Accessing protein conformational ensembles using room-temperature X-ray crystallography

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 39, 2011, Pages 16247-16252

  Fraser, James S ^a,c   Van Den Bedem, Henry ^b   Samelson, Avi J ^a   Lang, P Therese ^a   Holton, James M ^c,d   Echols, Nathaniel ^d   Alber, Tom ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Energy landscape; Protein conformational dynamics; qFit; Ringer

Indexed keywords

H RAS PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CHEMICAL STRUCTURE; COOLING; CRYSTAL STRUCTURE; ELECTRON; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN STRUCTURE; ROOM TEMPERATURE; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEINS; SOLVENTS;

EID: 80053626537     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1111325108     Document Type: Article

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