Flexible backbone sampling methods to model and design protein alternative conformations

Methods in Enzymology

Volumn 523, Issue , 2013, Pages 61-85

  Ollikainen, Noah ^a   Smith, Colin A ^a,d   Fraser, James S ^b,c   Kortemme, Tanja ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Alternative conformations; Backrub; Conformational heterogeneity; Conformational sampling; Protein design; Protein dynamics; Ringer; Rosetta

Indexed keywords

CYCLOPHILIN A; PDZ PROTEIN; RECEPTOR PROTEIN; TRIOSEPHOSPHATE ISOMERASE;

ARTICLE; CATALYSIS; CHEMICAL ENVIRONMENT; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR DYNAMICS; MONTE CARLO METHOD; NUCLEAR MAGNETIC RESONANCE; PHAGE DISPLAY; POINT MUTATION; POSITION WEIGHT MATRIX; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN SECONDARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; ROOM TEMPERATURE; SAMPLING; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

EID: 84874036318     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-394292-0.00004-7     Document Type: Chapter

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