메뉴 건너뛰기




Volumn 18, Issue 39, 2012, Pages 5533-5541

Experimental and clinical evidence of antioxidant therapy in acute pancreatitis

Author keywords

Acute pancreatitis; Antioxidants; Clinical; Experimental; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; CAFFEIC ACID PHENETHYL ESTER; CARNITINE; CYTOKINE; EBSELEN; HYDROXYETHYLMETHYLCELLULOSE; LIPOXYGENASE; MELATONIN; PLACEBO; PROTEIN KINASE C; QUERCETIN; RESVERATROL; RETINOL; SCAVENGER; SELENIUM; TRANSCRIPTION FACTOR;

EID: 84873897103     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v18.i39.5533     Document Type: Review
Times cited : (45)

References (118)
  • 1
    • 33644787377 scopus 로고    scopus 로고
    • Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats
    • Eşrefoǧlu M, Gül M, Ates B, Batçioǧlu K, Selimoǧlu MA. Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats. World J Gastroenterol 2006; 12: 259-264
    • (2006) World J Gastroenterol , vol.12 , pp. 259-264
    • Eşrefoǧlu, M.1    Gül, M.2    Ates, B.3    Batçioǧlu, K.4    Selimoǧlu, M.A.5
  • 2
    • 71049141307 scopus 로고    scopus 로고
    • Liver lipid peroxidation and antioxidant capacity in cerulein-induced acute pancreatitis
    • Batcioglu K, Gul M, Uyumlu AB, Esrefoglu M. Liver lipid peroxidation and antioxidant capacity in cerulein-induced acute pancreatitis. Braz J Med Biol Res 2009; 42: 776-782
    • (2009) Braz J Med Biol Res , vol.42 , pp. 776-782
    • Batcioglu, K.1    Gul, M.2    Uyumlu, A.B.3    Esrefoglu, M.4
  • 3
    • 41949089723 scopus 로고    scopus 로고
    • Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis
    • Eşrefoǧlu M, Gül M, Turan F. Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis. Dig Dis Sci 2008; 53: 1303-1310
    • (2008) Dig Dis Sci , vol.53 , pp. 1303-1310
    • Eşrefoǧlu, M.1    Gül, M.2    Turan, F.3
  • 4
    • 59449095049 scopus 로고    scopus 로고
    • The beneficial effects of pentoxifylline on caerulein-induced acute pancreatitis in rats
    • Gül M, Eşrefoǧlu M, Oztürk F, Ateş B, Otlu A. The beneficial effects of pentoxifylline on caerulein-induced acute pancreatitis in rats. Dig Dis Sci 2009; 54: 555-563
    • (2009) Dig Dis Sci , vol.54 , pp. 555-563
    • Gül, M.1    Eşrefoǧlu, M.2    Oztürk, F.3    Ateş, B.4    Otlu, A.5
  • 7
    • 80054031724 scopus 로고    scopus 로고
    • Antioxidant therapy in acute pancreatitis: Experimental and clinical evidence
    • Hackert T, Werner J. Antioxidant therapy in acute pancreatitis: experimental and clinical evidence. Antioxid Redox Signal 2011; 15: 2767-2777
    • (2011) Antioxid Redox Signal , vol.15 , pp. 2767-2777
    • Hackert, T.1    Werner, J.2
  • 8
    • 0029111530 scopus 로고
    • Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide
    • Inoue S, Kawanishi S. Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide. FEBS Lett 1995; 371: 86-88
    • (1995) FEBS Lett , vol.371 , pp. 86-88
    • Inoue, S.1    Kawanishi, S.2
  • 9
    • 1642422773 scopus 로고    scopus 로고
    • Mitochondrial free radical production and cell signaling
    • Cadenas E. Mitochondrial free radical production and cell signaling. Mol Aspects Med 2004; 25: 17-26
    • (2004) Mol Aspects Med , vol.25 , pp. 17-26
    • Cadenas, E.1
  • 10
    • 0036139856 scopus 로고    scopus 로고
    • The mitochondrial production of reactive oxygen species: Mechanisms and implications in human pathology
    • Lenaz G. The mitochondrial production of reactive oxygen species: mechanisms and implications in human pathology. IUBMB Life 2001; 52: 159-164
    • (2001) IUBMB Life , vol.52 , pp. 159-164
    • Lenaz, G.1
  • 11
    • 29944438881 scopus 로고    scopus 로고
    • Necrotic death as a cell fate
    • Zong WX, Thompson CB. Necrotic death as a cell fate. Genes Dev 2006; 20: 1-15
    • (2006) Genes Dev , vol.20 , pp. 1-15
    • Zong, W.X.1    Thompson, C.B.2
  • 12
    • 0001341681 scopus 로고
    • Cell injury and death
    • In: McGee JOD, Isaacson PG, Wright N. Oxford: Oxford University Press
    • Wyllie AH, Duvall E. Cell injury and death. In: McGee JOD, Isaacson PG, Wright N. Oxford Text book of Pathology. Oxford: Oxford University Press, 1992: 142-156
    • (1992) Oxford Text book of Pathology , pp. 142-156
    • Wyllie, A.H.1    Duvall, E.2
  • 15
    • 0037160091 scopus 로고    scopus 로고
    • Topology of superoxide production from different sites in the mitochondrial electron transport chain
    • St-Pierre J, Buckingham JA, Roebuck SJ, Brand MD. Topology of superoxide production from different sites in the mitochondrial electron transport chain. J Biol Chem 2002; 277: 44784-44790
    • (2002) J Biol Chem , vol.277 , pp. 44784-44790
    • St-Pierre, J.1    Buckingham, J.A.2    Roebuck, S.J.3    Brand, M.D.4
  • 16
    • 0037007227 scopus 로고    scopus 로고
    • Mitochondria are morphologically and functionally heterogeneous within cells
    • Collins TJ, Berridge MJ, Lipp P, Bootman MD. Mitochondria are morphologically and functionally heterogeneous within cells. EMBO J 2002; 21: 1616-1627
    • (2002) EMBO J , vol.21 , pp. 1616-1627
    • Collins, T.J.1    Berridge, M.J.2    Lipp, P.3    Bootman, M.D.4
  • 17
    • 0035702819 scopus 로고    scopus 로고
    • New control of mitochondrial membrane potential and ROS formation--a hypothesis
    • Lee I, Bender E, Arnold S, Kadenbach B. New control of mitochondrial membrane potential and ROS formation--a hypothesis. Biol Chem 2001; 382: 1629-1636
    • (2001) Biol Chem , vol.382 , pp. 1629-1636
    • Lee, I.1    Bender, E.2    Arnold, S.3    Kadenbach, B.4
  • 18
    • 11144338185 scopus 로고    scopus 로고
    • Redox active calcium ion channels and cell death
    • Waring P. Redox active calcium ion channels and cell death. Arch Biochem Biophys 2005; 434: 33-42
    • (2005) Arch Biochem Biophys , vol.434 , pp. 33-42
    • Waring, P.1
  • 19
    • 0026032580 scopus 로고
    • Mechanisms of oxidant injury of cells
    • Cochrane CG. Mechanisms of oxidant injury of cells. Mol Aspects Med 1991; 12: 137-147
    • (1991) Mol Aspects Med , vol.12 , pp. 137-147
    • Cochrane, C.G.1
  • 21
    • 0031172139 scopus 로고    scopus 로고
    • Potent protective effect of melatonin on chromium(VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes
    • Susa N, Ueno S, Furukawa Y, Ueda J, Sugiyama M. Potent protective effect of melatonin on chromium(VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes. Toxicol Appl Pharmacol 1997; 144: 377-384
    • (1997) Toxicol Appl Pharmacol , vol.144 , pp. 377-384
    • Susa, N.1    Ueno, S.2    Furukawa, Y.3    Ueda, J.4    Sugiyama, M.5
  • 22
    • 0029100890 scopus 로고
    • Poly(adenosine diphosphate ribose) polymerase inhibition prevents necrosis induced by H2O2 but not apoptosis
    • Watson AJ, Askew JN, Benson RS. Poly(adenosine diphosphate ribose) polymerase inhibition prevents necrosis induced by H2O2 but not apoptosis. Gastroenterology 1995; 109: 472-482
    • (1995) Gastroenterology , vol.109 , pp. 472-482
    • Watson, A.J.1    Askew, J.N.2    Benson, R.S.3
  • 23
    • 0024841207 scopus 로고
    • Tell me about free radicals, doctor: A review
    • Halliwell B. Tell me about free radicals, doctor: a review. J R Soc Med 1989; 82: 747-752
    • (1989) J R Soc Med , vol.82 , pp. 747-752
    • Halliwell, B.1
  • 24
    • 76749144736 scopus 로고    scopus 로고
    • Cell Injury and Death: Oxidative Stress and Antioxidant Defense System: Review
    • Esrefoglu M. Cell Injury and Death: Oxidative Stress and Antioxidant Defense System: Review. Turkiye Klinikleri J Med Sci 2009; 29: 1660-1676
    • (2009) Turkiye Klinikleri J Med Sci , vol.29 , pp. 1660-1676
    • Esrefoglu, M.1
  • 25
    • 0021170386 scopus 로고
    • Oxygen metabolites stimulate thromboxane production and vasoconstriction in isolated saline-perfused rabbit lungs
    • Tate RM, Morris HG, Schroeder WR, Repine JE. Oxygen metabolites stimulate thromboxane production and vasoconstriction in isolated saline-perfused rabbit lungs. J Clin Invest 1984; 74: 608-613
    • (1984) J Clin Invest , vol.74 , pp. 608-613
    • Tate, R.M.1    Morris, H.G.2    Schroeder, W.R.3    Repine, J.E.4
  • 26
    • 0031057619 scopus 로고    scopus 로고
    • Free radical enhancement promotes leucocyte recruitment through a PAF and LTB4 dependent mechanism
    • Hotter G, Closa D, Prats N, Pi F, Gelpí E, Roselló-Catafau J. Free radical enhancement promotes leucocyte recruitment through a PAF and LTB4 dependent mechanism. Free Radic Biol Med 1997; 22: 947-954
    • (1997) Free Radic Biol Med , vol.22 , pp. 947-954
    • Hotter, G.1    Closa, D.2    Prats, N.3    Pi, F.4    Gelpí, E.5    Roselló-Catafau, J.6
  • 27
    • 0021220058 scopus 로고
    • The role of oxygen-derived free radicals in the pathogenesis of acute pancreatitis
    • Sanfey H, Bulkley GB, Cameron JL. The role of oxygen-derived free radicals in the pathogenesis of acute pancreatitis. Ann Surg 1984; 200: 405-413
    • (1984) Ann Surg , vol.200 , pp. 405-413
    • Sanfey, H.1    Bulkley, G.B.2    Cameron, J.L.3
  • 28
    • 0034052439 scopus 로고    scopus 로고
    • Pathophysiologic role of oxygen free radicals in acute pancreatitis: Initiating event or mediator of tissue damage?
    • Rau B, Poch B, Gansauge F, Bauer A, Nüssler AK, Nevalainen T, Schoenberg MH, Beger HG. Pathophysiologic role of oxygen free radicals in acute pancreatitis: initiating event or mediator of tissue damage? Ann Surg 2000; 231: 352-360
    • (2000) Ann Surg , vol.231 , pp. 352-360
    • Rau, B.1    Poch, B.2    Gansauge, F.3    Bauer, A.4    Nüssler, A.K.5    Nevalainen, T.6    Schoenberg, M.H.7    Beger, H.G.8
  • 31
    • 68849125328 scopus 로고    scopus 로고
    • Variations in the levels of oxidative stress and antioxidants during early acute pancreatitis
    • Thareja S, Bhardwaj P, Sateesh J, Saraya A. Variations in the levels of oxidative stress and antioxidants during early acute pancreatitis. Trop Gastroenterol 2009; 30: 26-31
    • (2009) Trop Gastroenterol , vol.30 , pp. 26-31
    • Thareja, S.1    Bhardwaj, P.2    Sateesh, J.3    Saraya, A.4
  • 32
    • 33646053160 scopus 로고    scopus 로고
    • Blood plasma antioxidant defense in patients with pancreatitis
    • Sajewicz W, Milnerowicz S, Nabzdyk S. Blood plasma antioxidant defense in patients with pancreatitis. Pancreas 2006; 32: 139-144
    • (2006) Pancreas , vol.32 , pp. 139-144
    • Sajewicz, W.1    Milnerowicz, S.2    Nabzdyk, S.3
  • 34
    • 0030923560 scopus 로고    scopus 로고
    • Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-alpha. Role in regulating cell death and pancreatitis
    • Gukovskaya AS, Gukovsky I, Zaninovic V, Song M, Sandoval D, Gukovsky S, Pandol SJ. Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-alpha. Role in regulating cell death and pancreatitis. J Clin Invest 1997; 100: 1853-1862
    • (1997) J Clin Invest , vol.100 , pp. 1853-1862
    • Gukovskaya, A.S.1    Gukovsky, I.2    Zaninovic, V.3    Song, M.4    Sandoval, D.5    Gukovsky, S.6    Pandol, S.J.7
  • 37
    • 70449424176 scopus 로고    scopus 로고
    • Cross-talk between oxidative stress and pro-inflammatory cytokines in acute pancreatitis: A key role for protein phosphatases
    • Escobar J, Pereda J, Arduini A, Sandoval J, Sabater L, Aparisi L, López-Rodas G, Sastre J. Cross-talk between oxidative stress and pro-inflammatory cytokines in acute pancreatitis: a key role for protein phosphatases. Curr Pharm Des 2009; 15: 3027-3042
    • (2009) Curr Pharm Des , vol.15 , pp. 3027-3042
    • Escobar, J.1    Pereda, J.2    Arduini, A.3    Sandoval, J.4    Sabater, L.5    Aparisi, L.6    López-Rodas, G.7    Sastre, J.8
  • 39
    • 33749076881 scopus 로고    scopus 로고
    • Redox-sensitive modulation of CD45 expression in pancreatic acinar cells during acute pancreatitis
    • de Dios I, Ramudo L, García-Montero AC, Manso MA. Redox-sensitive modulation of CD45 expression in pancreatic acinar cells during acute pancreatitis. J Pathol 2006; 210: 234-239
    • (2006) J Pathol , vol.210 , pp. 234-239
    • de Dios, I.1    Ramudo, L.2    García-Montero, A.C.3    Manso, M.A.4
  • 40
    • 13844296655 scopus 로고    scopus 로고
    • Dynamics of antioxidants in patients with acute pancreatitis and in patients operated for colorectal cancer: A clinical study
    • Musil F, Zadák Z, Solichová D, Hyspler R, Kaska M, Sobotka L, Manák J. Dynamics of antioxidants in patients with acute pancreatitis and in patients operated for colorectal cancer: a clinical study. Nutrition 2005; 21: 118-124
    • (2005) Nutrition , vol.21 , pp. 118-124
    • Musil, F.1    Zadák, Z.2    Solichová, D.3    Hyspler, R.4    Kaska, M.5    Sobotka, L.6    Manák, J.7
  • 41
    • 77951724120 scopus 로고    scopus 로고
    • Correlation of nitric oxide and other free radicals with the severity of acute pancreatitis and complicated systemic inflammatory response syndrome
    • Que RS, Cao LP, Ding GP, Hu JA, Mao KJ, Wang GF. Correlation of nitric oxide and other free radicals with the severity of acute pancreatitis and complicated systemic inflammatory response syndrome. Pancreas 2010; 39: 536-540
    • (2010) Pancreas , vol.39 , pp. 536-540
    • Que, R.S.1    Cao, L.P.2    Ding, G.P.3    Hu, J.A.4    Mao, K.J.5    Wang, G.F.6
  • 42
    • 33750324819 scopus 로고    scopus 로고
    • Ultrastructural clues for the protective effect of ascorbic acid and N-acetylcysteine against oxidative damage on caerulein-induced pancreatitis
    • Eşrefoǧlu M, Gül M, Ateş B, Yilmaz I. Ultrastructural clues for the protective effect of ascorbic acid and N-acetylcysteine against oxidative damage on caerulein-induced pancreatitis. Pancreatology 2006; 6: 477-485
    • (2006) Pancreatology , vol.6 , pp. 477-485
    • Eşrefoǧlu, M.1    Gül, M.2    Ateş, B.3    Yilmaz, I.4
  • 43
    • 33644903543 scopus 로고    scopus 로고
    • Ultrastructural clues for the protective effect of melatonin against oxidative damage in cerulein-induced pancreatitis
    • Eşrefoǧlu M, Gül M, Ateş B, Selimoǧlu MA. Ultrastructural clues for the protective effect of melatonin against oxidative damage in cerulein-induced pancreatitis. J Pineal Res 2006; 40: 92-97
    • (2006) J Pineal Res , vol.40 , pp. 92-97
    • Eşrefoǧlu, M.1    Gül, M.2    Ateş, B.3    Selimoǧlu, M.A.4
  • 45
    • 0004897150 scopus 로고    scopus 로고
    • Antioxidants: The basics--what they are and how to evaluate them
    • Halliwell B. Antioxidants: the basics--what they are and how to evaluate them. Adv Pharmacol 1997; 38: 3-20
    • (1997) Adv Pharmacol , vol.38 , pp. 3-20
    • Halliwell, B.1
  • 47
    • 29344446328 scopus 로고    scopus 로고
    • Targeting antioxidants to mitochondria: A new therapeutic direction
    • Sheu SS, Nauduri D, Anders MW. Targeting antioxidants to mitochondria: a new therapeutic direction. Biochim Biophys Acta 2006; 1762: 256-265
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 256-265
    • Sheu, S.S.1    Nauduri, D.2    Anders, M.W.3
  • 49
    • 0034660880 scopus 로고    scopus 로고
    • The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase
    • Li S, Yan T, Yang JQ, Oberley TD, Oberley LW. The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res 2000; 60: 3927-3939
    • (2000) Cancer Res , vol.60 , pp. 3927-3939
    • Li, S.1    Yan, T.2    Yang, J.Q.3    Oberley, T.D.4    Oberley, L.W.5
  • 50
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991; 11: 81-128
    • (1991) Free Radic Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 51
    • 0024488257 scopus 로고
    • The antioxidant and nutritional effects of tocopherols, ascorbic acid and beta-carotene in relation to processing of edible oils
    • Frankel EN. The antioxidant and nutritional effects of tocopherols, ascorbic acid and beta-carotene in relation to processing of edible oils. Bibl Nutr Dieta 1989; (43): 297-312
    • (1989) Bibl Nutr Dieta , Issue.43 , pp. 297-312
    • Frankel, E.N.1
  • 52
    • 55549126829 scopus 로고    scopus 로고
    • Effects of ionol and alpha-tocopherol on lipid peroxidation in the liver of dogs with acute pancreatitis
    • Filipenko PS, Saliǐ IS, Potapov GV. Effects of ionol and alpha-tocopherol on lipid peroxidation in the liver of dogs with acute pancreatitis. Patol Fiziol Eksp Ter 2008; (3): 29-31
    • (2008) Patol Fiziol Eksp Ter , Issue.3 , pp. 29-31
    • Filipenko, P.S.1    Saliǐ, I.S.2    Potapov, G.V.3
  • 54
    • 0025726427 scopus 로고
    • Effect of a new synthetic ascorbic acid derivative as a free radical scavenger on the development of acute pancreatitis in mice
    • Nonaka A, Manabe T, Tobe T. Effect of a new synthetic ascorbic acid derivative as a free radical scavenger on the development of acute pancreatitis in mice. Gut 1991; 32: 528-532
    • (1991) Gut , vol.32 , pp. 528-532
    • Nonaka, A.1    Manabe, T.2    Tobe, T.3
  • 56
    • 0034098915 scopus 로고    scopus 로고
    • Relationship of carotenoid and vitamins A and E with the acute inflammatory response in acute pancreatitis
    • Curran FJ, Sattar N, Talwar D, Baxter JN, Imrie CW. Relationship of carotenoid and vitamins A and E with the acute inflammatory response in acute pancreatitis. Br J Surg 2000; 87: 301-305
    • (2000) Br J Surg , vol.87 , pp. 301-305
    • Curran, F.J.1    Sattar, N.2    Talwar, D.3    Baxter, J.N.4    Imrie, C.W.5
  • 62
    • 0029810902 scopus 로고    scopus 로고
    • Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NFkappa B
    • Natarajan K, Singh S, Burke TR, Grunberger D, Aggarwal BB. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NFkappa B. Proc Natl Acad Sci USA 1996; 93: 9090-9095
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9090-9095
    • Natarajan, K.1    Singh, S.2    Burke, T.R.3    Grunberger, D.4    Aggarwal, B.B.5
  • 66
    • 0030890257 scopus 로고    scopus 로고
    • Effects of green tea catechins (Polyphenon 100) on cerulein-induced acute pancreatitis in rats
    • Takabayashi F, Harada N. Effects of green tea catechins (Polyphenon 100) on cerulein-induced acute pancreatitis in rats. Pancreas 1997; 14: 276-279
    • (1997) Pancreas , vol.14 , pp. 276-279
    • Takabayashi, F.1    Harada, N.2
  • 67
    • 0035754146 scopus 로고    scopus 로고
    • Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: A review of the evidence
    • Reiter RJ, Tan DX, Manchester LC, Qi W. Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: a review of the evidence. Cell Biochem Biophys 2001; 34: 237-256
    • (2001) Cell Biochem Biophys , vol.34 , pp. 237-256
    • Reiter, R.J.1    Tan, D.X.2    Manchester, L.C.3    Qi, W.4
  • 69
    • 73649148666 scopus 로고    scopus 로고
    • Melatonin treatment is beneficial in pancreatic repair process after experimental acute pancreatitis
    • Sidhu S, Pandhi P, Malhotra S, Vaiphei K, Khanduja KL. Melatonin treatment is beneficial in pancreatic repair process after experimental acute pancreatitis. Eur J Pharmacol 2010; 628: 282-289
    • (2010) Eur J Pharmacol , vol.628 , pp. 282-289
    • Sidhu, S.1    Pandhi, P.2    Malhotra, S.3    Vaiphei, K.4    Khanduja, K.L.5
  • 72
    • 27644504128 scopus 로고    scopus 로고
    • Delayed neutrophil apoptosis attenuated by melatonin in human acute pancreatitis
    • Chen HM, Hsu JT, Chen JC, Ng CJ, Chiu DF, Chen MF. Delayed neutrophil apoptosis attenuated by melatonin in human acute pancreatitis. Pancreas 2005; 31: 360-364
    • (2005) Pancreas , vol.31 , pp. 360-364
    • Chen, H.M.1    Hsu, J.T.2    Chen, J.C.3    Ng, C.J.4    Chiu, D.F.5    Chen, M.F.6
  • 73
    • 33750484015 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: Discordant in vitro and in vivo dose-effects: A review
    • Sadowska AM, Manuel-Y-Keenoy B, De Backer WA. Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review. Pulm Pharmacol Ther 2007; 20: 9-22
    • (2007) Pulm Pharmacol Ther , vol.20 , pp. 9-22
    • Sadowska, A.M.1    Manuel-Y-Keenoy, B.2    de Backer, W.A.3
  • 74
    • 27944447238 scopus 로고    scopus 로고
    • Pro-and antiinflammatory response of acinar cells during acute pancreatitis. Effect of N-acetyl cysteine
    • Ramudo L, Manso MA, Vicente S, De Dios I. Pro-and antiinflammatory response of acinar cells during acute pancreatitis. Effect of N-acetyl cysteine. Cytokine 2005; 32: 125-131
    • (2005) Cytokine , vol.32 , pp. 125-131
    • Ramudo, L.1    Manso, M.A.2    Vicente, S.3    de Dios, I.4
  • 75
    • 0141924119 scopus 로고    scopus 로고
    • Major pathological mechanisms of acute pancreatitis are prevented by N-acetylcysteine
    • Sevillano S, De la Mano AM, De Dios I, Ramudo L, Manso MA. Major pathological mechanisms of acute pancreatitis are prevented by N-acetylcysteine. Digestion 2003; 68: 34-40
    • (2003) Digestion , vol.68 , pp. 34-40
    • Sevillano, S.1    De la Mano, A.M.2    de Dios, I.3    Ramudo, L.4    Manso, M.A.5
  • 76
    • 44449107022 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on mRNA expression of monocyte chemotactic protein and macrophage inflammatory protein 2 in acute necrotizing pancreatitis: Experiment with rats
    • Xu CF, Wu AR, Shen YZ. Effects of N-acetylcysteine on mRNA expression of monocyte chemotactic protein and macrophage inflammatory protein 2 in acute necrotizing pancreatitis: experiment with rats. Zhonghua Yixue Zazhi 2008; 88: 711-715
    • (2008) Zhonghua Yixue Zazhi , vol.88 , pp. 711-715
    • Xu, C.F.1    Wu, A.R.2    Shen, Y.Z.3
  • 77
    • 34548703824 scopus 로고    scopus 로고
    • Extrapancreatic organ impairment during acute pancreatitis induced by bile-pancreatic duct obstruction. Effect of N-acetylcysteine
    • Manso MA, Ramudo L, De Dios I. Extrapancreatic organ impairment during acute pancreatitis induced by bile-pancreatic duct obstruction. Effect of N-acetylcysteine. Int J Exp Pathol 2007; 88: 343-349
    • (2007) Int J Exp Pathol , vol.88 , pp. 343-349
    • Manso, M.A.1    Ramudo, L.2    de Dios, I.3
  • 78
    • 84856360256 scopus 로고    scopus 로고
    • Hyperbaric oxygen and N-acetylcysteine treatment in L-arginine-induced acute pancreatitis in rats
    • Onur E, Paksoy M, Baca B, Akoglu H. Hyperbaric oxygen and N-acetylcysteine treatment in L-arginine-induced acute pancreatitis in rats. J Invest Surg 2012; 25: 20-28
    • (2012) J Invest Surg , vol.25 , pp. 20-28
    • Onur, E.1    Paksoy, M.2    Baca, B.3    Akoglu, H.4
  • 79
    • 33745432218 scopus 로고    scopus 로고
    • N-acetylcysteine does not prevent post-endoscopic retrograde cholangiopancreatography hyperamylasemia and acute pancreatitis
    • Milewski J, Rydzewska G, Degowska M, Kierzkiewicz M, Rydzewski A. N-acetylcysteine does not prevent post-endoscopic retrograde cholangiopancreatography hyperamylasemia and acute pancreatitis. World J Gastroenterol 2006; 12: 3751-3755
    • (2006) World J Gastroenterol , vol.12 , pp. 3751-3755
    • Milewski, J.1    Rydzewska, G.2    Degowska, M.3    Kierzkiewicz, M.4    Rydzewski, A.5
  • 81
    • 31144439126 scopus 로고    scopus 로고
    • Effect of resveratrol on pancreatic oxygen free radicals in rats with severe acute pancreatitis
    • Li ZD, Ma QY, Wang CA. Effect of resveratrol on pancreatic oxygen free radicals in rats with severe acute pancreatitis. World J Gastroenterol 2006; 12: 137-140
    • (2006) World J Gastroenterol , vol.12 , pp. 137-140
    • Li, Z.D.1    Ma, Q.Y.2    Wang, C.A.3
  • 82
    • 29944444280 scopus 로고    scopus 로고
    • Effect of resveratrol on peritoneal macrophages in rats with severe acute pancreatitis
    • Ma ZH, Ma QY, Wang LC, Sha HC, Wu SL, Zhang M. Effect of resveratrol on peritoneal macrophages in rats with severe acute pancreatitis. Inflamm Res 2005; 54: 522-527
    • (2005) Inflamm Res , vol.54 , pp. 522-527
    • Ma, Z.H.1    Ma, Q.Y.2    Wang, L.C.3    Sha, H.C.4    Wu, S.L.5    Zhang, M.6
  • 83
    • 33845243721 scopus 로고    scopus 로고
    • The study in resveratrol function to acute lung injury sourced from severe acute pancreatitis
    • Wang Z, Ma OY, Ren L, Li ZD, Li L. [The study in resveratrol function to acute lung injury sourced from severe acute pancreatitis]. Sichuan Daxue Xuebao Yixueban 2006; 37: 904-907
    • (2006) Sichuan Daxue Xuebao Yixueban , vol.37 , pp. 904-907
    • Wang, Z.1    Ma, O.Y.2    Ren, L.3    Li, Z.D.4    Li, L.5
  • 86
    • 0021860975 scopus 로고
    • Effects of stilbenes on arachidonate metabolism in leukocytes
    • Kimura Y, Okuda H, Arichi S. Effects of stilbenes on arachidonate metabolism in leukocytes. Biochim Biophys Acta 1985; 834: 275-278
    • (1985) Biochim Biophys Acta , vol.834 , pp. 275-278
    • Kimura, Y.1    Okuda, H.2    Arichi, S.3
  • 87
    • 22144490238 scopus 로고    scopus 로고
    • Resveratrol: A medical drug for acute pancreatitis
    • Ma ZH, Ma QY. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol 2005; 11: 3171-3174
    • (2005) World J Gastroenterol , vol.11 , pp. 3171-3174
    • Ma, Z.H.1    Ma, Q.Y.2
  • 88
    • 78751706732 scopus 로고    scopus 로고
    • The beneficial effect of resveratrol on severe acute pancreatitis
    • Ma Q, Zhang M, Wang Z, Ma Z, Sha H. The beneficial effect of resveratrol on severe acute pancreatitis. Ann N Y Acad Sci 2011; 1215: 96-102
    • (2011) Ann N Y Acad Sci , vol.1215 , pp. 96-102
    • Ma, Q.1    Zhang, M.2    Wang, Z.3    Ma, Z.4    Sha, H.5
  • 89
    • 70350655954 scopus 로고    scopus 로고
    • Protective effect of resveratrol in severe acute pancreatitis-induced brain injury
    • Jha RK, Ma Q, Sha H, Palikhe M. Protective effect of resveratrol in severe acute pancreatitis-induced brain injury. Pancreas 2009; 38: 947-953
    • (2009) Pancreas , vol.38 , pp. 947-953
    • Jha, R.K.1    Ma, Q.2    Sha, H.3    Palikhe, M.4
  • 90
    • 67650739393 scopus 로고    scopus 로고
    • Resveratrol ameliorates lung injury via inhibition of apoptosis in rats with severe acute pancreatitis
    • Sha H, Ma Q, Jha RK, Wang Z. Resveratrol ameliorates lung injury via inhibition of apoptosis in rats with severe acute pancreatitis. Exp Lung Res 2009; 35: 344-358
    • (2009) Exp Lung Res , vol.35 , pp. 344-358
    • Sha, H.1    Ma, Q.2    Jha, R.K.3    Wang, Z.4
  • 91
    • 0038417386 scopus 로고    scopus 로고
    • Antioxidant effect of flavonoids on the susceptibility of LDL oxidation
    • Naderi GA, Asgary S, Sarraf-Zadegan N, Shirvany H. Antioxidant effect of flavonoids on the susceptibility of LDL oxidation. Mol Cell Biochem 2003; 246: 193-196
    • (2003) Mol Cell Biochem , vol.246 , pp. 193-196
    • Naderi, G.A.1    Asgary, S.2    Sarraf-Zadegan, N.3    Shirvany, H.4
  • 93
    • 33846026738 scopus 로고    scopus 로고
    • Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism
    • Lotito SB, Frei B. Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism. J Biol Chem 2006; 281: 37102-37110
    • (2006) J Biol Chem , vol.281 , pp. 37102-37110
    • Lotito, S.B.1    Frei, B.2
  • 95
    • 0034662094 scopus 로고    scopus 로고
    • The importance of selenium to human health
    • Rayman MP. The importance of selenium to human health. Lancet 2000; 356: 233-241
    • (2000) Lancet , vol.356 , pp. 233-241
    • Rayman, M.P.1
  • 96
    • 0038719775 scopus 로고    scopus 로고
    • The antioxidant role of selenium and seleno-compounds
    • Tapiero H, Townsend DM, Tew KD. The antioxidant role of selenium and seleno-compounds. Biomed Pharmacother 2003; 57: 134-144
    • (2003) Biomed Pharmacother , vol.57 , pp. 134-144
    • Tapiero, H.1    Townsend, D.M.2    Tew, K.D.3
  • 97
    • 0037656518 scopus 로고    scopus 로고
    • Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress
    • Klotz LO, Kröncke KD, Buchczyk DP, Sies H. Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress. J Nutr 2003; 133: 1448S-1451S
    • (2003) J Nutr , vol.133
    • Klotz, L.O.1    Kröncke, K.D.2    Buchczyk, D.P.3    Sies, H.4
  • 98
  • 99
    • 0028899908 scopus 로고
    • Decreasing mortality in acute pancreatitis with sodium selenite. Clinical results of 4 years antioxidant therapy
    • Kuklinski B, Zimmermann T, Schweder R. [Decreasing mortality in acute pancreatitis with sodium selenite. Clinical results of 4 years antioxidant therapy]. Med Klin (Munich) 1995; 90 Suppl 1: 36-41
    • (1995) Med Klin (Munich) , vol.90 , Issue.SUPPL. 1 , pp. 36-41
    • Kuklinski, B.1    Zimmermann, T.2    Schweder, R.3
  • 100
    • 0030805410 scopus 로고    scopus 로고
    • Effect of selenium administration on various laboratory parameters in patients with acute pancreatitis
    • Wollschläger S, Ludwig K, Meissner D, Porst H. [Effect of selenium administration on various laboratory parameters in patients with acute pancreatitis]. Med Klin (Munich) 1997; 92 Suppl 3: 22-24
    • (1997) Med Klin (Munich) , vol.92 , Issue.SUPPL. 3 , pp. 22-24
    • Wollschläger, S.1    Ludwig, K.2    Meissner, D.3    Porst, H.4
  • 101
    • 12144266174 scopus 로고    scopus 로고
    • Investigation of antioxidant therapy with sodium selenite in acute pancreatitis. A prospective randomized blind trial
    • Lindner D, Lindner J, Baumann G, Dawczynski H, Bauch K. [Investigation of antioxidant therapy with sodium selenite in acute pancreatitis. A prospective randomized blind trial]. Med Klin (Munich) 2004; 99: 708-712
    • (2004) Med Klin (Munich) , vol.99 , pp. 708-712
    • Lindner, D.1    Lindner, J.2    Baumann, G.3    Dawczynski, H.4    Bauch, K.5
  • 102
    • 79952109132 scopus 로고    scopus 로고
    • Selenium supplementation in patients with severe acute pancreatitis
    • Kocan L, Firment J, Simonová J, Vasková J, Guzy J. Selenium supplementation in patients with severe acute pancreatitis. Rozhl Chir 2010; 89: 518-521
    • (2010) Rozhl Chir , vol.89 , pp. 518-521
    • Kocan, L.1    Firment, J.2    Simonová, J.3    Vasková, J.4    Guzy, J.5
  • 103
    • 23844477620 scopus 로고    scopus 로고
    • Intravenous antioxidant modulation of end-organ damage in L-arginine-induced experimental acute pancreatitis
    • Hardman J, Shields C, Schofield D, McMahon R, Redmond HP, Siriwardena AK. Intravenous antioxidant modulation of end-organ damage in L-arginine-induced experimental acute pancreatitis. Pancreatology 2005; 5: 380-386
    • (2005) Pancreatology , vol.5 , pp. 380-386
    • Hardman, J.1    Shields, C.2    Schofield, D.3    McMahon, R.4    Redmond, H.P.5    Siriwardena, A.K.6
  • 105
    • 34948868191 scopus 로고    scopus 로고
    • Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis
    • Siriwardena AK, Mason JM, Balachandra S, Bagul A, Galloway S, Formela L, Hardman JG, Jamdar S. Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis. Gut 2007; 56: 1439-1444
    • (2007) Gut , vol.56 , pp. 1439-1444
    • Siriwardena, A.K.1    Mason, J.M.2    Balachandra, S.3    Bagul, A.4    Galloway, S.5    Formela, L.6    Hardman, J.G.7    Jamdar, S.8
  • 106
    • 77953242556 scopus 로고    scopus 로고
    • Effect of antioxidant therapy on hospital stay and complications in patients with early acute pancreatitis: A randomised controlled trial
    • Sateesh J, Bhardwaj P, Singh N, Saraya A. Effect of antioxidant therapy on hospital stay and complications in patients with early acute pancreatitis: a randomised controlled trial. Trop Gastroenterol 2009; 30: 201-206
    • (2009) Trop Gastroenterol , vol.30 , pp. 201-206
    • Sateesh, J.1    Bhardwaj, P.2    Singh, N.3    Saraya, A.4
  • 107
    • 80052541159 scopus 로고    scopus 로고
    • Safety and efficacy of vitamin-based antioxidant therapy in patients with severe acute pancreatitis: A randomized controlled trial
    • Bansal D, Bhalla A, Bhasin DK, Pandhi P, Sharma N, Rana S, Malhotra S. Safety and efficacy of vitamin-based antioxidant therapy in patients with severe acute pancreatitis: a randomized controlled trial. Saudi J Gastroenterol 2011; 17: 174-179
    • (2011) Saudi J Gastroenterol , vol.17 , pp. 174-179
    • Bansal, D.1    Bhalla, A.2    Bhasin, D.K.3    Pandhi, P.4    Sharma, N.5    Rana, S.6    Malhotra, S.7
  • 108
    • 0026736361 scopus 로고
    • Anti-oxidative therapy of pancreatitis--an 18-month interim evaluation
    • Kuklinski B, Buchner M, Müller T, Schweder R. Anti-oxidative therapy of pancreatitis--an 18-month interim evaluation. Z Gesamte Inn Med 1992; 47: 239-245
    • (1992) Z Gesamte Inn Med , vol.47 , pp. 239-245
    • Kuklinski, B.1    Buchner, M.2    Müller, T.3    Schweder, R.4
  • 110
    • 33751092781 scopus 로고    scopus 로고
    • Role of enteral nutrition supplemented with ebselen and EHEC in pancreatitis-associated multiple organ dysfunction in rats
    • Zhao H, Lu HG, Shi YB, Zhao LM, Bai C, Wang X. Role of enteral nutrition supplemented with ebselen and EHEC in pancreatitis-associated multiple organ dysfunction in rats. Inflamm Res 2006; 55: 423-429
    • (2006) Inflamm Res , vol.55 , pp. 423-429
    • Zhao, H.1    Lu, H.G.2    Shi, Y.B.3    Zhao, L.M.4    Bai, C.5    Wang, X.6
  • 112
    • 0029114721 scopus 로고
    • Molecular actions of ebselen--an antiinflammatory antioxidant
    • Schewe T. Molecular actions of ebselen--an antiinflammatory antioxidant. Gen Pharmacol 1995; 26: 1153-1169
    • (1995) Gen Pharmacol , vol.26 , pp. 1153-1169
    • Schewe, T.1
  • 113
    • 0011869643 scopus 로고    scopus 로고
    • Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite
    • Sies H, Masumoto H. Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite. Adv Pharmacol 1997; 38: 229-246
    • (1997) Adv Pharmacol , vol.38 , pp. 229-246
    • Sies, H.1    Masumoto, H.2
  • 114
    • 0033994250 scopus 로고    scopus 로고
    • Ebselen: Prospective therapy for cerebral ischaemia
    • Parnham M, Sies H. Ebselen: prospective therapy for cerebral ischaemia. Expert Opin Investig Drugs 2000; 9: 607-619
    • (2000) Expert Opin Investig Drugs , vol.9 , pp. 607-619
    • Parnham, M.1    Sies, H.2
  • 116
    • 56549098403 scopus 로고    scopus 로고
    • Enteral nutrition and the risk of mortality and infectious complications in patients with severe acute pancreatitis: A meta-analysis of randomized trials
    • Petrov MS, van Santvoort HC, Besselink MG, van der Heijden GJ, Windsor JA, Gooszen HG. Enteral nutrition and the risk of mortality and infectious complications in patients with severe acute pancreatitis: a meta-analysis of randomized trials. Arch Surg 2008; 143: 1111-1117
    • (2008) Arch Surg , vol.143 , pp. 1111-1117
    • Petrov, M.S.1    van Santvoort, H.C.2    Besselink, M.G.3    van der Heijden, G.J.4    Windsor, J.A.5    Gooszen, H.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.