Disassembly of preformed amyloid beta fibrils by small organofluorine molecules

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 7, 2011, Pages 2044-2047

  Sood, Abha ^a   Abid, Mohammed ^a,b   Sauer, Catharine ^a   Hailemichael, Samson ^a   Foster, Michelle ^a   Török, Béla ^a   Török, Marianna ^a  

^a UNIVERSITY OF MASSACHUSETTS BOSTON   (United States)

^b GEORGIA SOUTHERN UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Amyloid beta; Disassembly; Fibrils; Organofluorine compounds

Indexed keywords

5' HALOGEN SUBSTITUTED 3,3,3 TRIFLUOROMETHYL 2 HYDROXY (INDOL 3 YL) PROPIONIC ACID ESTER DERIVATIVE; AMYLOID BETA PROTEIN INHIBITOR; CHLORO DERIVATIVE; MELATONIN; ORGANOFLUORINE DERIVATIVE; PROTEIN INHIBITOR; THIOFLAVINE; UNCLASSIFIED DRUG;

ARTICLE; ATOMIC FORCE MICROSCOPY; CHIRALITY; CHROMATIN ASSEMBLY AND DISASSEMBLY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; FIBER; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; INFRARED SPECTROSCOPY;

AMYLOID BETA-PEPTIDES; FLUORESCENCE; FLUORINE; MICROSCOPY, ATOMIC FORCE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 79952487581     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.02.012     Document Type: Article

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