Structure-based prediction of the peptide sequence space recognized by natural and synthetic PDZ domains

Journal of Molecular Biology

Volumn 402, Issue 2, 2010, Pages 460-474

  Smith, Colin A ^a   Kortemme, Tanja ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Backrub backbone flexibility; PDZ domain; Protein design; Specificity prediction; Tolerated sequence space

Indexed keywords

AMINO ACID DERIVATIVE; PEPTIDE; PROTEIN BINDING;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE; PDZ DOMAIN; PHAGE DISPLAY; POINT MUTATION; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN PROTEIN INTERACTION; WILD TYPE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; PROCEDURES; PROTEIN TERTIARY STRUCTURE;

COMPUTATIONAL BIOLOGY; MODELS, MOLECULAR; PDZ DOMAINS; PEPTIDES; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

EID: 77956730468     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.07.032     Document Type: Article

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