. Y. Acad. Sci. 920 (2000) 292-304
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.920
, pp. 292-304
-
-
Cuajungco, M.P.1
Faget, K.Y.2
Huang, X.3
Tanzi, R.E.4
Bush, A.I.5
-
29
-
-
44449144587
-
Phenolsulfonphthalein, but not phenolphthalein, inhibits amyloid fibril formation: implications for the modulation of amyloid self-assembly
-
Levy M., Porat Y., Bacharach E., Shalev D.E., and Gazit E. Phenolsulfonphthalein, but not phenolphthalein, inhibits amyloid fibril formation: implications for the modulation of amyloid self-assembly. Biochemistry 47 (2008) 5896-5904
-
(2008)
Biochemistry
, vol.47
, pp. 5896-5904
-
-
Levy, M.1
Porat, Y.2
Bacharach, E.3
Shalev, D.E.4
Gazit, E.5
-
30
-
-
4644275696
-
Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models
-
Baum L., and Ng A. Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models. J. Alzheimers Dis. 6 (2004) 367-377
-
(2004)
J. Alzheimers Dis.
, vol.6
, pp. 367-377
-
-
Baum, L.1
Ng, A.2
-
31
-
-
0033844944
-
Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42
-
Atwood C.S., Scarpa R.C., Huang X., Moir R.D., Jones W.D., Fairlie D.P., Tanzi R.E., and Bush A.I. Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42. J. Neurochem. 75 (2000) 1219-1233
-
(2000)
J. Neurochem.
, vol.75
, pp. 1219-1233
-
-
Atwood, C.S.1
Scarpa, R.C.2
Huang, X.3
Moir, R.D.4
Jones, W.D.5
Fairlie, D.P.6
Tanzi, R.E.7
Bush, A.I.8
-
32
-
-
14944372848
-
NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models
-
Cole G.M., Morihara T., Lim G.P., Yang F., Begum A., and Frautschy S.A. NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models. Ann. N. Y. Acad. Sci. 1035 (2004) 68-84
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1035
, pp. 68-84
-
-
Cole, G.M.1
Morihara, T.2
Lim, G.P.3
Yang, F.4
Begum, A.5
Frautschy, S.A.6
-
33
-
-
28844488778
-
Redox properties of tea polyphenols and related biological activities
-
Sang S., Hou Z., Lambert J.D., and Yang C.S. Redox properties of tea polyphenols and related biological activities. Antioxid. Redox. Signal. 7 (2005) 1704-1714
-
(2005)
Antioxid. Redox. Signal.
, vol.7
, pp. 1704-1714
-
-
Sang, S.1
Hou, Z.2
Lambert, J.D.3
Yang, C.S.4
-
34
-
-
0028233551
-
Oxygen radicals generation and DNA scission by anticancer and synthetic quinones
-
Weiner L.M. Oxygen radicals generation and DNA scission by anticancer and synthetic quinones. Methods Enzymol. 233 (1994) 92-105
-
(1994)
Methods Enzymol.
, vol.233
, pp. 92-105
-
-
Weiner, L.M.1
-
35
-
-
18344414746
-
The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
Huang X., Atwood C.S., Hartshorn M.A., Multhaup G., Goldstein L.E., Scarpa R.C., Cuajungco M.P., Gray D.N., Lim J., Moir R.D., Tanzi R.E., and Bush A.I. The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 38 (1999) 7609-7616
-
(1999)
Biochemistry
, vol.38
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
Multhaup, G.4
Goldstein, L.E.5
Scarpa, R.C.6
Cuajungco, M.P.7
Gray, D.N.8
Lim, J.9
Moir, R.D.10
Tanzi, R.E.11
Bush, A.I.12
-
36
-
-
0035827681
-
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits
-
Curtain C.C., Ali F., Volitakis I., Cherny R.A., Norton R.S., Beyreuther K., Barrow C.J., Masters C.L., Bush A.I., and Barnham K.J. Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits. J. Biol. Chem. 276 (2001) 20466-20473
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20466-20473
-
-
Curtain, C.C.1
Ali, F.2
Volitakis, I.3
Cherny, R.A.4
Norton, R.S.5
Beyreuther, K.6
Barrow, C.J.7
Masters, C.L.8
Bush, A.I.9
Barnham, K.J.10
-
37
-
-
34547414064
-
Redox chemistry of copper-amyloid-beta: the generation of hydroxyl radical in the presence of ascorbate is linked to redox-potentials and aggregation state
-
Guilloreau L., Combalbert S., Sournia-Saquet A., Mazarguil H., and Faller P. Redox chemistry of copper-amyloid-beta: the generation of hydroxyl radical in the presence of ascorbate is linked to redox-potentials and aggregation state. ChemBioChem. 8 (2007) 1317-1325
-
(2007)
ChemBioChem.
, vol.8
, pp. 1317-1325
-
-
Guilloreau, L.1
Combalbert, S.2
Sournia-Saquet, A.3
Mazarguil, H.4
Faller, P.5
-
38
-
-
42049116923
-
Alzheimer disease and the role of free radicals in the pathogenesis of the disease
-
Moreira P.I., Santos M.S., Oliveira C.R., Shenk J.C., Nunomura A., Smith M.A., Zhu X., and Perry G. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS. Neurol. Disord. Drug Targets. 7 (2008) 3-10
-
(2008)
CNS. Neurol. Disord. Drug Targets.
, vol.7
, pp. 3-10
-
-
Moreira, P.I.1
Santos, M.S.2
Oliveira, C.R.3
Shenk, J.C.4
Nunomura, A.5
Smith, M.A.6
Zhu, X.7
Perry, G.8
-
39
-
-
0033559462
-
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
-
Nunomura A., Perry G., Pappolla M.A., Wade R., Hirai K., Chiba S., and Smith M.A. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J. Neurosci. 19 (1999) 1959-1964
-
(1999)
J. Neurosci.
, vol.19
, pp. 1959-1964
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Wade, R.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
40
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
-
Lim G.P., Chu T., Yang F., Beech W., Frautschy S.A., and Cole G.M. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. 21 (2001) 8370-8377
-
(2001)
J. Neurosci.
, vol.21
, pp. 8370-8377
-
-
Lim, G.P.1
Chu, T.2
Yang, F.3
Beech, W.4
Frautschy, S.A.5
Cole, G.M.6
|